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202 results on '"VERMA, RENUKA"'

1. Factors associated with inpatient mortality during daunorubicin and cytarabine induction in adults with acute myeloid leukemia—a national inpatient sample analysis

Author

Savani, Saloni, Chennapragada, Suma Sri, Ramphul, Kamleshun, Dandwani, Mehndi, Verma, Renuka, Sanikommu, Sailaja, Pagidipally, Alekhya, Arti, FNU, Kumar, Vijay, Sombans, Shaheen, Ramphul, Yogeshwaree, Mejias, Stephanie G., Dhillon, Balkiranjit Kaur, Lohana, Petras, and Sharma, Shivani

Published
2024
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23. Diagnostic Utility of Bone Marrow Aspiration, Trephine Biopsy, and Flow Cytometry in the Evaluation of Various Haematological and Non Haematological Disorders: A Cross-sectional Study from Northern India.

Author

VERMA, RENUKA, KALRA, RAJNISH, GUPTA, VEENA, GUPTA, SUMITI, GUPTA, MONIKA, and SINGH, SUNITA

Subjects
*BONE marrow, *FLOW cytometry, *HODGKIN'S disease, *ACUTE leukemia, *MYELOFIBROSIS, BONE marrow examination
Abstract

Introduction: The spectrum of haematological and non haematological disorders is vast in various age groups. Complete blood counts and other routine laboratory tests are not always sufficient to diagnose these diseases. Bone marrow examination plays an important role in diagnosing their underlying causes. Aim: To analyse the spectrum of various haematological and non haematological disorders reported in Bone Marrow Aspiration (BMA) and compare them with Bone Marrow Trephine Biopsy (BMB) and Flow Cytometry (FCM) findings where applicable. Materials and Methods: A one-year cross-sectional study was conducted in the Department of Clinical Pathology, PGIMS, Rohtak, Haryana, India from April 2022 to March 2023. A total of 518 consecutive BMA samples were morphologically analysed. Comparative evaluations were performed among BMA, BMB, and FCM where applicable. Diagnostic accuracy was calculated, and the findings of discordant cases were tabulated. Definitive diagnosis of lymphoma/leukaemia and Paroxysmal Nocturnal Haemoglobinuria (PNH) cases were made using FCM. Results: The patients' ages ranged from three months to 86 years, with a mean age of 38.4 years. The male to female ratio was 1.3:1, with a slight male predominance. The highest number of cases were of anaemia {183 (35.3%) and 164 (31.7%), respectively} and leukaemia {128 (24.7%) and 134 (25.9%), respectively}, followed by normal marrow studies {39 (7.5%) and 32 (6.2%), respectively} and megakaryocytic thrombocytopenia {24 (4.6% in each} in both BMA and biopsy. Among anaemia cases {183 and 164 cases in BMA and BMB}, the majority were of the megaloblastic type {62 (33.8%) and 54 (32.9%), respectively}, followed by hypoplastic/aplastic type {40 (21.8%) and 50 (30.5%), respectively}. In cases of leukaemia (128 and 134 cases in BMA and BMB), acute leukaemia cases (76 (59.4%) and 82 (61.2%), respectively} outnumbered chronic leukaemia cases {52 (40.6%) and 52 (38.8%), respectively} in both BMA and BMB. The concordance and discordance rate between BMA and BMB were 87.6% (419 cases) and 12.4% (59 cases), respectively. Diagnosis was exclusively made by BMB in cases of myelofibrosis, granulomatous disease, and Hodgkin's lymphoma. Conclusion: BMA cytology is a relatively safe and mildly invasive technique for evaluating various haematological and non haematological disorders with better preservation of cellular morphology. However, in cases with dry/blood taps and focal marrow involvement, BMB should be performed, as it shows well-preserved marrow architecture with all its cellular and stromal components. FCM is a definitive diagnostic modality for further categorisation of acute leukaemia and Chronic Lymphoproliferative Disorders (CLPD). [ABSTRACT FROM AUTHOR]

Published
2024
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24. Disparities and Outcomes in the First and Second Year of the Pandemic on Events of Acute Myocardial Infarction in Coronavirus Disease 2019 Patients.

Author

Dhaliwal, Jasninder Singh, Sekhon, Manraj S., Rajotia, Arush, Dang, Ashujot K., Singh, Prabh Partap, Bilal, Maham, Sakthivel, Hemamalini, Ahmed, Raheel, Verma, Renuka, Ramphul, Kamleshun, and Sethi, Prabhdeep S.

