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The carbon cloths made of carbon fiber as 3D integrated cathode for lithium-ion batterie were studied. The graphitization degree of three types of carbon cloths after heat treatment were qualitatively analyzed and quantitatively calculated. Using lithium metal as the counter electrode, the graphitized carbon cloth electrodes show first discharge specific capacities of 83.6, 94.5 mAh∙g-1 and 115.2 mAh∙g-1 under 0.1-0.5 V, respectively. After 50 cycles, the specific capacities of carbon cloth electrodes remain 55.0, 80.0 mAh∙g-1 and 88.0 mAh∙g-1.With LiFePO4-loaded graphitized carbon cloths as cathodes, the initial discharge specific capacities of electrodes are 73.2, 109.5 mAh∙g-1 and 130.2 mAh∙g-1, respectively. The carbon cloth whose graphitization degree is 76.02% shows stable specific capacity of about 90.0 mAh∙g-1 after 50 cycles, and shows better comprehensive performances. This carbon cloth is more suitable for the integrated flexible cathode of lithium-ion batteries. By establishing the mechanical model of the interaction between LiFePO4 particles and carbon fiber, the relationship between mechanical, electrical and electrochemical properties of the integrated cathode were discussed.Using carbon cloth as an integrated cathode for lithium-ion batteries can simplify the conventional production process and innovate its production process.

Morchella sextelata was used as experimental material to explore the effects of NaCl stress on mycelia growth and physiological indexes. The mycelial growth index, mycelial morphology, biomass, mycelial membrane permeability, osmotic regulatory substance content and antioxidant enzymes of M. sextelata were measured under different concentrations of NaCl (0, 100, 200, 300, 400 and 500 mmol/L). The effects of different levels of NaCl stress on mycelial growth and resistance physiology of M. sextelata were analyzed. Correlation analysis and principal component analysis were used to screen the key physiological indexes during the mycelial growth of M. sextelata under different NaCl concentrations. The results indicated that as the concentration of NaCl in the medium increased, the mycelial growth rate, mycelial biomass, mycelial diameter and intercellular polysaccharide (IPS) content of M. sextelata showed a downward trend, while the osmotic pressure (OP) and electrical conductivity (EC) showed an upward trend. The soluble protein content, malondialdehyde (MDA) content, proline (Pro) content, superoxide dismutase (SOD) activity, peroxidase (POD) activity and catalase (CAT) activity all increased first and then decreased with the increasing of NaCl concentration. At 200 mmol/L NaCl concentration, the malondialdehyde (MDA) content, peroxidase (POD) activity and catalase (CAT) activity peaked, proline content and SOD activity peaked at 300 mmol/L salt concentration, while soluble protein content peaked at 400 mmol/L NaCl concentration. Through principal component analysis, the accumulative contribution rate of the first three principal components was 96.611%. Among them, when NaCl concentration was 0~100 mmol/L, the indicative physiological indexes were growth rate, mycelial diameter, dry weight, fresh weight and IPS content. When NaCl concentration was 100~200 mmol/L, the indicative physiological indexes were MDA content, soluble protein content, SOD activity, POD activity and CAT activity. When NaCl concentration was 200~400 mmol/L, the indicative physiological indexes were Pro content, soluble protein content and SOD activity.

In order to study the stereo garage frame structure stability and displacement of frame under earthquake load response,combined with the theory of modal analysis and extraction method,using ANSYS finite element software to frame modal calculation,and extract the natural frequencies and mode shapes of order 8 of its former. The EI Centro earthquake wave which is similar to the seismic requirements has been chosen for simulated seismic wave which is used to analyze the deformation of the frame. The results show that the natural frequency of the frame is lower,and the resonance phenomenon may occur due to the external load. The frame natural frequency should be avoided similar to the external load vibration frequency. The displacement response of each frame node under the action of simulating seismic waves is between- 30 mm 35 mm,and the value is far less than the material yield limit. That suggests the seismic performance of three-dimensional parking spaces can meet the requirements.

