118 results on '"Baysal, Erkan"'
Search Results
2. Improved health-related quality of life after cardioneuroablation in patients with vasovagal syncope
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Baysal, Erkan, Mutluer, Ferit Onur, Dagsali, Alara Ece, Kumrulu, Umur Cengiz, Huang, Henry D., and Aksu, Tolga
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- 2022
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3. Decreasing time between first diagnosis of paroxysmal atrial fibrillation and cryoballoon ablation positively affects long-term consequences
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Baysal, Erkan, Okşul, Metin, Burak, Cengiz, Yalin, Kivanc, Soysal, Ali Ugur, Yalman, Hakan, Bozyel, Serdar, Guler, Tumer Erdem, Tanboga, Halil Ibrahim, and Aksu, Tolga
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- 2022
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4. The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19
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Işık, Ferhat, Çap, Murat, Akyüz, Abdurrahman, Bilge, Önder, Aslan, Burhan, İnci, Ümit, Kaya, İlyas, Taştan, Ercan, Okşul, Metin, Çap, Neşe Kanbal, Karagöz, Ali, and Baysal, Erkan
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- 2022
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5. Prognostic Value of Admission Lactate Level in Patients With Myocardial Infarction With ST Segment Elevation.
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Güven, Göksel, Şener, Yusuf Ziya, Cömert, Adnan Duha, Söner, Serdar, Öztürk, Cansu, Taştan, Ercan, Okşul, Metin, and Baysal, Erkan
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MYOCARDIAL infarction ,ST elevation myocardial infarction ,CONTRAST induced nephropathy ,PROGNOSIS ,LACTATES ,ACUTE coronary syndrome - Abstract
Lactate is a product of anaerobic metabolism and increases in states of tissue hypoxia. Furthermore, it is demonstrated that lactate level is correlated with the extent of infarct area and short term (30-day) mortality rates in patients with acute coronary syndrome with ST segment elevation (STE-ACS). Therefore, we aimed to test the prognostic value of this easily obtainable parameter on outcomes in patients presenting with STE-ACS. All adult patients who admitted with STE-ACS between 2019 and 2020 were screened. The cases with admission lactate levels were included. Patients were separated into two groups as low (<2mmol/l) and high (>2mmol/l) lactate groups. A total of 70 patients were enrolled. The mean age of the study population was 62.3 ± 15.0 years and 53 (75.7%) of them were male. The most common infarct related artery was the left anterior descending (LAD) artery. The median lactate level was 2.5 (0.80-15.3) mmol/L. Malignant arrhythmia, contrast induced nephropathy (CIN), and in-hospital mortality rates were not different between the high and low lactate groups. However, all-cause mortality was significantly higher in the high lactate group during the follow-up (p=0.005). Among all included parameters; lactate level [OR:1.76, (CI: 1.28-2.42); p<0.001] and age [OR:1.10, (CI: 1.03-1.17); p=0.004] were predictors for all-cause mortality. Admission lactate level can predict all-cause mortality in patients with STE-ACS. In addition, high admission lactate levels could help to raise more attention even if the patients have been discharged from the hospital. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Obstructive Sleep Apnea and Cardiovascular Disease: Where Do We Stand?
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Peker, Yüksel, Akdeniz, Bahri, Altay, Servet, Balcan, Baran, Başaran, Özcan, Baysal, Erkan, Çelik, Ahmet, Dursunoğlu, Dursun, Dursunoğlu, Neşe, Fırat, Selma, Gürkan, Canan Gündüz, Öztürk, Önder, Taşbakan, Mehmet Sezai, Aytekin, Vedat, İtil, Oya, Çuhadaroğlu, Çağlar, Atalar, Enver, and Yıldırır, Aylin
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SLEEP apnea syndromes ,CARDIOVASCULAR diseases ,CARDIOVASCULAR diseases risk factors ,DISEASE risk factors ,MEDICAL personnel - Abstract
Obstructive sleep apnea is common in adults with cardiovascular disease. Accumulating evidence suggests an association between obstructive sleep apnea and cardiovascular disease independent of the traditionally recognized cardiovascular disease risk factors. Observational studies indicate that obstructive sleep apnea is a risk factor for development of cardiovascular disease and that alleviation of obstructive events with positive airway pressure may improve cardiovascular disease outcomes. However, recent randomized controlled trials have not supported the beneficial effect of positive airway pressure in cardiac populations with concomitant obstructive sleep apnea. Some evidence suggests that the relationship between obstructive sleep apnea and traditionally recognized cardiovascular disease risk factors is bidirectional, suggesting that patients with cardiovascular disease may also develop obstructive sleep apnea and that efficient treatment of cardiovascular disease may improve obstructive sleep apnea. Recent data also indicate that the apnea-hypopnea index, which is commonly used as a diagnostic measure of obstructive sleep apnea severity, has limited value as a prognostic measure for cardiovascular disease outcomes. Novel markers of obstructive sleep apnea-associated hypoxic burden and cardiac autonomic response seem to be strong predictors of adverse cardiovascular disease outcomes and response to treatment of obstructive sleep apnea. This narrative review and position paper from the Turkish Collaboration of Sleep Apnea Cardiovascular Trialists aims to update the current evidence about the relationship between obstructive sleep apnea and cardiovascular disease and, consequently, raise awareness for health professionals who deal with cardiovascular and respiratory diseases to improve the ability to direct resources at patients most likely to benefit from treatment of obstructive sleep apnea and optimize treatment of the coexisting cardiovascular diseases. Moreover, the Turkish Collaboration of Sleep Apnea Cardiovascular Trialists aims to contribute to strengthening the efforts of the International Collaboration of Sleep Apnea Cardiovascular Trialists in this context. [ABSTRACT FROM AUTHOR]
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- 2023
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7. Relationship between thyroid function and carotid artery plaque ulceration
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Sevuk, Utkan, Bahadir, Mehmet Veysi, Altindag, Rojhat, Baysal, Erkan, Altintas, Bernas, Yaylak, Baris, Adiyaman, Mehmet Sahin, and Ay, Nurettin
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- 2015
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8. Selective right atrial cardioneuroablation in functional atrioventricular block
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Aksu, Tolga, Baysal, Erkan, Guler, Tumer Erdem, and Yalçn, Kçvanc
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- 2017
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9. Evaluation of cardiomyopathy with two‐dimensional speckle tracking echocardiography in limb‐girdle muscular dystrophy type 2A and 2B.
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Akyüz, Abdurrahman, Çap, Murat, Varsak, Süleyman, Işık, Ferhat, Turken, Askeri, Taştan, Ercan, and Baysal, Erkan
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Purpose: Cardiac involvement in limb‐girdle muscular dystrophy (LGMD)2A and LGMD2B, the most common subgroups of LGMD, is controversial. Our study aims to determine whether myocardial dysfunction develops in LGMD2A and LGMD2B patients. Methods: The study included 16 LGMD2A, 12 LGMD2B patients, and 48 healthy individuals. Comparisons included demographic, clinical, and laboratory parameters of LGMD2A and LGMD2B subgroups and traditional echocardiography and two‐dimensional speckle tracking echocardiography (2D‐STE) parameters with the normal population. Results: The median age was 33 (22–39 interquartile range [IQR]) in the LGMD2A group, 33 (27–38 IQR) in the LGMD2B group, and 28 (25–35 IQR) in the control group. The left ventricular (LV) ejection fraction of both LGMD2A and LGMD2B groups was similar to the control group (p = 0.296 and p = 0.918). Apical 4‐chamber longitudinal strain (LS), Apical 2‐chamber LS, Apical 3‐chamber LS, left ventricular global longitudinal strain (LVGLS)‐mid‐myocardial, LVGLS‐endocardium, and LVGLS‐epicardium were lower (less negative) in the LGMD2B group compared to the control group (p = 0.006, p = 0.001, p < 0.001, p < 0.001, p < 0.001, and p < 0.001, respectively). Conclusion: LV 2D‐STE parameters of LGMD2A patients were similar to the control group, while they decreased significantly (less negative) in LGMD2B patients, indicating that LV subclinical myocardial dysfunction may develop in LGMD2B patients. [ABSTRACT FROM AUTHOR]
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- 2022
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10. The association of serum albumin with coronary slow flow
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Cetin, Mustafa, Zencir, Cemil, Tasolar, Hakan, Baysal, Erkan, Balli, Mehmet, and Akturk, Erdal
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- 2014
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11. The effects of hyperoxaemia on tissue oxygenation in patients with a nadir haematocrit lower than 20% during cardiopulmonary bypass
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Altindag, Rojhat, Sevuk, Utkan, Baysal, Erkan, Yaylak, Baris, Adiyaman, Mehmet Sahin, Akkaya, Suleyman, Ay, Nurettin, and Alp, Vahhac
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- 2016
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12. The Effect of Hemodialysis on Electrocardiographic Parameters
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Astan, Ramazan, Akpinar, Ibrahim, Karan, Adnan, Kacmaz, Fehmi, Sokmen, Erdogan, Baysal, Erkan, Ozeke, Ozcan, and Selçuk, Mehmet Timur
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- 2015
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13. Evaluation of Myocardial Strain by 2-Dimensional Speckle Tracking Echocardiography in Patients with Facioscapulohumeral Muscular Dystrophy.
