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An extreme heavy rainfall event struck the northern part of the Guilin urban area in the early morning of May 22, 2023, breaking local historical records for both hourly and three-hourly precipitation, resulting in severe urban waterlogging. Analysis was conducted using data from routine observation, ground-based dense automatic stations, Doppler weather radar, and ERA5 reanalysis. The results are as follows. (1) This event occurred on the edge of the subtropical high-pressure system, with the continuous strengthening of the southwest jet stream providing abundant moisture and energy for the extreme rainfall under the influence of the low-level shear line and the southward movement of the surface cold front. (2) The echoes of heavy rainfall evolved into a linear convection, which changed the direction and shape when timely met with the surface cold air. Meanwhile, the continuously developing new individual cells on its western side joined to form a "train effect," leading to extreme rainfall. The echo exhibited characteristics of low core and high efficiency. (3) The timely intrusion of weak cold air intensified convective rainfall and enhanced cold pool outflow, triggering new convection in the warm and moist region ahead of it, which favored the development and persistence of heavy rainfall. (4) During the eastward movement of individual convective cells, they merged through cloud bridges and expanded through cloud development, forming new cloud clusters and rapidly intensifying precipitation. The interaction and merging of convective cells were the main mechanisms for the prolonged and intensified heavy rainfall. (5) Various numerical models underestimated the intensity of this event, with biases in forecasting the rainfall center mainly due to deviations in the timing of forecasting the influence of surface cold air.

Objective To explore the relationship between the intraoperative plasma transfusion volume, the changes of blood coagulation test values and the clinical prognosis of surgical patients, so as to provide a theoretical basis for guiding the rational use of blood during the operation. Methods The clinical data of 556 surgical patients who received plasma infusion from January 2017 to December 2020 in Sun Yat-sen Memorial Hospital were collected. Patients were divided into low plasma dose group (

Objective To investigate the incidence of clinical massive blood transfusion in hospitals, the proportion of departments conducted massive blood transfusion and the current situation of component transfusion, so as to provide a theoretical basis for medical decision-making and further research on massive blood transfusion. Methods The basic clinical data and transfusion of blood components were retrospectively collected from 489 patients (514 occasions) who received massive blood transfusion at Sun Yat-sen Memorial Hospital of Sun Yat-sen University from Jan. 1 2014 to Dec. 31 2018. Results The incidence of massive blood transfusion during the 5-year period was 1.2/1 000 inpatients (95%CI: 1.1-1.3), and the 30-day all-cause mortality was 21.88%; in the departments where massive blood transfusion occurred, the mortality rate was the highest in the trauma emergency department (60%), followed by intensive care unit (56.25%) and other surgery department (46.67%), while there was no death in the obstetric department. All patients received red blood cells [median 14 U (11.5-19.13)] and plasma [median 1 600 mL (1 200-2 200)], of which 47% received platelet [median 0 U (0-10)] and 32.68% received cryoprecipitate [0 U (0-10)]. The results of logistics regression analysis of all-cause mortality risk showed that compared with the youth group, the risk of all-cause death at 30 days of elderly patients over 65 years old (65 < age ≤79 years old: OR=2.471, 95%CI=[1.044, 5.847], P 80 years old: OR=7.563, 95%CI=[1.587, 36.049], P

Objective:To examine the training and detraining effects of a group exercise activity program for the institutional residents with functional dependency.Method:Residents with functional dependency from two nursing homes (older than 60 years) were recruited.A total of 41 residents were randomly assigned to the intervention (n=18) or the control groups (n=23). The intervention group received group exercise three times per week for ten weeks, the control group maintained the original life style in the institute. Outcome measures included passive range of motion (PROM), muscle strength and upper extremity motor function. The measures were assessed at baseline (pre-test), after 11 weeks (post-test), and at 23 weeks follow-up.Result:At the end of the trial, the exercise subjects demonstrated significant improvement on ROM, muscle strength and upper extremity motor function over the control group (PP