21 results on '"Kardes, Esra"'
Search Results
2. Efficacy of Simultaneous Application of Subretinal Tissue Plasminogen Activator and Bevacizumab for Submacular Hemorrhages.
- Author
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Limon, Utku, Gezginaslan, Tugba Aydogan, Saygin, Isilay Ozsoy, Bozkurt, Erdinc, Kardes, Esra, and Akcay, Betul Ilkay Sezgin
- Subjects
BEVACIZUMAB ,TISSUE plasminogen activator ,HEMORRHAGE treatment ,VITRECTOMY ,CARDIAC tamponade - Abstract
Objectives: The aim of the study was to evaluate the patients who received simultaneous subretinal tissue plasminogen activator (tPA) and bevacizumab for submacular hemorrhages secondary to neovascular age-related macular degeneration. Methods: This retrospective study included patients who underwent pars plana vitrectomy (PPV) with simultaneous subretinal tPA and subretinal bevacizumab with 18% SF6 tamponade. Anatomical and functional results of the patients before surgery and at the 1
st , 6th , and 12th months after surgery, additional treatments, and complications after PPV were evaluated. Results: Eight eyes of eight patients were included in the study. The mean age of the patients was 72.38±92.3. The mean time from the onset of symptoms to treatment was 5.13±1.88 days. The patients' mean best-corrected visual acuity (BCVA) was 2.23±0.14 logMAR at baseline. Mean BCVA increased significantly at 1st , 6th , and 12th months to 1.68±0.47 logMAR, 1.58±0.49 logMAR, and 1.51±0.58 logMAR, respectively (p=0.001 at all). The mean central foveal thickness (CFT) in measurable patients was 836.8±627.02 µm at baseline. Mean CFT decreased significantly to 370.13±66.13 µm in the 1st month, 373.38±78.33 µm in the 6th month, and 367.75±116.43 µm in the 12th month (p<0.05). The maximum measurable subretinal hemorrhage height at baseline was 814.2±556.45 µm. The mean number of anti-VEGFs performed for 12 months after surgery was 4.13±2.1. At month 12, the ellipsoid zone could not be detected in 6 (75%) patients. Conclusion: Administration of subretinal bevacizumab and subretinal tPA effectively removes subretinal hemorrhage under the fovea. Intravitreal anti-VEGF treatment must be continued, as choroidal neovascular membrane activity continues after surgery. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
- View/download PDF
3. Subfoveal choroidal thickness changes after intravitreal bevacizumab injection for neovascular age-related macular degeneration and diabetic macular edema
- Author
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Ünlü, Cihan, Erdogan, Gurkan, Gunay, Betul Onal, Kardes, Esra, Akcay, Betul Ilkay Sezgin, and Ergin, Ahmet
- Published
- 2017
- Full Text
- View/download PDF
4. Comparison of Clinical and Topographic Outcomes of Hybrid and Scleral Lenses in Advanced Keratoconus.
- Author
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Akcay, Betul Ilkay Sezgin, Kockar, Alev, Limon, Utku, Kardes, Esra, and Dursun, Aslihan Dogan
- Subjects
CONTACT lenses ,KERATOCONUS ,ASTIGMATISM ,VISUAL acuity ,STANDARD deviations - Abstract
Objectives: To evaluate and compare the effects of hybrid contact lenses (HCLs) and mini-scleral contact lenses (MSCLs) on visual acuity, spherical equivalent, topographic astigmatism, and higher-order aberrations (HOAs) in eyes with advanced keratoconus. Methods: We reviewed the medical records of 43 eyes of 27 patients diagnosed with advanced keratoconus fit hybrid contact lenses (AirFlex®) and mini-scleral contact lenses (Mini-misa®). Pre-fitting examinations included best corrected visual acuity (BCVA), spherical equivalent, topographic findings (topographic astigmatism, maximum keratometry, mean keratometry, central corneal thickness, thinnest corneal thickness, and corneal HOAs. Post-fitting examinations included lens corrected visual acuity, spherical equivalent, topographic astigmatism, corneal HOAs, and contact lens-related discomfort symptoms. Results: Mean BCVA (log MAR) improved significantly from 0.65±0.27 to 0.14±0.09 with HCL and 0.58±0.25 to 0.15±0.13 with MSCL (p<0.05). The mean spherical equivalent and topographic astigmatism measurements decreased significantly in both groups (p<0.05). Eight patients in the HCL group experienced lens-related discomfort. Root-mean square HOA decreased significantly in both groups (p<0.05). Conclusion: Significant improvements in visual acuity, spherical equivalent, topographic astigmatism, and HOAs were observed with both lenses. However, higher patient comfort with scleral lenses may lead to higher compliance in patients with advanced keratoconus. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