In order to improve the accuracy of near infrared (NIR) spectroscopy identification methods for tea at different altitude, the non-linear manifold dimensionality reduction methods of locally linear embedding (LLE) and laplacian eigenmaps (LE) were used to reduce the dimension of NIR spectral data, and compared with non-linear (KPCA) and linear (PCA) dimensional reduction methods. Discrimination models were established for tea at different altitude based on different dimensional reduction methods and least squares support vector machine (LSSVM) algorithm. Visualization of different dimensionality reduction results show that data processed by KPCA and PCA methods were more discrete. In particular, there were more overlaps between 400-800 m and 800-1 200 m samples. However, the same kind of sample points could be gathered well in three-dimensional space by the nonlinear manifold dimensionality reduction methods can. Tea at different altitude could be easily separated and the aggregation effect of the LE was better than that of the LLE. The results of models indicate the LE_LSSVM model had the best performance, with the prediction set accuracy and Kappa value of 100% and 1.00 respectively. Compared with PCA_LSSVM, KPCA_LSSVM and LLE_LSSVM models, the accuracy of prediction set was improved by 1.7%, 1.7%, 3.3% and Kappa values increased by 0.025, 0.03, and 0.05. The results show that LE and other nonlinear manifold dimensionality reduction methods were effective in reducing dimension of near infrared spectral data, simplifying model complexity, and improving model precision. The study provides a new means for rapid detecting for tea quality research. [ABSTRACT FROM AUTHOR]

According to the demands of teacher management platform in network remote experiment, this paper uses of ASP. NET technology, Ct language and SQL database technology, designs the information batch import function of the network remote experiment using B/S mode. Based on the mechanism of student information management, teachers use Web browser to connect to the remote experimental platform via the Internet. To begin with, the inputted student registration information is identified by the system, and the system determines whether the input is valid and gives the administrator the appropriate prompts. Then, the techers make the inputted valid users ' information match with the information which is successfully registered by system. At the end, the unmatched information will do the batch import. At the same time, the techers will display the inputted student information in the form of the web so that teachers could scan and check the information. In this process, the teacher not only could achieve the recognition of the validity of the information input, but also could implement efficient entry of student information and smart match. And it provides convenience for the information management of the network remote experiment. [ABSTRACT FROM AUTHOR]

Against the problems of privacy leakage caused by the structure of office workflow diagram, this paper constructed a privacy protection model for office automation systems, which proposes an unified anonymization algorithm for actual 1-neighbourhood nodes protecting and the minimum random disturbance method for weights protecting based on the idea of social network anonymization. The model was effectively useful for preventing attackers from recognizing important nodes in an office network by the information of background, the nodes degree and workflow between different nodes, which has been scientifically verified about its usability by experiments. [ABSTRACT FROM AUTHOR]

This paper proposes an improved adaptive importance sampling method that can be used for variables following a GEV distribution. The L-moment method is employed to build the relationship between sample statistics and distribution parameters. In the case study, the 24-hour design storm of Yungang Basin in Zhejiang Province is considered, and the probability of extreme precipitation is calculated for two rainfall gauge stations, Jinzhuling and Xianrentan. The results show that the proposed method performs well in simulating extreme rainfall, and the iterative number decreases as the number of samples increases. Compared with traditional MC simulation, the improved adaptive importance sampling method has better efficiency. Besides, this method has huge potential to be used for other distributions. [ABSTRACT FROM AUTHOR]

Objective: The present study intended to analyze the characteristics of intestinal floral composition and the relationship with serum cytokines in individuals with egg allergy. Methods: A total of 20 subjects were recruited in this study. The abundance and composition of intestinal flora were determined by 16S rRNA gene sequencing, and the serum levels of food allergy-related cytokines such as interleukin-4 (IL-4) and IL-5 were measured by enzyme immunoassay. The differences in the structure of intestinal flora and the levels of cytokines were compared between the egg allergy and control groups and the correlation between them was analyzed. Results: The serum levels of IL-4 and IL-5 were significantly higher in the egg allergy group compared with the control group (P < 0.05). 16S rRNA gene sequencing showed that Betaproteobacteriales, Burkholderiaceae and Eubacterium_hallii group were significantly enriched in the allergy group (P < 0.05). Spearman’s correlation analysis revealed a negative correlation between the abundance of Weissella cibaria and Escherichia and the serum levels of IL-4 and IL-13. However, the abundance of Burkholderiaceae and uncultured_Parasutterella abundance was positively correlated with transforming growth factor beta1 (TGF-β1) and IL-13. Conclusion: This study provides a scientific basis for determining the specific intestinal flora of egg-allergic individuals and for exploring the implication of intestinal flora in preventing or treating egg allergy.

