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This article shows how companies can circumvent competition legislation by developing new informal ways of cooperation. We focus on the case of the Nordic pulp and paper industry which was particularly eager to set up cartels. Scholars analysing this sector can utilise exceptionally rich sources that reveal how industrialists reacted to the introduction and development of European competition policies. The article shows that companies defended their collusive practices by making them less transparent and more informal than before, a change that did not automatically lessen their effectiveness. Tougher competition policies also encouraged industrialists to create new giant companies. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic has changed life in Europe and globally. The pandemic affects both individuals and the broader society across many domains, including physical and psychological health, the economy and general welfare. The measures taken to counteract the pandemic have significantly altered daily life and, along with the threat of contracting the coronavirus and uncertainties surrounding future developments, created a complex system of stressors with a negative impact on public mental health. This paper aims to outline the ESTSS strategy to address mental health issues related to COVID-19 and focuses on (1) trauma-informed policies, (2) capacity building, (3) collaborative research and (4) knowledge-exchange. To facilitate implementation of a trauma-informed approach and appropriate measures, ESTSS has developed a toolkit of recommendations on mental health and psychosocial assistance to be provided during the different phases of crisis and its aftermath. To promote capacity building, ESTSS offers a certification programme based on a curriculum in psychotraumatology and corresponding on-line training to the European community of mental health professionals. To assure evidence-based approaches and methods tailored to current circumstances, ESTSS has initiated a pan-European research project with international cooperation aimed at studying the mental health consequences of the pandemic, with a focus on psychological trauma and other stress-related reactions. To foster knowledge-exchange, the European Journal of Psychotraumatology (EJPT), the official journal of ESTSS, is publishing a special issue on COVID-19. [ABSTRACT FROM AUTHOR]

This paper shares an early-career perspective on potential themes for the upcoming International Association of Hydrological Sciences (IAHS) Scientific Decade (SD). This opinion paper synthesizes six discussion sessions in western Europe identifying three themes that all offer a different perspective on the hydrological threats the world faces and could serve to direct the broader hydrological community: "Tipping points and thresholds in hydrology," "Intensification of the water cycle," and "Water services under pressure." Additionally, four trends were distinguished concerning the way in which hydrological research is conducted: big data, bridging science and practice, open science, and inter- and multidisciplinarity. These themes and trends will provide valuable input for future discussions on the theme for the next IAHS SD. We encourage other early-career scientists to voice their opinion by organizing their own discussion sessions and commenting on this paper to make this initiative grow from a regional initiative to a global movement. [ABSTRACT FROM AUTHOR]

The permanent changes in society affect, among other, the environment. This is why environmental efficiency plays a very important role, being quantified in different forms. In our paper we have developed a composite index of ecological efficiency taking into account two dimensions, environmental pollution and resource consumption, each one being characterized by specific indicators. Thus, using this index, the aim was to evaluate and rank the level of greening of each country in Europe. Crises over time, including the health crisis caused by coronavirus, have focused to resilience, so we have highlighted whether it is significantly influenced by the ecological efficiency index. In addition, we analyzed whether ecological efficiency is related to investments in a country, financial, material and technological potential. [ABSTRACT FROM AUTHOR]

Distributional implications of capital account regulation is eminently context-specific. This paper examines the distributional effects of the openness of foreign direct investment (FDI) flows across 27 European countries in different economic environments around the Great Recession, covering the period 2007–2013. Our multi-level approach allows us to combine country-level variables and sociodemographic characteristics of individuals. The results highlight that the openness of FDI flows heterogeneously affects the income share of individual groups, favouring in particular the highest income classes. This finding seems to be driven by the educational level. We argue that even though highly educated individuals are present along the entire distribution, the highest income classes are especially favoured by the openness of FDI flows. This biased distributional effect of the openness of FDI flows persists throughout the years examined, regardless of the economic environment; this is due, in part, to the fact that the distribution of highly educated people is not sensitive to the business cycle. [ABSTRACT FROM AUTHOR]

The EU COST Action 15111 collaboration on myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) aims to assess current research and identify knowledge gaps in Europe. Presently, our purpose is to map the effects of non-pharmacological therapies (NPTs) for ME/CFS, and what patients find important in the treatment process. A scoping mixed methods literature review of European studies identified 16 papers fulfiling our inclusion criteria. The quantitative and qualitative studies were synthesized separately in tables. Additionally, extracts from the qualitative studies were subjected to translational analysis. Effect studies addressed cognitive behavioural therapy (CBT, n = 4), multimodal rehabilitation (n = 2) and activity-pacing (n = 2). CBT reduced fatigue scores more than usual care or waiting list controls. The effects of rehabilitation and activity-pacing were inconsistent. The contents, assessment methods and effects of rehabilitation and activity pacing studies varied. For patients, health professionals' recognition of ME/CFS and support were crucial, but they expressed ambiguous experiences of what the NPTs entail. Methodological differences make comparisons across NPTs impossible, and from a patient perspective the relevance of the specific contents of NPTs are unclear. Future well-designed studies should focus on developing NPTs tailored to patients' concerns and evaluation tools reflecting what is essential for patients. [ABSTRACT FROM AUTHOR]

Youth in the post-Soviet countries have faced the challenges of identity formation in concomitance with the processes of state-building in newly independent states. This paper focuses on young people aged 14 to 19 in seemingly different post-Soviet countries, Georgia and Latvia, who grew up after the collapse of the Soviet Union in independent countries striving towards Europe and its values. Based on qualitative interviews conducted in schools for the <#funding-source;>Horizon 2020 CHIEF project, the paper discusses some aspects of young people's identity formation, and how they see themselves in national and European contexts. Along with some similarities evident in both countries, such as young people reporting a very strong sense of national belonging and identity, the data also show important differences when it comes to young people's perceptions of Europe in Latvia and Georgia, as the latter report some reluctance in regards to accepting European identity and values. [ABSTRACT FROM AUTHOR]