5. An Algorithm for the Diagnosis of Behçet Disease Uveitis in Adults.
- Author
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Tugal-Tutkun, Ilknur, Onal, Sumru, Stanford, Miles, Akman, Mehmet, Twisk, Jos W.R., Boers, Maarten, Oray, Merih, Özdal, P., Kadayifcilar, Sibel, Amer, Radgonde, Rathinam, Sivakumar R., Vedhanayaki, Rajesh, Khairallah, Moncef, Akova, Yonca, Yalcindag, F., Kardes, Esra, Basarir, Berna, Altan, Çigdem, Özyazgan, Yilmaz, and Gül, Ahmet
- Subjects
IRIDOCYCLITIS ,BEHCET'S disease ,CART algorithms ,UVEITIS ,DIAGNOSIS ,ADULTS - Abstract
Purpose: To develop an algorithm for the diagnosis of Behçet's disease (BD) uveitis based on ocular findings. Methods: Following an initial survey among uveitis experts, we collected multi-center retrospective data on 211 patients with BD uveitis and 207 patients with other uveitides, and identified ocular findings with a high diagnostic odds ratio (DOR). Subsequently, we collected multi-center prospective data on 127 patients with BD uveitis and 322 controls and developed a diagnostic algorithm using Classification and Regression Tree (CART) analysis and expert opinion. Results: We identified 10 items with DOR >5. The items that provided the highest accuracy in CART analysis included superficial retinal infiltrate, signs of occlusive retinal vasculitis, and diffuse retinal capillary leakage as well as the absence of granulomatous anterior uveitis or choroiditis in patients with vitritis. Conclusion: This study provides a diagnostic tree for BD uveitis that needs to be validated in future studies. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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- View/download PDF
6. Axenfeld-Rieger syndrome in monozygotic twin brothers: Case report.
- Author
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Sezgi̇n Akcay, Betul Ilkay, Kardes, Esra, and Li̇mon, Utku
- Subjects
AXENFELD-Rieger syndrome ,GENETIC disorders ,GLAUCOMA ,OPHTHALMOLOGY ,HYPOSPADIAS - Abstract
Axenfeld-Rieger syndrome (ARS) is a genetic disease affecting multiple organ systems. In the eye, it is associated with anterior segment dysgenesis with a high risk for glaucoma. Dental anomalies, cardiovascular malformations, hypospadias, and craniofacial abnormalities are other associated systemic conditions. Five years old monozygotic twin brothers with ARS were referred to Umraniye Training and Research Hospital, ophthalmology clinic for iris abnormalities. At presentation, pathognomonic components of ARS were found in both patients, including iris anomaly (corectopia, iris hypoplasia, and iris strands in Scwalbe’s ring), oligodontia, hypodontia, hypospadias, and periumbilical skin fold. Intraocular pressure was within normal ranges in both of the patients. Patients were followed up in the glaucoma unit. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
7. Implantation of foldable posterior chamber intraocular lens in aphakic vitrectomized eyes without capsular support
- Author
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Erdogan, Gurkan, Unlu, Cihan, Gunay, Betul Onal, Kardes, Esra, and Ergin, Ahmet
- Subjects
genetic structures ,Iris/surgery ,Suture techniques ,Afacia ,Técnicas de sutura ,Lens implantation, intraocular/methods ,Implante de lente intraocular/métodos ,Íris/cirurgia ,Aphakia - Abstract
Purpose: To evaluate the outcomes of three different surgical techniques for foldable posterior chamber intraocular lens (PCIOL) implantation in vitrectomized eyes without capsular support. Methods: A total of 60 patients with aphakic and vitrectomized eyes without capsular support were enrolled. All patients underwent three-piece foldable PCIOL implantation into the posterior chamber through a small corneal incision. Transscleral fixation (TSF), iris fixation (IF), and intrascleral tunnel fixation (ISF) surgical techniques were performed. Results: Postoperative PCIOL subluxation or dislocation occurred in one case in the TSF group and two cases in the ISF group. Intraoperative PCIOL dislocation occurred in two patients in the IF group. The incidence of temporary postoperative complications, such as mild intraocular hemorrhage and cystoid macular edema, was higher in the ISF group. No statistically significant difference in PCIOL-related astigmatism was observed between groups. Visual acuity improved in all groups. Conclusions: Postoperative outcomes were comparable between TSF, IF, and ISF for PCIOL in vitrectomized eyes without capsular support. RESUMO Objetivo: Avaliar os resultados de três diferentes técnicas cirúrgicas para implantação da lente intraocular de câmara posterior (PCIOL) dobrável em olhos vitrectomizados sem apoio capsular. Métodos: Um total de 60 olhos de 60 pacientes afácicos vitrectomizados, sem apoio capsular foram inscritos. Todos os pacientes foram submetidos ao implante de PCIOL dobrável de três peças na câmara posterior, através de uma pequena incisão na córnea. Foram utilizados as técnicas cirúrgicas de fixação transescleral (TSF), fixação iriana (IF) e túnel de fixação intraescleral (ISF). Resultados: Subluxação ou luxação da PCIOL ocorreu em um caso no grupo TSF e em dois casos no grupo ISF. Deslocamentos intraoperatórios da PCIOL ocorram em dois pacientes no grupo IF. Frequência de complicações pós-operatórias temporárias como hemorragia intraocular leve e edema macular cistóide foi maior no grupo ISF. Não houve diferença estatisticamente significativa do astigmatismo relacionado à PCIOL entre os grupos. A acuidade visual melhorou em todos os grupos. Conclusões: Nenhuma das três técnicas cirúrgicas teve destaque em termos de resultados cirúrgicos comparativos.
- Published
- 2016
8. Purtscher-Like Retinopathy Associated with Anorexia Nervosa
- Author
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Karasu, Bugra, Gunay, Betul Onal, Erdogan, Gurkan, Kardes, Esra, and Gunay, Murat
- Subjects
genetic structures ,Article Subject ,sense organs ,eye diseases - Abstract
A 21-year-old girl presented with acute painless vision loss in her right eye. There was no remarkable ocular history and she had a history of anorexia nervosa. At presentation best-corrected visual acuities were counting fingers from 2 meters and 20/20, in the right and left eyes, respectively. Slit lamp examination result was normal. Fundus examination revealed multiple cotton wool spots and intraretinal hemorrhages surrounding the optic disc and macula in the right eye. Fluorescein angiography showed capillary filling defect and leakage from optic disc in the late phase of the angiogram. One week later best-corrected visual acuities remained the same in both eyes with similar fundus appearance. One month after initial presentation visual acuity was 20/20 in both eyes with no abnormality in fundus appearance.
- Published
- 2016
- Full Text
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9. Evaluation of the Ganglion Cell Complex and Retinal Nerve Fiber Layer in Low, Moderate, and High Myopia: A Study by RTVue Spectral Domain Optical Coherence Tomography.
- Author
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Sezgin Akcay, Betul Ilkay, Gunay, Betul Onal, Kardes, Esra, Unlu, Cihan, and Ergin, Ahmet
- Subjects
RETINAL ganglion cells ,GANGLIONIC stimulating agents ,MYOPIA treatment ,RETINAL degeneration treatment ,OPTICAL coherence tomography ,NEURAL physiology ,MYOPIA ,PHARMACOKINETICS ,RETINA - Abstract
Purpose: To assess the effect of low, moderate, and high myopia on the thickness of the retinal nerve fiber layer (RNFL) and Ganglion cell complex (GCC) measured by Spectral Domain Optical Coherence Tomography (SD-OCT) in non-glaucomatous subjects.Methods: The subjects were divided into three groups: low (n = 81, 35.6%), moderate (n = 79, 34.8%), and highly myopic eyes (n = 67, 29.5%). The RNFL thickness profile, including the average, superior, nasal, inferior, and temporal quadrant and each of the eight directional thicknesses, was measured. GCC parameters, including the average, superior, and inferior values, the focal loss volume (FLV), and the global loss volume (GLV), were measured. The correlation between the OCT measurements and the axial length was evaluated.Results: The average, superior, inferior, and nasal RNFL thicknesses of low and moderate myopic eyes were found to be significantly higher than those of highly myopic eyes. The temporal RNFL thicknesses were not different among the three groups. The average, superior, and inferior ganglion cell complex values of low and moderate myopic eyes were significantly higher than those of highly myopic eyes. The FLV and GLV of low and moderate myopic eyes were significantly higher than those of highly myopic eyes (p = 0.001 for all). In the moderate and high myopia groups, the average RNFL thickness and GCC thickness were both negatively correlated with the axial length.Conclusion: Highly myopic subjects tend to have thinner RNFL and GCC thicknesses than subjects with low and moderate myopia. [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
