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349 results on '"Khairallah, Moncef"'

1. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 2—global current practice patterns for the management of Cytomegalovirus anterior uveitis

Author

Thng, Zheng Xian, Putera, Ikhwanuliman, Testi, Ilaria, Chan, Kevin, Westcott, Mark, Chee, Soon-Phaik, Dick, Andrew D., Kempen, John H., Bodaghi, Bahram, Thorne, Jennifer E., Barisani-Asenbauer, Talin, de Smet, Marc D., Smith, Justine R., McCluskey, Peter, La Distia Nora, Rina, Jabs, Douglas A., de Boer, Joke H., Sen, H. Nida, Goldstein, Debra A., Khairallah, Moncef, Davis, Janet L., Rosenbaum, James T., Jones, Nicholas P., Nguyen, Quan Dong, Pavesio, Carlos, Agrawal, Rupesh, and Gupta, Vishali

Published
2024
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2. The Infectious Uveitis Treatment Algorithm Network (TITAN) Report 1—global current practice patterns for the management of Herpes Simplex Virus and Varicella Zoster Virus anterior uveitis

Author

Thng, Zheng Xian, Putera, Ikhwanuliman, Testi, Ilaria, Chan, Kevin, Westcott, Mark, Chee, Soon-Phaik, Dick, Andrew D., Kempen, John H., Bodaghi, Bahram, Thorne, Jennifer E., Barisani-Asenbauer, Talin, de Smet, Marc D., Smith, Justine R., McCluskey, Peter, La Distia Nora, Rina, Jabs, Douglas A., de Boer, Joke H., Sen, H. Nida, Goldstein, Debra A., Khairallah, Moncef, Davis, Janet L., Rosenbaum, James T., Jones, Nicholas P., Nguyen, Quan Dong, Pavesio, Carlos, Agrawal, Rupesh, and Gupta, Vishali

Published
2024
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3. The Humira in Ocular Inflammations Taper (HOT) Study

Author

Pichi, Francesco, Smith, Scott D., Goldstein, Debra A., Baddar, Dina, Gerges, Terese K.A., Janetos, Timothy M., Ruiz-Cruz, Matilde, Elena Concha-del-Río, Luz, Maruyama, Kazuichi, Carina ten Berge, Josianne, Rombach, Saskia M., Cimino, Luca, Bolletta, Elena, Miserocchi, Elisabetta, Scandale, Pierluigi, Serafino, Massimiliano, Camicione, Paola, Androudi, Sofia, Gonzalez-Lopez, Julio J., Lim, Lyndell L., Singh, Nandini, Gupta, Vishali, Gupta, Nikita, Amer, Radgonde, Dodds, Emilio M., Inchauspe, Sebastian, Munk, Marion R., Donicova, Emilia, Carreño, Ester, Takeuchi, Masaru, Chee, Soon-Phaik, Chew, Milton C., Agarwal, Aniruddha, Schlaen, Ariel, Gómez, Ramiro A., Couto, Cristobal A., Khairallah, Moncef, and Neri, Piergiorgio

Published
2024
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5. Effective refractive error coverage in adults aged 50 years and older: estimates from population-based surveys in 61 countries

Author

Bron, Alain, Cheng, Ching-Yu, Fernandes, Arthur, Friedman, David, Gazzard, Andrew, Kahloun, Rim, Kempen, John, Khairallah, Moncef, Lansingh, Van C, Leasher, Janet, Leveziel, Nicolas, Limburg, Hans, Nowak, Michal, Pesudovs, Konrad, Peto, Tunde, Rossetti, Luca, Tahhan, Nina, Varma, Rohit, Alemayehu, Wondu, Arditi, Aries, Dana, Reza, Del Monte, Monte, Deva, jenny, Dreer, Laura, Ehrlich, Josh, Ellwein, Leon, Hammond, Billy, Hartnett, Mary E, Ingram, April, Khanna, Rohit, Kim, Judy, Lim, Jennifer, Morse, Alan, Musch, David, Parodi, Maurizio B, Ramulu, Pradeep, Robin, Alan, Serle, Janet, Shen, Tueng, Sitorus, Rita S, Stambolian, Dwight, Topouzis, Fotis, Tsilimbaris, Miltiadis, Virgili, Gianni, West, Sheila, Ababora, Jafer K, AlSawahli, Heba, Andriamanjato, Hery Harimanitra, Barrenechea, Rosario, Batlle, Juan F, Burnett, Anthea M, Finger, Robert P, Gallarreta, Marcelo, Gomez-Bastar, Pedro A, Gurung, Reeta, Jain, Elesh, Kabona, George E, Kalua, Khumbo, Kandeke, Levi, Karimurio, Jefitha, Kikira, Susan A, Kulkarni, Sucheta, Mathenge, Wanjiku, Mishra, Sailesh Kumar, Mohammadi, Seyed Farzad, Mörchen, Manfred, Muhammad, Nasiru, Mutati, Grace C, Nano, Maria Eugenia, Németh, János, Paduca, Ala, Páez, Alexander, Rabiu, M Mansur, Rif'ati, Lutfah, Salowi, Mohamad Aziz, Sapkota, Yuddha D, Sargent, Nicholas, Thoufeeq, Ubeydulla, Villalobos, Astrid V, Xiao, Biaxiang, Yee Melgar, Mariano, Zhang, Xiu Juan, Bourne, Rupert Richard Alexander, Cicinelli, Maria Vittoria, Sedighi, Tabassom, Tapply, Ian H, McCormick, Ian, Jonas, Jost B, Congdon, Nathan G, Ramke, Jacqueline, Naidoo, Kovin S, Fricke, Timothy R, Burton, Matthew J, Müller, Andreas, Bikbov, Mukharram M, Furtado, João M, Kyari, Fatima, He, Mingguang, Wang, Ya Xing, Vijaya, Lingam, Nangia, Vinay, Brian, Garry, Emamian, Mohammad Hassan, Fotouhi, Akbar, Hashemi, Hassan, Khandekar, Rajiv B, Marmamula, Srinivas, Salomão, Solange, George, Ronnie, Kazakbaeva, Gyulli, Braithwaite, Tasanee, Casson, Robert J, Iwase, Aiko, Gupta, Noopur, Abdianwall, Mohammad H, Wong, Tien Y, Wang, Ningli, Taylor, Hugh R, Flaxman, Seth R, Keel, Stuart, and Resnikoff, Serge

