1. [Autoimmune synaptic encephalitis is a disease entity on the rise].
- Author
-
Modvig S, Høi-Hansen CE, Uldall P, and Somnier F
- Subjects
- Adolescent, Adult, Animals, Autoantibodies metabolism, Child, Female, Fluorescent Antibody Technique, Indirect, Humans, Male, Mental Disorders etiology, Prognosis, Rats, Receptors, GABA-B genetics, Receptors, N-Methyl-D-Aspartate genetics, Autoimmune Diseases of the Nervous System diagnosis, Autoimmune Diseases of the Nervous System immunology, Autoimmune Diseases of the Nervous System physiopathology, Autoimmune Diseases of the Nervous System therapy, Encephalitis diagnosis, Encephalitis immunology, Encephalitis physiopathology, Encephalitis therapy, Synapses immunology, Synapses physiology
- Abstract
The term autoimmune synaptic encephalitis (ASE) comprises encephalitides associated with autoantibodies against structures of the neuronal synapse. We review four types of ASE (anti-N-methyl-D-aspartate receptor encephalitis, anti-α-amine-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor encephalitis, anti-gamma-aminobutyric acid receptor 1 encephalitis and anti-leucine-rich glioma-inactivated 1 encephalitis) including their epidemiology, clinical characteristics and treatment.
- Published
- 2012