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Işık, Ferhat, Akyüz, Abdurrahman, Çap, Murat, Türken, Askeri, Varsak, Süleyman, and Baysal, Erkan
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SPECKLE tracking echocardiography ,FACIOSCAPULOHUMERAL muscular dystrophy ,ECHOCARDIOGRAPHY ,CONGENITAL disorders - Abstract
Background: Facioscapulohumeral muscular dystrophy is one of the most common congenital muscle disorders. Whether facioscapulohumeral muscular dystrophy causes cardiac involvement is still controversial. Although electrocardiography and conventional echocardiography studies have been performed, there is no data on strain echocardiography in facioscapulohumeral muscular dystrophy. Our study aims to compare the myocardial strain parameters by 2-dimensional speckle tracking echocardiography in patients with facioscapulohumeral muscular dystrophy and the normal group. Methods: This prospective single-center study included 35 patients with facioscapulohumeral muscular dystrophy and 54 control patients. Demographic, clinical, and laboratory parameters of both groups were compared. In addition to conventional echocardiography images, myocardial strain parameters were performed using 2-dimensional speckle tracking echocardiography. Results: The median age of the study population was 25 (19-35 IQR) and 51 (57.3%) of them were male. Left ventricle-global circumferential strain was significantly lower in the facioscapulohumeral muscular dystrophy group than in the normal group [-20.3 (-22.0; -19.0) vs. -21.6 (-22.5; -20.0), P = .020]. Two-dimensional speckle tracking echocardiography findings except left ventricle-global circumferential strain [for left ventricle-global longitudinal strain P = .259, for left ventricle-global radial strain P = .338, for right ventricle-global circumferential strain P = .250, and for right ventricle-free wall longitudinal strain P = .288] were similar in both groups. Conclusions: As a result of our study, there was no significant difference between 2-dimensional speckle tracking echocardiography parameters other than the left ventricle-global circumferential strain between facioscapulohumeral muscular dystrophy and normal groups. [ABSTRACT FROM AUTHOR]
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- 2022
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14. Increased Platelet Distribution Width Is Associated With ST-Segment Elevation Myocardial Infarction and Thrombolysis Failure
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Cetin, Mustafa, Murat Bakirci, Eftal, Baysal, Erkan, Tasolar, Hakan, Balli, Mehmet, Cakici, Musa, Abus, Sabri, Akturk, Erdal, and Ozgul, Sami
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- 2014
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15. Comparison of Fragmented Electrogram Based Strategy and High Frequency Stimulation for Detection of Ganglionated Plexi
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Aksu, Tolga, Baysal, Erkan, Lakkireddy, Dhanunjaya, Yalin, Kivanc, and Gopinathannair, Rakesh
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medicine.medical_specialty ,High frequency stimulation ,business.industry ,Internal medicine ,Cardiology ,Medicine ,Atrial fibrillation ,Case Report ,Cardiology and Cardiovascular Medicine ,business ,medicine.disease - Abstract
Ganglionated plexus (GP) ablation is an emerging technique in patients with cardioinhibitory vasovagal syncope and vagally mediated atrial fibrillation. Localization of GPs can be impacted by the technique used. A reproducible methodology for GP detection is needed to account for individual variations during electrophysiologic study. In this article, we aim to compare and contrast high-frequency stimulation vs. a fragmented electrogram guided strategy for GP localization.
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- 2020
16. Effects of de novo atrial fibrllation on prognosis in patients with STEMI.
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OKŞUL, Metin, ŞENER, Yusuf Ziya, CÖMERT, Adnan Duha, TÜZÜN, Rohat, SÖNER, Serdar, TAŞTAN, Ercan, GÜZEL, Tuncay, ALTUNBAŞ, Mahsum, ÖZTÜRK, Cansu, and BAYSAL, Erkan
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ATRIAL fibrillation treatment ,ST elevation myocardial infarction ,VENTRICULAR arrhythmia ,HEMORRHAGE ,KIDNEY diseases - Abstract
Background/Introduction: Atrial fibrillation occurs in the setting of ST-elevation myocardial infarction (STEMI) and it is associated with a worse prognosis. Purpose: We aimed to evaluate the effects of de novo AF development on cardiovascular outcomes in STEMI cases. Methods: We screened all of the STEMI cases between January 2018 and January 2021. Patients with de novo AF during hospitalization due to STEMI were compared with 1:1 propensity matched STEMI cases without AF. Results: A total of 68 patients were enrolled. Mean age of the study population was 65.5 ±11.5 years and vast majority of the patients were male (66.2%). Baseline characteristics were similar between the two groups and demonstrated in Table-1. Sustained ventricular arrhythmia rates were similar between the two groups (5.8& vs. 5.8%; p=1.000). Contrast induced nephropathy was more frequent in patients with AF, however it was not statistically significant (14.7% vs. 2.9%; p=0.197). Bleeding episodes were classified into major and minor bleeding according to the need of transfusion and presence of lifethreatening hemorrhage. Major bleeding was occured in only one case (Upper gastrointestinal bleeding) and minor bleeding rates were similar (14.7% vs. 5.8%; p=0.427). In-hospital mortality was distinctly higher in patients with AF, whereas it was not statistically significant (20.5% vs. 2.9%; p=0.054). Outcomes were summarized in Table-1. Conclusion(s): Contrast induced nephropathy, in-hospital mortality and bleeding rates are higher in STEMI patients with AF than counterparts despite it is not statistically significant. Larger sized studies will clarify the association between AF development and worse outcomes in STEMI patients. [ABSTRACT FROM AUTHOR]
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- 2023
17. Procedural and short‐term results of electroanatomic‐mapping‐guided ganglionated plexus ablation by first‐time operators: A multicenter study.
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Aksu, Tolga, De Potter, Tom, John, Leah, Osorio, Jose, Singh, David, Alyesh, Daniel, Baysal, Erkan, Kumar, Kapil, Mikaeili, Javad, dal Forno, Alexander, Yalin, Kivanc, Akdemir, Baris, Woods, Christopher E., Salcedo, Jonathan, Eftekharzadeh, Mahmoud, Akgun, Taylan, Sundaram, Sri, Aras, Dursun, Tzou, Wendy S., and Gopinathannair, Rakesh
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BRADYCARDIA treatment ,AUTONOMIC ganglia ,WORK experience (Employment) ,EVALUATION of medical care ,RESEARCH ,PILOT projects ,SYNCOPE ,TIME ,CATHETER ablation ,BODY surface mapping ,MEDICAL cooperation ,DISEASE relapse ,LONGITUDINAL method - Abstract
Introduction: Single‐center observational studies have shown promising results with fragmented electrogram (FE)‐guided ganglionated plexus (GP) ablation in patients with vagally mediated bradyarrhythmia (VMB). We aimed to compare the acute procedural characteristics during FE‐guided GP ablation in patients with VMB performed by first‐time operators and those of a single high‐volume operator. Methods and Results: This international multicenter cohort study included data collected over 2 years from 16 cardiac hospitals. The primary operators were classified according to their prior GP ablation experience: a single high‐volume operator who had performed > 50 GP ablation procedures (Group 1), and operators performing their first GP ablation cases (Group 2). Acute procedural characteristics and syncope recurrence were compared between groups. Forty‐seven consecutive patients with VMB who underwent FE‐guided GP ablation were enrolled, n = 31 in Group 1 and n = 16 in Group 2. The mean number of ablation points in each GP was comparable between groups. The ratio of positive vagal response during ablation on the left superior GP was higher in Group 1 (90.3% vs. 62.5%, p =.022). Ablation of the right superior GP increased heart rate acutely without any vagal response in 45 (95.7%) cases. The procedure time was longer in group 2 (83.4 ± 21 vs. 118.0 ± 21 min, respectively, p <.001). Over a mean follow‐up duration of 8.0 ± 3 months (range 2–24 months), none of the patients suffered from syncope. Conclusion: This multi‐center pilot study shows for the first time the feasibility of FE‐guided GP ablation across a large group of procedure‐naïve operators. [ABSTRACT FROM AUTHOR]
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- 2022
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18. Myocardial strain assessment by 2D speckle-tracking echocardiography in patients with congenital myopathy.