Black kites of the nominal subspecies Milvus migrans migrans breed in Europe and winter regularly in sub-Saharan Africa and the Middle East. As a new phenomenon, black kites with morphological characteristics of the subspecies Milvus migrans lineatus are observed in Europe. Based on observations of black kites in winter 2020/2021 summarized in this paper, based on other recent reports about wintering black kites in Europe and based on juvenile black kite tagged on Crete and tracked for two years, we conclude that hundreds to thousands of black kites are now regularly wintering in south of Europe, and in smaller numbers in other parts of Europe as well as in northern Africa. The growing number of wintering black kites in Europe is apparently caused by members of the population from a hybrid zone between M. m. migrans and M. m. lineatus breeding east of the Urals, i.e. from the area of the European part of Russia. This is consistent with the hypothesis of the spreading of M. m. lineatus and a subsequent hybridization zone between M. m. migrans and M. m. lineatus in a westerly direction from Siberia across continental Europe. Moreover, two black kites found dead on Crete were attributed to M. m. lineatus and M. m. migrans by cytochrome B gene sequence analyses. The juvenile black kite with lineatus features tagged on Crete and telemetrically tracked during the next two years moved to the south-western part of Russia during the next two summers, but did not breed. It spent the following two winters at the same landfill in south-western Turkey. It seems that an adaptation to food sources provided by municipal waste landfills is important for black kites wintering in Europe, the Middle East and Morocco. Highlights • Hundreds to thousands of black kites are now regularly wintering in Europe. • The growing number of wintering black kites is caused by birds from a hybrid zone between Milvus migrans migrans and M. m. lineatus in eastern Europe. • Municipal waste landfills are important as food sources for black kites wintering in Europe. [ABSTRACT FROM AUTHOR]

Animal welfare protection is a challenge for which policy-makers are demanding scientific-based evidence. Considering horses, the challenge is even greater, as their role in society varies from production to companion animals. This review aimed to describe the evolution and geographical distribution of horse welfare literature over the years, to identify the most studied research topics and to highlight the still present gaps in knowledge. A search on Scopus® bibliometric database was performed using different welfare-related keywords. Predetermined filters were posed on time range, language and subject area. A total of 6584 records were downloaded and screened retaining only the ones dealing with horse welfare and behavioural sciences. Descriptive statistics, text mining (TM) and topic analysis (TA) were performed on the abstract of 801 eligible records. The results showed the number of studies on horse welfare is exponentially increasing, especially in the European continent. 'Transport' was the most frequent word, but also 'behaviour' and 'pain' emerged. Nine topics were identified and covered different subject areas: stress analysis, pain assessment, equitation science, human–horse interactions, breeding management, transport, working equids and health. The evaluation of stress and pain, horse social behaviour and the human–horse relationship resulted to be the most studied aspects related to animal welfare. On the contrary, the concept of positive welfare and the welfare assessment at slaughter of horses were underrepresented, confirming the limited literature on these subjects. This review confirmed the growing impact of research on horse welfare and highlighted how some important areas still do not provide sufficient scientific evidence. Analysis of the literature related to horse welfare was performed using text analysis techniques to identify trends in words and research topics. Results showed that the literature on horse welfare has exponentially grown in the last 43 years, especially in Europe. The most studied topics were stress and pain, while studies on the welfare at slaughter and positive welfare indicators were scant. [ABSTRACT FROM AUTHOR]

Objectives: Our objectives were to examine what is known about the provision of healthcare services to older LGBT adults in the Nordic countries, identify knowledge gaps, map implications of this research for the education of healthcare professionals and delivery of healthcare, and identify key future research priorities to advance policy and practice for older LGBT adults in this region. Design: We conducted searches in nine databases. Peer-reviewed articles and PhD theses published in and after 2002 written in English, Norwegian, Swedish or Danish languages were included. 41 studies met our inclusion criteria. However, only eight of these studies focused specifically on older LGBT adults. Therefore, to answer all research questions, five book chapters about older groups were also included. Results: There were few studies from countries other than Sweden and few quantitative studies. Bisexual people represented a neglected group in research. The studies included showed that healthcare personnel lack knowledge on LGBT issues, particularly about older LGBT adults and non-binary gender identification. Older LGBT adults frequently reported being met with cis- and heteronormative expectations in healthcare encounters. For transgender people, access to medical treatment has been managed by gatekeepers influenced by a binary understanding of gender. Conclusions: Relevant measures to enhance practices are increased attention on LGBT issues in education; training of healthcare professionals; measures at the institutional level; and ensuring that transgender people identifying as non-binary receive the same quality of care as individuals identifying in a binary way. [ABSTRACT FROM AUTHOR]

This paper estimates the impacts of opening of borders and intensity of cross-border cooperation (CBC) on regional growth across European border regions. The difference-in-difference estimations show that the opening of national borders for free movement of people is associated with a 2.7% increase in regional gross value added (GVA) per capita for the border regions of Europe. Using an extension of this estimation based on European Commission-supported CBC projects data for the 2007–13 period (through the INTERREG programme), the results suggest that the doubling of the number of CBC project partners (per 100,000 population) is correlated with an increase of 2.3% in regional GVA per capita. These results confirm the positive economic benefits of European integration by means of CBC. For future research efforts, these findings also encourage the research community to investigate more deeply the channels through which CBC affects the socioeconomic development of border regions. [ABSTRACT FROM AUTHOR]