Published
2022
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8. Lens-induced hypopyon uveitis as the presenting manifestation of posterior lens nucleus dislocation following pars-plana vitrectomy: case report

Author

Ksiaa Imen, Ben Hadj Tahar Meriam, Sellem Ilhem, Attia Sonia, Abroug Nesrine, and Khairallah Moncef

Subjects
Pars-plana vitrectomy, Gas tamponade, Dislocated lens, Lens-induced uveitis, Ophthalmology, RE1-994
Abstract

Abstract A 57-year-old otherwise healthy male presented to our department seven days following uneventful pars-plana vitrectomy with gas tamponade for a superior bullous retinal detachment in the left eye. Ophthalmic examination revealed anterior segment inflammation with hypopyon and fibrinous exudate. Intra-ocular pressure was 28 mmHg. Posterior segment evaluation was difficult to assess due to the presence of anterior capsule opacification and gas bubble. A Toxic Anterior Segment Syndrome was suspected, and the patient was treated with topical and oral corticosteroid medication in combination with anti-glaucomatous therapy. On follow-up, anterior segment inflammation and ocular hypertension improved. On day ten post-operatively, ocular ultrasonography demonstrated lens material inferiorly with attached retina. The final diagnosis of posterior lens nucleus dislocation with lens-induced uveitis was retained. The patient underwent an uneventful second vitrectomy with aspiration of the dislocated lens nucleus and sulcus three piece-lens implantation. On last follow-up, visual acuity was 20/50 with no relapsing of ocular inflammation and the retina remained reattached.

Published
2021
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9. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study

