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Grassland plays an indispensable role in the stability and development of terrestrial ecosystems. Quantitatively assessing grassland resilience is of great significance for conducting research on grassland ecosystems. However, the quantitative measurement of resilience is difficult, and research on the spatio-temporal variation of grassland resilience remains incomplete. Utilizing the Global Land Surface Satellite (GLASS) leaf area index (LAI) product derived from MODIS remote sensing data, along with land cover and meteorological data, this paper constructed the grassland resilience index (GRI) in the west Songnen Plain, China, a typical region with salt and alkali soils. This paper analyzed the spatio-temporal changes of the GRI and explored the contribution of climate factors, human activities, and geographical factors to the GRI. The results revealed that from 2000 to 2021, the GRI in the study area ranged from 0.1 to 0.22, with a multi-year average of 0.14. The average GRI exhibited a pattern of high-value aggregations in the north and low-value distributions in the south. Trend analysis indicated that areas with an improved GRI accounted for 59.09% of the total grassland area, but there were still some areas with serious degradation. From 2000 to 2015, the latitude and mean annual temperature (MAT) were principal factors to control the distribution of the GRI. In 2020, the mean annual precipitation (MAP) and MAT played important roles in the distribution of the GRI. From 2000 to 2021, the influence of human activities was consistently less significant compared to geographical location and climate variables. [ABSTRACT FROM AUTHOR]

Understanding changes of soil organic carbon (SOC) in top layers of croplands and their driving factors is a vital prerequisite in decision-making for maintaining sustainable agriculture. However, high-precision estimation of SOC of croplands at regional scale is still an issue to be solved. Based on soil samples, synthetic image of bare soil and geographical data, this paper predicted SOC density of croplands using Random Forest model in the Black Soil Region of Jilin Province, China in 2005 and 2020, and analyzed its influencing factors. Results showed that random forest model that integrates bare soil composite images improve the accuracy and robustness of SOC density prediction. From 2005 to 2020, the total SOC storage in croplands decreased from 89.96 to 82.79 Tg C with an annual decrease of 0.48 Tg C yr−1. The mean value of SOC density of croplands decreased from 3.42 to 3.32 kg/m2, and high values are distributed in middle parts. Changes of SOC represented significant heterogeneity spatially. 62.14% of croplands with SOC density greater than 4.0 kg/m2 decreased significantly, and 38.60% of croplands with SOC density between 2.5 and 3.0 kg/m2 significantly increased. Climatic factors made great contributions to SOC density, however, their relative importance (RI) to SOC density decreased from 44.65% to 37.26% during the study period. Synthetic images of bare soil constituted 23.54% and 26.29% of RI in the SOC density prediction, respectively, and the contribution of each band was quite different. The RIs of topographic and vegetation factors were low but increased significantly from 2005 to 2020. This study can aid local land managers and governmental agencies in assessing carbon sequestration potential and carbon credits, thus contributing to the protection and sustainable use of black soils. [ABSTRACT FROM AUTHOR]

The paper presents the development of a GaN DC–DC power converter with a pre-driver module and power device based on a monolithic integrated GaN E/D-mode metal–insulator–semiconductor high electron mobility transistors (MIS-HEMTs) platform. The pre-driver module with direct coupled field effect transistor logic circuit structure has been monolithically integrated with a GaN power transistor on a Si-based AlGaN/GaN commercial epitaxial wafer. The MIS-HEMTs structure adopts an insulated gate dielectric layer to suppress the leakage current and increase gate voltage robustness. The GaN-based floating buck converter employs a 1 mH inductor and a 9 μ F capacitor to achieve 35 V–5 V power conversion. As a result, the pre-driver module is capable of delivering a 10 V driving voltage. GaN monolithic integration of the pre-driver module and power device can reduce the system area in the DC–DC application, which allows for an integrated chip size of 1.8 mm2. [ABSTRACT FROM AUTHOR]