Objective To develop a deep learning model for automated age estimation based on 3D CT reconstructed images of Han population in western China, and evaluate its feasibility and reliability. Methods The retrospective pelvic CT imaging data of 1 200 samples （600 males and 600 females） aged 20.0 to 80.0 years in western China were collected and reconstructed into 3D virtual bone models. The images of the ischial tuberosity feature region were extracted to create sex-specific and left/right site-specific sample libraries. Using the ResNet34 model, 500 samples of different sexes were randomly selected as training and verification set, the remaining samples were used as testing set. Initialization and transfer learning were used to train images that distinguish sex and left/right site. Mean absolute error （MAE） and root mean square error （RMSE） were used as primary indicators to evaluate the model. Results Prediction results varied between sexes, with bilateral models outperformed left/right unilateral ones, and transfer learning models showed superior performance over initial models. In the prediction results of bilateral transfer learning models, the male MAE was 7.74 years and RMSE was 9.73 years, the female MAE was 6.27 years and RMSE was 7.82 years, and the mixed sexes MAE was 6.64 years and RMSE was 8.43 years. Conclusion The skeletal age estimation model, utilizing ischial tuberosity images of Han population in western China and employing the ResNet34 combined with transfer learning, can effectively estimate adult ischium age.

Mucinous ovarian cancer (MOC) is a rare pathological type different from epithelial ovarian cancer, and the clinical treatment should refer to serous ovarian cancer (SOC) guidelines. However, since the clinicopathological features of MOC are significantly different from SOC, careful differentiation is needed in diagnosis and treatment. Surgery combined with adjuvant chemotherapy is the standard treatment for MOC. However, due to the low prevalence rate, it is difficult to carry out clinical trials, hence lacking evidence-based medicine and consensus on the indications of intraoperative appendectomy and the choice of postoperative adjuvant chemotherapy. In addition, further translational preclinical studies of targeted therapy and immunotherapy are needed to facilitate the diagnosis and individualized treatment of MOC.

Background Low shearing force can induce vascular inflammatory response, which leads to the occurrence and development of hypertension. Estrogen can regulate the immune system and inflammatory response through estrogen receptor mediated pathway, with a protective effect on hypertension. Cardiovascular diseases have become the leading cause of death in China. Objective To investigate the current prevalence and influencing factors of hypertension in women, explore the correlation of shearing force and estradiol with hypertension as well as the effect of estradiol on hypertension under various shearing force, so as to further explore the effect of the interaction between estradiol and shearing force on hypertension. Methods Female patients admitted to the Department of Cardiology of Hunan People's Hospital from January to August 2021 were selected as the study subjects, 288 of whom with essential hypertension were included as the case group, and 296 female non-hypertensive medical examiners in the physical examination department of Hunan People's Hospital were randomly selected as the control group. The self-designed questionnaire was used to investigate the general information of the study subjects, and the fasting venous blood samples of the subjects were taken in the early morning for the examination of laboratory indicators. The color doppler ultrasound was used for ultrasonography on vessels to calculate the shearing force. Multivariate Logistic regression was used to construct the hypertension prediction model and draw the nomogram. Receiver operating characteristic curve (ROC curve) was plotted to evaluate the hypertension prediction model. Stratification analysis was conducted on estradiol in four groups to explore the effect of each estradiol group on the occurrence of hypertension under different shearing force dichotomous groups. The multiplicative interaction model was used to evaluate the interaction between estradiol and shearing force. Results There were significant differences in age, education level, body mass index (BMI), menopause, family history of hypertension, triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), estradiol, uric acid (UA), creatinine (Scr), urea nitrogen (BUN), shear force, and blood viscosity between the case group and control group (P60 years old〔OR=2.172, 95%CI (1.361, 3.468) 〕, menopause〔OR=14.940, 95%CI (1.938, 115.176) 〕, family history of hypertension〔OR=1.614, 95%CI (1.014, 2.570) 〕, BMI of 24-28 kg/m2〔OR=3.454, 95%CI (2.072, 5.758) 〕, BMI>28 kg/m2〔OR=6.750, 95%CI (2.380, 19.146) 〕, TG of 1.30-1.83 mmol/L〔OR=1.980, 95%CI (1.114, 3.520) 〕, TG>1.83 mmol/L〔OR=2.311, 95%CI (1.308, 4.082) 〕, TC of 4.29-5.12 mmol/L〔OR=2.222, 95%CI (1.250, 3.950) 〕, TC>5.12 mmol/L〔OR=1.884, 95%CI (1.062, 3.341) 〕, LDL-C>2.81 mmol/L〔OR=1.546, 95%CI (1.150, 2.078) 〕, HDL-C>1.17 mmol/L〔OR=0.140, 95%CI (0.065, 0.301) 〕, BUN>5.47 mmol/L〔OR=3.249, 95%CI (2.380, 4.434) 〕, Scr>69 μmol/L〔OR=1.166, 95%CI (1.126, 1.207) 〕, UA>324 μmol/L〔OR=1.040, 95%CI (1.029, 1.050) 〕, WBV4.41 mPa·s〔OR=3.456, 95%CI (2.557, 4.671) 〕, estradiol of 10.60-23.99 ng/L〔OR=0.005, 95%CI (0.001, 0.020) 〕, shearing force >8.21 dyne/cm2〔OR=0.033, 95%CI (0.017, 0.062) 〕were influncing factors for hypertension (P8.21 dyne/cm2 group, estradiol≥15.39 ng/L was significantly associated with reduced risk of hypertension〔OR=0.012, 95%CI (0.005, 0.019), P