Author

Steinmetz, Jaimie D, Bourne, Rupert R A, Briant, Paul Svitil, Flaxman, Seth R, Taylor, Hugh R B, Jonas, Jost B, Abdoli, Amir Aberhe, Abrha, Woldu Aberhe, Abualhasan, Ahmed, Abu-Gharbieh, Eman Girum, Adal, Tadele Girum, Afshin, Ashkan, Ahmadieh, Hamid, Alemayehu, Wondu, Alemzadeh, Sayyed Amirpooya Samir, Alfaar, Ahmed Samir, Alipour, Vahid, Androudi, Sofia, Arabloo, Jalal, Arditi, Aries Berhe, Aregawi, Brhane Berhe, Arrigo, Alessandro, Ashbaugh, Charlie, Ashrafi, Elham Debalkie, Atnafu, Desta Debalkie, Bagli, Eleni Amin, Baig, Atif Amin Winfried, Bärnighausen, Till Winfried, Battaglia Parodi, Maurizio, Beheshti, Mahya Srikanth, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bijani, Ali, Bikbov, Mukharram, Bottone, Michele, Braithwaite, Tasanee M, Bron, Alain M, Burugina Nagaraja, Sharath A, Butt, Zahid A, Caetano dos Santos, Florentino Luciano L, Carneiro, Vera L James, Casson, Robert James, Cheng, Ching-Yu Jasmine, Choi, Jee-Young Jasmine, Chu, Dinh-Toi, Cicinelli, Maria Vittoria M, Coelho, João M G, Congdon, Nathan G A, Couto, Rosa A A, Cromwell, Elizabeth A M, Dahlawi, Saad M, Dai, Xiaochen, Dana, Reza, Dandona, Lalit, Dandona, Rakhi A, Del Monte, Monte A, Derbew Molla, Meseret, Dervenis, Nikolaos Alemayehu, Desta, Abebaw Alemayehu P, Deva, Jenny P, Diaz, Daniel, Djalalinia, Shirin E, Ehrlich, Joshua R, Elayedath, Rajesh Rashad, Elhabashy, Hala Rashad B, Ellwein, Leon B, Emamian, Mohammad Hassan, Eskandarieh, Sharareh, Farzadfar, Farshad G, Fernandes, Arthur G, Fischer, Florian S, Friedman, David S M, Furtado, João M, Gaidhane, Shilpa, Gazzard, Gus, Gebremichael, Berhe, George, Ronnie, Ghashghaee, Ahmad, Gilani, Syed Amir, Golechha, Mahaveer, Hamidi, Samer Randall, Hammond, Billy Randall R, Hartnett, Mary Elizabeth R Kusuma, Hartono, Risky Kusuma, Hashi, Abdiwahab I, Hay, Simon I, Hayat, Khezar, Heidari, Golnaz, Ho, Hung Chak, Holla, Ramesh, Househ, Mowafa J, Huang, John J Emmanuel, Ibitoye, Segun Emmanuel M, Ilic, Irena M D, Ilic, Milena D D, Ingram, April D Naghibi, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Itumalla, Ramaiah, Jayaram, Shubha Prakash, Jha, Ravi Prakash, Kahloun, Rim, Kalhor, Rohollah, Kandel, Himal, Kasa, Ayele Semachew, Kavetskyy, Taras A, Kayode, Gbenga A H, Kempen, John H, Khairallah, Moncef, Khalilov, Rovshan Ahmad, Khan, Ejaz Ahmad C, Khanna, Rohit C, Khatib, Mahalaqua Nazli Ahmed, Khoja, Tawfik Ahmed E, Kim, Judy E, Kim, Yun Jin, Kim, Gyu Ri, Kisa, Sezer, Kisa, Adnan, Kosen, Soewarta, Koyanagi, Ai, Kucuk Bicer, Burcu, Kulkarni, Vaman P, Kurmi, Om P, Landires, Iván Charles, Lansingh, Van Charles L, Leasher, Janet L E, LeGrand, Kate E, Leveziel, Nicolas, Limburg, Hans, Liu, Xuefeng, Madhava Kunjathur, Shilpashree, Maleki, Shokofeh, Manafi, Navid, Mansouri, Kaweh, McAlinden, Colm Gebremichael, Meles, Gebrekiros Gebremichael M, Mersha, Abera M, Michalek, Irmina Maria R, Miller, Ted R, Misra, Sanjeev, Mohammad, Yousef, Mohammadi, Seyed Farzad Abdu, Mohammed, Jemal Abdu H, Mokdad, Ali H, Moni, Mohammad Ali Al, Montasir, Ahmed Al R, Morse, Alan R Fentaw, Mulaw, Getahun Fentaw C, Naderi, Mehdi, Naderifar, Homa S, Naidoo, Kovin S, Naimzada, Mukhammad David, Nangia, Vinay, Narasimha Swamy, Sreenivas Muhammad, Naveed, Dr Muhammad, Negash, Hadush Lan, Nguyen, Huong Lan, Nunez-Samudio, Virginia Akpojene, Ogbo, Felix Akpojene, Ogundimu, Kolawole T, Olagunju, Andrew T E, Onwujekwe, Obinna E, Otstavnov, Nikita O, Owolabi, Mayowa O, Pakshir, Keyvan, Panda-Jonas, Songhomitra, Parekh, Utsav, Park, Eun-Cheol, Pasovic, Maja, Pawar, Shrikant, Pesudovs, Konrad, Peto, Tunde Quang, Pham, Hai Quang, Pinheiro, Marina, Podder, Vivek, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur Y, Ramulu, Pradeep Y, Rathi, Priya, Rawaf, Salman Laith, Rawaf, David Laith, Rawal, Lal, Reinig, Nickolas M, Renzaho, Andre M, Rezapour, Aziz L, Robin, Alan L, Rossetti, Luca, Sabour, Siamak, Safi, Sare, Sahebkar, Amirhossein, Sahraian, Mohammad Ali M, Samy, Abdallah M, Sathian, Brijesh, Saya, Ganesh Kumar, Saylan, Mete A, Shaheen, Amira A Ali, Shaikh, Masood Ali T, Shen, Tueng T, Shibuya, Kenji Shibabaw, Shiferaw, Wondimeneh Shibabaw, Shigematsu, Mika, Shin, Jae Il, Silva, Juan Carlos, Silvester, Alexander A, Singh, Jasvinder A, Singhal, Deepika S, Sitorus, Rita S, Skiadaresi, Eirini Yurievich, Skryabin, Valentin Yurievich Aleksandrovna, Skryabina, Anna Aleksandrovna, Soheili, Amin Bekele, Sorrie, Muluken Bekele A R C, Sousa, Raúl A R C T, Sreeramareddy, Chandrashekhar T, Stambolian, Dwight Girma, Tadesse, Eyayou Girma, Tahhan, Nina Ismail, Tareque, Md Ismail, Topouzis, Fotis Xuan, Tran, Bach Xuan, Tsegaye, Gebiyaw K, Tsilimbaris, Miltiadis K, Varma, Rohit, Virgili, Gianni, Vongpradith, Avina Thu, Vu, Giang Thu, Wang, Ya Xing, Wang, Ningli Hailay, Weldemariam, Abrha Hailay K, West, Sheila K Gebeyehu, Wondmeneh, Temesgen Gebeyehu Y, Wong, Tien Y, Yaseri, Mehdi, Yonemoto, Naohiro, Yu, Chuanhua Sergeevich, Zastrozhin, Mikhail Sergeevich, Zhang, Zhi-Jiang R, Zimsen, Stephanie R, Resnikoff, Serge, and Vos, Theo

Published
2021
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10. Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