This paper presents a monolithic GaN driver with a deadtime generator (DTG) for half‐bridge DC‐DC buck converters. The proposed GaN integrated circuits (ICs) were fabricated in a 3 µm enhancement‐mode GaN MIS‐HEMTs process. The integrated DTG converter can operate at 250°C with a large gate swing of 10 V, and it exhibits a maximum efficiency of 80% at high temperatures, with VIN= 30 V at 100 kHz. The monolithic GaN DTG driver requires one control signal and generates a deadtime of fewer than 0.13 µs at high temperatures up to 250°C. The proposed DTG converter is compared to an integrated GaN converter without DTG (w/o) under various conditions. At high temperatures, the optimized GaN DTG converter shows better performance than the GaN converter w/o at high load currents, in terms of smaller voltage overshoots and better efficiency as well. This work demonstrates a simple GaN deadtime method for high temperature (HT) GaN power converters. [ABSTRACT FROM AUTHOR]

This article proposes a fixed switching frequency (FSF)-based improved model predictive control (MPC) for a five-level active neutral-point clamped (5L-ANPC) converter. Compared to the conventional MPC for 5L-ANPC converter, the proposed MPC significantly reduces the computational burden while ensuring the balance of dc-link and flying capacitor voltages. The proposed MPC optimally selects the control voltage vectors to reduce common mode voltage (CMV), leading to a small CMV of the converter. Using three voltage vectors action per control cycle in MPC, FSF is achieved. Steady-state and dynamic performances of the proposed MPC have been evaluated by experiments. The results verify the feasibility and effectiveness of the proposed MPC method. [ABSTRACT FROM AUTHOR]

As one of the promising power interfaces between the energy storage components and the dc link, dual active bridge (DAB) converters have gained extensive researches. Its reliability and healthy operation under one or even multiple unexpected open-circuit faulty conditions have become one of the main design challenges. Conventional fault detection (FD) and fault isolation (FI) methods exhibit obvious limitations in terms of detection speed, number of FD signatures, universality, accuracy, computational burden, and implementation cost due to the added sensors. To fill in this gap, this article presents a robust, fast, accurate, and low-cost FD and FI method for DAB converters, which is applicable under various operational conditions. The proposed method will adopt the differential switch node voltage between the primary and secondary bridge of DAB converters as the universal fault signature for complete FD and FI. The corresponding fault diagnostic circuit is simple, compact, low cost, and easy in implementation. This sensorless fault diagnostic technique can detect the switch open-circuit fault within a quarter of a switching cycle and realize the fault isolation accurately. A DAB prototype with a fault diagnostic circuit was designed, and main experimental results under various faulty conditions were provided to validate the advantages of the proposed method. [ABSTRACT FROM AUTHOR]

The partial power processing (PPP) concept has been extensively employed in many two-port converters to achieve high efficiency and high-power density by modifying one of the original converter ports to be connected in series between input and output. This is attractive but is confined to two-port applications, and how to extend it to multiport applications is not clear. Hence, this article aims to explore a generalized PPP multiport scheme by arranging the connection of the module rather than the converter. For a PPP single-input(output)-N-outputs(inputs) converter, one terminal of all N+1 modules is connected together to construct a radial structure, and another terminal is series/parallel connected with the input/output port. Each module only needs to process partial power caused by the voltage or current difference between input and output. Therefore, the required power rating of components is effectively reduced, contributing to low cost as well as low power loss. In this article, a PPP single-input dual-output converter with active bridge modules is also taken as an example to be introduced in detail, designed and experimented upon, which validates that high efficiency and high-power density can be achieved. [ABSTRACT FROM AUTHOR]

