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In order to meet the needs for cultivation of complex and innovative talents, the theory of quality function deployment is applied to the instructional design for the virtual simulation training course of business management. First, the demand analysis of the course is carried out, the curriculum requirements are transformed into the design of teaching process. Then, the teaching process design is transformed into the employment direction of the students. Some improvement measures for the course design are proposed to promote the teaching quality. [ABSTRACT FROM AUTHOR]