Author

Bourne, Rupert, Steinmetz, Jaimie D, Flaxman, Seth, Briant, Paul Svitil, Taylor, Hugh R, Resnikoff, Serge, Casson, Robert James, Abdoli, Amir, Abu-Gharbieh, Eman, Afshin, Ashkan, Ahmadieh, Hamid, Akalu, Yonas, Alamneh, Alehegn Aderaw, Alemayehu, Wondu, Alfaar, Ahmed Samir, Alipour, Vahid, Anbesu, Etsay Woldu, Androudi, Sofia, Arabloo, Jalal, Arditi, Aries, Asaad, Malke, Bagli, Eleni, Baig, Atif Amin, Bärnighausen, Till Winfried, Battaglia Parodi, Maurizio, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bijani, Ali, Bikbov, Mukharram, Bottone, Michele, Braithwaite, Tasanee, Bron, Alain M, Butt, Zahid A, Cheng, Ching-Yu, Chu, Dinh-Toi, Cicinelli, Maria Vittoria, Coelho, João M, Dagnew, Baye, Dai, Xiaochen, Dana, Reza, Dandona, Lalit, Dandona, Rakhi, Del Monte, Monte A, Deva, Jenny P, Diaz, Daniel, Djalalinia, Shirin, Dreer, Laura E, Ehrlich, Joshua R, Ellwein, Leon B, Emamian, Mohammad Hassan, Fernandes, Arthur G, Fischer, Florian, Friedman, David S, Furtado, João M, Gaidhane, Abhay Motiramji, Gaidhane, Shilpa, Gazzard, Gus, Gebremichael, Berhe, George, Ronnie, Ghashghaee, Ahmad, Golechha, Mahaveer, Hamidi, Samer, Hammond, Billy Randall, Hartnett, Mary Elizabeth R, Hartono, Risky Kusuma, Hay, Simon I, Heidari, Golnaz, Ho, Hung Chak, Hoang, Chi Linh, Househ, Mowafa, Ibitoye, Segun Emmanuel, Ilic, Irena M, Ilic, Milena D, Ingram, April D, Irvani, Seyed Sina Naghibi, Jha, Ravi Prakash, Kahloun, Rim, Kandel, Himal, Kasa, Ayele Semachew, Kempen, John H, Keramati, Maryam, Khairallah, Moncef, Khan, Ejaz Ahmad, Khanna, Rohit C, Khatib, Mahalaqua Nazli, Kim, Judy E, Kim, Yun Jin, Kisa, Sezer, Kisa, Adnan, Koyanagi, Ai, Kurmi, Om P, Lansingh, Van Charles, Leasher, Janet L, Leveziel, Nicolas, Limburg, Hans, Majdan, Marek, Manafi, Navid, Mansouri, Kaweh, McAlinden, Colm, Mohammadi, Seyed Farzad, Mohammadian-Hafshejani, Abdollah, Mohammadpourhodki, Reza, Mokdad, Ali H, Moosavi, Delaram, Morse, Alan R, Naderi, Mehdi, Naidoo, Kovin S, Nangia, Vinay, Nguyen, Cuong Tat, Nguyen, Huong Lan Thi, Ogundimu, Kolawole, Olagunju, Andrew T, Ostroff, Samuel M, Panda-Jonas, Songhomitra, Pesudovs, Konrad, Peto, Tunde, Quazi Syed, Zahiruddin, Rahman, Mohammad Hifz Ur, Ramulu, Pradeep Y, Rawaf, Salman, Rawaf, David Laith, Reinig, Nickolas, Robin, Alan L, Rossetti, Luca, Safi, Sare, Sahebkar, Amirhossein, Samy, Abdallah M, Saxena, Deepak, Serle, Janet B, Shaikh, Masood Ali, Shen, Tueng T, Shibuya, Kenji, Shin, Jae Il, Silva, Juan Carlos, Silvester, Alexander, Singh, Jasvinder A, Singhal, Deepika, Sitorus, Rita S, Skiadaresi, Eirini, Skirbekk, Vegard, Soheili, Amin, Sousa, Raúl A R C, Spurlock, Emma Elizabeth, Stambolian, Dwight, Taddele, Biruk Wogayehu, Tadesse, Eyayou Girma, Tahhan, Nina, Tareque, Md Ismail, Topouzis, Fotis, Tran, Bach Xuan, Travillian, Ravensara S, Tsilimbaris, Miltiadis K, Varma, Rohit, Virgili, Gianni, Wang, Ya Xing, Wang, Ningli, West, Sheila K, Wong, Tien Y, Zaidi, Zoubida, Zewdie, Kaleab Alemayehu, Jonas, Jost B, and Vos, Theo

Published
2021
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13. SS OCT and OCT-A Findings in Convalescent Inactive Vogt-Koyanagi-Harada Disease.

