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The pathologies of parathyroid glands are widespread among endocrine system diseases, excluding diabetes and thyroid pathology. There are only two methods that are used to treat hyperparathyroidisms, such as surgery and conservative therapy. However, transracial thermal destruction methods (ablation) have recently appeared in clinical practice. The methods have good precision and connect with physical phenomena, such as interaction laser, radiofrequency, microwave, and HIFU irradiation with bio substance. The review is dedicated to critically analyze the modern methods for local thermal destruction of the hyper-functioning parathyroid glands. The review includes data from randomized clinical trials from 2012 to 2021. The studies were from Google Scholar and Pubmed with a total number of 1,938 patients (laser ablation ― 216 patients, radiofrequency ablation ― 225, microwave ablation ― 1467, high-density ultrasound ablation ― 30 patients). Recommendations methods of thermal destruction application were obtained during the review. Furthermore, we have designed some algorithms for hyperparathyroidism treatment. Moreover, thermal destruction methods were observed. There are four modern methods of thermal destruction which have been analyzed like alternatives to surgery. Each of them has advantages and disadvantages, its profile of safety and effectiveness. After processing information from a proven database, the most popular among specialists is methods of microwave ablation. However, laser ablation is more effective than other ways.

Poly (ether ether ketone)(PEEK) was synthesized via polycondensation of hydroquinone with 4, 4'-difluorobenzophenone at 320℃ for 5 h.Thermal and thermo-oxidative degradation of PEEK was studied over a wide range of temperatures.In an inert medium, decomposition of the polymer occurred in one stage, with the formation of a coke residue accounting for approximately 50% of the original polymer mass.In air, the mass loss curve exhibited two distinct stages.The first stage involved breakdown of the main polymer chain, the speed of which indicated a radical chain failure mechanism.In the second stage, the rate of mass loss clearly decreased, indicating a transition from the radical chain failure mechanism to simple combustion reactions (wherein the polymer combusted completely).To further investigate the nature of the processes occurring during the pyrolysis of PEEK, the investigations were carried out using gas chromatograph under isothermal conditions.It was concluded that during thermal degradation, the decomposition of the polymer starts with the rupture of ketone and ether bonds and proceeds to destruction of the benzene ring at higher temperatures, which is accompanied by the formation of H 2 O and CH 4 .Above 500℃, the polymer degradation further involved thermohydrolysis.The thermo-oxidation of PEEK, which was accompanied mainly by the formation of CO 2 and H 2 , was noticeable beginning at 325℃.The total yield of the latter indicated oxidation of fragments of the benzene ring.