Class D power amplifiers, one of the most critical devices for application in sound systems, face severe challenges due to the increasing requirement of smartphones, digital television, digital sound, and other terminals. The audio power amplifier has developed from a transistor amplifier to a field-effect tube amplifier, and digital amplifiers have made significant progress in circuit technology, components, and ideological understanding. The stumbling blocks for a successful power amplifier are low power efficiency and a high distortion rate. Therefore, Class D audio amplifiers are becoming necessary for smartphones and terminals due to their power efficiency. However, the switching nature and intrinsic worst linearity of Class D amplifiers compared to linear amplifiers make it hard to dominate the market for high-quality speakers. The breakthrough arrived with the GaN device, which is appropriate for fast-switching and high-power-density power electronics switching elements compared with traditional Si devices, thus, reducing power electronic systems' weight, power consumption, and cost. GaN devices allow Class D audio amplifiers to have high fidelity and efficiency. This paper analyzes and discusses the topological structure and characteristics and makes a judgment that Class D amplifiers based on GaN amplifiers are the future development direction of audio amplifiers. [ABSTRACT FROM AUTHOR]

Conventional global maximum power point tracking (GMPPT) algorithms show limited tracking speed and accuracy due to the unnecessary peak search considering the complexity of partial shading conditions (PSCs). This paper proposes a novel power incremental (PI) algorithm for photovoltaic GMPPT and partial shading detection with the aid of the reference voltage line (RVL), representing the voltage of possible peaks based on the derived analytical expressions. The proposed analytical solution can detect the occurrence of PSCs easily and never overlook GMPP. Furthermore, both the tracking speed and the efficiency can be improved due to the quick allocation of GMPP and the reduced search area. The proposed RVL-PI-GMPPT algorithm is straightforward without sophisticated searching iterations, which can reduce the computational burden. Combined with the low-cost feature without additional temperature or irradiance sensors, the proposed algorithm is very suitable for the practical engineering design. Both the simulations and experiments under various PSC patterns validated the effectiveness of the proposed algorithm. Conducted fair comparisons with other popular GMPPT methods, the average percentage change of tracking time by implementing the proposed RVL-PI-GMPPT algorithm under three-peaks PSC patterns is $\bf 108.9\%$ compared with the PSO method and $\bf 209.9\%$ compared with the 0.8 $V_{oc}$ model method, respectively. [ABSTRACT FROM AUTHOR]

Pulse test techniques are widely adopted in characterizing both the static and dynamic performances of semiconductor devices considering various device structures and operating conditions. For gallium nitride (GaN) devices, due to the current collapse phenomenon, fast and accurate measurement of their key electrical parameters, such as dynamic ON-state resistance ${R}_{\text {ds}, \mathrm{\scriptscriptstyle ON}}$ , switching rising time, fall time, switching losses, and short-circuit (SC) robustness, becomes essential. This article presents a comprehensive review of state-of-the-art pulse test setup methods such as the double-pulse test (DPT), multiple-pulse test (MPT), and SC test (SCT) for the first time, which facilitates the GaN device structure design and practical applications in high efficiency and power density power converters. [ABSTRACT FROM AUTHOR]

In this article, an efficient model predictive control (MPC) using virtual voltage vectors for three-phase three-level converters is proposed. The proposed MPC achieves constant switching frequency by applying four voltage vectors, including one virtual voltage vectors and three other voltage vectors, in each control cycle. In addition, to reduce the computational burden, two-stage MPC approach is adopted. The first stage chooses one of six medium voltage vectors that minimizes the cost function. Then, in the second stage, these voltage vectors including virtual voltage vectors, which locate the same sector with the optimal medium voltage vector, are involved in the MPC optimization. The advantages of the proposed MPC over the classical MPC have been validated through experimental results. [ABSTRACT FROM AUTHOR]

Dual-active-bridge (DAB) converters have been widely recognized as one promising topology for high-frequency-link power conversion applications. However, one critical issue concerning DAB converters is the transient dc-bias current due to the voltage-second imbalance, which may occur frequently in typical dynamic operations of DAB converters such as the start-up, sudden load or output voltage change, and power flow direction change. Due to the high-frequency operation, the dc-bias current of DAB converters will impose more harm to magnetic components because of the limited range of operating flux density and possible magnetic saturation compared with the counterpart low-frequency dc-bias current. Over the past several years, extensive researches have been conducted to address the high-frequency transient dc-bias current of DAB converters under different phase-shift modulation strategies such as single phase shift, extended phase shift, and triple phase shift. In this article, a comparative review of typical dc-bias current mitigation strategies under typical phase-shift strategies for DAB converters is presented. An experimental evaluation of selected strategies under various scenarios is conducted in terms of the settling time, inductor current stress, efficiency, switching number, and implementation complexity. This article ends up with an overview of high-frequency dc-bias mitigation strategies and a discussion for the further optimization. [ABSTRACT FROM AUTHOR]