Author

Aoun, Safa Ben, Ksiaa, Imen, Nefzi, Dhouha, Khochtali, Sana, Jelliti, Bechir, Abroug, Nesrine, and Khairallah, Moncef

Subjects
OPTIC disc edema, VISUAL acuity, URINATION disorders, RHODOPSIN, RETINAL detachment, PROLIFERATIVE vitreoretinopathy, OPTICAL coherence tomography
Abstract

Purpose: This study aimed to determine predictive factors for low final visual acuity in patients with inactive Vogt-Koyanagi-Harada (VKH) disease using Swept-source OCT and OCT-angiography (OCT-A). Methods: We conducted a prospective longitudinal study, including 21 patients (42 eyes), who were followed up for the first 24 months after disease onset. Patients were included at the acute phase and subsequently treated. Sequential qualitative and quantitative changes in OCT and OCT-A were assessed. Analytical statistical methods were employed to determine predictive factors for final visual acuity. Results: Structural alterations including focal parafoveal outer nuclear layer atrophy, ellipsoid zone disruption, interdigitation zone disruption, and irregular and thickened retinal pigment epithelium line were observed in 57.1% of eyes at month 3, with no significant improvement over time. The presence of flow voids at months 6, 12, and 24 was significantly associated with low final visual acuity. Serous retnal detachment at presentation emerged as an independent risk factor for structural changes detected by SS-OCT during the first 2 years of the disease. Optic disc edema was predictive factor for both structural SS-OCT and OCT-A changes. Conclusion: This study underscores the importance of monitoring flow voids to predict final visual acuity and highlights the impact of serous retinal detachment at presentation on structural changes in patients with inactive VKH disease. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Systemic and Ocular Manifestations of Arboviral Infections: A Review.

Author

Khairallah, Moncef, Abroug, Nesrine, Smit, Derrick, Chee, Soon-Phaik, Nabi, Wijden, Yeh, Steven, Smith, Justine R., Ksiaa, Imen, and Cunningham, Emmett

Abstract

PurposeMethodsResultsConclusionTo provide an overview of pre-selected emerging arboviruses (arthropod-borne viruses) that cause ocular inflammation in humans.A comprehensive review of the literature published between 1997 and 2023 was conducted in PubMed database. We describe current insights into epidemiology, systemic and ocular manifestations, diagnosis, treatment, and prognosis of arboviral diseases including West Nile fever, Dengue fever, Chikungunya, Rift Valley fever, Zika, and Yellow fever.Arboviruses refer to a group of ribonucleic acid viruses transmitted to humans by the bite of hematophagous arthropods, mainly mosquitoes. They mostly circulate in tropical and subtropical zones and pose important public health challenges worldwide because of rising incidence, expanding geographic range, and occurrence of prominent outbreaks as a result of climate change, travel, and globalization. The clinical signs associated with infection from these arboviruses are often inapparent, mild, or non-specific, but they may include serious, potentially disabling or life-threatening complications. A wide spectrum of ophthalmic manifestations has been described including conjunctival involvement, anterior uveitis, intermediate uveitis, various forms of posterior uveitis, maculopathy, optic neuropathy, and other neuro-ophthalmic manifestations. Diagnosis of arboviral diseases is confirmed with either real time polymerase chain reaction or serology. Management involves supportive care as there are currently no specific antiviral drug options. Corticosteroids are often used for the treatment of associated ocular inflammation. Most patients have a good visual prognosis, but there may be permanent visual impairment due to ocular structural complications in some. Community-based integrated mosquito management programs and personal protection measures against mosquito bites are the best ways to prevent human infection and disease.Emerging arboviral diseases should be considered in the differential diagnosis of ocular inflammatory conditions in patients living in or returning from endemic regions. Early clinical consideration followed by confirmatory testing can limit or prevent unnecessary treatments for non-arboviral causes of ocular inflammation. Prevention of these infections is crucial. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Pediatric Pars Planitis: A Review.

Author

Khochtali, Sana, Ozdal, Pinar, AlBloushi, Abdulrahman F., Nabi, Wijdène, and Khairallah, Moncef

Subjects
IRIDOCYCLITIS, LITERATURE reviews, MACULAR edema, VISION disorders, PARS plana, DISEASE susceptibility
Abstract

To provide an overview of pediatric pars planitis. Narrative literature review. Pars planitis refers to the idiopathic subset of intermediate uveitis in which there is vitritis along with snowball or snowbank formation occurring in the absence of an associated infection or systemic disease. It is thought to be a T-cell mediated disease with a genetic predisposition. Pars planitis accounts for 5–26.7% of pediatric uveitis cases. Presentation is commonly bilateral but asymmetric, often with insidious onset of floaters and blurred vision. Although pars planitis is known to be a benign form of uveitis in most cases, severe complications secondary to chronic inflammation may arise, with cystoid macular edema being the most common cause of visual morbidity. Mild vitritis in the absence of symptoms, vision loss, or macular edema may be observed. Patients with severe vitritis and/or associated vision-threatening complications require prompt aggressive treatment. A stepladder approach including corticosteroids, immunosuppressive agents, anti‑tumor necrosis factor‑alpha and pars plana vitrectomy and/or laser photocoagulation is the most commonly used method for treatment of pars planitis. Timely diagnosis and adequate treatment of pediatric pars planitis and associated complications are crucial in order to improve visual outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Ocular Manifestations of Flavivirus Infections.