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Çap, Murat, Akyüz, Abdurrahman, Isik, Ferhat, Türken, Askeri, Erdogan, Emrah, Varsak, Süleyman, Burak, Cengiz, Süleymanoglu, Muhammed, and Baysal, Erkan
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- 2021
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19. Effects of permanent cardiac pacing on ventricular repolarization when compared to cardioneuroablation.
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Aksu, Tolga, Turagam, Mohit, Gautam, Sandeep, Futyma, Piotr, Akella, Krishna, Baysal, Erkan, Bozyel, Serdar, Yalin, Kivanc, Padmanabhan, Deepak, Shenthar, Jayaprakash, Natale, Andrea, Lakkireddy, Dhanunjaya, and Gopinathannair, Rakesh
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Introduction: The impact of cardioneuroablation (CNA) on ventricular repolarization by using corrected QT interval (QTc) measurements has been recently demonstrated. The effects of cardiac pacing (CP) on ventricular repolarization have not been studied in patients with vasovagal syncope (VVS). We sought to compare ventricular repolarization effects of CNA (group 1) with CP (group 2) in patients with VVS.Methods: We enrolled 69 patients with age 38 ± 13 years (53.6% male), n = 47 in group 1 and n = 22 in group 2. Clinical diagnosis of cardioinhibitory type was supported by cardiac monitoring or tilt testing. QTc was calculated at baseline (time-1), at 24 h after ablation (time-2), and at 9-12 months (time-3) in the follow-up.Results: In the group 1, from time-1 to time-2, a significant shortening in QTcFredericia (from 403 ± 27 to 382 ± 27 ms, p < 0.0001), QTcFramingham (from 402 ± 27 to 384 ± 27 ms, p < 0.0001), and QTcHodges (from 405 ± 26 to 388 ± 24 ms, p < 0.0001) was observed which remained lower than baseline in time-3 (373 ± 29, 376 ± 27, and 378 ± 27 ms, respectively). Although the difference between measurements in time-1 and time-2 was not statistically significant for QTcBazett, a significant shortening was detected between time-1 and time-3 (from 408 ± 30 to 394 ± 33, p = 0.005). In the group 2, there was no time-based changes on QTc measurements. In the linear mixed model analysis, the longitudinal reduction tendency in the QTcFredericia and QTcFramingham was more pronounced in group 1.Conclusions: Our results demonstrate that CNA reduces QTc levels through neuromodulation effect whereas CP has no effect on ventricular repolarization in patients with VVS. [ABSTRACT FROM AUTHOR]- Published
- 2021
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20. The relationship between coronary slow-flow and frontal QRS-T angle.
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Işık, Ferhat, Aslan, Burhan, Çap, Murat, Akyüz, Abdurrahman, İnci, Ümit, and Baysal, Erkan
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Objective: It is known that increased frontal QRS-T angle, which is a new ventricular repolarization marker is associated with adverse cardiac outcomes. It has been observed that the coronary slow-flow (CSF) phenomenon can cause arrhythmias and sudden cardiac death. The aim of our study is to investigate the relationship between CSF in patients and the frontal QRS-T angle.Material and Method: A total of 200 patients, 97 of who had CSF and 103 with the normal coronary flow (NCF), were included in our study. The CSF group was divided into two groups; single-vessel CSF and multi-vessel CSF. The TIMI-frame count was calculated from the coronary angiography images of each patient. 12-lead electrocardiography (ECG) records were examined. The frontal QRS-T angle was obtained from the automated reports of the ECG device.Results: The mean age of the study population was 50.7 ± 9.5 and 102 (51%) of patients were female. The frontal QRS-T angle was significantly higher in patients with CSF compared to the NCF group [48(31-64) vs 37(25-46), p = 0.001]. A positive correlation was observed between the frontal QRS-T angle and TIMI-frame count in the correlation analysis performed separately for LAD, Cx, RCA patients with CSF (respectively; r = 0.340 and p < 0.001, r = 0.262 and p = 0.002, r = 0.247 and p = 0.003). The frontal QRS-T angle was higher in patients with multi-vessel CSF than in patients with single-vessel CSF [53.5(41.5-76.5) vs 43.0(23.5-60.5), p = 0.039].Conclusion: There is a positive correlation between frontal QRS-T angle and TIMI-frame count. The frontal QRS-T angle is higher in patients with CSF. Also, frontal QRS-T angle was higher in the multi-vessel CSF group. [ABSTRACT FROM AUTHOR]- Published
- 2021
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21. Romatizmal Mitral Stenozu Olan Hastada Büyük Sol Atriyal Trombüs İçine Doğru Seyreden Koroner Arter Fistülü
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ALTINTAŞ, Bernas, ALTINTAŞ, Derya Deniz, BAYSAL, Erkan, and GÖKDENİZ, Tayyar
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Medicine ,Coronary artery fistula,left atrial thrombus,rheumatic mitral stenosis ,Koroner arter fistülü,sol atriyal trombüs,romatizmal mitral kapak darlığı ,Tıp - Abstract
Coronaryartery fistulae, which are connections between coronary artery branches andcardiac chambers or major vessels, are usually congenital forms of coronaryartery anomalies, but rarely may be acquired because of cardiac trauma,neovascularity in association with cardiac neoplasm, mural thrombus formation,or iatrogenic causes. Although half of the patients with coronary arteryfistula remain asymptomatic, these fistulae may lead to angina, syncope,congestive heart failure, myocardial infarction, and sudden death. Here wepresent a case of coronary artery fistula between right coronary artery andleft atrium through a large left atrial thrombus in a patient with rheumaticmitral stenosis. The diagnosis was confirmed using echocardiography,conventional and multislice computed tomography, and coronary angiography. Tothe best of our knowledge, this interesting and unique entity is the first tobe reported in the present literature., Koronerarter dalları ile kardiyak boşluklar veya büyük damarlar arasındaki normal dışıbağlantılar olan koroner arter fistülleri (KAF) genellikle koroner arter anomalilerininkonjenital formlarıdır. Fakat nadiren kardiyak travma, iyatrojenik nedenlerveya kardiyak neoplazm ve mural trombüs oluşumu ile ilişkilineovaskülarizasyona ikincil edinsel olabilir. KAF’ı olan hastaların yaklaşıkyarısının asemptomatik kalmasına rağmen bu fistüller anjina, senkop, konjestifkalp yetmezliği, miyokart infarktüsü ve ani ölüme yol açabilirler. Bu yazıdaromatizmal mitral kapak stenozu olan bir hastada sağ koroner arter (RCA) ilesol atriyum (LA) arasında, büyük LA trombüs içine açılan KAF’ı sunuyoruz. Tanı2 boyutlu ekokardiyografi, konvansiyonel koroner anjiyografi ve çok kesitlibilgisayarlı tomografik koroner anjiyografi kullanılarak doğrulandı. Bildiğimizkadarı ile bu ilginç ve benzersiz durum mevcut literatürde ilk defa raporlanmıştır.
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- 2017
22. The Association of Fractional Pulse Pressure with Acute Kidney Injury in Patients Undergoing Coronary Intervention due to ST-Segment Elevated Myocardial Infarction.