- View/download PDF
10. Choroidal Thickness in Eyes with Fuchs Uveitis Syndrome.
- Author
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Kardes, Esra, Sezgin Akçay, Betül Ilkay, Unlu, Cihan, and Ergin, Ahmet
- Subjects
- *
UVEITIS , *CHOROID , *RETINAL ganglion cells , *THICKNESS measurement , *OPTICAL coherence tomography , *PATIENTS , *CORNEA diseases , *IRIDOCYCLITIS , *UVEAL diseases , *ANTHROPOMETRY , *NEURONS , *RETINA , *UVEA , *VISUAL acuity , *DIAGNOSIS - Abstract
Purpose: This study measured the macular thickness, peripapillary retinal nerve fiber layer (RNFL) thickness, subfoveal choroidal thickness (SFCT), and ganglion cell complex (GCC) thickness in eyes with Fuchs uveitis syndrome (FUS).Methods: In total, 25 patients with unilateral FUS were enrolled. The diagnosis of FUS was based on the presence of several of the following clinical features: absence of acute symptoms and ciliary injection; small to medium-sized and stellate keratic precipitates (KP) diffusely scattered on the entire corneal endothelium; chronic low-grade anterior chamber inflammation; iris stromal atrophy with or without heterochromia; lack of posterior synechiae; iris nodules; and vitreous cells and debris. Spectral domain optical coherence tomography (SD-OCT; RTVue-100 OCT) was used to obtain the measurements. The SFCT, RNFL thickness, macular retinal thickness, and GCC thickness of the eyes with FUS were measured and compared with those of the uninvolved fellow eyes. A paired samples t-test was used for statistical analyses. A value of p<0.05 was considered to be statistically significant for all analyses.Results: The mean age of the patients was 35.2 ± 4.8 years. Fifteen patients (60%) were male, and 10 (40%) were female. Small- to medium-sized stellate KPs and mild anterior chamber reactions were seen in all patients. Heterochromia was observed in 24% of the eyes, iris nodules in 36% of the eyes, lens opacity in 44% of the eyes, and vitreous cells and debris in 88% of the eyes. The mean SFCT was significantly thinner in eyes with FUS (296.47 ± 32.29 µm) than in the fellow eyes without FUS (324.47 ± 26.73 µm; p = 0.001). The mean average GCC thickness was found to be 101.09 ± 5.46 µm in eyes with FUS and 103.80 ± 6.65 µm in eyes without FUS (p = 0.023). There were no significant differences in the mean RNFL and macular thickness values.Conclusions: We detected subfoveal choroidal thinning in eyes with FUS when compared with the uninvolved fellow eyes. In our opinion, thinning of the SFCT in FUS might be associated with autoimmune responses and chronic inflammatory processes. [ABSTRACT FROM AUTHOR]- Published
- 2017
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11. Subfoveal choroidal thickness changes after intravitreal bevacizumab therapy for central serous chorioretinopathy.
- Author
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ÜNLü, CIHAN, ERDOGAN1, GURKAN, GEZGINASLAN, TUGBA AYDOGAN, AKCAY, BETUL ILKAY SEZGIN, KARDES, ESRA, and BOZKURT, TAHIR KANSU
- Subjects
BEVACIZUMAB ,RETINAL detachment ,CHOROID diseases ,OPTICAL coherence tomography ,ACETAZOLAMIDE ,NONSTEROIDAL anti-inflammatory agents ,LASER photocoagulation ,THERAPEUTICS - Abstract
Copyright of Arquivos Brasileiros de Oftalmologia is the property of Arquivos Brasileiros de Oftalmologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
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12. COMPARING PERIPHERAL VITRECTOMY UNDER AIR AND FLUID INFUSION FOR PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT.