Author

Zina, Sourour Meziou, Hoarau, Gautier, Labetoulle, Marc, Khairallah, Moncef, and Rousseau, Antoine

Subjects
FLAVIVIRAL diseases, JAPANESE encephalitis viruses, WEST Nile virus, YELLOW fever, OCULAR manifestations of general diseases, ENDEMIC diseases
Abstract

Flaviviruses are a group of positive-sense, single-stranded RNA viruses predominantly transmitted by arthropods (mainly mosquitoes) that cause severe endemic infections and epidemics on a global scale. They represent a major cause of systemic morbidity and death and are expanding worldwide. Among this group, dengue fever, the West Nile virus, yellow fever, Japanese Encephalitis, and, recently, the Zika virus have been linked to a spectrum of ocular manifestations. These manifestations encompass subconjunctival hemorrhages and conjunctivitis, anterior and posterior uveitis (inclusive of vitritis, chorioretinitis, and retinal vasculitis), maculopathy, retinal hemorrhages, and optic neuritis. Clinical diagnosis of these infectious diseases is primarily based on epidemiological data, history, systemic symptoms and signs, and the pattern of ocular involvement. Diagnosis confirmation relies on laboratory testing, including RT-PCR and serological testing. Ocular involvement typically follows a self-limited course but can result in irreversible visual impairment. Effective treatments of flavivirus infections are currently unavailable. Prevention remains the mainstay for arthropod vector and zoonotic disease control. Effective vaccines are available only for the yellow fever virus, dengue virus, and Japanese Encephalitis virus. This review comprehensively summarizes the current knowledge regarding the ophthalmic manifestations of the foremost flavivirus-associated human diseases. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Global causes of blindness and distance vision impairment 1990–2020: a systematic review and meta-analysis

Author

Bourne, Rupert, Ackland, Peter, Arditi, Aries, Barkana, Yaniv, Bozkurt, Banu, Braithwaite, Tasanee, Bron, Alain, Budenz, Donald, Cai, Feng, Casson, Robert, Chakravarthy, Usha, Choi, Jaewan, Cicinelli, Maria Vittoria, Congdon, Nathan, Dana, Reza, Dandona, Rakhi, Dandona, Lalit, Das, Aditi, Dekaris, Iva, Del Monte, Monte, deva, Jenny, Dreer, Laura, Ellwein, Leon, Frazier, Marcela, Frick, Kevin, Friedman, David, Furtado, Joao, Gao, Hua, Gazzard, Gus, George, Ronnie, Gichuhi, Stephen, Gonzalez, Victor, Hammond, Billy, Hartnett, Mary Elizabeth, He, Minguang, Hejtmancik, James, Hirai, Flavio, Huang, John, Ingram, April, Javitt, Jonathan, Jonas, Jost, Joslin, Charlotte, Keeffe, Jill, Kempen, John, Khairallah, Moncef, Khanna, Rohit, Kim, Judy, Lambrou, George, Lansingh, Van Charles, Lanzetta, Paolo, Leasher, Janet, Lim, Jennifer, LIMBURG, Hans, Mansouri, Kaweh, Mathew, Anu, Morse, Alan, Munoz, Beatriz, Musch, David, Naidoo, Kovin, Nangia, Vinay, Palaiou, Maria, Parodi, Maurizio Battaglia, Pena, Fernando Yaacov, Pesudovs, Konrad, Peto, Tunde, Quigley, Harry, Raju, Murugesan, Ramulu, Pradeep, Rankin, Zane, Resnikoff, Serge, Reza, Dana, Robin, Alan, Rossetti, Luca, Saaddine, Jinan, Sandar, Mya, Serle, Janet, Shen, Tueng, Shetty, Rajesh, Sieving, Pamela, Silva, Juan Carlos, Silvester, Alex, Sitorus, Rita S., Stambolian, Dwight, Stevens, Gretchen, Taylor, Hugh, Tejedor, Jaime, Tielsch, James, Tsilimbaris, Miltiadis, van Meurs, Jan, Varma, Rohit, Virgili, Gianni, Wang, Ya Xing, Wang, Ning-Li, West, Sheila, Wiedemann, Peter, Wong, Tien, Wormald, Richard, Zheng, Yingfeng, Flaxman, Seth R, Bourne, Rupert R A, Cicinelli, Maria V, Jonas, Jost B, Kempen, John H, Limburg, Hans, Stevens, Gretchen A, Tahhan, Nina, Wong, Tien Y, and Taylor, Hugh R

Published
2017
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27. A pediatric case of West Nile virus chorioretinitis associated with unilateral acute idiopathic maculopathy

Author

Amor, Hajer Ben, Daoud, Marwa, Besbes, Habib, Ksiaa, Imen, Chouchane, Slaheddine, Jelliti, Bechir, Khochtali, Sana, and Khairallah, Moncef

Subjects
West Nile fever -- Case studies -- Complications and side effects, Children -- Diseases, Retinitis pigmentosa -- Case studies -- Causes of, Health
Abstract

Byline: Hajer. Ben Amor, Marwa. Daoud, Habib. Besbes, Imen. Ksiaa, Slaheddine. Chouchane, Bechir. Jelliti, Sana. Khochtali, Moncef. Khairallah We report a pediatric case of unilateral acute idiopathic maculopathy (UAIM) associated [...]