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Burak, Cengiz, Süleymanoğlu, Muhammed, Yesin, Mahmut, Cap, Murat, Yıldız, İbrahim, Rencüzoğulları, İbrahim, Çağdaş, Metin, Karabağ, Yavuz, Hamideyin, Şerif, İliş, Doğan, and Baysal, Erkan
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ACUTE kidney failure ,MYOCARDIAL infarction ,PERCUTANEOUS coronary intervention ,CORONARY angiography ,HOSPITAL mortality - Abstract
Objective: Acute kidney injury (AKI), which is prevalent in ST-segment elevated myocardial infarction (STEMI) patients who have undergone primary percutaneous coronary intervention (PCI), is associated with poor cardiovascular outcomes. As high pulse pressure (PP) is associated with adverse cardiovascular events, the present study's aim was to evaluate the relationship between fractional PP (PPf) and AKI in patients with STEMI who underwent primary PCI.Subjects and Methods: All laboratory findings as well as echocardiographic and angiographic data of 1,170 consecutive STEMI patients were retrospectively screened. PPf was calculated from the pressures invasively measured after sheath insertion and before performing coronary angiography.Results: From 1,170 eligible STEMI patients (mean age 56 years, 18.2% female), AKI developed in 143 (12.2%) patients. The PPf and pulsatility index were significantly higher in patients with AKI than those without (0.53 ± 0.10 vs. 0.61 ± 0.10, p < 0.001, and 0.80 ± 0.03 vs. 0.82 ± 0.03, p < 0.001, respectively). PPf was also found to be associated with AKI in univariable (OR 2.183, 95% CI 1.823-2.614, p< 0.001) and multivariable (OR 1.874, 95% CI 1.513-2.322, p < 0.001) analysis. In-hospital mortality was higher in patients with AKI than those without.Conclusion: Invasively measured PPf, which can be easily measured and has no additional cost in STEMI patients undergoing coronary intervention, is an independent predictor of AKI. In addition, PPf is superior to other blood pressure values and derivatives in AKI prediction. [ABSTRACT FROM AUTHOR]- Published
- 2020
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23. The effect of favipiravir on QTc interval in patients hospitalized with coronavirus disease 2019.
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Çap, Murat, Bilge, Önder, Işık, Ferhat, Burak, Cengiz, Karagöz, Ali, İnci, Ümit, Akyüz, Abdurrahman, Aslan, Burhan, Altıntaş, Bernas, Altındağ, Rojhat, Kaya, İlyas, Adıyaman, Mehmet Şahin, Süleymanoğlu, Muhammed, Kaya, Şafak, and Baysal, Erkan
- Abstract
Background: The effect of favipiravir on the QTc interval during the treatment of Coronavirus Disease 2019 (COVID-19) patients is unclear. Thus, the current study objective was to evaluate any change in the QTc interval in patients who were hospitalized due to COVID-19 receiving favipiravir treatment.Method: Patients hospitalized with COVID-19 were assessed in this single-center retrospective study. 189 patients, whose diagnosis was confirmed using real-time PCR, were included in the study. The patients were divided into three groups: those using hydroxychloroquine (Group 1, n = 66), hydroxychloroquine plus favipiravir (Group 2, n = 66), and favipiravir only (Group 3, n = 57). The QTc interval was measured before treatment (QTc-B) and 48 h after (i.e., the median) starting treatment (QTc-AT).Results: The median age was 53 (39-66 IQR) and 97 (51%) of patients were female. The median QTc(Bazett)-change was 7 ms (p = 0.028) and 12 ms (p < 0.001) and in Group 1 and 2, respectively. In Group 3, the median QTc(Bazett)-change was observed as -3 ms and was not statistically significant (p = 0.247). In multivariable analysis, while there was a significant relationship between QTc-AT(Bazett) and hydroxychloroquine (β coefficient = 2687, 95%CI 2599-16,976, p = 0,008), there was no significant relationship with favipiravir (β coefficient = 0,180, 95% CI -6435-7724, p = 0,858). Similarly, there was a significant relationship between the QTc-AT interval calculated using the Fredericia formula and hydroxychloroquine (β coefficient = 2120, 95% CI 0,514-14,398, p = 0,035), but not with favipiravir (β coefficient = 0,111, 95% CI -6450- 7221, p = 0,911).Conclusion: In the ECG recordings received in the following days after the treatment was started in COVID-19 patients, there was a significant prolongation in the QTc interval with hydroxychloroquine, but there was no significant change with favipiravir. [ABSTRACT FROM AUTHOR]- Published
- 2020
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24. Pregnancy-related atypical hemolytic uremic syndrome with renal, cardiac and obstetric complications and a satisfactory recovery: a case report.
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Gunay, Emrah, Ozan, Mahsum, Kaya, Seyhmus, Ocal, Ece, Kutlu, Zeynep, Senol, Ayhan, Danis, Ramazan, Baysal, Erkan, Kalin, Burhan Sami, Dincyurek, Huseyin Derya, and Demir, Cengiz
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HEMOLYTIC-uremic syndrome ,THROMBOTIC thrombocytopenic purpura ,HELLP syndrome ,COMPLEMENT factor H - Abstract
Improved renal recovery in patients with atypical hemolytic uremic syndrome following rapid initiation of eculizumab treatment. The presence of complement gene abnormalities is a risk for aHUS relapse after anti-C5 treatment discontinuation, including in P-aHUS patients. Dear Editor, A typical hemolytic uremic syndrome (aHUS), which occurs with the uncontrolled activity of the complement system, can occur at any age. When there is no haematological and renal improvement in the first four or five PEX treatments, the treatment should be based on the patient's ADAMTS-13 level. [Extracted from the article]
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- 2021
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25. Authors’ reply
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Kaya, Hakki, Kurt, Recep, Sevuk, Utkan, Bahadir, Mehmet Veysi, Altindag, Rojhat, Baysal, Erkan, Yaylak, Baris, Ay, Nurettin, Ayaz, Firat, Demirtas, Ertan, [Kaya, Hakki -- Kurt, Recep] Cumhuriyet Univ, Sch Med, Dept Cardiol, TR-58140 Kayseri Caddesi, Sivas, Turkey, and Sevuk, Utkan -- 0000-0001-7429-5997
- Subjects
medicine.medical_specialty ,Chemical Health and Safety ,Multivariate analysis ,Letter ,medicine.diagnostic_test ,Therapeutics and Clinical Risk Management ,business.industry ,Complete blood count ,General Medicine ,medicine.disease ,Pulmonary embolism ,Surgery ,Venous thrombosis ,Erythrocyte maturation ,Heart failure ,Internal medicine ,medicine ,Cardiology ,Pharmacology (medical) ,In patient ,General Pharmacology, Toxicology and Pharmaceutics ,Mean platelet volume ,business ,Safety Research - Abstract
WOS: 000364300100001, PubMed ID: 26609235, …
- Published
- 2015
26. Catheter Ablation of Atrioventricular Block: From Diagnosis to Selection of Proper Treatment
- Author
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Baysal, Erkan, Guler, Tumer Erdem, Gopinathannair, Rakesh, Bozyel, Serdar, Yalin, Kıvanc, and Aksu, Tolga
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- 2020
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27. Relationship Between Elevated HbA1c and Deep Sternal Wound Infection in Patients Undergoing Cardiac Surgery
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SEVÜK, Utkan, BİLGİÇ, Abdulkadir, YAYLAK, Barış, AY, Nurettin, BAYSAL, Erkan, ERKUL, Aylin, ALP, Vahhaç, BEYAZIT, Ünal, and AKKAYA, Süleyman
- Subjects
Mediastinit,koroner arter baypas cerrahisi,hemoglobin A1c,diabetes mellitus,derin sternal yara infeksiyonu ,Medicine ,Mediastinitis,coronary artery bypass grafting,hemoglobin A1c,diabetes mellitus,deep sternal wound infection ,Tıp - Abstract