- Author
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ERDOGAN, GURKAN, UNLU, CIHAN, KARASU, BUGRA, KARDES, ESRA, and ERGIN, AHMET
- Published
- 2016
13. Intravitreal Bevacizumab for Treatment of Central Serous Chorioretinopathy.
- Author
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Ürlü, Cihan, Erdogan, Gurkan, Aydogan, Tugba, Sezgin Akcay, Betul Ilkay, Kardes, Esra, Kiray, Gulunay Akcali, and Bozkurt, Tahir Kansu
- Published
- 2016
- Full Text
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14. Correlation Between Retinal Nerve Fiber Layer, Optic Nerve Head and Macular Parameters and Structure Function Relationship in Glaucoma.
- Author
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AYDOGAN GEZGINASLAN, Tugba, SEZGIN AKCAY, Betul Ilkay, and KARDES, Esra
- Subjects
- *
OPTIC nerve , *GLAUCOMA , *OPTICAL coherence tomography , *OCULAR hypertension , *VISUAL fields , *OPTIC disc , *NERVE fibers - Abstract
Purpose: To evaluate correlation between visual field indices and spectral domain optical coherence tomography (SD-OCT) parameters and correlation among SD-OCT parameters to have a better understanding of role of SD-OCT parameters in clinical practice. Materials and Methods: This is a retrospective controlled clinical study. Three hundred forty-three eyes (91 healthy, 80 ocular hypertension, 97 preperimetric glaucoma and 75 early glaucoma eyes) were analyzed. Retinal nerve fiber layer (RNFL), macular, optic nerve head (ONH) parameters were measured with SD-OCT. Correlation between visual field indices and SD-OCT parameters and correlation among SD-OCT parameters were calculated. Results: Average RNFL showed the best correlation with both mean deviation (MD) (r = 0.624) and pattern standard deviation (PSD) (r = 0.614). Other RNFL parameters, ganglion cell complex (GCC) parameters and total retina (TR) parameters showed moderate correlation whereas outer retina (OR) and ONH parameters showed poor correlation with MD. Correlation between RNFL and GCC parameters was strong. Correlation between RNFL and TR parameters was moderate. Poor correlation were found between OR parameters and both RNFL and GCC parameters. Moderate correlation was found between average RNFL and both rim area and rim volume. Other correlations with ONH parameters were poor. Conclusion: Good structure function relationship is present between visual field indices and SD-OCT parameters like RNFL and GCC parameters. These parameters reflect the severity of glaucoma and can be used for glaucoma monitoring. TR and some ONH parameters like rim area and volume can give supplementary information to use in clinical practice. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
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15. Axenfeld-Rieger syndrome in monozygotic twin brothers: Case report.
- Author
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Akcay BIS, Kardes E, and Limon U
- Abstract
Axenfeld-Rieger syndrome (ARS) is a genetic disease affecting multiple organ systems. In the eye, it is associated with anterior segment dysgenesis with a high risk for glaucoma. Dental anomalies, cardiovascular malformations, hypospadias, and craniofacial abnormalities are other associated systemic conditions. Five years old monozygotic twin brothers with ARS were referred to Umraniye Training and Research Hospital, ophthalmology clinic for iris abnormalities. At presentation, pathognomonic components of ARS were found in both patients, including iris anomaly (corectopia, iris hypoplasia, and iris strands in Scwalbe's ring), oligodontia, hypodontia, hypospadias, and periumbilical skin fold. Intraocular pressure was within normal ranges in both of the patients. Patients were followed up in the glaucoma unit., Competing Interests: No conflict of interest was declared by the authors., (© Copyright 2022 by Istanbul Provincial Directorate of Health.)
