1. Galektin-3: kardiologická problematika.
- Author
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Jabor, A. and Franeková, J.
- Subjects
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NATRIURETIC peptides , *HEART transplantation , *GALECTINS , *HEART diseases , *HEART fibrosis , *CHOLESTERYL ester transfer protein - Abstract
Galectin-3 is mainly used in cardiology as a prognostic marker. Its pathophysiological effects correlate with the risk of cardiac fibrosis and remodelation. Elevated concentrations of galectin-3 in plasma (above the decision limit of 18 µg/L) increase the risk of cardiovascular morbidity and overall mortality, especially in patients with heart failure, myocardial infarction, heart transplantation and other cardiac diseases. The predictive value of galectin-3 increases when combined with natriuretic peptides. In cardiology, galectin-3 is recognized as a candidate molecule for prognostication. [ABSTRACT FROM AUTHOR]
- Published
- 2022