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Gouveia R, Cibula D, Soukup V, Hanuš T. Melanoma of the female urethra. Melanoma of the urethra, or melanomas originating from the gynecological tract, are extremely rare and aggressive malignant tumors, with high metastatic potential and a poor prognosis, affecting almost exclusively elder female patients. The aim of this case report is to present the case of a patient with urethral and bladder melanoma metastasis from a previously treated primary melanoma of the vulva. Radical cystourethrectomy and Bricker-Nesbit ureteroileostomy and bilateral extended pelvic lymphadenectomy were performed. Histology report confirmed melanoma invading the urethra and bladder, all removed lymphatic nodes were negative. On the 6-month follow-up PET-CT there was no evidence of residual disease. We concluded that in the presence of such a suspicious urethral lesion, prompt diagnosis to differentiate from other benign lesions and early radical management with careful post-operative follow-up schedules should be the standard treatment. [ABSTRACT FROM AUTHOR]

We present a review of the classifi cation of penile intraepithelial neoplasias preceding invasive squamous cell carcinomas. Since these lesions are analogous to vulvar lesions, we present classification of vulvar lesions, and discuss the analogy between vulvar and penile intraepithelial neoplasia classification. Terms such as Bowenoid papulosis, Bowenoid dermatosis, erythroplasia of Queyrat, leukoplakia, and giant condyloma of Buschke-Lowenstein should not be used in diagnostic pathology. [ABSTRACT FROM AUTHOR]