- Published
- 2022
- Full Text
- View/download PDF
16. Comparison of Clinical and Topographic Outcomes of Hybrid and Scleral Lenses in Advanced Keratoconus.
- Author
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Akcay BIS, Kockar A, Limon U, Kardes E, and Dursun AD
- Abstract
Objectives: To evaluate and compare the effects of hybrid contact lenses (HCLs) and mini-scleral contact lenses (MSCLs) on visual acuity, spherical equivalent, topographic astigmatism, and higher-order aberrations (HOAs) in eyes with advanced keratoconus., Methods: We reviewed the medical records of 43 eyes of 27 patients diagnosed with advanced keratoconus fit hybrid contact lenses (AirFlex®) and mini-scleral contact lenses (Mini-misa®). Pre-fitting examinations included best corrected visual acuity (BCVA), spherical equivalent, topographic findings (topographic astigmatism, maximum keratometry, mean keratometry, central corneal thickness, thinnest corneal thickness, and corneal HOAs. Post-fitting examinations included lens corrected visual acuity, spherical equivalent, topographic astigmatism, corneal HOAs, and contact lens-related discomfort symptoms., Results: Mean BCVA (log MAR) improved significantly from 0.65±0.27 to 0.14±0.09 with HCL and 0.58±0.25 to 0.15±0.13 with MSCL (p<0.05). The mean spherical equivalent and topographic astigmatism measurements decreased significantly in both groups (p<0.05). Eight patients in the HCL group experienced lens-related discomfort. Root-mean square HOA decreased significantly in both groups (p<0.05)., Conclusion: Significant improvements in visual acuity, spherical equivalent, topographic astigmatism, and HOAs were observed with both lenses. However, higher patient comfort with scleral lenses may lead to higher compliance in patients with advanced keratoconus., Competing Interests: Conflict of Interest: None declared., (Copyright: © 2022 by Beyoglu Eye Training and Research Hospital.)
- Published
- 2021
- Full Text
- View/download PDF
17. COMPARING PERIPHERAL VITRECTOMY UNDER AIR AND FLUID INFUSION FOR PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT.
- Author
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Erdogan G, Unlu C, Karasu B, Kardes E, and Ergin A
- Subjects
- Adult, Aged, Aged, 80 and over, Case-Control Studies, Drug Combinations, Female, Humans, Intraoperative Complications, Male, Middle Aged, Postoperative Complications, Retrospective Studies, Visual Acuity physiology, Acetates administration & dosage, Air, Minerals administration & dosage, Retinal Detachment surgery, Sodium Chloride administration & dosage, Vitrectomy
- Abstract
Purpose: To evaluate the efficacy and safety of peripheral vitrectomy under air infusion in comparison with fluid infusion in patients undergoing 23-gauge pars plana vitrectomy for primary rhegmatogenous retinal detachment., Methods: A total of 80 eyes of 80 patients with primary rhegmatogenous retinal detachment were enrolled into the study. Forty cases underwent peripheral vitrectomy under air infusion (air group), and a control group of equal number underwent peripheral vitrectomy under fluid infusion (fluid group). Peripheral iatrogenic retinal breaks during peripheral vitrectomy, postoperative visual acuities, and retinal redetachment rates were compared., Results: The number of eyes with peripheral iatrogenic retinal breaks in air group during peripheral vitrectomy was statistically comparable with that in fluid group (1/40 and 4/40, 2.5% and 10%, respectively; P = 0.16). Scleral depression was necessitated in 7 of 40 cases (17.5%) during the operation in the air group. There were no statistically significant differences between the groups in means of postoperative visual acuity and retinal redetachment (P = 0.18 and P = 1.0, respectively)., Conclusion: Peripheral vitrectomy under air infusion for primary rhegmatogenous retinal detachment revealed comparable results with fluid infusion in terms of intraoperative and postoperative complications and surgical outcomes.
- Published
- 2016
- Full Text
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18. Implantation of foldable posterior chamber intraocular lens in aphakic vitrectomized eyes without capsular support.
- Author
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Erdogan G, Unlu C, Gunay BO, Kardes E, and Ergin A
- Subjects
- Aged, Astigmatism etiology, Cornea surgery, Female, Humans, Iris surgery, Lens Implantation, Intraocular adverse effects, Male, Middle Aged, Postoperative Complications, Retrospective Studies, Sclera surgery, Statistics, Nonparametric, Suture Techniques, Time Factors, Treatment Outcome, Visual Acuity, Vitrectomy adverse effects, Aphakia surgery, Lens Implantation, Intraocular methods, Lenses, Intraocular, Vitrectomy methods
- Abstract
Purpose: To evaluate the outcomes of three different surgical techniques for foldable posterior chamber intraocular lens (PCIOL) implantation in vitrectomized eyes without capsular support., Methods: A total of 60 patients with aphakic and vitrectomized eyes without capsular support were enrolled. All patients underwent three-piece foldable PCIOL implantation into the posterior chamber through a small corneal incision. Transscleral fixation (TSF), iris fixation (IF), and intrascleral tunnel fixation (ISF) surgical techniques were performed., Results: Postoperative PCIOL subluxation or dislocation occurred in one case in the TSF group and two cases in the ISF group. Intraoperative PCIOL dislocation occurred in two patients in the IF group. The incidence of temporary postoperative complications, such as mild intraocular hemorrhage and cystoid macular edema, was higher in the ISF group. No statistically significant difference in PCIOL-related astigmatism was observed between groups. Visual acuity improved in all groups., Conclusions: Postoperative outcomes were comparable between TSF, IF, and ISF for PCIOL in vitrectomized eyes without capsular support.