Giriş:Kalp cerrahisi yapılan hastalarda, diabetesmellitus (DM)’lu hastalarda olduğu kadar diyabetik olmayan hastalarda dahiperglisemi ile sık karşılaşılır. Kalp cerrahisi sonrasında intraoperatif vepostoperatif hipergliseminin derin sternal yara infeksiyonu (DSYİ) içinbağımsız risk faktörü olduğu gösterilmiştir. Ancak, preoperatif kronik glisemikkontrolün DSYİ ile ilişkisi tartışmalıdır. Hemoglobin A1c (HbA1c) geçmiş 2-3aylık dönemdeki glukoz düzeyi hakkında bilgi verir. Bu çalışmanın amacı koronerbaypas cerrahisi yapılan DM’li hastalarda, HbA1c seviyeleri ile DSYİ arasındakiilişkiyi incelemektir.Hastalarve Yöntem: Kliniğimizde kardiyopulmonerbaypas altında koroner baypas operasyonu yapılmış olan hastaların kayıtlarıretrospektif olarak incelendi. DM’si olan ve perioperatif periyodda yeterliglisemik kontrol sağlanmış 180 hasta çalışmaya dahil edildi. DM’si olmayankoroner baypas cerrahisi yapılmış ardışık 200 hasta kontrol grubuna dahiledildi.Bulgular:Medyan HbA1c değerleri diyabetik hasta grubunda anlamlıolarak daha yüksekti [8.16 (7.2-10.4 vs 5.49 (5-6), p< 0.001]. DSYİ sıklığıbakımdan iki grup arasında istatistiksel olarak anlamlı bir fark saptanmadı [%5(n= 9) vs %2 (n= 4); p= 0.1]. Yoğun bakımda kalış (p= 0.005) ve hastanede kalışsüreleri (p= 0.01) diyabetik hastalarda anlamlı olarak daha uzundu.Sonuç: Preoperatif dönemdeki yüksek HbA1cseviyeleri koroner baypas sonrası DSYİ ile ilişkili bulunmamıştır. Ayrıcaperioperatif periyodda yeterli glisemik kontrol sağlanmış DM’li hastalarda DSYİ sıklığında artış olmadığı saptanmıştır., Introduction:Hyperglycemia is common in patients with andwithout diabetes mellitus (DM) following cardiac surgery. Intra- andpostoperative hyperglycemia has been shown to be an independent risk factor fordeep sternal wound infection (DSWI) after cardiac surgery. However, whether thepreoperative chronic glycemic control is associated with the risk of DSWI remainscontroversial. Hemoglobin A1c (HbA1c) provides a measure of glucose controlover the prior 2-3 months. The aim of this study was to evaluate therelationship between preoperative HbA1c levels and DSWI in patients with DMundergoing coronary artery bypass grafting (CABG).Patientsand Methods: Records of patients who underwent electiveon-pump CABG were retrospectively reviewed. A total of 180 patients with DMwere included in the study. Patients were excluded if their blood glucoselevels were not adequately controlled in the perioperative period. A total of200 consecutive patients without DM were taken as controls.Results:Median HbA1c levels were significantly higher inpatients with DM [8.16 (7.2-10.4)] than in controls [5.49 (5-6)] (p< 0.001).There was no significant difference in DSWI incidence between patients with DMand controls [5% (n= 9) vs. 2% (n= 4); P= 0.1]. Hospital (p= 0.01) andintensive care unit stays (p= 0.005) were significantly longer in patients withDM.Conclusion: We found that DSWI was notassociated with preoperative HbA1c levels in patients undergoing CABG. Inaddition, with adequate glycemic control in the perioperative period, our studydemonstrated no significant difference with regard to DSWI between patientswith DM and controls.
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- 2016
28. Prolonged P wave peak time is associated with the severity of coronary artery disease in patients with non-ST segment elevation myocardial infarction.
- Author
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Burak, Cengiz, Yesin, Mahmut, Tanık, Veysel Ozan, Çağdaş, Metin, Rencüzoğulları, İbrahim, Karabağ, Yavuz, Hamideyin, Şerif, İliş, Doğan, Çınar, Tufan, Altıntaş, Bernas, and Baysal, Erkan
- Abstract
Background: Multi-vessel coronary artery disease (CAD) is associated with worse outcome in non-ST segment elevation myocardial infarction (NSTEMI) patients. Depending on the severity of CAD, there may be prolongation of atrial depolarization time as a result of left ventricular dysfunction and atrial ischemia. Therefore, we aimed to study whether the severity of CAD can be predicted with the P wave peak time (PWPT) in the electrocardiography (ECG) obtained during the diagnosis in NSTEMI patients.Method: A total of 162 patients were included. The coronary angiography records of all patients were analyzed and SYNTAX scores were calculated. Patients were divided into two groups, according to CAD severity. In addition to well-known P wave parameters, PWPT, defined as the time from the beginning of the P wave to its peak, was measured in the leads DII and V1.Results: The PWPTs in the leads DII and V1 were significantly longer in the group with severe CAD (71 ± 13 vs. 61 ± 12, p < 0.001, 63 ± 24 vs. 53 ± 18, p = 0.024, respectively). PWPT was found to be an independent predictor of severe CAD and the best cut-off value of PWPT in the lead DII was 69.6 ms with sensitivity of 58.3% and specificity of 78.9%.Conclusion: Our findings show that prolonged PWPT, which is a parameter easily obtainable from the ECG, is associated with severe CAD. Recognition of NSTEMI patients with severe CAD at the time of diagnosis before performing coronary angiography may be important for the planning of treatment. [ABSTRACT FROM AUTHOR]- Published
- 2019
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29. Evaluation of myocardial dispersion of repolarization in patients with heart transplantation.
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BURAK, Cengiz, BAYSAL, Erkan, SÜLEYMANOĞLU, Muhammed, YAYLA, Çağrı, CAY, Serkan, and KERVAN, Ümit
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MYOCARDIAL infarction , *ELECTROCARDIOGRAPHY , *HEART transplantation , *CORONARY disease , *CARDIOVASCULAR diseases - Abstract
Background/aim: The number of patients with heart transplantation has dramatically increased in the last decade. Considerable studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. We analyzed the dispersion of myocardial repolarization using electrocardiographic Tp-e interval and Tp-e/QTc ratio in patients with heart transplantation. Materials and methods: This observational study included 38 patients (12 female and 26 male) with heart transplantation and 38 wellmatched controls. From electrocardiograms, Tp-e interval and Tp-e/QTc ratio were calculated and compared between the 2 groups. Results: Noninvasive arrhythmia indicators including Tp-e interval (84.63 ± 14.17 ms vs 71.82 ± 7.47 ms, P < 0.001), Tp-e/QTc ratio (0.19 ± 0.04 vs 0.16 ± 0.02, P < 0.001) and QTc interval except QT interval were significantly higher in transplanted hearts compared to normal hearts. Conclusion: Patients with heart transplantation have increased myocardial dispersion of repolarization. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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30. OP-568 - Relation between Monocyte/High Density Lipoprotein Ratio Acute Ischemic Stroke Severity
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Ozturk, Onder, Ozturk, Unal, Nergiz, Sebnem, Altıntaş, Bernas, and Baysal, Erkan
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- 2018
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31. Relationship between fragmented QRS complexes in leads V4-V6 and left ventricular apical thrombus formation in patients presenting with first acute anterior myocardial infarction.
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Baysal, Erkan, Burak, Cengiz, Yaylak, Barış, Altıntaş, Bernas, Öztürk, Önder, Çiftçi, Hacı, Altındağ, Rojhat, and Söner, Serdar
- Abstract
Copyright of Archives of the Turkish Society of Cardiology / Türk Kardiyoloji Derneği Arşivi is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
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32. Determination and mapping of cadmium accumulation in plant leaves on the highway roadside, Turkey.
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Çolak, Merve, Gümrükçüoğlu, Mahnaz, Boysan, Füsun, and Baysal, Erkan
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CADMIUM content of plants ,BIOACCUMULATION in plants ,DEIONIZATION of water ,INDUCTIVELY coupled plasma mass spectrometry ,EMISSION inventories - Abstract
This study investigates cadmium (Cd) accumulation in the plant leaves of juglans regia (walnut) and cydonia oblanga (quince) trees related to traffic emissions on the highway roadside. The plant leaf samples were collected from 20 sites on the D-100 Highway roadside and washed with deionized water before analyzed. Determination of Cd was carried out using an inductively-coupled plasma-mass spectrometer after microwave digestion of the samples. Cd concentration on the plant leaves was found to be between 0.04-0.11 mg/kg. In order to determine the traffic-based emissions, vehicles were counted and an emission inventory was prepared. 0.18 tons of Cd was found to be delivered into the atmosphere every day. Cd accumulation depends on traffic density because there were no residential area and industrial plants. The distribution of Cd accumulation caused by traffic emissions was mapped by using a geographic information system (GIS). The maps showed that the Cd accumulation was high in the areas near the highway and then gradually decreased by moving away from the highway. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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33. PP-100 Left Ventricular Apical Thrombus Formation Following Acute Myocardial Infarction In A Patient Under Dabigatran Treatment
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Altıntaş, Bernas, Yaylak, Barış, Baysal, Erkan, Deniz, Derya, Ede, Hüseyin, and Bilge, Önder
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- 2016
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34. The effects of hyperoxaemia on tissue oxygenation in patients with a nadir haematocrit lower than 20% during cardiopulmonary bypass.
