Search

Objective: To compare the clinic value between the transcervical resection of myoma (TCRM) and laparoscopic myomectomy (LM), and investigate the favourable surgical approaches in women with intramural uterine myomas. Methods: From January 1, 2007 to December 31, 2011, 236 women undergoing TCRM (hysteroscopy group) and 392 women undergoing LM (laparoscope group) were studied retrospectively in The Third Affiliated Hospital of Zhengzhou University. The patients' general information, peri -operative characteristics, postoperative muscle healing, and pregnancy outcome were compared and analyzed. Results: The average operation time, the average intraoperative blood loss and the reduce perioperative hemoglobin level of hysteroscopic group and laparoscopic group were compared respectively, the difference had statistical significance (P <0.05). The transfer laparotomy operation rate, postoperative fever rate and menstrual period rate of hysteroscopic group and laparoscopic group were compared. There was no significant difference (P>0.05). In the follow-up of 181 cases of hysteroscopy group and 336 cases of laparoscopic group of patients, the muscular complete healing rate of postoperative 1 month, 3 months, 6 months were respectively comparison, the difference had statistical significance (P<0.05). The muscular complete healing rate of postoperative 12 months was no statistically significant difference (P=0.709). The postoperative pregnancy from fibroids weed out of time for the first time of hysteroscopic group and laparoscopic group was statistically significant difference (P<0.05). All patients with postoperative pregnancy appeared no pregnant uterine rupture. Conclusions: For intramural myoma, two kinds of operation modes are safe and reliable. The intraoperative bleeding and postoperative recovery by TCRM is better than the patientes treated by LM, so hysteroscopy surgery is superior to the laparoscopic surgery for the patients with intramural uterine myoma. [ABSTRACT FROM AUTHOR]

Anions are ubiquitously distributed not only in biological systems but also in environment. Accordingly, anion recognition and sensing have attracted increasing attention due to the important roles anion plays in biological, chemical and environmental fields. Among various anionic species, NO3- is a very important inorganic anions which has a great harm to the environment and human health. At present, methods for the determination of NO3- mainly contained electrochemical method, ion chromatography and ion selective electrode method. Although all methods have their own advantages, but also has the obvious deficiency. Such as, the reproducibility of electrochemical method is not good, and ion chromatography and ion selective electrode method usually require expensive apparatus and lengthy analytical time. As a contrast, fluorescence spectroscopy become a hot research topic in anion recognition and detection because of its high sensitivity and easy operation and other advantages in recent years. New bipyridinium salt L was designed and synthesized using pyrylium as a starting material. The molecular structure was determined by 1H NMR, 13C NMR, and high resolution mass spectrometry. The molecular recognition properties of L have been investigated through fluorescence titration experiments. The results indicate that L has sensitive and selective fluorescent response to NO3- among other different anions. Significant enhancements in the fluorescence intensity of L were observed when various concentrations of NO3- were added, while other competing anions have a quenching effect towards the initial fluorescence of solution. The fluorescence titration spectra shows that the bonding stoichiometry between receptor L and NO3- is 1 : 1 as a supramolecular complexes (1gK = 5 ± 0.02). The chemosensing properties of L were evaluated through quantum chemical calculations and the variable temperature 1H NMR titration. These results suggested that L has strong binding affinity towards NO3- with high selectivity, which may be ascribed to the specific hydrogen bonding between the L and active H atom of the bipyrydinium salts. The interaction between L and NO3- made the complex more planar compared with L giving rise to enhanced fluorescence and specific selectivity towards NO3-.