Objective: To analyze the prevalence and variation of hypotension in Chinese adults residents in 2002 and 2010-2012., Methods: Data of the blood pressure measurements from 2002 and 2010-2012 China National Nutrition and Health Survey(CNNHS), a multistage stratified cluster random sampling survey was conducted in 2002, and the sample size was 147 488, 64 869 males, 82 619 females, 50 123 urban residents, 97 365 rural residents, 71 078 northern residents and 76 410 southern residents. A multi-stage stratified and population-proportional cluster random sampling method was used in 2010-2012, and the sample size of was 120 427, 52 499 males, 67 928 females, 60 214 urban residents, 60 213 rural residents, 53 863 northern residents and 66 564 southern residents. The population data published by the National Bureau of Statistics in 2009 was used as a standard population of the data result for 2002 and 2010-2012. Complex sampling weighting method was adopted in data analyses. The prevalence of hypotension and 95%CI in different populations were calculated. Chi-square test was used to compare the rates, multi-factor analysis was conducted by using SURVEYLOGISTIC model regression., Results: In 2002, the prevalence rate of hypotension in Chinese adults was 3. 0%, 1. 9% in males, 4. 1% in females, 2. 7% in urban residents, 3. 3% in rural residents, 2. 8% in northern residents and 3. 2% in southern residents. The prevalence rate of hypotension was the highest in 18-44 age group(4. 3%). Among people with different body mass index(BMI), the prevalence of hypotension was higher in low weight group(7. 0%). From 2010 to 2012, the prevalence rate of hypotension in Chinese adults was 2. 1%, 1. 1% in males, 3. 2% in females, 1. 9% in urban residents, 2. 2% in rural residents, 1. 8% in northern residents and 2. 3%in southern residents. The prevalence rate of hypotension was the highest in 18-44 age group(3. 1%). Among people with different BMI, the prevalence of hypotension was higher in low weight group(7. 4%). The total prevalence of hypotension in adult residents in China from 2010 to 2012 was lower than that in 2002, and the difference was statistically significant(χ~2= 624. 3, P <0. 0001). In 2002 and 2010-2012, the prevalence of hypotension in adult residents of China decreased with the increase of age, and the prevalence of hypotension in men and women also decreased with the increase of age. Women were higher than men, the lower age group was higher than the higher age group, and the lower weight group was higher than the normal population. The differences were statistically significant. Multivariate Logistic regression analysis also showed that lower age group, women and people with low weight were more prone to develop hypotension., Conclusion: In 2002 and 2010-2012, the total prevalence of hypotension in adult residents of China, and that of hypotension in both men and women decreased with the increase of age. Women were higher than men, the lower age group was higher than the higher age group, and the lower weight group was higher than the normal population. 18-44 age group, women and low weight group are more likely to have low blood pressure. Compared with 2002, the total prevalence of hypotension in Chinese adult residents showed a decreasing trend from 2010 to 2012.