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Sevuk, Utkan, Altindag, Rojhat, Baysal, Erkan, Yaylak, Baris, Adiyaman, Mehmet Sahin, Akkaya, Suleyman, Ay, Nurettin, and Alp, Vahhac
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ACTIVE oxygen in the body ,ANEMIA ,BLOOD gases analysis ,CARDIOPULMONARY bypass ,CHI-squared test ,CONFIDENCE intervals ,HEMATOCRIT ,LACTATES ,MULTIVARIATE analysis ,PERFUSION ,STATISTICS ,T-test (Statistics) ,LOGISTIC regression analysis ,HYPEROXIA ,RETROSPECTIVE studies ,DATA analysis software ,ODDS ratio ,MANN Whitney U Test - Abstract
Excessive haemodilution and the resulting anaemia during CPB is accompanied by a decrease in the total arterial oxygen content, which may impair tissue oxygen delivery. Hyperoxic ventilation has been proven to improve tissue oxygenation in different pathophysiological states of anaemic tissue hypoxia. The aim of this study was to examine the influence of arterial hyperoxaemia on tissue oxygenation during CPB. Records of patients undergoing isolated CABG with CPB were retrospectively reviewed. Patients with nadir haematocrit levels below 20% during CPB were included in the study. Tissue hypoxia was defined as hyperlactataemia (lactate >2.2 mmol/L) coupled with low ScVO
2 (ScVO2 <70%) during CPB. One hundred patients with normoxaemia and 100 patients with hyperoxaemia were included in the study. Patients with hyperoxaemia had lower tissue hypoxia incidence than patients with normoxaemia (p<0.001). Compared with patients without tissue hypoxia, patients with tissue hypoxia had significantly lower PaO2 values (p<0.001) and nadir haematocrit levels (p<0.001). Nadir haematocrit levels <18% (OR: 5.3; 95% CI: 2.67–10.6; p<0.001) and hyperoxaemia (OR: 0.28; 95% CI: 0.14–0.56; p<0.001) were independently associated with tissue hypoxia. Conclusions: Hyperoxaemia during CPB may be protective against tissue hypoxia in patients with nadir haematocrit levels <20%. [ABSTRACT FROM AUTHOR]- Published
- 2016
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35. Neutrophil/lymphocyte ratio is associated with right ventricular dysfunction in patients with acute inferior ST-segment elevation myocardial infarction.
- Author
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Yaylak, Barıs, Ede, Huseyin, Baysal, Erkan, Altıntas, Bernas, Akyuz, Sukru, Sevuk, Utkan, Erdoğan, Guney, Comert, Nuri, Cakmak, Ender Ozgun, Altındag, Rojhat, Karahan, Zulkuf, Bilge, Onder, and Cevik, Kemal
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- 2016
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36. Impact of Coronary Collateral Circulation on In-Hospital Death in Patients with Inferior ST Elevation Myocardial Infarction.
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Yaylak, Baris, Altintas, Bernas, Ede, Huseyin, Baysal, Erkan, Akyuz, Sukru, Bilge, Onder, Sevuk, Utkan, Erdogan, Guney, and Ciftci, Haci
- Abstract
Objectives. Coronary collateral circulation (CCC) may limit the size of right ventricular (RV) infarcts but does not fully explain the relationship between CCC and clinical adverse events in patients with inferior STEMI. In this study, it was aimed to assess the relationship between preintervention angiographic evidence of CCC and clinical outcomes in patients with inferior STEMI who have undergone percutaneous coronary intervention. Methods. A total of 235 inferior STEMI patients who presented within the first 12 hours from the symptom onset were included. CCC to the right coronary artery (RCA) before angioplasty were angiographically assessed, establishing two groups: 147 (63%) patients without CCC and 88 (37%) with CCC according to presence of CCC. Results. RV infarction, complete atrioventricular block, VT/VF, cardiogenic shock, and in-hospital death were noted less frequently in patients with CCC than in those without CCC. Absence of CCC to RCA was found to be the independent predictor for in-hospital death among them (odds ratio 4.0, 95% CI 1.8–12.6; p=0.03). Conclusion. Presence of angiographically detectable CCC was associated with better in-hospital outcomes including RV infarction, complete AV block, cardiogenic shock, and VT/VF in patients with inferior STEMI. [ABSTRACT FROM AUTHOR]
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- 2015
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37. Relationship between cobalamin deficiency and delirium in elderly patients undergoing cardiac surgery.
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Sevuk, Utkan, Baysal, Erkan, Ay, Nurettin, Altas, Yakup, Altindag, Rojhat, Yaylak, Baris, Alp, Vahhac, and Demirtas, Ertan
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- *
VITAMIN B12 deficiency , *DELIRIUM , *MENTAL health of older people , *HEALTH of older people , *COGNITION disorders - Abstract
Background: Delirium is common after cardiac surgery and is independently associated with increased morbidity, mortality, prolonged hospital stays, and higher costs. Cobalamin (vitamin B12) deficiency is a common cause of neuropsychiatric symptoms and affects up to 40% of elderly people. The relationship between cobalamin deficiency and the occurrence of delirium after cardiac surgery has not been examined in previous studies. We examined the relationship between cobalamin deficiency and delirium in elderly patients undergoing coronary artery bypass grafting (CABG) surgery. Material and methods: A total of 100 patients with cobalamin deficiency undergoing CABG were enrolled in this retrospective study. Control group comprised 100 patients without cobalamin deficiency undergoing CABG. Patients aged 65 years or over were included. Diagnosis of delirium was made using Intensive Care Delirium Screening Checklist. Delirium severity was measured using the Delirium Rating Scale-revised-98. Results: Patients with cobalamin deficiency had a significantly higher incidence of delirium (42% vs 26%; P=0.017) and higher delirium severity scores (16.5±2.9 vs 15.03±2.48; P=0.034) than patients without cobalamin deficiency. Cobalamin levels were significantly lower in patients with delirium than patients without delirium (P=0.004). Delirium severity score showed a moderate correlation with cobalamin levels (ρ=-0.27; P=0.024). Logistic regression analysis demonstrated that cobalamin deficiency was independently associated with postoperative delirium (OR 1.93, 95% CI 1.03-3.6, P=0.038). Conclusion: The results of our study suggest that cobalamin deficiency may be associated with increased risk of delirium in patients undergoing CABG. In addition, we found that preoperative cobalamin levels were associated with the severity of delirium. This report highlights the importance of investigation for cobalamin deficiency in patients undergoing cardiac surgery, especially in the elderly. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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38. Predictors of atrial fibrillation recurrence after cryoballoon ablation.
- Author
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Aksu, Tolga, Baysal, Erkan, Guler, Tümer Erdem, Golcuk, Sukriye Ebru, Erden, İsmail, and Ozcan, Kazim Serhan
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- *
ATRIAL fibrillation treatment , *ABLATION techniques , *PULMONARY veins , *ERYTHROCYTES , *PAROXYSMAL hemoglobinuria - Abstract
Objective: Cryoballoon ablation (CA) is a safe and efficient method for pulmonary vein isolation in the treatment of paroxysmal atrial fibrillation (AF). There are conflicting results about the predictors of AF recurrence. The aim of this study is to evaluate the role of hematological indices to predict AF recurrence after CA. Methods: A total of 49 patients (mean age 58.3±12.2 years, 51.02% female) with symptomatic paroxysmal AF underwent CA procedure. One hundred and sixty-eight pulmonary veins were used for pulmonary vein isolation with the second-generation cryoballoon. The hematological samples were obtained before and 24 hours after ablation. Results: At a mean follow-up of 10.2±2.4 months, the probability of being arrhythmia-free after a single procedure was 86%. Patients with AF recurrence had higher red cell distribution width levels (16.10%±1.44% vs 14.87%±0.48%, P=0.035). The neutrophil/lymphocyte ratio, erythrocyte sedimentation rate, and C-reactive protein levels were detected in the patients with or without recurrence. Left atrial diameter (46.28±4.30 mm vs 41.02±4.10 mm, P=0.002), duration of AF (6.71±4.57 years vs 3.59±1.72 years, P=0.003), and age (65.01±15.39 years vs 54.29±11.32 years, P=0.033) were the other independent predictors of clinical recurrence after CA. Multiple regression analysis revealed that left atrial diameter was the only independent predictor for AF recurrence (P=0.012). Conclusion: In this study of patients with paroxysmal AF undergoing cryoablation, increased preablation red cell distribution width levels, and not C-reactive protein or erythrocyte sedimentation rate, was associated with a higher rate of AF recurrence. Our results support the role of a preablation, proinflammatory, and pro-oxidant environment in the development of AF recurrence after ablation therapy but suggest that other factors are also important. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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39. Role of diclofenac in the prevention of postpericardiotomy syndrome after cardiac surgery.