Published
2022

28. Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis

Author

Bourne, Rupert, Ackland, Peter, Arditi, Aries, Barkana, Yaniv, Bozkurt, Banu, BRAITHWAITE, TASANEE, Bron, Alain, Budenz, Donald, Cai, Feng, Casson, Robert, Chakravarthy, Usha, Choi, Jaewan, Cicinelli, Maria Vittoria, Congdon, Nathan, Dana, Reza, Dandona, Rakhi, Dandona, Lalit, Das, Aditi, Dekaris, Iva, Del Monte, Monte, Deva, Jenny, Dreer, Laura, Ellwein, Leon, Frazier, Marcela, Frick, Kevin, Friedman, David, Furtado, Joao, Gao, Hua, Gazzard, Gus, George, Ronnie, Gichuhi, Stephen, Gonzalez, Victor, Hammond, Billy, Hartnett, Mary Elizabeth, He, Minguang, Hejtmancik, James, Hirai, Flavio, Huang, John, Ingram, April, Javitt, Jonathan, Jonas, Jost, Joslin, Charlotte, Keeffe, Jill, Kempen, John, Khairallah, Moncef, Khanna, Rohit, Kim, Judy, Lambrou, George, Lansingh, Van Charles, Lanzetta, Paolo, Leasher, Janet, Lim, Jennifer, LIMBURG, Hans, Mansouri, Kaweh, Mathew, Anu, Morse, Alan, Munoz, Beatriz, Musch, David, Naidoo, Kovin, Nangia, Vinay, PALAIOU, MARIA, Parodi, Maurizio Battaglia, Pena, Fernando Yaacov, Pesudovs, Konrad, Peto, Tunde, Quigley, Harry, Raju, Murugesan, Ramulu, Pradeep, Resnikoff, Serge, Robin, Alan, Rossetti, Luca, Saaddine, Jinan, SANDAR, MYA, Serle, Janet, Shen, Tueng, Shetty, Rajesh, Sieving, Pamela, Silva, Juan Carlos, Silvester, Alex, Sitorus, Rita S, Stambolian, Dwight, Stevens, Gretchen, Taylor, Hugh, Tejedor, Jaime, Tielsch, James, Tsilimbaris, Miltiadis, van Meurs, Jan, Varma, Rohit, Virgili, Gianni, Volmink, Jimmy, Wang, Ya Xing, Wang, Ning-Li, West, Sheila, Wiedemann, Peter, Wong, Tien, Wormald, Richard, Zheng, Yingfeng, Bourne, Rupert R A, Flaxman, Seth R, Braithwaite, Tasanee, Cicinelli, Maria V, Jonas, Jost B, Kempen, John H, Limburg, Hans, Stevens, Gretchen A, Tahhan, Nina, Wong, Tien Y, and Taylor, Hugh R

Published
2017
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31. A Review of Human Ocular RNA Virus Infections Excluding Coronavirus, Human T-Cell Lymphotropic Virus, and Arboviruses.

Author

Smit, Derrick P., Mathew, Dony K., Khairallah, Moncef, Yeh, Steven, and Cunningham Jr, Emmett T.

Subjects
RNA virus infections, HTLV, CORONAVIRUS diseases, IRIDOCYCLITIS, RESPIRATORY syncytial virus infections, ARBOVIRUSES, EYE inflammation
Abstract

We provide an updated review of pre-selected RNA viruses causing ocular inflammation in humans. RNA viruses such as coronaviruses and arboviruses are reviewed elsewhere. A Google Scholar search was conducted to identify recent publications on ocular inflammation caused by the RNA viruses specified here. Human RNA viruses target a wide range of ocular tissues from the anterior to the posterior. Influenza, measles and mumps cause anterior segment manifestations including conjunctivitis and keratitis, while retinitis and optic neuritis may be seen posteriorly. Newcastle disease and RSV cause conjunctivitis, whereas HIV causes characteristic anterior uveitis. Cataracts, microphthalmos, and iris abnormalities are common in congenital Rubella, while Rubella virus is associated with Fuchs uveitis syndrome. Newer technologies make it possible to detect more than one pathogen if present simultaneously. RNA viruses may produce significant ocular morbidity, and care should be taken to investigate ocular symptoms during disease outbreaks. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Posterior Herpetic Uveitis: A Comprehensive Review.

Author

Servillo, Andrea, Berni, Alessandro, Marchese, Alessandro, Bodaghi, Bahram, Khairallah, Moncef, Read, Russell W., and Miserocchi, Elisabetta

Subjects
UVEITIS, IRIDOCYCLITIS, HERPES simplex, POSTHERPETIC neuralgia, SYMPTOMS, OCULAR manifestations of general diseases, VASCULITIS
Abstract

To report and illustrate the main clinical presentations of posterior herpetic uveitis. Narrative review. The ocular manifestations of posterior herpetic uveitis include different clinical presentations. Herpes simplex and varicella zoster can cause acute retinal necrosis, progressive outer retinal necrosis, and non-necrotizing herpetic retinopathies. Cytomegalovirus has been associated with fulminant retinitis with confluent areas of retinal necrosis and retinal hemorrhages, indolent/granular retinitis, and frosted branch angiitis. These diverse clinical presentations are often associated with specific risk factors and different immunological profiles of the host. Herpetic viruses can cause posterior uveitis, presenting various clinical findings. Specific ocular manifestations and the immunological status of the host can help to differentiate the various herpetic entities before laboratory tests confirm the diagnosis. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Swept-source Optical Coherence Tomography Angiography in Active and Scarred Toxoplasmic Retinochoroiditis.