This paper contributes to the growing body of literature aimed at understanding the wide-ranging implications of the Belt and Road Initiative (BRI) by displaying the variety of contractual, formal and informal arrangements that China has entered with European states on a bilateral basis. Almost all European states have entered into one or another form of formal cooperation under the disguise of the BRI. In general, Eastern European states tend to have the highest degree of formal cooperation as official BRI members, whereas the picture is more diverse in the North-West of Europe. Cooperation ranges from investment-based infrastructure projects to joint financial investments, as well as projects in education or health. This complicated puzzle of arrangements ultimately favours China's influence and will change Europe's interconnectedness with China beyond transport connectivity. [ABSTRACT FROM AUTHOR]

In Europe, monitoring of breeding stock for Salmonella Pullorum (SP) or Salmonella Gallinarum (SG) infections is compulsory at the point of lay. Vaccinations against Salmonella Enteritidis (SE) and Salmonella Typhimurium (ST) are increasingly administered in Europe. These vaccines might induce cross-reactions in the rapid plate agglutination (RPA) SP/SG test due to shared O-antigens, possibly resulting in a lower test specificity. The extent to which the specificity of SP/SG serological tests is influenced by SE and/or ST vaccinations in the field has not been reported. In this paper, we report the diagnostic and flock specificity of the commercially available RPA SP/SG test using 1:2–1:16 serum dilutions on four panels of sera: SPF sera, field sera from flocks of varying age and SE/ST vaccination status, and reference sera from an international proficiency testing scheme. The results showed that the use of live SE/ST vaccines did not influence the specificity of the RPA SP/SG test. Inactivated vaccines showed a drop of the diagnostic specificity to 96.54% and a flock specificity of 34.1% when the 1:2 serum dilution was used. The 1:8 serum dilution showed a diagnostic specificity of 99.41% and a flock specificity of 86.4%. In conclusion, the use of SE/ST vaccines has either no effect or a modest effect on the specificity of the RPA SP/SG test used to monitor flocks. The main factors are the type of vaccine, and the serum dilution used for testing and a cut-off. [ABSTRACT FROM AUTHOR]

Evidence-based policies to monitor and manage migration flows require accurate data. Data collection on international migration flow statistics is based on a range of data sources and measures. Discrepancies in reported migration flow data are apparent when comparing flow statistics from receiving countries on the number of arriving migrants by their country of origin with statistics from sending countries on the number of departing migrants by their country of destination. In recent decades the relative incompleteness and non-comparability in reported migration statistics have motivated a number of initiatives to improve data in European countries. In this paper we illustrate graphically the discrepancies between sending and receiving migration flow statistics provided to Eurostat by European countries. We find a reduction of the discrepancies between receiving and sending migration flow data after the implementation of regulations to improve the availability and comparability of migration data. [ABSTRACT FROM AUTHOR]

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Europe has experienced a major boom of new breweries over the last thirty years, with thousands of new breweries being set up, even in regions where brewing has no history. So far, however, this microbrewing wave has not been systematically mapped. This paper presents a unique database of European breweries from 1990–2020. Using a series of maps and statistical analyses, it shows how breweries have gradually spread across Europe. Initially, microbreweries were being established in countries that are in a declining stage of the beer life-cycle from industrial breweries. After 2005 (and particularly in the 2010s), breweries reached other regions through neighbouring and hierarchical spatial diffusion. [ABSTRACT FROM AUTHOR]

The questions of how universities are governed and how they should be governed have recently gained attention throughout Europe. The history of universities shows a diffused pattern of repeated reform efforts. However, this situation has more or less exploded since the turn of the century, bringing in new modes of organising. In short we can observe a diffusion of more managerial forms of organising, leading to a situation where different governance ideals co-act. In this paper we analyse the interplay of several governance ideals as they play out in practice. We begin and end the essay by noting that collegiality is a modern, efficient and practical form of governance, but it never works entirely on its own; rather it interacts with other modes of governance. After an introduction of diverse modes of governance, analysed as ideal type models, we exemplify how those diverse modes mix in practices of governance and organising. A more theoretical argument that runs through the paper is a critique of the dominance of ideal types of discussions on university governance and in organisation theory more generally, to the extent that those ideal types tend to be reified. [ABSTRACT FROM AUTHOR]

The aim of this paper is to assess the contribution of European Territorial Cooperation (ETC) programmes operating in the Mediterranean area as a supporting way to achieve the renewable energy objectives established in European Union Directive 2009/28/EC. It addresses a combination of impact and thematic assessment applied to projects tackling solar energy over the period 2007-13. Observations indicate that although not always measurable, ETC contributions to the use and promotion of solar energy in the Mediterranean represent a key step forward in higher deployment. The paper also suggest alternatives to improve projects' outputs to be delivered in the new cycle 2014-20. [ABSTRACT FROM AUTHOR]

The number of immigrants moving to and settling in Europe has increased over the past decade, making migration one of the most topical and pressing issues in European politics. It is without a doubt that immigration has multiple impacts, in terms of economy, society and culture, on the European Union. It is fundamental to policy-makers to correctly evaluate people's attitudes towards immigration when designing integration policies. Of critical interest is to properly discriminate between subjects who are favourable towards immigration from those who are against it. Public opinions on migration are typically coded as binary responses in surveys. However, traditional methods, such as the standard logistic regression, may suffer from computational issues and are often not able to accurately model survey information. In this paper we propose an efficient Bayesian approach for modelling binary response data based on the generalized logistic regression. We show how the proposed approach provides an increased flexibility compared to traditional methods, due to its ability to capture heavy and light tails. The power of our methodology is tested through simulation studies and is illustrated using European Social Survey data on immigration collected in different European countries in 2016–2017. [ABSTRACT FROM AUTHOR]