ObjectiveTo examine the relationship between intestinal flora and bone mineral density among rural Han residents aged 55 – 65 years in Taizhou city, Jiangsu province for exploring novel approaches to osteoporosis prevention. MethodsUsing cluster random sampling, we recruited 537 rural Han long term (≥ 20 years) residents aged 55 – 65 years in 3 villages with more compliant followees and high response rate in a cohort for multidisciplinary and multiple diseases research – the Taizhou Longitudinal Study. Questionnaire interview, physical examination, bone density measurement and stool specimen detection were carried out among the selected residents from March 2013 through October 2018. The residents were then assigned into one of the 3 groups with normal bone density, osteopenia and osteoporosis based on bone density measurement according to the diagnostic criteria of World Health Organization. Differences in intestinal flora among the 3 groups and the correlation between intestinal flora and bone density were analyzed. ResultsOf all the participants, 38.55% (207), 44.51% (239), and 16.94% (91) were assessed with normal bone density, osteopenia, and osteoporosis, respectively. After adjusting for variables such as gender, age, body mass index (BMI), smoking and alcohol drinking, the results of partial correlation analysis showed that intake frequency of fresh vegetables (β = – 0.125), fresh fruits (β = – 0.101), meat (β = – 0.098) ) and yogurt (β = – 0.033) were reversely correlated significantly with bone mineral density grouping (all P < 0.05). Compared with those in the normal bone density group, the intestinal abundances of Clostridium, Blautia, Campylobacter, Escherichia, Streptococcus, Actinomyces, Shigella, Anaerostipes, Streptomyces and Atopobium were significantly decreased in both osteopenia and osteoporosis group; but the intestinal abundances of Corynebacterium, Veillonella and Brevundimonas increased in osteopenia and osteoporosis group (all P < 0.05). After adjusting for confound-ing factors such as gender, age, BMI, smoking, alcohol drinking, and intake frequency of fresh vegetable/fresh fruit/ meat/yogurt, the results of unconditional multivariate logistic regression analysis showed that the increased intestinal relative abundance of Escherichia (odds ratio [OR] = 0.992, 95% confidence interval [95% CI]: 0.985 – 0.999), Shigella (OR = 0.984, 95% CI: 0.970 – 0.998), Blautia (OR = 0.959, 95% CI: 0.924 – 0.996) and Fusicatenibacter (OR = 0.980, 95% CI: 0.962 – 0.998) are protective factors for the occurrence of osteopenia in the residents; the intestinal relative abundance of Faecalibacterium (OR = 1.060, 95% CI: 1.006 – 1.118) is a risk factor for osteoporosis incidence, while that of Mogibacterium (OR = 0.865, 95% CI: 0.763 – 0.981) is a protective factor for osteoporosis incidence. ConclusionIn 55 – 65 years old rural Han residents, intestinal flora may associate with bone density; increased intestinal abundance of Escherichia , Shigella, Blautia, Fusicatenibacter, Faecalibacterium, and Mogibacterium could affect bone mineral density of the population.

The hydrogen embrittlement sensitivity of L80 steel under different hydrogen pressure at room temperature was evaluated this work. The variation rules of hydrogen embrittlement sensitivity of L80 steel at hydrogen pressure from 3 MPa to 12 MPa were studied by notch slow strain tensile test combined with fracture analysis. Results showed that L80 steel had no obvious brittleness at room temperature under hydrogen pressure of lower than 5 MPa, and yet had obvious brittleness under hydrogen pressure of more than 8 MPa. Under hydrogen pressure from 3 MPa to 12 MPa, the micro morpholgy at the center of the main section of L80 steel tensile sample changed from dimple morphology to coexistence of dimple morphology and cleavage morphology. The micro morphology at the edge gradually changed from dimple morphology to cleavage. In addition, the change rate of section shrinkage gradually increased from 16.19% to 46.79%. With the increase of hydrogen pressure, the plastic loss of L80 steel increased, the fracture showed obvious embrittlement characteristics, and the hydrogen embrittlement sensitivity gradually increased.

