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Background The elderly tend to coexist with multiple chronic diseases (such as diabetes and hypertension) , while diabetes and hypertension can lead to chronic kidney damage, and fewer studies have been conducted on chronic kidney disease in older adults. Objective To investigate the proteinuria and renal dysfunction in the elderly population and provide guidance for the management of chronic kidney disease in the community-dwelling older adults by collecting the clinical data of physical examination of the elderly residents in community. Methods A total of 13 080 elderly residents who underwent physical examination in Zhuanqiao Community Health Service Center of Minhang District, Shanghai from 2020 to 2021 were included as the study objects. General information, physical examination results and laboratory examination data of study objects were collected. Subjects with estimated glomerular filtration rate (eGFR)

This paper aims to observe the therapeutic effect of butylphthalide sodium chloride injection combined with urokinase in the treatment of acute ischemic stroke. A total of 60 patients with acute ischemic stroke were randomly divided into 2 groups: combined treatment group (butylphthalide sodium chloride injection + urokinase, N = 30) and control group (urokinase only, N = 30). National Institute of Health Stroke Scale (NIHSS) and Barthel Index (BI) were used to evaluate the improvement of neurological function and curative effect. Adverse reactions were also observed. As results, the markedly effective rate was 36.67% (11/30) and the total efficiency rate was 93.33% (28/30) in combined treatment group, while they were 10% (3/30) and 56.67% (17/30) in control group. There was significant difference between 2 groups ( χ2 = 13.195, P = 0.004). Besides, the neurological function of patients in 2 groups elevated to different degrees at each time point after treatment (P = 0.020). There was no significant difference in the incidence rate of adverse reactions between 2 groups (P = 0.572). The results indicated that the curative effect of butylphthalide sodium chloride injection combined with urokinase in the treatment of acute ischemic stroke is better than that of urokinase. doi: 10.3969/j.issn.1672-6731.2014.09.013