The purpose of this paper is to investigate the links between a company's ultimate owner and the risk involved with financial performance. The study tests hypotheses on the relation between ultimate ownership origin and risk of return on assets. The research adopts cross-sectional data from a unique sample of 32,614 companies across 43 European countries with ultimate owners from 105 countries. The results indicate that the domestic ultimate owner is, in general, less likely to be a risk-taker than overseas investors. The research develops the nature of ownership-performance relations in the specific economic context of Europe. The results add robust evidence on attitudes towards performance risk of Europe wide ultimate owners. [ABSTRACT FROM AUTHOR]

Smart technologies with higher degrees of autonomy will be essential to achieve the next breakthrough in both agility and productivity in future manufacturing systems, often referred to as Industry 4.0. However, the technologies will also bring substantial design and integration challenges and novelty risks to manufacturing businesses. The aim of this paper is to analyse the current landscape and to identify the challenges for introducing smart technologies into manufacturing systems in Europe. Expert knowledge from both industrial and academic practitioners in the field was extracted using an online survey. A workshop was used to triangulate and extend the survey results. The findings indicate three main challenges for the ubiquitous implementation of smart technologies in manufacturing are: i) the perceived risk of novel technologies, ii) the complexity of integration, and iii) the consideration of human factors. Recommendations are made based on these findings to transform the landscape for smart manufacturing. [ABSTRACT FROM AUTHOR]

Background: Research capacity enhancement is needed in low- and middle-income countries (LMICs) for improved health, wellbeing, and health systems' development. In this article, we discuss two capacity-building projects, the African/Asian Regional Capacity Development (ARCADE) in Health Systems and Services Research (HSSR) and Research on Social Determinants of Health (RSDH), implemented from 2011 to 2015. The two projects focussed on providing courses in HSSR and social determinants of health research, and on developing collaborations between universities, along with capacity in LMIC universities to manage research grant submissions, financing, and reporting. Both face-to-face and sustainable online teaching and learning resources were used in training at higher postgraduate levels (Masters and Doctoral level). Design: We collated project meeting and discussion minutes along with project periodic reports and deliverables. We extracted key outcomes from these, reflected on these in discussions, and summarised them for this paper. Results: Nearly 55 courses and modules were developed that were delivered to over 920 postgraduate students in Africa, Asia, and Europe. Junior researchers were mentored in presenting, developing, and delivering courses, and in preparing research proposals. In total, 60 collaborative funding proposals were prepared. The consortia also developed institutional capacity in research dissemination and grants management through webinars and workshops. Discussion: ARCADE HSSR and ARCADE RSDH were comprehensive programmes, focussing on developing the research skills, knowledge, and capabilities of junior researchers. One of the main strengths of these programmes was the focus on network building amongst the partner institutions, where each partner brought skills, expertise, and diverse work cultures into the consortium. Through these efforts, the projects improved both the capacity of junior researchers and the research environment in Africa, Asia, and Europe. [ABSTRACT FROM AUTHOR]

This study investigates the skill structures of European countries and their transformations from the perspective of capability development. The constructed skill space illustrates the skill sets of European nations based on product space methodology by linking skill occupation and occupation–country data from 2011 to 2018. The results show that there are remarkable differences in skill structures among countries, and there is a strong path dependence in skill development. The findings suggest that skill convergence is unlikely to occur and that skill inequality among countries requires serious consideration. [ABSTRACT FROM AUTHOR]

The earth is continually bombarded by high-energy cosmic ray particles, and the worldwide average exposure to cosmic rays represents about 13% of the total annual effective dose received by the population. Therefore, assessment of cosmic ray exposure at the ground level is of great interest to better understand population exposure to ionizing radiation. This paper presents and describes the European Annual Cosmic-Ray Dose Map at 1 km resolution (Main Map). TheMain Mapdisplays the annual effective dose that a person may receive from cosmic rays at the ground level, which ranges from 301 to 3955 μSv. Moreover, thanks to the availability of population data, the annual cosmic-ray collective dose has been evaluated and population-weighted average annual effective dose (per capita) due to cosmic ray has been estimated for each European country considered in this study. The accuracy of the present study has been confirmed by comparing our results with those obtained using other models. [ABSTRACT FROM PUBLISHER]

Recent global and regional assessments of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) show that Nature's Contributions to People (NCP) are under an alarming threat due to the continuing loss of biodiversity. These assessments call for increasing conservation efforts and a more sustainable use of biodiversity to enhance the chances of halting biodiversity loss and reversing current trends. One of the strategies to achieve change is to mainstream biodiversity into sectoral policies. Mainstreaming, a concept that can be traced back to the Brundtland report, promotes the integration of the environment into political, societal, and economic planning and decision-making. Based on the review of key studies undertaken during the regional assessment for Europe and Central Asia, we develop a stepwise approach to analyze the current status of mainstreaming of biodiversity and NCP. The approach can be used both for policy design purposes and diagnostic evaluations. It demonstrates that mainstreaming has the potential to improve the conservation and sustainable use of biodiversity as well as the sustained provision of NCP. However, based on the status of implementation across Europe and Central Asia, we conclude that mainstreaming needs to be pursued and implemented in a stronger and more systematic way. The results of our assessment provide important input to national strategies and policies but also to the ongoing process of the Conference of the Parties to the Convention on Biological Diversity while developing the post-2020 global biodiversity framework. [ABSTRACT FROM AUTHOR]

