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Under the culture temperature 35 °C, shaking frequency 150 r/min, culture pH value 7.0 and culture time 72 h, the quantity of lycopene-degrading reached 224.4 mg/L by Bacillus cereus strain L16 with 300 mg/L lycopene in the medium. The degradation products analyzed by GC-MS were 6-methyl-5-hepten-2-one and isopropyl ketone, which were the characteristic aromatic components for tobacco. [ABSTRACT FROM AUTHOR]