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Objective To investigate the difference of multimodal ultrasound parameters between thyroid carcinoma and benign thyroid nodules in imaging and the independent risk factors of malignant nodules. Methods Sixty patients with thyroid carcinoma who underwent surgical treatment and confirmed by postoperative pathology in Baoding No.2 Central Hospital from January 2020 to December 2022 were retrospectively selected as the malignant group, and sixty patients with benign thyroid nodules during the same period were selected as the nodule group. Conventional ultrasound signs, contrast-enhanced ultrasound (CEUS) signs, and shear wave elastography (SWE) signs were compared between the two groups, and a multivariate logistic regression analysis was performed to identify independent risk factors for thyroid malignant nodules. Results There were significant differences in nodule morphology, echo, composition, aspect ratio, boundary, calcification, cervical lymph node characteristics and blood flow of conventional ultrasound signs between the two groups (P＜0.05). There were significant differences in enhancement pattern, enhancement boundary, enhancement level, enhancement uniformity, enhancement mode and exit mode of CEUS between two groups (P＜0.05). The maximum and average values of SWE Young's modulus in the longitudinal and transverse sections of the malignant group were higher than those of the nodule group (P＜0.05). There was statistical difference in SWE image classification between the two groups (P＜0.05). Logistic regression analysis showed that conventiona ultrasound signs micro-calcification (OR=6.435, 95% CI: 4.115-10.063), CEUS centripetal enhancement (OR=5.257, 95%CI:2.857-9.674), and higher SWE Young's modulus longitudinal maximum value (OR=5.120, 95% CI： 3.026-8.663) were independent risk factors for malignant nodules (P＜0.05). Conclusion Conventional ultrasound signs micro-calcification, CEVS enhanced centrality and high maximum profile of SWE Young's modulus are independent ultrasonic risk factors of thyroid nodules. The combined application of ultrasonic multimode is expected to further improve the accuracy of qualitative diagnosis of thyroid nodules.

Objective: To explore and study the correlation between high-risk pregnant women and fetal hypoxia and color Doppler ultrasound combined with four-dimensional ultrasound. Methods: February 2018 to January 2020, 108 cases of high-risk pregnant women who were filed deliveries in our hospital were selected. All the cases were all given color Doppler ultrasound combined with four-dimensional ultrasound, recorded the imaging characteristics and determined the occurrence of fetal hypoxia. And carried out correlation analysis. Results: There were 28 cases of intrauterine hypoxia occurred (intrauterine hypoxia group) in the 108 cases, the incidence were 25.9 %. The resistance index (RI), pulsation index (PI), the peak systolic flow velocity and the diastolic flow velocity ratio (S/D) of the middle cerebral artery and the umbilical artery in the intrauterine hypoxia group were higher than those of the non-intrauterine hypoxia group(P<0.05). The superior vena cava blood flow ventricular systolic peak velocity (S wave), atrial systolic velocity (a wave) and ventricular diastolic peak flow velocity (D wave) in the intrauterine hypoxia group were higher than those in the non-intrauterine hypoxia group (P<0.05). In the 108 high-risk pregnant women, Spearsman analysis showed that the RI, PI, S/D of the middle cerebral artery and umbilical artery, blood flow S, D, A of the superior vena cava were correlated with the intrauterine hypoxia (P<0.05). The logistic multivariate regression analysis showed that the S/D of the middle cerebral artery and the umbilical artery and the blood flow of the superior vena cava S and A were the main influencing factors of fetal hypoxia (P<0.05). Conclusion: Fetal hypoxia in high-risk pregnant women are correlated with the characteristics of color Doppler ultrasound combined with four-dimensional ultrasound. Color Doppler ultrasound combined with four-dimensional ultrasound can be feasible, simple, non-invasive, convenient and quick way to detect fetal hypoxia, and have very good application values. [ABSTRACT FROM AUTHOR]

Objective To explore the diagnostic efficacy of breast ultrasound signs for atypical invasive ductal carcinoma. Methods Through surgical pathological diagnosis, 34 invasive ductal carcinoma nodules(observation group) and 38 benign breast tumors(control group)were selected. The ultrasound examination signs of the two groups were compared. The single-factor statistically different indicators were incorporated into the Logistic regression model for multivariate analysis, the Logistic regression model was established, and the ROC curve was drawn to evaluate the diagnostic value of the model for atypical invasive ductal carcinoma. Results Univariate analysis showed that significant differences were found between these two groups in the following aspects: aspect ratio≥1, uneven internal echo, RI>0. 70, tumor enhancement method after contrast, late enhancement degree, unclear boundary, uneven distribution of contrast agent, range expansion, and nourishing blood vessels. Multivariate analysis showed that uneven internal echo, RI>0. 70, concentricity enhancement, and range expansion were risk factors for the diagnosis of atypical invasive ductal carcinoma. We established a diagnostic model based on the above risk factors: Logistic(P)= -4. 225 + 2. 676(uneven echo)+ 2. 865(RI> 0. 70)+ 3. 968(concentricity enhancement)+ 3. 712(range expansion). The cut-off value of this model for the diagnosis of atypical invasive ductal carcinoma was 0. 436, the AUC was 0. 965(0. 892-0. 994), the sensitivity was 88. 24%, and the specificity was 89. 47%, respectively. Conclusion The Logistic regression model established by the four ultrasound signs of uneven internal echo, RI> 0. 70, concentricity enhancement, and range expansion has a high accuracy in diagnosing atypical invasive ductal carcinoma. [ABSTRACT FROM AUTHOR]

