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Objective To explore the intervention effect of different exercise program on metabolic syndrome. Methods In the control of energy intake conditions, the patients with metabolic syndrome were divided into low intensity continuous exercise group (LCE); low intensity intermittent exercise group (LIE); medium intensity continuous exercise group (MCE);and medium intensity intermittent exercise group(MIE). The groups were given exercise program of 60 minutes one time, 5 times a week, a total of 12 weeks. The BMI, resting blood pressure, triglyceride(TG), high density lipoprotein cholesterol(HDL- C), fasting plasma glucose(FPG) index before and after the intervention were compared between two groups. Results Twelve weeks after exercise intervention, BMI,resting blood pressure, triglyceride(TG), high density lipoprotein cholesterol(HDL- C), fasting plasma glucose(FPG) were significantly improved in each groups(P <0.05) . The effect of moderate intensity exercise was significantly higher than that of low intensity exercise(P <0.05), and the effect of medium intensity intermittent exercise group(MIE) was significantly better than that of other groups(P <0.05) . Conclusions Medium or low strength intensity aerobatic exercise is an important non - drug way to control obesity and prevent metabolic syndrome. Intermittent medium intensity aerobic exercise is the best exercise way for prevention of metabolic syndrome. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effects of extremely low frequency electromagnetic field (ELF-EMF) on human osteosarcoma cells and its mechanisms., Methods: Human osteosarcoma MG-63 cells were exposed to 50 Hz,1 mT ELF-EMF for 1, 2 and 3 h in vitro, with or without pretreatment by reactive oxygen species (ROS) inhibitor N acetylcysteine (NAC) or p38MAPK inhibitor SB203580. The proliferation of MG-63 cells was determined by MTT method; the apoptosis rate and ROS level in MG-63 cells were detected by flow cytometry. The expression of p38MAPK in MG-63 cells was determined by Western blotting., Results: ELF-EMF decreased the viability of MG-63 cells, inhibited cell growth, induced cell apoptosis and increased the level of ROS significantly. The apoptosis rate declined significantly after treatment with ROS inhibitor NAC or p38MAPK inhibitor SB203580. After exposure to ELF-EMF, p38MAPK in MG-63 cells was activated, and the phosphorylation level was also inhibited after treatment with NAC., Conclusion: ELF-EMF can induce the apoptosis of MG-63 cells. Increased ROS and p38MAPK activation may be involved in the mechanism.