This letter demonstrates a monolithic voltage reference based on technology of aluminum-gallium- nitride/gallium-nitride (AlGaN/GaN) Metal-Insulator- Semiconductor (MIS) High-Electron-Mobility Transistors (HEMTs). The simple but robust voltage reference consists of only two transistors (2T), namely a depletion-mode (D-mode) device and an enhancement-mode (E-mode) device. This implementation features a 2T structure to generate a predictable reference voltage while maintaining high stability over wide ranges of the supply voltage and temperature. Experimental results show a realization of 2.53 V reference voltage ($\text{V}_{REF}$) for a supply voltage range of 4.8 to 50 V, a maximum $\text{V}_{REF}$ line sensitivity of 0.077 % $/\text{V}$ and a temperature coefficient of 26.2~33.9 ppm/°C in the temperature range from −25 to 250 °C. The voltage reference circuit also features a fast initialization with a start-up time of 387 ns at 25 °C and 841 ns at 250 °C. The results demonstrate a useful design and implementation of a thermally stable reference voltage for applications in biasing and sensing circuits to achieve the compact all-GaN monolithic integration of control/protection blocks in the smart power systems. [ABSTRACT FROM AUTHOR]

The dc power transmission system has been obviously attracting more research interests in recent years. In order to satisfy the high-reliability requirement of the dc power transmission system, the power converter should be able to keep uninterrupted operation after multiple unexpected faults. However, high fault-tolerant capability usually leads to the bulky redundant circuit, which increases the cost, volume, and complexity of the power converter. Thus, a fault-tolerant dual active bridge (DAB) converter is proposed to maintain the power transferring ability under multiple unexpected open-circuit faults (OCFs) conditions, which can significantly enhance the reliability of the dc power transmission system. By reconfiguring the central-tapped transformer and two symmetrical auxiliary inductors, the half-bridge conduction branch is built to maintain uninterrupted operation when a single or dual OCF has occurred. The proposed fault-tolerant strategy only requires four extra voltage sensors to detect and locate OCFs for the reconfiguration process. Thus, it significantly improves the system reliability with a low additional cost. Besides, the inductor current, transmission power, and the small-signal models of the proposed fault-tolerant converter have been presented. It proves the proposed fault-tolerant topology can smoothly switch between normal and postfault operation due to the constituency of the inductor current. Finally, the 250-W prototype is designed to verify the advantage of the proposed fault-tolerant DAB converter. [ABSTRACT FROM AUTHOR]

In this article, a low complexity finite-control-set model predictive control (FCS-MPC) based on the discrete space vector modulation (DSVM) is proposed for T-type three-phase three-level (3P-3L) converters. Different from the conventional FCS-MPC, 48 virtual voltage vectors (VVs) of the converter are constructed by real VVs based on the DSVM. Thus, the performance of 3P-3L converters is significantly improved and the peak amplitude of high-order harmonics concentrates at the sampling frequency. Furthermore, two-stage FCS-MPC based on virtual VVs is proposed to reduce the computation burden. Its first stage selects one of six virtual VVs that minimizes the current tracking error. Then, these candidate VVs located in the same sector as the optimal virtual VV selected in the first stage are evaluated in the second-stage optimization. Thus, the computational efficiency has been greatly improved. To verify the validity of the proposed control method and show its superiority over the conventional FCS-MPC, experimental results are presented. [ABSTRACT FROM AUTHOR]

