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Some differences exist in the diagnosis and therapy of bladder outflow obstruction between the general population and patients with end stage renal disease. They include, but are not limited to, variability in the degree of residual diuresis, altered bladder sensation, end stage renal disease-induced changes in urodynamic parameters, and differences in circadian diuresis. Understanding and recognizing these differences, as well as their implications in diagnostic and therapeutic procedures, including optimal timing of diagnosis and treatment, within this group of patients, will lead to better treatment outcomes and a lower rate of complications. [ABSTRACT FROM AUTHOR]