A region's science output depends on several spatial factors. A generalized least squares function with random effects was estimated to gauge the impact of such factors in European NUTS2 regions. The main findings are that output is positively associated with the number of researchers in higher education institutions and negatively associated with the Herfindahl index of disciplinary specialization. Regions with old universities and good accessibility are also more productive, but these effects are mostly limited to Europe's core. Most leading science regions are in western or northern Europe. They combine large agglomerations of university scientists, disciplinary diversity, old university traditions, and good interregional accessibility. [ABSTRACT FROM AUTHOR]

The toxicity of atractyloside/carboxyatractyloside is generally well recognized and commonly ascribed to the inhibition of mitochondrial ADP/ATP carriers, which are pivotal for oxidative phosphorylation. However, these glycosides may 'paralyze' additional target proteins. This review presents many facts about atractyloside/carboxyatractyloside and their plant producers, such as Xanthium spp. (Asteraceae), named cockleburs. Published studies and other information were obtained from databases, such as 'CABI - Invasive Species Compendium', 'PubMed', and 'The World Checklist of Vascular Plants', from 1957 to December 2022. The following major keywords were used: 'carboxyatractyloside', 'cockleburs', 'hepatotoxicity', 'mitochondria', 'nephrotoxicity', and 'Xanthium'. In the third decade of the twenty first century, public awareness of the severe toxicity of cockleburs is still limited. Such toxicity is often only perceived by specialists in Europe and other continents. Interestingly, cocklebur is among the most widely distributed invasive plants worldwide, and the recognition of new European stands of Xanthium spp. is provided here. The findings arising from field and laboratory research conducted by the author revealed that (i) some livestock populations may instinctively avoid eating cocklebur while grazing, (ii) carboxyatractyloside inhibits ADP/GDP metabolism, and (iii) the direct/indirect target proteins of carboxyatractyloside are ambiguous. Many aspects of the Xanthium genus still require substantial investigation/revision in the future, such as the unification of the Latin nomenclature of currently distinguished species, bur morphology status, true fruit (achene) description and biogeography of cockleburs, and a detailed description of the physiological roles of atractyloside/carboxyatractyloside and the toxicity of these glycosides, mainly toward mammals. Therefore, a more careful interpretation of atractyloside/carboxyatractyloside data, including laboratory tests using Xanthium-derived extracts and purified toxins, is needed. [ABSTRACT FROM AUTHOR]

The coronavirus epidemic (COVID19) has affected the global economy and the services sector. Quarantine measures related to travel restrictions have led to an unprecedented decline in the tourism industry with repercussions on tourism service providers, transport companies and state budgets. Travel is necessary for tourism, therefore, any factor that prevents travel can have a profound impact on the tourism industry. In the current pandemic context, the forecast in the field of tourist travel has played an important role in supporting the revival of this sector. In this study, econometric and interpretive methods were combined to predict the demand. In this study we approached a prediction model that is based on the seasonal stationary and adjustment of observed and FFT data. Experimental results show that the proposed prediction model has demonstrated a good medium-term forecast and can be used successfully in short and medium periods of time. For a certification of the exploratory evaluation of tourism forecasts there were comparatively analyzed the results obtained for three countries in south-eastern Central Europe, countries with similar natural and anthropic tourist resources (Bulgaria, Croatia and Romania). [ABSTRACT FROM AUTHOR]

From ancient time the economies had periods of expansion followed by recession, each crisis was determined by various internal or external factors. With globalization, economic interconnection and the liberalization of resource exchange between states, high risk of economic crises have sprung up. The main purpose of the article is to determine a data model, using specific data analysis techniques, and based on it to study the economic cyclicality in Europe and the prediction of a possible economic crisis. The study was conducted on a number of 37 indicators selected from 11 categories, a set of 29 countries in Europe and over a period of 24 years (1995 − 2018) using the K-Means algorithm. Grouping the data for each country in three classes and describing each class by taking into account the variables with the highest discriminative power, leads to the main conclusion that in the next several years, an economic crisis in Europe has a high probability to be a reality. [ABSTRACT FROM AUTHOR]

Immune thrombocytopenia (ITP) is the most common acquired bleeding disorder. In both children and adults, the primary goal of any therapeutic approach consists of cessation of bleeding and its prevention. Several options are currently available for first-line therapy in Europe, including corticosteroids and intravenous immunoglobulin (IVIg) infusion, which has a similar efficacy and safety profile in both the pediatric and adult populations. When second-line therapy is needed in the pediatric setting, current guidelines recommend eltrombopag as the drug of choice. The aim of this article is to summarize the available evidence and present real-life experience on eltrombopag as second-line therapy in pediatric patients with ITP, with a focus on dosing and response to therapy as well as its tapering and discontinuation. In our setting, eltrombopag is associated with good safety profile as well as promising efficacy; dose de-escalation was feasible in 94% of cases and often reached very low pro/kg dosage, with full discontinuation in 15% of cases. In daily practice, a standardized approach for discontinuation of eltrombopag in pediatric patients with ITP is still lacking. Herein, an easy-to-use scheme for tapering and discontinuation in candidate pediatric patients is proposed that proposes 25% dose reduction every four weeks. In future management of pediatric ITP patients, it will be crucial to assess if thrombopoietin receptor agonists might be more effective in earlier phases of the disease and can modify the course of the disease. [ABSTRACT FROM AUTHOR]