With the increase of the component number, the power stress distribution among differential power processing (DPP) converters, control implementation, system cost, and reliability become the most challenging issues for a practical photovoltaic (PV) DPP system. This article introduces an improved power-rating balance (IPRB) control for the PV-to-bus based DPP architecture that ensures each PV submodule operate at its true maximum power point (MPP) while achieving more balanced power stress distribution and higher reliability. Specifically, a submodule-level finite-state-machine-based MPP tracking is implemented to guarantee always maximum power yield, whereas a string-level power-rating balancing (PRB) control is adopted to balance the unit-maximum proceeded power by DPP converters based on the built power flow model with respect to the string current. A comprehensive comparison of advanced control strategies for PV-to-bus DPP architectures, including least power point tracking, voltage equalization (VE) based PRB control, and the proposed IPRB, has been carried out with the mission-profile-based reliability assessment under different partial shading scenarios. Component-failure-rate-based reliability analysis shows that the PV-to-bus DPP architecture with the proposed IPRB control can significantly improve the system reliability. Main simulation and experimental evaluations are carried out to verify the effectiveness of the proposed control. [ABSTRACT FROM AUTHOR]

Monolithic GaN High Electron Mobility Transistor (HEMT)-integrated circuits are a promising application of wide band-gap materials. To date, most GaN-based devices behave as NMOS-like transistors. As only NMOS GaN HEMT is currently commercially available, its control circuit requires special design if monolithic integration is desired. This article analyzes the schematics of a GaN-based comparator, and three comparator structures are compared through ADS simulation. The optimal structure with the bootstrapped technique is fabricated based on AlGaN/GaN Metal–Insulator–Semiconductor (MIS) HEMT with the recessed gate method. The comparator has excellent static characteristics when the reference voltage increases from 3 V to 8 V. Dynamic waveforms from 10 kHz to 1 MHz are also obtained. High-temperature tests from 25 ° C to 250 ° C are applied upon both DC and AC characteristics. The mechanisms of instability issues are explained under dynamic working condition. The results prove that the comparator can be used in the state-of-art mixed-signal circuits, demonstrating the potential for the monolithic all-GaN integrated circuits. [ABSTRACT FROM AUTHOR]

Maximum power point tracking (MPPT) is required in PV power systems for the highest solar energy harvest. This article proposes a self-tuning scheme to improve the MPPT performance in terms of high accuracy and speed. The scheme adopts the reinforcement learning (RL) and Beta parameter for the highest MPPT performance. The tracking speed and accuracy are significantly improved since the RL algorithm is enhanced for high convergence speed, meanwhile, the guiding variable $\beta$ is introduced to constrain the exploration space. Simulation and experimental test are applied to validate the superior performance of the proposed solution following the EN50530 dynamic test procedure. [ABSTRACT FROM AUTHOR]

Power system inertia helps the grid to maintain frequency stability. However, as photovoltaic (PV) generation continuously displaces synchronous generators (SGs) and reduces system inertia, it may result in system failure. Virtual inertia control (VIC) technology has drawn increasing attention because it enables PVs to increase system inertia by mimicking the characteristics of SGs. Energy sources are needed to implement the VIC strategy. Energy storage systems (ESS) can be used to provide such energy. However, the high-cost is still hindering its large-scale adoption. Although constant reserve power in PV has recently been proposed as an alternative for ESS, it can cause unnecessary power losses during the PV system working at a stable state. This paper proposes a forecasting-based VIC (FB-VIC) and coordinated reserve strategy. FB-VIC enables the PVs to serve as an alternative inertia supplier without using ESS. PV generation is pre-reserved based on the solar forecasting results, either at PV plant about to be shaded for local curtailment or other unshaded PV plants providing virtual inertia. The coordinated reserve strategy decides how much to reserve at the selected PV plant. It makes the system more robust to forecasting errors. The simulation results reveal that the proposed method can improve system inertia and suppress the frequency variation in a shorter time. [ABSTRACT FROM AUTHOR]