The aim of this paper was to investigate the value of transvaginal color Doppler ultrasonography (TVCDU), three- dimensional color power angiography (3D-CPA) combed with pulse wave Doppler (PW) m the differential diagnosis of ovarian space-occupying lesions and the evaluation of preoperative staging of magnet lesions. There were 110 patients with ovarian space- occupying lesions who were selected and examined by color Doppler ultrasound, among whom 49 cases were malignant, 61 cases were benign. The peak systolic velocity (PSV) and vascular index (VI) of malignant tumors were significantly higher than those of benign tumors (P$0. 05), white resistance index (RI) was significantly lower than that of benign tumors (P$0. 05). The proportion of vascular grade ( of malignant tumors was significantly higher than that of benign tumors (P$0. 05), while the proportion of grade I was significantly less than that of benign tumors (P$0. 05). The proportion of VI and vascular grade ( in stage ( patients was significantly higher than that of patients I II (P<0. 05). The area under ROC curve of RI, VI, vascular classification and combined diagnosis on malignant tumor were 0. 794, 0. 774, 0. 937 and 0. 966, respectively. The area under the ROC curve of VI, vascular grading and combined diagnosis of malignant tumor FIGO stage ( were 0. 810, 0. 691 and 0. 955. In conclusion, TVCDU and 3I-CPA combined with PW have good application value in differentiating the nature of ovarian mass lesions and preoperative staging assessment of malignant lesions. [ABSTRACT FROM AUTHOR]

Objective: To investigate the influence of lienal polypeptide injection on ultrasound and serum levels of AFP in patients with primary liver cancer. Methods: 168 patients with primary liver cancer who were treated in our hospital were selected and divided into the control group and the experiment group, with 84 cases in each group. The patients m the control group were treated with transcatheter arterial ehemoembolization (TACE), while the patients in the experiment group were treated with lienal polypeptide injection on the basis of the control group. Then the tumor blood supply, serum tumor marker levels, peripheral blood immune cell levels, the clinical effect and the incidence of adverse reactions in the two groups were observed and compared before and after the treatment. Results: The effective rate m the experiment group was higher than that of the control group, and the difference was statistically significant (P<0.05); Compared with the control group, the blood flow classification levels of intra tumor artery and peripheral tumor artery were lower, blood flow classification level of tumor peripheral portal vein was higher, serum levels of AFP, CA19-9, GGT and AFU were lower, peripheral blood NK cell, CD4+T lymphocyte and CD4+/CD8+ ratio levels were higher, and CD8+T lymphocyte level was lower in the experiment group after treatment (P<0.05); The incidence of adverse reactions mcluding the nausea and vomiting, loss of appetite, leukopenia, fever and fatigue m the experiment group was lower than that of the control group (P<0.05). Conclusion: Lienal polypeptide injection can significantly reduce the blood supply of tumor tissue in patients with primary liver cancer, reduce the levels of AFP, CA19-9, GGT, AFU, reduce the inhibitory on immune functions, unprove the clinical effect, and reduce the incidence of adverse reactions. [ABSTRACT FROM AUTHOR]

Objective: To research the diagnostic value of transvaginal color Doppler ultrasound in gynecological pelvic tumors with obturator lymph node metastasis. Methods: A total of 86 patients with gynecological pelvic tumors, who underwent hysterectomy plus pelvic lymphadenectomy in Southwest Hospital of Third Military Medical University of PLA from January 2013 to December 2014, were chosen as the subjects and randomly divided into observation group (n=43) and control group (n=43) according to the order of the surgery. The observation group was detected by transvaginal color Doppler ultrasound to know if the patients had obturator lymph node metastasis; the control group, by B-ultrasound. The accuracy of detection was compared between the two groups. Results: The test results of the patients in the observation group showed that 14 cases had transfer, 29 cases hadn't transfer, there was no statistically significant difference compared with pathological findings (P <0.05). The test results of the patients in the control group showed that 5 cases had transfer, 36 cases hadn't transfer, there was statistically significant difference compared with pathological findings (P> 0.05). The accuracy rate of the observation group was 95.3%, while the accuracy rate of the control group was 81.4%, there was statistically significant difference between the two groups (u=4.0737, P=0.0436). The satisfaction rate of the observation group was 90.7% after the detection,while the satisfaction rate of the control group was 79.1%, there was statistically significant difference between the two groups (U=2.7051,P=0.0068). Conclusions: The transvaginal color doppler ultrasound has a high accuracy in the diagnosis of patients with gynecological pelvic tumor and obturator lymph node metastases, which is worthy of clinical reference. [ABSTRACT FROM AUTHOR]

