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Copyright of Food & Fermentation Industries is the property of Food & Fermentation Industries and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

为了开发降血脂食品，以沙棘籽油、亚麻籽油为主要原料，并以天然维生素E、明胶、纯净水、甘油等为辅料制成沙棘亚麻籽油软胶囊，以雄性SD大鼠为实验动物，对沙棘亚麻籽油软胶囊的降血脂功能进行评价，再通过小鼠急性经口毒性实验、遗传毒性实验和大鼠30 d喂养实验对其毒理性进行评价，并选择110例符合纳入标准的高脂血症患者，连续服用沙棘亚麻籽油软胶囊45 d后测定相应指标，评价其对人体的降血脂功能和安全性。结果表明：高剂量组(0.667 g/kg)大鼠血清中TC、TG和LDL-C含量分别平均下降了15.6%、22.3%、29.0%，与模型对照组相比均差异极显著(p

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)