The derivation and implementation of multiple-phase-shift-based switching surfaces for a dual active bridge (DAB) converter is the main focus of this article. First, the mathematical models of multiple natural switching surfaces under different operation states of DAB converters are derived, which lays the foundation to achieve a fast transient response during startup, sudden voltage reference, and load changing conditions. Moreover, in order to improve the overall performance of DAB converters systematically, a minimum-current-stress boundary control (MBC) is proposed that can reduce the inductor peak current stress and achieve fast dynamic response simultaneously by using the multiple-phase-shift-based switching surfaces. The analytical derivation of the proposed MBC is presented together with the simulation and experimental evaluations, which shows the superior performance of the proposed MBC algorithm in terms of the efficiency and dynamic response improvement under various operating conditions. [ABSTRACT FROM AUTHOR]

Novel normally-OFF AlGaN/GaN MIS-high electron mobility transistors (HEMTs) with a ZrOx charge trapping layer are proposed. The deposition of the ZrOx charge trapping layer on the partially recessed AlGaN in conjunction with the Al2O3 gate dielectric has been accomplished. The developed MIS-HEMTs exhibit a threshold voltage of 1.55 ± 0.4 V and a maximum drain current of 730 ± 6 mA/mm, while associated low ON-resistance of $7.1~\pm ~0.2~\Omega \cdot $ mm, for a gate to drain separation of 3 $\mu \text{m}$. The TCAD simulation results are presented to explore the charge trapping and de-trapping behaviors. Moreover, the devices exhibit a high breakdown voltage. The results indicate the merits of employing ZrOx charge trapping layer to realize the normally-OFF GaN devices with low ON-state resistance. [ABSTRACT FROM AUTHOR]

Compared with the conventional multilevel converters, the hybrid-clamped converter (HCC) reduces the number of power devices, which brings down the converter cost while enhancing its reliability for medium-voltage high-power applications. As one of typical medium-voltage HCCs, the single-phase, six-level HCC (6L-HCC) faces the main technical challenge of the voltage balance among five inner capacitors. Most of the existing pulsewidth modulation techniques cannot solve this problem. Advanced control methods that directly apply a selected voltage vector, such as the classical model predictive control (MPC), may fail to balance the inner capacitor voltages during low output frequencies. In view of this situation, this article proposes an improved MPC approach with autotuning weighting factors. It contributes to ensure excellent performance of 6L-HCC under all operating conditions with well-balanced inner capacitor voltages. Simulation and experimental results are proposed to verify the effectiveness of the proposed approach. [ABSTRACT FROM AUTHOR]

Thus, the corrected paragraphs are as follows: "A widespread closed-loop analog Class D amplifier covers integrators, modulators, output stage, low-pass filters, and loudspeakers (Figure 2). - Modulation i " which contain the below paragraphs, required consistent changes for a proper citation: "A widespread closed-loop analog Class D amplifier covers integrators, modulators, output stage, low-pass filters, and loudspeakers (Figure 2). And [29,30] presented a low-power class-D audio amplifier using a first-order sigma-delta modulator as a PDM modulator; this design can effectively improve efficiency". [Extracted from the article]

This article demonstrates the integrated comparators, hysteresis comparators, and sawtooth generators based on aluminum–gallium–nitride/gallium–nitride (AlGaN/GaN) metal–insulator–semiconductor high-electron-mobility transistors (MIS-HEMTs). The integrated circuits (ICs) exhibit thermal stability from 25 °C to 250 °C in both static and transient performances. The threshold voltage (Vth) in depletion (D)-mode MIS-HEMT is modulated from −8.9 to −2.4 V to optimize the performance of integrated comparator circuits. The comparator can realize a large and stable comparison range of 3–9 V and a high voltage swing of 9.1 V, while the hysteresis comparator exhibits a good noise-immunity ability and stable hysteresis output. The sawtooth generator with the hysteresis comparator features a high amplitude (6.1 V) sawtooth signal at 500 kHz to realize a compact structure applicable to the high-voltage mixed-signal circuits. These results show the feasibility of MIS-HEMT monolithic comparator circuits in conversion systems. [ABSTRACT FROM AUTHOR]