Objective: To assess three-dimensional echocardiographic application value of different ages and gender on bicuspid aortic valve malformation (BAV). Methods: Echocardiography in our hospital from June 2012 to September 2014 detected 70 cases of BAV patients, which were divided into 4 groups according to the age, ≤20 age group 7 cases, 21-40 age group 14 cases, 41-60 age group 30 cases, and ≥60 age group 19 cases; which were divided into 2 groups, 42 cases in male, 28 cases in female according to the gender. Measurement of different cases on internal diameter and of Aortic sinus and ascending aorta, interventricular septum thickness, left ventricular function and left atrial diameter, four complication rates were compared with aortic stenosis, regurgitation, calcification and prolapse. Results: In cardiac structure, age groups on interventricular septal thickness in ≥60 age group 12.37±1.64 mm is higher than ≤20 age group 10.43±2.22 mm and 21-40 age group 11.00±1.92 mm; left atrial diameter in 41-60 age group 38.73±7.95 mm and ≥60 age group 40.05±9.71 mm are higher than ≤20 age group 29.86±1.86 mm. Gender groups on left ventricular function in female 64.18±6.04% is greater than male 58.71±11.28%. In complication rates, age groups on aortic stenosis in 41-60 age group 80%, ≥60 age group 84% are higher than 21-40 age group 50%, gender groups on stenosis in male 81% is greater than female 54%, regurgitation in female 79% is greater than male 50%. Conclusion: Three dimensional echocardiography in the diagnosis of BAV can obtain more comprehensive and specific, intuitive diagnostic information, ultrasonography in patients with BAV is closely related to the age and gender. [ABSTRACT FROM AUTHOR]

Objective To deeply recognize the knowledge of rare acute abdomen of primary peritonitis in children．In order to develop the diagnostic ability of ultrasound， we investigated the ultrasonographic characteristics of primary peritonitis and induce main points of differential diagnosis．Methods Patients with the abdominal pain，abdominal distension，vomiting and patients with fever from November 2008 to November 2014 were received ultrasound examination．In the end， there were 23 patients entering the investigation．The symptoms， positive physical examination， laboratory examination results， the other imaging manifestations， treatment and curative effect of the patients were recorded so as to emphasize the ultrasonographic features and main points of differential diagnosis．Results （1） Of the 23 patients，the ratio of male to female was 4：19．The patients’ages were 41 days～9 years and 11 months and the mean duration between the onset of the disease and making right diagnosis was 2 days ～9 days； （2） The commonest complains and physio-chemical examination results were abdominal pain， abdominal distension， leukocytes of perpheral blood elevation and neutrophils elevation； （3） All patients receiving ultrasound examination and mesenteric thickening and more powerful echo were observed only in 91.3％ （21/23） of them．Abdominal cavity effusion in 82.6% （19/23）， mesenteric lymphadenectasis in 60.1% （14/23），abdominal part of intestinal wall thickening and intestinal effusion in 56.5% （13/23） was observed； （4） At the same time， CT scanning showed intestinal effusion in 39.1% （9/23） of children patient．Conclusion （1） Primary peritonitis in children is a very rare disease and it has no specific manifestation．It is difficult to diagnose before surgery； （2） The disease is characterized by mesenteric thickening，abdominal cavity effusion and so on．Ultrasound is the evaluation of diagnostic information； （3） The ultrasonographic features will be identified of primary peritonitis with secondary peritonitis or tuberculous peritonitis in diagnosing； （4） So the sensitivity of ultrasound is higher than the detection of CT in primary peritonitis． [ABSTRACT FROM AUTHOR]

Objective To explore the characteristics of two dimensional and color Doppler ultrasonic examination in the diagnosis of multi-Takayasu arteritis. Method Color Doppler ultrasonic images of the peripheral vascular and heart were retrospectively analyzed in 14 cases with multi-Takayasu arteritis proved by clinical manifestation. Results (1) The ultrasonic characteristics of the lesions were listed as diffused thickening of intima-media (IMT), low-echo and stenosis or occlusion of the involved vessels, clear demarcation between lesion segments and non-lesion ones, the respective changes of the blood rheology revealed by the color Doppler. (2) The increasement of the affected heart chamber, thickening and motion abatement of ventricular walls, abatement of left ventricular diastolic and systolic function. Conclusion The color Doppler ultrasound can reveal lesion characteristics, extent and degree of cases with this disease accurately and visually in real time, is the first choice for diagnosis of multi-Takayasu arthritis in clinic. [ABSTRACT FROM AUTHOR]