- Published
- 2016
- Full Text
- View/download PDF
19. Intravitreal Bevacizumab for Treatment of Central Serous Chorioretinopathy.
- Author
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Ünlü C, Erdogan G, Aydogan T, Sezgin Akcay BI, Kardes E, Kiray GA, and Bozkurt TK
- Abstract
Purpose: To compare the outcomes of treatment with intravitreal bevacizumab (IVB) versus observation in central serous chorioretinopathy (CSCR)., Methods: In a retrospective comparative study, records of 45 patients with CSCR were reviewed. Twenty-two patients received IVB (1.25 mg/0.05 ml) while 23 subjects were observed. All subjects underwent measurement of best corrected visual acuity (BCVA) and intraocular pressure (IOP), dilated fundus examination and optical coherence tomography (OCT) imaging at baseline and follow up visits. Outcome measures included central macular thickness (CMT) and BCVA in logarithm of minimum angle of resolution (logMAR) notations., Results: Mean age was 44.1 ± 9.3 (range: 24 to 64) years and mean follow-up period was 10.4 ± 11.2 (range: 3 to 43; median: 6) months. All patients demonstrated resolution of neurosensory detachment and improvement in visual acuity. At final visit, there was no significant difference in mean CMT between the IVB and observation groups (275 vs 284 μm, P> 0.05). Mean baseline logMAR visual acuity was 0.38 ± 0.24 in the IVB group which improved to 0.24 ± 0.31 at final follow-up (P = 0.011); mean baseline logMAR visual acuity was 0.42 ± 0.28 in the observation group and improved to 0.12 ± 0.18 (P = 0.001). Visual improvement was more marked in the observation group (0.30 vs 0.14 logMAR, P< 0.05) and mean final visual acuity was also significantly better (P = 0.05)., Conclusion: There was no significant difference between IVB injection and observation in terms of anatomical outcomes of treatment for CSCR. In terms of visual outcomes, observation was superior to IVB injection.
- Published
- 2016
- Full Text
- View/download PDF
20. Subfoveal choroidal thickness changes after intravitreal bevacizumab therapy for neovascular age-related macular degeneration.
- Author
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Ünlü C, Erdogan G, Onal Gunay B, Sezgin Akcay BI, and Kardes E
- Published
- 2015
- Full Text
- View/download PDF
21. Clinical characteristics of intermediate uveitis in adult Turkish patients.
- Author
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Kardes E, Sezgin Akcay BI, Bozkurt K, Unlu C, Erdogan G, and Akcali G
- Abstract
Aim: To describe the clinical characteristics of Turkish patients with intermediate uveitis (IU) and to investigate the effect of clinical findings and complications on final visual acuity (VA)., Methods: We retrospectively analyzed the medical records of patients with IU who had at least 6mo of follow-up and were older than 16y., Results: A total of 78 eyes of 45 patients were included in the study and the mean follow-up period was 19.4mo. The mean age at the time of presentation was 42.9s. Systemic disease associations were found in 17.7% of cases; sarcoidosis (8.8%) and multiple sclerosis (6.6%) were the most common diseases. Recurrence rate (odds ratio=45.53; 95%CI: 2.181-950.58), vitritis equals to or more than 3+ cells (odds ratio=57.456; 95%CI: 4.154-794.79) and presenting with VA less than 20/40 (odds ratio=43.81; 95%CI: 2.184-878.71) were also found as high risk factors for poor final VA. At the last follow-up examination, 67.9% of eyes had VA of 20/40 or better., Conclusion: IU is frequently seen at the beginning of the fourth decade of life. The disease is most commonly idiopathic in adult Turkish patients. Patients with severe vitritis at presentation and patients with frequent recurrences are at high risk for poor visual outcome.
- Published
- 2015
- Full Text
- View/download PDF
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