Author

Nabi, Wijden, Ben Amor, Hager, Zina, Sourour, Kadri, Amal, Khochtali, Sana, Abroug, Nesrine, Ksiaa, Imen, and Khairallah, Moncef

Subjects
OPTICAL coherence tomography, RETINAL artery occlusion, ANGIOGRAPHY, SCOTOMA, SCARS
Abstract

To describe optical coherence tomography angiography (OCTA) findings in eyes with active and scarred toxoplasmic retinochoroiditis. OCTA scans in active (25 eyes) and scarred (17 eyes) retinochoroiditis were retrospectively reviewed. In active lesions, OCTA findings included a non-detectable flow signal area in retinal vascular plexuses and choriocapillaris in all 25 eyes (100%), an abnormal intraretinal vascular process in 2 eyes (8%), and an associated area of retinal flow deficit secondary to branch retinal artery occlusion in one eye (4%). In scarred lesions, OCTA findings included a flow deficit area in retinal vascular plexuses and choriocapillaris in all 17 eyes (100%), a visibility of larger deeper choroidal vessels at the level of choriocapillaris in 9 eyes (53%), and a well-defined intraretinal vascular network in one eye (5.9%). Peripapillary scars were associated on OCTA with wedge-shaped loss of radial peripapillary capillaries with corresponding localized retinal nerve fiber layer defect and visual field loss. OCTA allows to non-invasively detect retinal and choroidal vascular changes in active and scarred toxoplasmic retinochoroiditis. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Consensus-based recommendations for optical coherence tomography angiography reporting in uveitis.

Author

Pichi, Francesco, Carreño, Ester, Pavesio, Carlos, Denniston, Alastair K., Grewal, Dilraj S., Deak, Gabor, Khairallah, Moncef, Ruiz-Cruz, Matilde, Rafael de Oliveira Dias, Joao, Adan, Alfredo, Burke, Tomas, Invernizzi, Alessandro, Schlaen, Ariel, Meng Tian, Agarwal, Aniruddha Kishandutt, Tucker, William R., Sen, H. Nida, Lin, Phoebe, Lim, Lyndell L., and Pepple, Kathryn L.

Abstract

Background/aims To establish a consensus in the nomenclature for reporting optical coherence tomography angiography (OCTA findings in uveitis. Methods The modified Delphi process consisted of two rounds of electronic questionnaires, followed by a face-to- face meeting conducted virtually. Twenty-one items were included for discussion. The three main areas of discussion were: wide field OCTA (WF-OCTA), nomenclature of OCTA findings and OCTA signal attenuation assessment and measurement. Seventeen specialists in uveitis and retinal imaging were selected by the executive committee to constitute the OCTA nomenclature in Uveitis Delphi Study Group. The study endpoint was defined by the degree of consensus for each question: ’strong consensus’ was defined as >90% agreement, ’consensus’ as 85%–90% and ’near consensus’ as >80% but <85%. Results There was a strong consensus to apply the term ’wide field’ to OCTA images measuring over 70° of field of view, to use the terms ’flow deficit’ and ’non-detectable flow signal’ to describe abnormal OCTA flow signal secondary to slow flow and to vessels displacement respectively, to use the terms ’loose’ and ’dense’ to describe the appearance of inflammatory choroidal neovascularisation, and to use the percentage of flow signal decrease to measure OCTA ischaemia with a threshold greater than or equal to 30% as a ’large area’. Conclusions This study sets up consensus recommendations for reporting OCTA findings in uveitis by an expert panel, which may prove suitable for use in routine clinical care and clinical trials. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Cytomegalovirus retinitis following corticosteroid overdose for Vogt-Koyanagi-Harada disease

Author

Khochtali, Sana, Mahjoub, Ahmed, Dridi, Tarek, Ksiaa, Imen, Abroug, Nesrine, and Khairallah, Moncef

Subjects
Prednisolone -- Case studies -- Complications and side effects, Retinal diseases -- Case studies -- Diagnosis -- Drug therapy, Meningoencephalitis -- Case studies -- Drug therapy, Overdose -- Case studies -- Complications and side effects, Cytomegalovirus infections -- Case studies -- Diagnosis -- Drug therapy, Health
Abstract

Byline: Sana. Khochtali, Ahmed. Mahjoub, Tarek. Dridi, Imen. Ksiaa, Nesrine. Abroug, Moncef. Khairallah A 33-year-old patient was diagnosed with acute Vogt-Koyanagi-Harada (VKH) disease and was prescribed prednisolone (1 mg/kg/day) and [...]

Published
2020

47. Post-fever retinitis - Newer concepts

Author

Mahendradas, Padmamalini, Kawali, Ankush, Luthra, Saurabh, Srinivasan, Sanjay, Curi, Andre, Maheswari, Shrey, Ksiaa, Imen, and Khairallah, Moncef

Subjects
Retinal diseases -- Development and progression -- Care and treatment, Communicable diseases -- Complications and side effects -- Care and treatment, Health
Abstract

Byline: Padmamalini. Mahendradas, Ankush. Kawali, Saurabh. Luthra, Sanjay. Srinivasan, Andre. Curi, Shrey. Maheswari, Imen. Ksiaa, Moncef. Khairallah Post-fever retinitis (PFR) is an infectious or para-infectious uveitic entity caused by bacterial [...]

Published
2020

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