N6-methyladenosine (m6A) RNA modification is a post-transcriptional modification occurring on the 6th N atom of RNA adenine (A), regulating the structure, stability, splicing, output, translation and decay of mRNA, and thus extensively affecting the life processes of various organisms.This paper summarized the role and mechanism of various m6A methylase in the occurrence and development of reproductive system diseases and breast caner, in order to provide new basis for early diagnosis, treatment and improved prognosis of reproductive system diseases and breast caner.

BACKGROUND Quantitative analysis of ancient glass and vitreous materials has important significance for studying its production time, origin, source of raw materials and production process. Compared with traditional analysis methods (eg. EMPA, EDX-SEM), LA-ICP-MS can be used to analyze the primary, minor and trace elements in samples quickly and accurately. OBJECTIVES To investigate the composition of archaeological glass and discriminate its sources. METHODS The element concentration in ancient glass and vitreous materials were determined by LA-ICP-MS. The surface morphologies of pits in glasses were displayed by AFM. RESULTS The matrix effect among NIST610 and Corning A-D was insignificant under 193nm laser system and this experimental condition. A quantification strategy based on NIST610 and normalization to 100% (w/w) was suitable for analyzing Corning A-D and ancient glass samples. Study on different ablation modes in the experiment is helpful for the establishment of different experimental conditions to meet the requirement of different studies. CONCLUSIONS Unearthed samples were analyzed, which provided data support for the source of the product.

Based on the data from drilling, core samples, etc., taking the Lower Cambrian Qiongzhusi Formation and the Lower Silurian Longmaxi Formation shales as study target area, authors investigated the accumulation conditions of marine shale gas from the Lower Paleozoic in the south region of Sichuan Basin. The results indicate that the Qiongzhusi Formation and the Longmaxi Formation black shales in this region are mainly formed in shelf sedimentary facies. The study region features great organic-rich shale thickness, high organic abundance (average TOC >2%), Type I and II organic matter, high-over thermal evolution level, rich in brittle mineral, abundant in micro- and nanometer pores, and high gas content, which are in favor of the generation and enrichment of shale gas. Compared with the shales in North America, in which the shale gas has been explored and developed successfully, it is suggested that the Lower Paleozoic in the south region of Sichuan Basin has good accumulation conditions for shale gas. Therefore, the Qiongzhusi and Longmaxi Formations are considered as the practical targets for shale gas exploration, and their favourable areas of shale gas enrichment are also purposed. [ABSTRACT FROM AUTHOR]

In this paper, the research has been conducted by the Microsoft kinect for windows v2 for obtaining the walking trajectory data from hemiplegic patients, based on which we achieved automatic identification of the hemiplegic gait and sorted the significance of identified features. First of all, the experimental group and two control groups were set up in the study. The three groups of subjects respectively completed the prescribed standard movements according to the requirements. The walking track data of the subjects were obtained straightaway by Kinect, from which the gait identification features were extracted: the moving range of pace, stride and center of mass (up and down/left and right). Then, the bayesian classification algorithm was utilized to classify the sample set of these features so as to automatically recognize the hemiplegia gait. Finally, the random forest algorithm was used to identify the significance of each feature, providing references for the diagnose of disease by ranking the importance of each feature. This thesis states that the accuracy of classification approach based on bayesian algorithm reaches 96%; the sequence of significance based on the random forest algorithm is step speed, stride, left-right moving distance of the center of mass, and up-down moving distance of the center of mass. The combination of step speed and stride, and the combination of step speed and center of mass moving distance are important reference for analyzing and diagnosing of the hemiplegia gait. The results may provide creative mind and new references for the intelligent diagnosis of hemiplegia gait.

Targeted therapy has become a powerful approach for cancer treatment. Better understanding of oncogenes as well as synthetic lethal interactions with oncogenes will lead to new strategies for tumor-specific treatment. It is well known that mutant p53 plays an important role in tumorigenesis and tumor development. Thus, understanding the synthetic lethal relationship between p53 mutations and interacting genes in tumor is critical for the personalized treatments of p53 mutant tumors. Synthetic lethal genes to mutant p53 can be divided into cell cycle regulators and non-cell cycle regulators. This paper review show these two types of target genes contribute to synthetic lethal interactions with p53 mutations and potential applications of these interactions in anticancer therapy.