- Author
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Sevuk, Utkan, Baysal, Erkan, Altindag, Rojhat, Yaylak, Baris, Adiyaman, Mehmet Sahin, Ay, Nurettin, Alp, Vahhac, and Beyazit, Unal
- Subjects
DICLOFENAC ,ANTI-inflammatory agents ,POSTPERICARDIOTOMY syndrome ,HEART diseases ,AUTOIMMUNE diseases ,ANALGESIA - Abstract
Objective: Postpericardiotomy syndrome (PPS), which is thought to be related to autoimmune phenomena, represents a common postoperative complication in cardiac surgery. Late pericardial effusions after cardiac surgery are usually related to PPS and can progress to cardiac tamponade. Preventive measures can reduce postoperative morbidity and mortality related to PPS. In a previous study, diclofenac was suggested to ameliorate autoimmune diseases. The aim of this study was to determine whether postoperative use of diclofenac is effective in preventing early PPS after cardiac surgery. Methods: A total of 100 patients who were administered oral diclofenac for postoperative analgesia after cardiac surgery and until hospital discharge were included in this retrospective study. As well, 100 patients undergoing cardiac surgery who were not administered nonsteroidal anti-inflammatory drugs were included as the control group. The existence and severity of pericardial effusion were determined by echocardiography. The existence and severity of pleural effusion were determined by chest X-ray. Results: PPS incidence was significantly lower in patients who received diclofenac (20% vs 43%) (P<0.001). Patients given diclofenac had a significantly lower incidence of pericardial effusion (15% vs 30%) (P=0.01). Although not statistically significant, pericardial and pleural effusion was more severe in the control group than in the diclofenac group. The mean duration of diclofenac treatment was 5.11±0.47 days in patients with PPS and 5.27±0.61 days in patients who did not have PPS (P=0.07). Logistic regression analysis demonstrated that diclofenac administration (odds ratio [OR] 0.34, 95% confidence interval [CI] 0.18-0.65, P=0.001) was independently associated with PPS occurrence. Conclusion: Postoperative administration of diclofenac may have a protective role against the development of PPS after cardiac surgery. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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- View/download PDF
40. How urgent are cases brought to the emergency department by ambulance?
- Author
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Yuksel, Melih, Saglam, Caner, Çakmak, Muharrem, Baysal, Erkan, Altunbay, Aynur, and Baran, Sultan
- Subjects
HOSPITAL emergency services ,AMBULANCE service ,HOSPITAL observation units ,TRAUMA centers ,ADVANCED trauma life support - Abstract
Copyright of Journal of Clinical & Experimental Investigations is the property of Modestum Publications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
- Full Text
- View/download PDF
41. The neutrophil to lymphocyte ratio is associated with severity of rheumatic mitral valve stenosis.
- Author
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Baysal, Erkan, Burak, Cengiz, Cay, Serkan, Aksu, Tolga, Altıntaş, Bernas, Yaylak, Barış, Sevük, Utkan, and Bilge, Önder
- Subjects
- *
NEUTROPHILS , *GRANULOCYTES , *LYMPHOCYTES , *LEUCOCYTES , *MITRAL valve - Abstract
Background: Rheumatic heart disease (RHD) is a serious health concern in developing countries. Rheumatic mitral stenosis (RMS) is the most long-term sequel in RHD. The neutrophil to lymphocyte ratio (NLR) is a novel marker, and a higher NLR has been associated with poor clinical outcomes in various cardiovascular disorders. We evaluated the availability of NLR to predict severity of mitral stenosis (MS) in patients with RHD. Methods: We analyzed 300 consecutive patients with RMS. The patients were divided into tertiles according to NLR: 0.85< NLR ⩽1.85 (n=100, tertile 1), 1.86⩽ NLR ⩽2.46 (n=100, tertile 2), and 2.47⩽ NLR ⩽7.08 (n=100, tertile 3). Patients with RMS were divided into three groups based on the degree of MS as mild, moderate, and severe MS. After the initial evaluation, 187 patients with moderate-to-severe RMS (Group 1) and 113 patients with mild RMS (Group 2) were reassessed. Results: The patients with severe RMS had significantly elevated NLR, mean platelet volume, and pulmonary artery systolic pressure values compared to patients with moderate and mild MS (P<0.001, P<0.001, P<0.001 respectively). Multivariate binary logistic regression analysis revealed that high levels of NLR was an independent predictor of severe RMS (odds ratio =0.68, P=0.008). Moderate-to-severe RMS incidence was significantly higher among patients in the tertile 3 (odds ratio =2.8, P=0.001). Conclusion: NLR is a new inflammatory marker and a simple, rapid, and easily accessible prognostic parameter that can be associated with severity of RMS in patients with RHD. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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42. Roles of the red cell distribution width and neutrophil/lymphocyte ratio in predicting thrombolysis failure in patients with an ST-segment elevation myocardial infarction.
- Author
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Baysal, Erkan, Çetin, Mustafa, Yaylak, Bariş, Altintaş, Bernas, Altındağ, Rojhat, Adıyaman, Şahin, Altaş, Yakup, Kaya, İlyas, and Sevuk, Utkan
- Published
- 2015
- Full Text
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43. Intracoronary epinephrine in the treatment of refractory no-reflow after primary percutaneous coronary intervention: a retrospective study.
- Author
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Aksu, Tolga, Guler, Tumer Erdem, Colak, Ayse, Baysal, Erkan, Durukan, Mine, Sen, Taner, and Guray, Umit
- Subjects
ADRENALINE ,CORONARY arteries ,BRONCHODILATOR agents ,HEART blood-vessels ,PATIENTS - Abstract
Background: Despite the advances in medical and interventional treatment modalities, some patients develop epicardial coronary artery reperfusion but not myocardial reperfusion after primary percutaneous coronary intervention (PCI), known as no-reflow. The goal of this study was to evaluate the safety and efficacy of intracoronary epinephrine in reversing refractory no-reflow during primary PCI. Methods: A total of 248 consecutive STEMI patients who had undergone primary PCI were retrospectively evaluated. Among those, 12 patients which received intracoronary epinephrine to treat a refractory no-reflow phenomenon were evaluated. Refractory no-reflow was defined as persistent TIMI flow grade (TFG) ⩽2 despite intracoronary administration of at least one other pharmacologic intervention. TFG, TIMI frame count (TFC), and TIMI myocardial perfusion grade (TMPG) were recorded before and after intracoronary epinephrine administration. Results: A mean of 333 ± 123 mcg of intracoronary epinephrine was administered. No-reflow was successfully reversed with complete restoration of TIMI 3 flow in 9 of 12 patients (75%). TFG improved from 1.33 ± 0.49 prior to epinephrine to 2.66 ± 0.65 after the treatment (p < 0.001). There was an improvement in coronary flow of at least one TFG in 11 (93%) patients, two TFG in 5 (42%) cases. TFC decreased from 56 ± 10 at the time of no-reflow to 19 ± 11 (p < 0.001). A reduction of TMPG from 0.83 ± 0.71 to 2.58 ± 0.66 was detected after epinephrine bolus (p < 0.001). Epinephrine administration was well tolerated without serious adverse hemodynamic or chronotropic effects. Intracoronary epinephrine resulted in significant but tolerable increase in heart rate (68 ± 13 to 95 ± 16 beats/min; p < 0.001) and systolic blood pressure (94 ± 18 to 140 ± 20; p < 0.001). Hypotension associated with no-reflow developed in 5 (42%) patients. During the procedure, intra-aortic balloon pump counterpulsation was required in two (17%) patients, transvenous pacing in 2 (17%) cases, and both intra-aortic balloon counterpulsation and transvenous pacing in one (8%) patients. One patient (8%) died despite all therapeutic measures. Conclusion: Intracoronary epinephrine may become an effective alternative in patients suffering refractory no-reflow following primary PCI. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
44. Relationship between Nadir Hematocrit during Cardiopulmonary Bypass and Postoperative Hyperglycemia in Nondiabetic Patients.