The real-time automatic and accurate measurement of the mass of ultrafine particles is especially challenging due to their low concentrations and the interferences of larger particles. This work introduces a new method to estimate PM0.1 continuously. Based on the theoretical predictions of a 3-D chemical transport model, PM0.1 and N50 (number concentration of particles with a diameter above 50 nm) can have a very good correlation. This hypothesis is tested in this work by analyzing hourly measurements of size distributions, from different cities in Europe for a year. PM0.1 had a strong spatial and temporal correlation with N50 (R2 > 90%). The line passing through zero had an average slope of 0.16 ± 0.01 × 10−9 µg, for an assumed particle density equal to 1 g cm−3. This suggests that PM0.1 can be, at least in principle, measured indirectly but quite accurately and continuously by measuring N50 with a suitable condensation particle counter. Copyright © 2023 American Association for Aerosol Research [ABSTRACT FROM AUTHOR]

Background: Growing demand for Global Health (GH) training and the internationalisation of education requires innovative approaches to training. Blended learning (BL, a form of e-learning combining face-to-face or real-time interaction with computer-assisted learning) is a promising approach for increasing GH research capacity in low- to middle-income countries. Implementing BL, however, requires additional skills and efforts from lecturers. This paper explores lecturers' views and experiences of delivering BL courses within the context of two north-south collaborative research capacity building projects, ARCADE HSSR and ARCADE RSDH. Design: We used a qualitative approach to explore the experiences and perceptions of 11 lecturers involved in designing and delivering BL courses collaboratively across university campuses in four countries (South Africa, Uganda, India and Sweden). Data were collected using interviews in person or via Skype. Inductive qualitative content analysis was used. Results: Participants reported that they felt BL increased access to learning opportunities and made training more flexible and convenient for adult learners, which were major motivations to engage in BL. However, despite eagerness to implement and experiment with BL courses, they lacked capacity and support, and found the task time consuming. They needed to make compromises between course objectives and available technological tools, in the context of poor Internet infrastructure. Conclusions: BL courses have the potential to build bridges between low- and middle-income contexts and between lecturers and students to meet the demand for GH training. Lecturers were very motivated to try these approaches but encountered obstacles in implementing BL courses. Considerable investments are needed to implement BL and support lecturers in delivering courses. [ABSTRACT FROM AUTHOR]

The paper explores the ways in which university-based Teacher Education Departments in Greece have operated to promote changes to their undergraduate curricula. Our research approach views these changes as responses to the policies of the European Union and the Bologna Process for the 'modernisation' of higher education systems across Europe. Data are drawn from qualitative analyses of 18 curricula in two periods of their development, the middle of the 1990s and the late 2000s. The analysis of the study is based on Bernstein's theoretical concepts of classification, framing and meaning orientations, and describes basic types of university curricula regarding content organisation, pedagogical practices of teaching and learning, and knowledge evaluation. The findings reveal that, along with the disciplinary and professional criteria for knowledge recontextualisation, which have traditionally been legitimate in the field of Teacher Education, forms of weakly classified knowledge systematically oriented to problem-solving professional practices and school effectiveness are gradually crystallising and tending to become dominant. We argue that the marked shifts in the pedagogical means of teacher education may run the risk of thinning out teachers' knowledge base and de-professionalising their practices and identities. [ABSTRACT FROM AUTHOR]

Trust is an issue to which Keynesians and post-Keynesians have paid relatively little attention. However, properly understood it is an aspect of almost all activity, including key elements of socio-economic reality. Without trust, market exchange is at the very least problematic, if not impossible. Moreover, trust is intrinsic to a variety of issues with which Keynes, and subsequent Keynesianism have been concerned. In this paper we provide a general social theory conceptualisation of trust and then set out some of the areas where this concept resonates with the work of Keynes in terms of the role of conventions. Conventions quintessentially involve trust and that trust can be unstable, can be withdrawn and can require rebuilding. We illustrate this with reference to central bank policy and the Bank of England's introduction of Forward Guidance. Exploring the problem of trust in the context of banking also highlights a challenge for the continued relevance of Keynes' work. We now live in a neoliberal world and this provides a quite different context for state intervention than was previously the case. Keynes' work is now an argument for the alternative, and as such it requires more than a technical economic argument, it must also address the problem of trust in state policy-makers. We briefly illustrate the challenge this poses with reference to Europe. [ABSTRACT FROM AUTHOR]

Background: Women experience poorer health than men despite their longer life expectancy, due to a higher prevalence of non-fatal chronic illnesses. This paper aims to explore whether the unequal gender distribution of roles and resources can account for inequalities in general self-rated health (SRH) by gender, across social classes, in a Southern European population. Methods: Cross-sectional study of residents in Catalonia aged 25-64, using data from the 2006 population living conditions survey (n=5,817). Poisson regression models were used to calculate the fair/poor SRH prevalence ratio (PR) by gender and to estimate the contribution of variables assessing several dimensions of living conditions as the reduction in the PR after their inclusion in the model. Analyses were stratified by social class (non-manual and manual). Results: SRH was poorer for women among both non-manual (PR 1.39, 95% CI 1.09-1.76) and manual social classes (PR 1.36, 95% CI 1.20-1.56). Adjustment for individual income alone eliminated the association between sex and SRH, especially among manual classes (PR 1.01, 95% CI 0.85-1.19; among non-manual 1.19, 0.92-1.54). The association was also reduced when adjusting by employment conditions among manual classes, and household material and economic situation, time in household chores and residential environment among non-manual classes. Discussion: Gender inequalities in individual income appear to contribute largely to women's poorer health. Individual income may indicate the availability of economic resources, but also the history of access to the labour market and potentially the degree of independence and power within the household. Policies to facilitate women's labour market participation, to close the gender pay gap, or to raise non-contributory pensions may be helpful to improve women's health. [ABSTRACT FROM AUTHOR]

