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Gliomas are the most common primary intracranial tumors in adults, among which high-grade glioma patients are characterized by short survival and poor prognosis. The diagnosis, treatment, evaluation of effective treatments, and prognosis prediction of high-grade gliomas are of great significance for improving patient survival. Conventional enhanced magnetic resonance imaging has deficiencies in delineating tumor extent, identifying tumor progression and treatment-related changes. Therefore, there is a broad consensus to incorporate amino acid PET, and 18F-FET PET inparticular, into the diagnostic and therapeutic process of high-grade gliomas. In this article, we review the new research progress of 18F-FET PET in the diagnosis and treatment of adult high-grade glioma in recent years.

Objective: To compare and analyze the positron emission tomography (PET) images with other multi-modalities in the diagnosis of hepatic tumors., Methods: A total of 158 patients undergoing (18)F fluorodeoxyglucose (FDG)-PET were enrolled along with another 55 cases with (11)C acetate-PET (AC-PET) imaging within 1 week. The pathological results were taken as the golden criteria. Tumor marker, contrast ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) results were collected.SPSS 19.0 was used for statistical analysis., Results: Contrast MRI, ultrasound and CT were more effective than PET in the differential diagnosis of hepatic tumor.FDG-PET showed a better accuracy in the diagnosis of intrahepatic cholangiocarcinomas, metastasis and rare primary hepatic carcinoma. AC-PET was a good complementary method to FDG-PET. Consideration of tumor size, amount, laboratory results and history could improve the diagnostic accuracy of PET and enhanced CT., Conclusion: PET must be combined with other image modalities to differentiate hepatic tumors more effectively and accurately.