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Takayasu's arteritis (TA) is a chronic granulomatous vasculitis mainly affecting the aorta and its major branches, which can cause stenosis, occlusion and aneurysm formation, severely influencing the affected women of childbearing age. TA has been extensively studied to be stable during pregnancy, but it may lead to pregnancy complications such as gestational hypertension, pre-eclampsia, preterm delivery, and intrauterine growth restriction. To reduce the adverse effects of TA on the mother and fetus, it is essential to control the disease activity during pregnancy. This article details the effects of TA on the reproductive system, its interaction with pregnancy and effects on the fetus, discusses the management measures during pregnancy and the perinatal period in patients of childbearing age with TA, providing guidance for improving multidisciplinary management and clinical outcomes in these patients.