To investigate the spectrum of rat-borne pathogens circulating in Europe a systematic review spanning across 55 European countries during the years 1995–2016 was performed. The study surveyed viruses, bacteria, macroparasites and unicellular eukaryotes (protozoa). Fifty-three different infectious agents, all with zoonotic potential, were reported to be carried by commensal rats; 48 by the brown rat (Rattus norvegicus) and 20 by the black rat (R. rattus). There was a tendency for rural areas to harbour more rat-borne microbes than urban areas regarding the brown rat, but the opposite could be observed for the black rat. The study clearly indicated that an improved surveillance on wild rats is needed in Europe, and further indicated the pathogens and geographical areas where the major focus is required. For example, six zoonotic microbes seemed to be clearly more geographically widespread in Europe than others; virulent or resistant E. coli, pathogenic Leptospira spp., Hymenolepis diminuta, H. nana, Capillaria hepatica and Toxoplasma gondii. [ABSTRACT FROM AUTHOR]

Purpose: This discussion paper aims to explore the need of a clarified definition of master's level mental health nursing competencies in terms of knowledge, skills and attitudes in a European context. Mental health service users have, in spite of their right to equal overall health, higher rates of physical illness and are more likely to experience premature death than the general population. Implementation of a holistic concept of health comprising mental, physical and social aspects of health in mental health services has previously proved to be challenging. Methods: Master's level mental health nursing competencies in recent literature are discussed and illuminated in terms of knowledge, skills and attitudes in order to enable the promotion of equal overall health among service users in mental health services. Results: The discussion show contents, values and utility of master's level mental health nursing competencies in mental health services and contribute to reduced role ambiguity by distinguishing master's level responsibilities from undergraduate nursing tasks and obligations of other professionals in mental health care. Conclusion: This discussion paper shapes implications for developments in master's level mental health nursing education curricula. [ABSTRACT FROM AUTHOR]

This study seeks to investigate the impact of strengthened requirements for clinical evaluation for medical device manufacturers in Europe due to the new Medical Device Regulations. Qualitative interviews were conducted with eight clinical evaluation consultants from eight different European countries who review and approve clinical evaluation reports for manufacturers prior to their submission to notified bodies. The study describes the sources of device clinical evaluation evidence and describes the consultants' recommendations and challenges encountered when reviewing Clinical Evaluation Reports. The findings from the study demonstrate that understanding what constitutes sufficient clinical evidence poses the biggest challenge to the generation of an MDR-compliant Clinical Evaluation Report. Additionally, the study identified a knowledge and skills gap in the generation and assessment of acceptable regulatory and clinical data. Further, there is heterogeneity in the reviews of Clinical Evaluation Reports received by consultants and inadequate guidance to enable compliance by manufacturers. This study found that some manufacturers of certain CE-marked medical devices are planning to remove them from the EU market upon expiration of their certificate, and in the case of new innovative devices, some manufacturers may launch in other non-EU markets. [ABSTRACT FROM AUTHOR]

Palingenia Burmeister, 1839, is a small but intensively debated genus of mayflies due to the controversial taxonomy of the species belonging to it. Once widespread throughout Europe, Palingenia longicauda (Olivier, 1791), an iconic species of large pristine rivers, has lost most of its original range, but conservation efforts are greatly hampered by its morphology, which is similar to the sympatric P. fuliginosa (Georgi, 1802) and the peripatric P. sublongicauda Tshernova, 1949. Based on the revision of Soldán's original collection, supplemented with fresh material from southeastern Europe, we analyzed 213 adult male specimens from 15 different locations from the presently known distribution area of Palingenia in Europe. Principal Component Analysis (PCA) based on the morphometry results of penis morphology and eye distances showed no significant differences among the analyzed populations. Further, the mtCOI barcode sequence data of 73 individuals from the known range of Palingenia species in southeastern Europe represented highly similar populations genetically, with no differentiation. These results show the presence of only one species in southeastern Europe, P. longicauda, thus disproving the distribution of P. fuliginosa in this region. The taxonomic status of P. sublongicauda remains doubtful, as no type material or fresh material from the locus typicus of the species was available for this study. A comprehensive revision of Palingenia, including additional species from Asia and the Indomalayan regions, is highly recommended to reevaluate the species composition of Palingenia and detect the most closely related taxa of the single P. longicauda in Europe. [ABSTRACT FROM AUTHOR]

According to Neil Rollings and Laurent Warlouzet, the historical analysis of the European competition policy has been a priority in the research on institutions but the reaction of companies to these policies has received less attention. This study highlights the importance of analyzing how public policies affect business strategies in innovation. More specifically, how the policy adopted by the High Authority of the ECSC regarding the scrap market influenced the strategies implemented by the steelmakers in the innovation of their production processes. The High Authority banned exports and established maximum prices and a system to equalise internal prices with import prices. This policy was considered a success by both institutions and companies. It decisively influenced the scrap price to be maintained at affordable levels in Europe. But this success in resolving the scrap problem created a larger one as it delayed innovation. This was the scrap paradox suffered by Europe. [ABSTRACT FROM AUTHOR]