Subjects
COVID-19, COVID-19 pandemic, ISCHEMIC stroke, MYOCARDIAL infarction, CORONAVIRUS diseases, ACUTE kidney failure, CARDIOLOGICAL manifestations of general diseases
Abstract

Background and Objectives: Coronavirus disease 2019 (COVID-19) caused several cardiovascular complications, including acute myocardial infarction (AMI), in infected patients. This study aims to understand the overall trends of AMI among COVID-19 patients during the first two years of the pandemic and the disparities and outcomes between the first and second years. Materials and Methods: The retrospective analysis was conducted via the 2020 and 2021 National Inpatient Sample (NIS) database for hospitalizations between April 2020 and December 2021 being analyzed for adults with a primary diagnosis of COVID-19 who experienced events of AMI. A comparison of month-to-month events of AMI and mortality of AMI patients with concomitant COVID-19 was made alongside their respective patient characteristics. Results: Out of 2,541,992 COVID-19 hospitalized patients, 3.55% experienced AMI. The highest rate of AMI was in December 2021 (4.35%). No statistical differences in trends of AMI mortality were noted over the 21 months. AMI cases in 2021 had higher odds of undergoing PCI (aOR 1.627, p < 0.01). They experienced higher risks of acute kidney injury (aOR 1.078, p < 0.01), acute ischemic stroke (aOR 1.215, p < 0.01), cardiac arrest (aOR 1.106, p < 0.01), need for mechanical ventilation (aOR 1.133, p < 0.01), and all-cause mortality (aOR 1.032, 95% CI 1.001–1.064, p = 0.043). Conclusions: The incidence of AMI among COVID-19 patients fluctuated over the 21 months of this study, with a peak in December 2021. COVID-19 patients reporting AMI in 2021 experienced higher overall odds of multiple complications, which could relate to the exhaustive burden of the pandemic in 2021 on healthcare, the changing impact of the virus variants, and the hesitancy of infected patients to seek care. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Evaluating the Hospitalizations Among Patients With Colorectal Cancer in the United States Between 2001 And 2020.

Author

Verma, Renuka, Ramphul, Kamleshun, and Sakthivel, Hemamalini

Abstract

The article focuses on evaluating hospitalizations among patients with colorectal cancer in the U.S. between 2001 and 2020, particularly examining trends based on different colon cancer locations. It mentions Using ICD-9 and ICD-10 codes, the study found stable numbers for patients with cancer in the transverse and descending colon, a decrease in hospitalizations for ascending colon cancer until 2014 followed by a rise until 2019.

Published
2024
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34. Outcomes of acute myocardial infarction in patients with renal cell carcinoma: a propensity-matched analysis from the national inpatient sample.

Author

Chennapragada, Suma Sri, Ramphul, Kamleshun, Savani, Saloni, Dandwani, Mehndi, Arora, Gagandeep Singh, Dhaliwal, Jasninder Singh, Aggarwal, Shruti, Verma, Renuka, Sanikommu, Sailaja, Pagidipally, Alekhya, Arti, Fnu, Kumar, Vijay, Sombans, Shaheen, Ramphul, Yogeshwaree, Pekyi-Boateng, Prince Kwabla, Elmahal, Mohammed, Mejias, Stephanie G, Dhillon, Balkiranjit Kaur, Lohana, Petras, and Sharma, Shivani

Subjects
RENAL cell carcinoma, MYOCARDIAL infarction, TREATMENT effectiveness
Published
2023
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35. Acute myocardial infarction among teenagers in the United States between 2016 and 2020: a retrospective analysis from the National Inpatient Sample.

Author

Ramphul, Kamleshun, Aggarwal, Shruti, Verma, Renuka, Lohana, Petras, Sombans, Shaheen, Ramphul, Yogeshwaree, Mejias, Stephanie Gonzalez, Kumar, Deepak, Kwansa, Nana Amma, and Pekyi-Boateng, Prince Kwabla

Subjects
MYOCARDIAL infarction, EXTRACORPOREAL membrane oxygenation, CARDIOGENIC shock, PERCUTANEOUS coronary intervention, MEDICAID beneficiaries
Abstract

Introduction: There is a lack of data on the characteristics of teenagers admitted with acute myocardial infarction (AMI). Recent studies have hinted that with changes in lifestyle and easier access to substances of abuse, people may be prone to several cardiovascular complications at an earlier age. Material and methods: Our analysis was based on the 2016-2020 National Inpatient Samples. Logistic models allowed us to investigate the adjusted odds ratios (aOR) of AMI among teenagers. We explored outcomes and complications such as cardiogenic shock, extracorporeal membrane oxygenation (ECMO), coronary artery bypass graft surgery (CABG), percutaneous coronary intervention (PCI), and mortality in these patients. Results: A total of 2170 cases of AMI were recorded between 2016 and 2020 (53.3 cases per 100,000 admissions among teenagers). Weekend admissions (26.3% vs. 20.9%, aOR = 1.298, p < 0.001), smokers (15.9% vs. 10.1%, aOR = 1.198, p = 0.007), cannabis users (18.9% vs. 8.4%, aOR = 1.558, p < 0.001), or cocaine users (5.3% vs. 0.6%, aOR = 4.84, p < 0.001) showed increased odds of recording a diagnosis of AMI. Females showed lower odds than males (32.7% vs. 65%, aOR = 0.264, 95% CI: 0.24-0.291, p < 0.001). Admissions were more likely among teenagers with hypertension (9.9% vs. 2.5%, aOR = 3.382, p < 0.001). Those not covered by Medicaid or private insurances were more likely to be admitted for AMI than Medicaid beneficiaries (12.4% vs. 8.2%, aOR = 1.278, p < 0.001). Finally, teenagers classified as Blacks showed higher odds than whites of being admitted for AMI (aOR = 1.37, p < 0.001). A total of 270 (12.5%) deaths were also noted. Conclusions: Various characteristics among teenagers influence their risk for AMI. Further studies and campaigns on educating teenagers about risk factors may provide long-term benefits. [ABSTRACT FROM AUTHOR]

