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Function and integrity disorders of the oral cavity fall into the most frequent complication of the chemotherapy of leucemias, malignant lymphomas and solid tumors. Complications associated with cancer chemotherapy can be direct ones, resulting from the toxic action of antineoplastic agents on the proliferative lining of the mouth, or indirect, as a result of myelosuppression and immunosuppression. The most frequent oral complications associated with cancer chemotherapy are mucositis, infection and bleeding. The principles of prevention and management of oral complications during cancer chemotherapy are considered in this paper.

The aim of the investigation is to evaluate the dependence of the most frequent postextraction complications (pain, hemorrhage, hematoma, swelling and dry socket) in relation to the choice of anesthesia. The total of 447 teeth was extracted in 319 male and female persons between 11 and 80 years of age. The most important conclusion of the investigations is that vasoconstrictor in local anesthetic solutions does not influence the incidence of postextraction complications. Clot disturbance, higher incidence of dry socket and unpredicted time of pain appearance were found in the local anesthetic group with lower concentration of vasoconstrictor. Statistically significant difference between local and general anesthesia does not exist in relation to blood clot disturbances, although a great number of clot fails is evident in local anesthetic group. The pain intensity is lower when teeth extraction were performed under general anesthesia.