With the current expansion of vector-based research and an increasing number of facilities rearing arthropod vectors and infecting them with pathogens, common measures for containment of arthropods as well as manipulation of pathogens are becoming essential for the design and running of such research facilities to ensure safe work and reproducibility, without compromising experimental feasibility. These guidelines and comments were written by experts of the Infravec2 consortium, a Horizon 2020-funded consortium integrating the most sophisticated European infrastructures for research on arthropod vectors of human and animal diseases. They reflect current good practice across European laboratories with experience of safely handling different mosquito species and the pathogens they transmit. As such, they provide experience-based advice to assess and manage the risks to work safely with mosquitoes and the pathogens they transmit. This document can also form the basis for research with other arthropods, for example, midges, ticks or sandflies, with some modification to reflect specific requirements. [ABSTRACT FROM AUTHOR]

This paper examines the determinants of European bank risk-taking during major financial crisis. Using a sample of banks from 26 countries over the period 2005–2015, we examine the nature of the relationship between bank risk, bank characteristics, regulatory, institutional and macroeconomic variables. We use a dynamic panel data modeling structure to capture the potential discrepancies in risk-taking behavior. We subdivide our sample into two sub-samples (East Europe and West Europe countries). We show that macroeconomic and regulatory variables seem to have non-negligible impact on bank risk-taking attitudes. We document that the relationship between bank risk, internal and external factors differs across samples. [ABSTRACT FROM AUTHOR]

Territorial Impact Assessment (TIA) is proposed as a critical tool in order to investigate the way policies affect spatial development and hence territorial cohesion. The paper introduces a TIA methodological model in relation to transport sector. The design of the methodological model is based on a quantitative evaluation framework that comprises a set of selected indicators applied in a cross-border area of southeast Europe, influenced by the operation of the Greek motorway system of Egnatia and its vertical axes. The indicators are grouped into three main fields of TIA, i.e. transport intermodality, polycentric spatial organization and cross-border territorial cooperation. The TIA’s indicators are approximated by quantitative analysis. The procedure concludes to an overall composite indicator measuring the ‘level of territorial cohesion’ along with some core results and the expected added value. It also highlights some key technical aspects about the routines used and proceeds to suggestions for further refinement. [ABSTRACT FROM AUTHOR]

How does the inherent norm of integration, notably to share risks among its members in good faith, become a self-sustaining practice? I address this question generally and for a critical case of a divisive institution, i.e. the evolution of sovereign bailout funding in the Euro Area since 2010. Community building between states is a potential outcome of solidaristic practices, reinforced by positive feedback processes. Inspired by Deborah Stone's [Stone, D. A. (1999). Beyond moral hazard: Insurance as moral opportunity. Connecticut Insurance Law Journal, 6(1), 12–46] work on insurance, I demonstrate that there are social mechanisms at play that favour the secular expansion of risk sharing between states. [ABSTRACT FROM AUTHOR]

Betula pendula purple rain is a variety of Betula pendula that is native to Europe and has important ornamental and economic value. In this study, we sequenced the complete chloroplast genome of B. pendula purple rain. This genome had a typical quadripartite structure with 160,552 bases, including a large single copy (LSC) region of 89,433 bases, a small single copy (SCC) region of 19,007 bases and two inverted repeat (IR) regions of 26,056 bases. The GC content of the chloroplast genome was 36% and contained 124 genes, including 79 protein-coding genes, 8 rRNA genes and 37 tRNA genes. The maximum likelihood phylogenetic analysis of reported chloroplast genomes showed that B. pendula purple rain was most closely related to Betula occidentalis and Betula platyphylla. [ABSTRACT FROM AUTHOR]

This research focuses on the impact of regional entrepreneurial activity on employment growth. Specifically it analyses whether new firm formation in European NUTS-2 regions can stimulate job creation and drive employment growth. [ABSTRACT FROM PUBLISHER]

Objectives: To evaluate the experienced barriers of care for treatment-seeking trans individuals (TSTG) in three large European clinics. Methods: An online follow-up questionnaire was filled out by 307 TSTG individuals as part of the research protocol of the European Network for the Investigation of Gender Incongruence (ENIGI). Data was collected during follow-up in 2017/2018, around 5 years after participants had their initial clinical appointments in Ghent (Belgium), Amsterdam (the Netherlands), or Hamburg (Germany). Background characteristics, country, treatment characteristics and mental health were analyzed in relation to experienced barriers of care (EBOC, measured though agreement with statements). Results: The majority of participants reported various EBOC, oftentimes more than one. The most-frequently reported EBOCs pertained to the lack of family and friends' support (28.7%, n = 88) and travel time and costs (27.7%, n = 85), whereas around one-fifth felt hindered by treatment protocols. Also, a significant share expressed the feeling that they had to convince their provider they needed care and/or express their wish in such way to increase their likelihood of receiving care. A higher number of EBOCs reported was associated with more mental health problems, lower income and female gender. Conclusions: A substantial number of TSTG individuals within three European health care systems experiences EBOCs. EBOCs relate to both personal and systemic characteristics. These findings can help health care providers and centers to improve care. More research must be done to better understand the diversity among TSTG individuals and the corresponding barriers experienced. Supplemental data for this article is available online at https://doi.org/10.1080/26895269.2021.1964409 [ABSTRACT FROM AUTHOR]

The quality of life has been an attractive topic for several decades, and it has received attention in the scientific, political and public spheres. However, in a growing number of studies aimed at assessing the quality of life, inconsistencies persist in the definition, theoretical underpinnings and in approaches to assessing the quality of life. This study aims to compare the results of different methods of aggregating quality of life indicators into a synthetic index. The synthesis of individual sub-indices results in a final quality of life index and a typology which describes the variability arising from using different index calculation methods. The individual approaches to the calculations confirm the partial robustness of the results which, at the same time, can be an inspiration for a range of tasks where the parallel use of different methods reveals interesting internal relationships in the analysed data. [ABSTRACT FROM AUTHOR]