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Background Previous studies on the benefits of aerobic exercise mainly focus on the impact of aerobic exercise on long-term cardiovascular health and outcomes, namely regular aerobic exercise can improve arterial stiffness, while some studies point out that high blood sugar increases arterial stiffness. Objective To investigate the immediate effect of aerobic exercise on arterial stiffness in people with different blood glucose levels. Methods This study selected individuals who had participated in the 6th follow-up physical examination of the Kailuan Study during 2018—2020 and participated in the 5th national physical fitness surveillance in 2020 and completed their brachial-ankle pulse wave conduction velocity (baPWV) measured before and after the secondary load test of the power vehicle bicycle in four subordinate enterprises of Kailuan Group. Epidemiological survey result were collected: general information (age, hypertension, hyperlipidemia, history of antihypertensive drugs, etc.) , anthropometric indicators〔systolic blood pressure (SBP) , diastolic blood pressure (DBP) , etc.〕and biochemical indicators (fasting blood glucose, etc.) . baPWV measured in the secondary load test of the power vehicle bicycle (used as the aerobic exercise) was used as an indicator of upper and lower limb arterial stiffness. baPWV-related indicators〔SBP, DBP, mean arterial pressure (MAP) , heart rate (HR) , baPWV, metabolic equivalent (MET) , maximal oxygen uptake (VO2max) , etc.〕before and after the test were expressed using a unified form, for example, pre- and post-test baPWV were recorded as baPWV1 and baPWV2, respectively, and its pre- and post-test difference was denoted as ?baPWV. The epidemiological survey result and BAPWV-related data were compared between fasting blood glucose (FBG) quartile groups〔Q1 (n=220) :

The participation of wind power in grid frequency support is pivotal to maintaining the safe and stable operation of the grid. MATLAB， as common simulation software， can only build small-scale power system models containing wind power， and the simulation speed is low. To carry out wind power frequency support control research in MATLAB and improve the research efficiency， a fast simulation model based on the simplified model of wind turbine and grid frequency response model is constructed. Then， a method is proposed to obtain the SFR （system frequency response） model excluding the wind power frequency support. Finally， the validity and efficiency of the fast simulation model are verified by the example. The results show that the frequency response of the constructed fast simulation model is consistent with the complete power system model， and the simulation speed of the wind farm can be increased by more than 130 times when a single unit equivalent is used， and by nearly 1，100 times when all units of the wind farm are retained， which significantly improves the efficiency of wind power participation in grid frequency support research under MATLAB software.

Objective: To study the association between three single nucleotide polymorphisms (SNP; rs2241766, rs1501299 and rs12495941) variants of the adiponectin gene (ADIPOQ) and polycystic ovary syndrome (PCOS) in PCOS family trios., Methods: A total of 224 unrelated PCOS probands, their biological parents were recruited. Anthropometric variables such as waist circumference (WC), hip circumference (HC), height and weight were measured in all subjects during the first visit to the outpatient department. Body mass index (BMI) and waist- hip ratio (WHR) were calculated. Serum fasting glucose (FBG), fasting insulin (FINS), total cholesterol (TC), triglycerides (TG), low- density lipoprotein and highdensity lipoprotein cholesterol (HDL) levels were measured. PCOS patients were divided into two groups based on BMI: group A (BMI<25 kg/m²) and group B (BMI ≥ 25 kg/m²). Parents of PCOS patients were accordingly categorized into group C, D (fathers) and group E, F (mothers). The transmission disequilibrium test (TDT) was used to analyze the association between three SNP of ADIPOQ and PCOS., Results: (1) A significant positive association was detected between SNP rs1501299 and PCOS (χ² = 7.093, P = 0.008). However we failed to find significant overtransmission of the other two SNP rs2241766 and rs12495941 from parents to PCOS offsprings (χ² = 1.620, P = 0.203; χ² = 0.713, P = 0.398). (2) Linkage disequilibrium (LD) was analyzed in the subjects, rs1501299 and rs2241766 were in weak LD (r² = 0.063, D' = 0.621). (3) The levels of WC, HC, WHR, testosterone, TG, HDL and FINS were significantly differences between obese and lean PCOS patients (P < 0.05). While in fathers we only found WC, HC, TC levels being statistically different (P < 0.05). Mothers of obese PCOS patients had increased levels of FINS compared with mothers of lean PCOS patients (P < 0.05). The genotype frequencies of the three SNP were not different in obese and lean PCOS patients and their parents (P>0.05)., Conclusions: TDT confirms that SNP rs1501299 in the ADIPOQ is significantly associated with the risk of PCOS in the Chinese Han population. The three SNP of the ADIPOQ were not associated with the obesity of PCOS.