Search

Because the traditional steam sootblowing technology has a dead corner, it needs a lot of high quality steam, and the safety of the steam is affected by the scouring of the heating surface. Therefore, in recent years, many new power plants tend to adopt built-in array acoustic sootblower in the low-temperature flue to purge the low-temperature reheater, low-temperature superheater and economizer. Combined with the application of acoustic sootblower in a 660 MW power plant, the economic evaluation was studied. The sootblowing economy was evaluated by two indexes:boiler efficiency at boiler side and steam turbine thermal efficiency at turbine side. The boiler anti-balance method was used to calculate the boiler efficiency variation when the exhaust gas temperature changed 1℃ under a certain load. The increase of boiler efficiency was calculated by the decrease of flue gas temperature after sootblowing, and the decrease of coal consumption was further calculated. By using the calculation method of heat carrying out system by working medium in the equivalent enthalpy drop method, the influence of sootblowing steam on the heat consumption of steam turbine was obtained, and the increase of coal consumption was further calculated. The economic gain of acoustic sootblower was obtained by considering the economic evaluation of boiler side and steam turbine side. The results show that compared with the conventional steam sootblower, the annual cost saving of the built-in array acoustic sootblower is more than 1 million yuan. In addition, it will have better energy-saving effect for units with poor economic performance for many years.

Objective To explore the effect of extracellular vesicles （EVs） secreted by steatotic hepatocytes on the activation of macrophages. Methods The nonalcoholic steatohepatitis （NASH） model was established by feeding SD rats with high-fat and high-cholesterol diet （HFHCD）. Hepatic lesions of rats were observed by HE, Oil Red O and Masson staining, and the activation of M1 macrophages in the liver was detected by immunofluorescent staining. HepG2 cells were induced to be steatotic hepatocytes with palmitic acid （PA）, and their secreted EVs were isolated by ultracentrifugation. Then the effect of EVs on macrophages was observed by co-culture experiments and corresponding indicators were analyzed by RT-qPCR and flow cytometry. Results The results of HE, Oil Red O and Masson staining showed that the NASH animal model was successfully established. Immunofluorescent staining confirmed that the proportion of CD68+CD86+ cells in the liver of HFHCD group was significantly increased （P < 0.05）. RT-qPCR showed that EVs in the PA group could up-regulate the expression of M1 macrophage markers （IL-1β, IL-18） （P < 0.001）. Flow cytometry demonstrated that EVs increased the proportion of CD86+ cells in the PA group （P < 0.001）. EV inhibitors （GW4869） could block this promoting effect. Conclusion Steatotic hepatocytes can aggravate NASH progression by promoting the activation of M1 macrophages via EVs.