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Background Somatosensory and motor dysfunctions are common after stroke, both lead to limitations in activities of daily living and social participation, there is still a lack of research evidence to analyze the relationship between the two from multiple perspectives. Objective To investigate the relationship between somatosensory and motor function among overall, upper and lower extremities in different-age-group patients within one year after stroke. Methods This prospective study enrolled the poststroke patients within one year from several hospitals in Fujian Province from October 2022 to April 2023. The sensory subscale of the Fugl-Meyer assessment (FMA-S) and the sensory subitem of National Institute of Health Stroke Scale (NIHSS) were used to evaluate the patient's somatosensory function. The motor subscale of the Fugl-Meyer assessment (FMA-M), Brunnstrom assessment, Berg Balance Scale (BBS) and the motor subitem of NIHSS were used to evaluate the patient's motor function. Modified Barthel Index (MBI) was used to evaluate the patient's activities of daily living (ADL). Hospital Anxiety and Depression Scale (HADS) was used to evaluate the patient's psychosomatic function. They were divided into two groups (the elderly group/the young and middle-aged group) according to their age, we compared the differences in general information and rehabilitation assessments between the two groups. And we analyzed the correlation between somatosensory function and motor function/ADL/psycho-psychological function. Results A total of 254 patients were included, with an average age of (61.0±12.3) years and an average disease course of 30.0 (17.0, 65.5) days. There were 112 cases (44.1%) in the elderly group and 142 cases (55.9%) in the young and middle-aged group. FMA-S and FMA-M scores were positively correlated in both groups (rs values were 0.313 and 0.171, both P

ObjectiveTo analyze the pathogenic characteristics of Salmonella senftenberg isolate causing food poisoning in Xinxiang in 2021.MethodsEpidemiological investigation of food poisoning event was performed. Pathogenic bacteria were separated and identified from 11 samples. Ten Salmonella isolates were subjected to serotyping， drug susceptibility testing， detection of characteristic gene fragments （mogA， sseL， mgtC， bcfA， araB） of 5 virulence island （SPIs） and pulsed field gel electrophoresis （PFGE） typing analysis.ResultsSerum antigenic formulas of all Salmonella isolates were 1，3，19；g，s，t Salmonella senftenberg. All Salmonella isolates were resistant to cefazolin， kanamycin， gentamicin and amikacin. Among them， two isolates from the patient feces were also resistant to ampicillin， tetracycline，doxycycline，chloramphenicol，trimethoprim/sulfamethoxazole. PFGE clustering analysis showed that there was no difference in the bands among the 10 strains （2 cases strains， 5 food strains， and 3 environmental strains）， suggesting that they were highly homologous. Five Salmonella pathogenicity island characteristic gene fragments were detected among 10 isolates.ConclusionSalmonella senftenberg caused the food poisoning event. The isolates carried 5 Salmonella pathogenicity island characteristic gene fragments and 2 isolates exhibited multi-drug resistance. Relevant departments should pay more attention to this issue.

A rapid and simultaneous lateral flow immunochromatography (LFIC) method was established based on colloidal gold (CG) for testing three addictive drugs in milk tea, including methamphetamine (MET), ketamine (KET), and cocaine (COC).After optimizing the key parameters, such as the concentration of coated antigen, the combination position of the three analytes, and the immunoreaction time, the developed method could be used for the simultaneous identification of three target addictive drays in a milk tea sample with a lower concentration could be tested.The limits of detection of MET, KET, and COC were 1.60, 1.59, and 1.39 ng/mL, respectively.In milk tea samples, the mean recoveries of the three types of mixed reference analytes ranged from 90% to 109% with a relative standard deviation of less than 5%.Briefly, the multiple CG-LFIC method had the advantages of easy operation, fast analysis, high sensitivity, and good specificity.It can be an effective method for simultaneous screening addictive drugs in milk tea and provides promising applications in the bio-detection field. [ABSTRACT FROM AUTHOR]