Objective: To investigate the difference in color pattern reversal visual evoked potential (CPR-VEP)between primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) patients., Methods: Vision Monitor visual electrophysiograph made by Metro Vision Inc. in France was used to record CPR-VEP in 17 eyes of 12 POAG patients, 56 eyes of 41 PACG patients, and 26 eyes of 13 age-equivalent normal persons at an ascending series of temporal frequency (1, 2, 4, 8, 16, and 32 Hz) and color stimulation (black/white, red/green, and blue/yellow). P(100) wave amplitudes and latencies of these patients were compared respectively with those of the normal group., Results: With black/white stimulation, the P(100) wave amplitudes were reduced with the increase of temporal frequency in the 3 groups. The P(100) wave latencies were extended with the increase of temporal frequency with different color stimulations. The P(100) amplitudes were PACG group > NC group > POAG group and black/white > blue/yellow > red/green. The P(100) wave latencies in the POAG group and the PACG group were extended compared with the NC group, but there was no significant difference between PACG group and POAG group., Conclusion: CPR-VEP P(100) amplitudes in the PACG group and POAG group have their own characteristics. The P(100) amplitude of PACG is higher, and POAG is lower than normal. The P(100) wave latencies of PACG and POAG are extended.

Objective: To investigate the changes of color pattern reversal visual evoked potential (CPR-VEP)of primary glaucoma using different temporal frequencies, and to search for the best temporal frequency parameters and color parameters., Methods: Vision Monitor visual electrophysiograph (Métrovision, France) was used to record CPR-VEP at different temporal frequencies (1, 2, 4, 8, 16, and 32 Hz) and different color stimulations (black/white, red/green, blue/yellow) in 41 cases (70 eyes) with primary glaucoma (glaucoma group) and 13 normal subjects (26 eyes) (normal control group). P100 wave amplitudes were compared., Results: (1) In the normal control group, P100 amplitudes declined while the temporal frequency of black/white stimulation was increasing, but they had peaks at 2 Hz and 8 Hz red/green stimulation and blue/yellow stimulation. (2) In the glaucoma group, CPR-VEP P100 declined while temporal frequency was increasing under 3 color stimulations, but had a peak at 8 Hz. At 2 Hz-16 Hz, P100 amplitudes were related with the mean defect of Humphrey visual field, especially with all 3 color stimulations at 8 Hz and with blue/yellow stimulation at 2 Hz and 16 Hz. (3) P100 amplitude was most different under the 3 color stimulations between the 2 groups at 8 Hz., Conclusion: The changes of CPR-VEP P(100) amplitude can objectively reflect the glaucoma visual function damage. CPR-VEP P100 amplitude has certain value in studying glaucoma under different color stimulations (black/white, red/green, blue/yellow) at 8 Hz, and blue/yellow stimulation at 2 Hz and 16 Hz.

Technical framework for water environment simulation of contaminations is established based on visualization and a spatial environmental model is built. The main two contaminations, namely NH: -N and TP, are simulated on the platform of MapInfo and Delft3D in the Qiantang River at the low water period, to analyze its space-time diversity. For NH4+ -N, the measured values are 0.19 mg/L and 0.66 mg/L larger than simulated values at the Lanjiang River mouth and the Yanlingwu, 0.16 mg/L, 0.54 mg/L and 0.49 mg/L smaller at the Zhaixi, the Yushan and the Yuanpu. For TP, the measured values are 0.13 mg/L and 0.14 mg/L higher than simulated values at the Meicheng Water facility and Yanlingwu. However, the measure values are slightly lower than simulated ones at Zhaixi, Yushan, Puyang River mouth and Yuanpu, the trend of which accords with actual situation. The results indicate that the contaminations of the Qiantang Reach mostly come from the Lanjiang River, the Fuchun River and the Puyang River on the upstream, among which the Lanjiang River and the Puyang River have a very high concentration of polluted materials, which means bad water quality, and influence the water downstream. The Lanjiang River becomes the chief contaminative source in the Fuchun River. When the discharge from the Xin'an River Dam is small, the recirculation region may be formed and makes part of the Xin'an Reach contaminated. Otherwise, when the discharge is large, the water quality in the Fuchun River is apparently improved. And the Puyang River, which brings the contaminations from the upstream, along with the polluted water let into it from the industries along the reach, has significant impacts on the water quality in Qiantang Reach.