- Author
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Sevuk, Utkan, Cakil, Nevzat, Altindag, Rojhat, Baysal, Erkan, Altintas, Bernas, Yaylak, Baris, Adiyaman, Mehmet Sahin, and Bahadir, Mehmet Veysi
- Published
- 2014
- Full Text
- View/download PDF
45. An adult case of single atrium diagnosed using three-dimensional echocardiography.
- Author
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Altıntaş, Bernas, Yaylak, Barış, and Baysal, Erkan
- Subjects
DYSPNEA ,PALPITATION ,PULMONARY hypertension ,ATRIAL fibrillation ,CALCIUM antagonists - Abstract
The article presents a case study of 43-year-old woman with dyspnea and palpitation.. Examination revealed presence of right ventricular enlargement along with severe pulmonary hypertension, atrial fibrillation, and absence of interatrial septum (IAS). Patient was treated with bosentan and furosemid and calcium channel blocker and attend attained New York Heart Association functional class I–II.
- Published
- 2017
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46. Hemogram parameters for predicting pulmonary embolism in patients with deep venous thrombosis.
- Author
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Kaya, Hakki, Kurt, Recep, Sevuk, Utkan, Bahadir, Mehmet Veysi, Altindag, Rojhat, Baysal, Erkan, Yaylak, Baris, Ay, Nurettin, Ayaz, Firat, and Demirtas, Ertan
- Subjects
BLOOD platelet examination ,PULMONARY embolism ,DIAGNOSIS - Abstract
A letter to the editor is presented in response to the article "Value of serial platelet indices measurements for the prediction of pulmonary embolism in patients with deep venous thrombosis" by U. Sevuk and colleagues in the August 2015 issue along with the author's reply.
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- 2015
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47. Massive, ring-shaped pericardial calcification of atrioventricular groove.
- Author
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Altıntaş, Bernas, Deniz, Derya, Altındağ, Rojhat, Yaylak, Barış, Baysal, Erkan, and Bilge, Önder
- Subjects
CORONARY disease ,DIAGNOSIS ,CORONARY angiography ,CORONARY artery bypass - Abstract
The article presents a case study of a 72-year-old man who was treated for pericardial calcification of atrioventricular (AV) groove and constrictive physiology of tricuspid and mitral valve. Topics include the diagnosis of acute coronary syndrome, the interpretation of the patient's coronary angiography result, and the treatment through coronary artery by-pass graft surgery and pericardial resection.
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- 2017
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48. The effect of ticagrelor based dual antiplatelet therapy on development of late left ventricular thrombus after acute anterior ST elevation myocardial infarction.
- Author
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Altıntaş, Bernas, Altındağ, Rojhat, Bilge, Önder, Baysal, Erkan, Öztürk, Önder, Yaylak, Barış, Ede, Hüseyin, Karahan, Mehmet Zülkif, Burak, Cengiz, and Tanboğa, İbrahim Halil
- Subjects
- *
MYOCARDIAL infarction , *THROMBOSIS , *MAXIMUM likelihood statistics , *BODY mass index , *LOGISTIC regression analysis - Abstract
The aim of this study is to investigate the impact of ticagrelor as compared to clopidogrel based dual antiplatelet therapy (DAPT) during post-discharge management on the incidence of left ventricular (LV) thrombus in patients with first acute anterior ST elevation myocardial infarction (STEMI). 641 patients who met the inclusion criteria were divided into two groups based on the receipt of either ticagrelor or clopidogrel based DAPT. Left ventricular thrombus was detected in 73 (11.4%) patients at the first month echocardiographic examination. Ticagrelor based DAPT was associated with significantly less incidence of LV thrombus when compared to clopidogrel [20 (7.4%) vs 53 (14.0%) OR: 0.50 (0.29–0.86)]. Penalized maximum likelihood estimation (PMLE) logistic regression analyses were performed to fourteen candidate variables for identifying the independent predictors of LV thrombus, ticagrelor (compared with clopidogrel) [OR: 0.53 (0.28–0.96), p = 0.039], body mass index (BMI) [OR: 0.58 (0.44–0.77), p < 0.001], KILLIP class (I vs II–IV) [OR: 0.35 (0.14–0.83), p = 0.017], age [OR: 1.22 (1.08–1.40), p < 0.001], poor postprocedural myocardial blush grade (MBG) [OR: 3.35 (1.32–8.15), p = 0.012] and LVEF predischarge [OR: 0.79 (0.72–0.86), p < 0.001] were found to be associated with LV thrombus. Our study demonstrated that the incidence of LV trombus was significantly lower with ticagrelor than clopidogrel-based DAPT during postdischarge treatment for anterior STEMI patients. • Left ventricular thrombus is a potential source of systemic embolization after STEMI. • Prophylactic treatment in addition to DAPT is not recommended after discharge. • Ticagrelor has faster and achieves more consistent P2Y12 inhibition than clopidogrel. • The incidence of left ventricular thrombus is lower with ticagrelor than clopidogrel. [ABSTRACT FROM AUTHOR]
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- 2019
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49. Comparison of Fragmented Electrogram Based Strategy and High Frequency Stimulation for Detection of Ganglionated Plexi.
- Author
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Aksu T, Baysal E, Lakkireddy D, Yalin K, and Gopinathannair R
- Abstract
Ganglionated plexus (GP) ablation is an emerging technique in patients with cardioinhibitory vasovagal syncope and vagally mediated atrial fibrillation. Localization of GPs can be impacted by the technique used. A reproducible methodology for GP detection is needed to account for individual variations during electrophysiologic study. In this article, we aim to compare and contrast high-frequency stimulation vs. a fragmented electrogram guided strategy for GP localization.
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- 2020
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50. The effect of idiopathic premature ventricular complexes on left ventricular ejection fraction.
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Altıntaş B, Özkalaycı F, Çinier G, Kaya İ, Aktan A, Küp A, Onuk R, Özcan S, Uslu A, Akyüz A, Atıcı A, Ekinci S, Akın H, Yılmaz MF, Koç Ş, Tanık VO, Harbalıoğlu H, Barman HA, Afşin A, Gümüşdağ A, Alibaşiç H, Karabağ Y, Cap M, Baysal E, and Tanboğa İH
- Subjects
- Adult, Cross-Sectional Studies, Echocardiography, Electrocardiography, Ambulatory, Female, Humans, Male, Middle Aged, Nomograms, Stroke Volume, Ventricular Dysfunction, Left physiopathology, Ventricular Premature Complexes physiopathology
- Abstract
Aim: Current literature lacks a definitive threshold of idiopathic premature ventricular complex (PVC) burden for predicting cardiomyopathy (CMP). The main objective of the present study was to evaluate relationship between the PVC burden and left ventricular ejection fraction (LVEF)., Method: This multicenter, cross-sectional study included 341 consecutive patients with more than 1,000 idiopathic PVC in 24 hr of Holter monitoring admitted to the cardiology clinics between January 2019 and May 2019 in the nineteen different centers. The primary outcome was the LVEF measured during the echocardiographic examination., Result: Overall, the median age was 50 (38-60) and 139 (49.4%) were female. Percentage of median PVC burden was 9% (IQR: 4%-17.4%). Median LVEF was found 60% (55-65). We used proportional odds logistic regression method to examine the relationship between continuous LVEF and candidate predictors. Increase in PVC burden (%) (regression coefficient (RE) -0.644 and 95% CI -1.063, -0.225, p < .001), PVC QRS duration (RE-0.191 and 95% CI -0.529, 0.148, p = .049), and age (RE-0.249 and 95% CI -0.442, -0.056, p = .018) were associated with decrease in LVEF. This inverse relationship between the PVC burden and LVEF become more prominent when PVC burden was above 5%. A nomogram developed to estimate the individual risk for decrease in LVEF., Conclusion: Our study showed that increase in PVC burden %, age, and PVC QRS duration were independently associated with decrease in LVEF in patients with idiopathic PVC. Also, inverse relationship between PVC burden and LVEF was observed in lower PVC burden than previously known., (© 2019 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals, Inc.)
- Published
- 2020
- Full Text
- View/download PDF
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