Previous literature has indicated that cyclin‐dependent kinase inhibitor 2 A (CDKN2A) is upregulated, while the Protein Inhibitor of Activated STAT1 (PIAS1) is downregulated in the liver tissues of obese mice. The current study aimed to investigate the relationship between CDKN2A and PIAS1 in the lipogenesis of fatty liver disease. In the C57BL/6J db/db mouse model and hepatocyte model of fatty liver, the expression pattern of CDKN2A, PIAS1, Protein arginine methyltransferase 1 (PRMT1) and CASP8 and FADD‐like apoptosis regulator (CFLAR) was characterized by RNA quantitative and Western blot analysis. The lipogenesis‐related genes (Srebp1c and Fas) in the liver tissues and cells were employed in the assessment of lipogenesis in response to gain‐ or loss‐of‐function of CDKN2A, PIAS1, PRMT1, and CFLAR, while triglyceride and fat content were evaluated in relation to fat accumulation. Western blot analysis was conducted to determine c‐Jun amino‐terminal kinase (JNK) phosphorylation, while the ubiquitination of CFLAR and SUMOylation of PIAS1 was examined by immunoprecipitation. PIAS1 and CFLAR were downregulated, while CDKN2A, PRMT1, and phosphorylation of JNK was elevated in the tissues and cells of the fatty liver models. Our results suggested that CDKN2A enhanced the SUMOylation of PIAS1 to reduce the expression of PIAS1. PRMT1 downregulated CFLAR by triggering its ubiquitination, while CFLAR repressed phosphorylation of JNK. The in vitro and in vivo results indicated that CDKN2A silencing prevented lipogenesis and fat accumulation by impairing the PRMT1‐dependent ubiquitination of CFLAR and blocking the phosphorylation of JNK. Taken together, the central observations of our study demonstrate that targeting CDKN2A contributes to the suppression of lipogenesis and fat accumulation in fatty liver disease. The findings of our study highlight the potential of CDKN2A as a promising target against fatty liver. [ABSTRACT FROM AUTHOR]

Dynamic performance of maximum power point tracking (MPPT) algorithms is important to ensure high-power output under practical operating conditions. In this article, after reviewing three dynamic test procedures, including stepped operation procedure, day-by-day operation procedure, and EN50530 dynamic test procedure, three typical MPPT algorithms such as the fixed-step-size perturb and observe (P&O), variable-step-size incremental conductance, and hybrid-step-size beta method are evaluated experimentally under the EN50530 dynamic test procedure. Two dynamic EN50530 test sequences are adopted for the performance evaluation to cover different irradiance changing conditions. The PV model for EN50530 dynamic test sequences is built, and the effects of wrong-step changes by using three MPPT algorithms are analyzed systematically. The experimental comparison of three MPPT algorithms in terms of the tracking routines, accumulated energy, and tracking efficiency is presented. The research shows that the 0.5% fixed-step-size P&O may fail to track the MPP due to the tracking drift, whereas the beta algorithm exhibits the highest tracking efficiency under both dynamic sequences. The average tracking efficiency improvement of the beta algorithm compared with other two algorithms are experimentally measured as $\text{24.2}\%$ and $\text{18.8}\%$ , respectively. [ABSTRACT FROM AUTHOR]

When the permanent magnet synchronous machine (PMSM) based electric vehicles (EV) are in the postcrash situations, the dc-bus capacitor voltage requires to be reduced quickly for the sake of electric shock risk prevention. Currently, due to the advantages of low cost, compact structure, and high reliability, the pure-winding-based discharge strategies are attracting increasing attentions. However, there are no theoretical criteria for judging whether a pure-winding-based method is suitable for bleeding a particular PMSM-based EV drive, not to mention the rules for opting for an effective discharge strategy among the instant nonzero d-axis, zero q-axis (NDZQ), long-cycle NDZQ, and the nonzero d-axis, nonzero q-axis (NDNQ) current control techniques. This article discusses the applicable occasions of the instant NDZQ, long-cycle NDZQ, and NDNQ discharge methods based on parametric analysis. On this ground the principles for determining whether an EV drive can adopt a pure-winding-based method for discharge are given. Meanwhile, the implementation procedures of the proposed criteria are detailed clearly. Finally, the proposed selection criteria are used for evaluating five different EV drives so as to select the corresponding winding-based discharge strategy for each system, and the effectiveness is verified by simulation or experiments. [ABSTRACT FROM AUTHOR]

