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In order to meet the nursing needs of the elderly and disabled patients with mobility difficulties， a standing and lying nursing wheelchair that can assist standing and assisting lying is designed. The design scheme and working principle of the wheelchair mechanism are expounded. Based on the principle of ergonomics， three-dimensional gait analysis and motion system are used to analyze the movement trajectory of normal joints during the process of standing up and lying down. The geometric relationship between wheelchair mechanisms is established， and the kinematics analysis of the mechanism carried out. Combining the anthropometric data， the parameters of each component are determined and a virtual prototype is established. By using the Adams software， the motion simulation of the mechanism is carried out， the mechanism runs smoothly in the simulation. The simulation results show that the sitting， standing and lying nursing wheelchair assists the human body to sit， stand， and lie down in accordance with the laws of healthy human movement， which verifies the rationality of the mechanism design.

More available warning time and a quicker rapid intensity reporting after earthquake are of great significance to the earthquake early warning system and the after earthquake rescue. The improvement of the calculation speed of the instrument intensity and the accuracy of the calculation results are very important for the whole early warning process. The development of intensity in Japan has gone through three stages：instrument intensity of JMA in 1996，real-time instrument intensity in 2008 and real-time instrument intensity in 2013. This paper explains these three and gets the contract picture by using the data in the 2011 off the pacific coast of Tohoku earthquake. The instrument intensity using 2013 method is quicker than that using 1996 method，and the instrument intensity using 2013 method is closer to that using 1996 method，compared with that using 2008 method.