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Objective To investigate the outcome on 90 d and influencing factors for the outcome in conscious patients with intracerebral hemorrhage (ICH). Methods Two hundred and twenty-five patients with ICH were admitted to our hospital within 6 h after onset and were suitable to be treated with medical conservative therapy. Patients were divided into two groups, the conscious group [Glasgow Coma Scale (GCS) score ≥ 9] and the coma group (GCS score ≤ 8). Clinical features including gender, age, National Institute of Health Stroke Scale (NIHSS) score, etc, were recorded. The prognosis of these patients on 90 d after onset was evaluated by the following index: survival or death; favorable prognosis [modified Rankin Scale (mRS) score ≤ 2] or unfavorable prognosis (mRS score ≥ 3, death or severe disability). The difference of clinical features and prognosis between the conscious group and coma group was explored. The prognosis of the patients in conscious group was analyzed, and influencing factors for prognosis were explored. Results Multifactorial Logistic regression analysis indicated that hyperglycemia, higher NIHSS score, rehemorrhagia and hematemesis were independent risk factors for 90-day mortality. On the other hand, advanced age, higher NIHSS score, rehemorrhagia and hematemesis were independent risk factors for death or severe disability on 90-day. Conclusion In ICH patients who were conscious on admission, hyperglycemia, advanced age, higher NIHSS score, rehemorrhagia and hematemesis are strong predictors for mortality and unfavourable outcome. Controlling hyperglycemia and prevention of rehemorrhagia and hematemesis are important elements for reducing 90-day mortality and severe disability.

Objective: To understand the status of human hookworm ( Ancylostoma duodenale or Necator americanus ) infection in Jiangxi Province., Methods: A stratified cluster random sampling was conducted based on the geographical location and economic condition in 2014. Kato-Katz's thick smear method was used for stool examinations, and filter paper cultivation was conducted for distinguishing the species of hookworms., Results: A total of 21 615 persons were involved in the investigation, and there were 1 095 persons infected with hookworm with the prevalence of 5.07% (standardized rate of 4.05%). The infection rate of hookworm in Nanfeng County was the highest (13.96%). Most of the infected people had low worm burden (95.43%). The infection rate of hookworm of the female was higher than that of the male ( χ 2 = 28.03, P < 0.05). The prevalence increased with the age, while the infection rate of hookworm in people at ages of 75 years and higher was the highest (14.79%). Housewife was the highest risk occupation with the infection rate of 7.55%. The differences of infection rates among different educational level groups were significant ( χ 2 = 135.88, P < 0.05). The prevalence rates of hookworm in different landforms were significantly different ( χ 2 = 34.37, P < 0.05). The priority species was N. americanus (80.41%) in Jiangxi Province., Conclusions: The infection rate of hookworm decreases obviously in Jiangxi Province. The high risk groups of hookworm infection are the people with low educational level, female and elder age-group.

Objective: To discuss the clinical features of cerebral schistosomiasis., Methods: The clinical data of fourteen patients with cerebral schistosomiasis from March 2010 to March 2016 were collected and analyzed retrospectively., Results: The schistosomiasis immunological tests of sera and cerebrospinal fluids from the fourteen patients were all positive. Eosinophils increased in ten cases, and the proportion was 5.1%-60.3%. Schistosoma eggs were found in seven cases by the fecal Kato-Katz method. Fourteen cases were all infected with Schistosome japonicum . Twelve cases were diagnosed as chronic type, and two cases as acute type. Thirteen patients received medical treatment, of which twelve were cured, and one improved. One patient received the surgical resection of the lesion., Conclusions: The clinical manifestations of cerebral schistosomiasis mainly include seizure, headache, dizziness and fever. In the enhanced head magnetic resonance imaging (MRI), the lesions are clustered and merged into lumps, which is the characteristic image of cerebral schistosomiasis japonica. The praziquantel treatment can achieve a good prognosis.