When electric vehicles (EVs) encounter an emergency, the voltage of the dc-bus capacitor in the surface-mounted permanent magnet synchronous motor (SPMSM)-based powertrain requires to be reduced as fast as possible. In order to eliminate the disadvantages and synthesize the advantages of the traditional machine-winding-based and external bleeder-based discharge techniques, this article proposes a hybrid discharge strategy that can achieve 5-s discharge in the minimum sacrifice of the bleeder size and weight for any EV drives. For the purpose of evaluating the size reduction of the new method, the individual bleeder-based scheme is modeled and analyzed at first. Then, the combined discharge method is developed, which contains two sequential procedures: bleeding resistor (BR) design and discharge control algorithm design. The BR design process has to be implemented under extreme condition. But concerning that the emergency might occur at the moment when the machine operates below the maximum speed, three different discharge modes including full-power, partial-power, and bleeder-based discharge modes are developed. The proposed discharge techniques are verified by experiments that are conducted on a three-phase SPMSM drive system used for EVs. [ABSTRACT FROM AUTHOR]

Solar forecasting is one of the most promising approaches to address the intermittent photovoltaic (PV) power generation by providing predictions before upcoming ramp events. In this article, a novel multistep forecasting (MSF) scheme is proposed for PV power ramp-rate control (PRRC). This method utilizes an ensemble of deep ConvNets without additional time series models (e.g., recurrent neural network (RNN) or long short-term memory) and exogenous variables, thus more suitable for industrial applications. The MSF strategy can make multiple predictions in comparison with a single forecasting point produced by a conventional method while maintaining the same high temporal resolution. Besides, stacked sky images that integrate temporal–spatial information of cloud motions are used to further improve the forecasting performance. The results demonstrate a favorable forecasting accuracy in comparison to the existing forecasting models with the highest skill score of 17.7%. In the PRRC application, the MSF-based PRRC can detect more ramp-rates violations with a higher control rate of 98.9% compared with the conventional forecasting-based control. Thus, the PV generation can be effectively smoothed with less energy curtailment on both clear and cloudy days using the proposed approach. [ABSTRACT FROM AUTHOR]

Long non-coding RNAs (lncRNAs) have recently emerged as inflammation-associated biological molecules with a specific role in the progression of liver fibrosis conditions including non-alcoholic steatohepatitis (NASH). The aim of this study was to elucidate the effects of lncRNA nuclear enriched abundant transcript 1 (NEAT1), microRNA-129-5p (miR-129-5p), and paternally expressed gene 3 (PEG3) on the biological activities of hepatic stellate cells (HSCs) subjected to NASH. First, microarray-based analysis revealed upregulated PEG3 in NASH. Liver tissues from mice fed a methionine–choline-deficient (MCD) diet exhibited increased expression of NEAT1 and PEG3 along with lower miR-129-5p expression. A series of in vitro and in vivo assays were then performed on HSCs after transfection with shPEG3, miR-129-5p mimic, or treatment with pyrrolidine dithiocarbamate (PDTC), an inhibitor of the nuclear factor-kappa B (NF-κB) signaling pathway. Results confirmed the alleviated fibrosis by restoring miR-129-5p, while depleting PEG3 or NEAT1, as evidenced by the inactivation of HSCs. To sum up, NEAT1 can bind specifically to miR-129-5p and consequently regulate miR-129-5p and PEG3 expression in relation to the HSC activation occurring in NASH. Thus, NEAT1-targeted inhibition against miR-129-5p presents a promising therapeutic strategy for the treatment of NASH. [ABSTRACT FROM AUTHOR]