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Taking E141A constant deceleration braking system in JKMD 4.5×4 mine hoist as research object, working principle of the constant deceleration braking system was analyzed. A simulation model of the constant deceleration braking system was built and reliability of the simulation model was verified by theoretical calculation. Typical faults such as spring stiffness decrease, friction factor of brake shoe decrease and brake leakage were simulated. The simulation results show that performance degradation of main components cannot immediately cause failure of the braking system, but can cause system performance degradation such as braking system pressure degradation, braker clearance smaller or bigger, etc. The braking system performance degradation with a certain degree will cause faults such as unsatisfactory braking deceleration, no braker clearance, too large braker clearance, too long idle motion time, etc.

Objective: To compare the effects of oblique insertion at anatomical points and conventional acupuncture for sacroiliac joint injury., Methods: Eighty patients were randomly divided into an observation group and a control group, 40 cases in each one. In the observation group, oblique insertion therapy at anatomical points was used, and the 9 points of equal division (anatomical points) marked by palpating the anatomical symbol were treated as the insertion acupoints. In the control group, conventional acupuncture was applied, and perpendicular insertion was adopted at Huantiao (GB 30), Zhibian (BL 54) and Weizhong (BL 40), etc. In the two groups, the! treatment was given once a day and 5 times per week. Ten treatments were made into one course and two courses were required. The clinical effects, the changes of visual analogue scale (VAS) and Oswestry dysfunctional index. (ODI) before and after treatment were observed in the two groups., Results: The total effective rate of the observation group was 90.0% (36/40), which was better than 72.5% (29/40) of the control group (P < 0.05). After treatment, the results of the VAS and ODI of the two groups were apparently declined (both P < 0.01), and those in the observation group were decreased more obviously (both P < 0.01)., Conclusion: The effect of oblique inser-tion at anatomical points for sacroiliac joint injury is superior to that of conventional acupuncture, which can effectively relieve pain and improve the disfunction.

Objective: To carry out genetic analysis for two patients affected with congenital heart disease, developmental delay with or without cleft palate., Methods: Cytogenetic and molecular genetic methods including karyotyping, fluorescence in situ hybridization (FISH), multiplex ligation-dependent probe amplification (MLPA) and single nucleotide polymorphisms array (SNP-array) were employed to detect potential mutations. For parents of both patients, MLPA was used to analyze whether they were carrier of the deletion., Results: For neither patient, no abnormality was detected upon karyotype analysis. However, FISH analysis has indicated the presence of 22q11.2 deletion. SNP-array analysis has confirmed that both patients have carried a 2.5 Mb deletion in the 22q11.2 region. MLPA analysis suggested none of the parents has carried the same deletion., Conclusion: Although the phenotypes of our patients were not identical, they were both diagnosed as 22q11.2 deletion syndrome by multiple methods. The deletions in both cases were de novo in nature. Precise delineation of the genotype can facilitate better understanding of the patients' phenotype.