Published
2023
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36. Racial Disparities in Mortality Among Non-Hispanic Whites, Asian-American/Pacific Islanders, and Hispanics After Percutaneous Coronary Intervention in the Prepandemic and Peak-Pandemic Era in the United States

Author

Dhillon, Sukhmeet, Verma, Renuka, Dhaliwal, Jasninder Singh, Passi, Jatin Kumar, Aggarwal, Shruti, Sombans, Shaheen, Ajitha, Salini, Aisha, FNU, Chennapragada, Suma Sri, Memon, Rahat Ahmed, Sakthivel, Hemamalini, and Ramphul, Kamleshun

Published
2023
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37. Investigating the impact of search results for fever, headache, cough, diarrhea, and nausea on the incidence of COVID-19 in India using Google Trends

Author

Verma, Renuka, Ramphul, Kamleshun, Kumar, Nomesh, and Lohana, Petras

Subjects
Search Engine, Betacoronavirus, Italy, Predictive Value of Tests, SARS-CoV-2, Correspondence, Pneumonia, Viral, COVID-19, Humans, Coronavirus Infections, Pandemics, Disease Outbreaks
Abstract

Digital epidemiology is increasingly used for supporting traditional epidemiology. This study was hence aimed to explore whether the Google search volume may have been useful to predict the trajectory of coronavirus disease 2019 (COVID-19) outbreak in Italy.We accessed Google Trends for collecting data on weekly Google searches for the keywords "tosse" (i.e., cough), "febbre" (i.e., fever) and "dispnea" (dyspnea) in Italy, between February and May 2020. The number of new weekly cases of COVID-19 in Italy was also obtained from the website of the National Institute of Health.The peaks of Google searches for the three terms predicted by 3 weeks that of newly diagnosed COVID-19 cases. The peaks of weekly Google searches for "febbre" (fever), "tosse"( cough) and "dispnea" (dyspnea) were 1.7-, 2.2- and 7.7-fold higher compared to the week before the diagnosis of the first national case. No significant correlation was found between the number of newly diagnosed COVID-19 cases and Google search volumes of "tosse" (cough) and "febbre" (fever), whilst "dyspnea" (dyspnea) was significantly correlated (r= 0.50; p=0.034). The correlation between newly diagnosed COVID-19 cases and "tosse" (cough; r=0.65; p=0.008) or "febbre" (fever; 0.69; p=0.004) become statistically significant with a 3-week delay. All symptoms were also significantly inter-correlated. Conclusions; Continuously monitoring the volume of Google searches and mapping their origin can be a potentially valuable instrument to help predicting and identifying local recrudescence of COVID-19.

Published
2021

38. SEVERITY OF OUTCOMES AMONG CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS WITH HOME OXYGEN USE FOLLOWING ADMISSION FOR NON-ST-ELEVATION MYOCARDIAL INFARCTION

Author

RAVALANI, ABHIMANYU, RAMPHUL, KAMLESHUN, MAL, MADHO, AGGARWAL, SHRUTI, KUMAR, GULSHAN, PREET, SARAN, SANIKOMMU, SAILAJA, KAUR DHILLON, BALKIRANJIT, KWABLA PEKYI-BOATENG, PRINCE, MEENA, INDU, GONZALEZ MEJIAS, STEPHANIE, RAMPHUL, YOGESHWAREEE, SOMBANS, SHAHEEN, VERMA, RENUKA, and SAKTHIVEL, HEMAMALINI

Published
2023
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47. DISPARITIES IN CARE AMONG LUNG CANCER PATIENTS UNDERGOING ROBOTIC-ASSISTED THORACOSCOPIC SURGERY IN URBAN TEACHING AND RURAL CENTERS IN THE UNITED STATES

Author

SAVANI, SALONI, RAMPHUL, KAMLESHUN, SRI CHENNAPRAGADA, SUMA, SHARMA, SHIVANI, DANDWANI, MEHNDI, RAVALANI, ABHIMANYU, VERMA, RENUKA, KWABLA PEKYI-BOATENG, PRINCE, SANIKOMMU, SAILAJA, AGGARWAL, SHRUTI, KUMAR, GULSHAN, PREET, SARAN, MAL, MADHO, SOMBANS, SHAHEEN, KAUR DHILLON, BALKIRANJIT, RAMPHUL, YOGESHWAREEE, PAGIDIPALLY, ALEKHYA, and SAKTHIVEL, HEMAMALINI

Published
2023
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