111 results on '"Knez, Rajna"'
Search Results
2. Medical residents’ and teachers’ perceptions of the digital format of nation-wide didactic courses for psychiatry residents in Sweden: a survey-based observational study
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Knez, Rajna, El Alaoui, Samir, Ivarson, Josefin, Risö Bergerlind, Lise-Lotte, Stasinakis, Sarantos, Ahlgren, Anna-Maria, Maripuu, Martin, Talaee Mofrad, Danielle, Bolander Laksov, Klara, Jayaram-Lindström, Nitya, and Sörman, Karolina
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- 2023
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3. Cross-cultural measurement invariance of the Quality of Life Enjoyment and Satisfaction Questionnaire-Short form across ten countries: the application of Bayesian approximate measurement invariance
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Bagheri, Zahra, Chamanpara, Parisa, Jafari, Peyman, Balhara, Yatan Pal Singh, Arya, Sidharth, Ransing, Ramdas, Đorić, Ana, Knez, Rajna, Thi, Tuong-Vi Vu, Huong, Truong Ngoc, Kafali, Helin Yilmaz, Erzin, Gamze, Vally, Zahir, Chowdhury, Mita Rani Roy, Sharma, Pawan, Shakya, Rabi, Campos, Luís Antônio Monteiro, Szczegielniak, Anna Rebeka, and Stevanović, Dejan
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- 2022
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4. ASD with ADHD vs. ASD and ADHD alone: a study of the QbTest performance and single-dose methylphenidate responding in children and adolescents
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Stevanovic, Dejan, Wentz, Elisabet, Nasic, Salmir, and Knez, Rajna
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- 2022
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5. Cross-cultural similarities and differences in reporting autistic symptoms in toddlers: A study synthesizing M-CHAT(-R) data from ten countries
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Stevanovic, Dejan, Robins, Diana L., Costanzo, Floriana, Fucà, Elisa, Valeri, Giovanni, Vicari, Stefano, Erkuran, Handan Ozek, Yaylaci, Ferhat, Albores-Gallo, Lilia, Gatica-Bahamonde, Gabriel, Gabunia, Maia, Zirakashvili, Medea, Charman, Tony, Samadi, Sayyed Ali, TOH, Teck-Hock, Gayle, Windham, Brennan, Laura, Zorcec, Tatjana, Auza, Alejandra, de Jonge, Maretha, Shoqirat, Noordeen, and Knez, Rajna
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- 2022
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6. Beyond theoretical courses – A study of Swedish psychiatric residents' collegial learning through conversations in the workplace.
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Bolander Laksov, Klara, Knez, Rajna, Steingrimsson, Steinn, El Alaoui, Samir, and Sörman, Karolina
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CAREER development , *ORGANIZATIONAL learning , *PROFESSIONAL employee training , *CONVERSATION analysis , *COMMUNITIES of practice , *THEMATIC analysis , *PSYCHIATRY education - Abstract
Collegial conversations are important for sustainable learning to last beyond a course. Research on collegial conversations and peer learning in the workplace during psychiatric residency courses remains sparse, however. In this study, the aim was to explore residents' opportunities for collegial conversations during and after national courses in psychiatry. Residents in psychiatry completed an online survey including questions on opportunities for collegial conversations in their workplaces. Logistic regression was used for multivariate analysis and thematic content analysis was used for the open-ended answers where a theoretical framework of communities of practice was employed for the interpretation of the findings. The survey was completed by 112 residents out of 725 (15,4%). The participants reported few structured forums for collegial discussion. The results of multivariate analysis suggest that more women than men feel it is advantageous to attend courses with others from the same workplace or from the same group of residents, described here as a team. The analysis of qualitative data identified how opportunities for collegial conversations differ across contexts and the type of values that are attached to team participation in residency courses. This study highlights the importance of collegial conversations as a way to sustain the learning from residency courses into the workplace. By learning about residents' perceptions of collegial conversations during and after courses, teachers and directors may be more able to support residents' lifelong learning and professional development. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Determinants of adolescents' pro-sustainable behavior: a systematic literature review using PRISMA.
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Bhattarai, Prakash C., Shrestha, Richan, Ray, Subhasis, and Knez, Rajna
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CLIMATE change mitigation ,GREEN behavior ,TEENAGERS ,QUANTITATIVE research ,MIXED methods research - Abstract
Climate change is a serious contemporary issue around the world. Adolescents are mostly affected due to climate change. Thus, they are expected to behave in an environmentally appropriate manner, which requires the identification of factors influencing pro-sustainable behavior/pro-environmental behavior. The literature offers a wide range of factors influencing adolescents' pro-sustainable behavior; nonetheless, these factors are not provided with some common themes. Furthermore, no study integrates dispersed research of the area with a comprehensive systematic review. With this consideration, a systematic review was carried out to find comprehensive factors influencing the pro-sustainable behavior of adolescents. For the review, all 21 interdisciplinary studies on factors influencing adolescents' ecological behavior, published between 2010 and 2023 and indexed in Scopus and Web of Science, were analyzed. The analysis revealed that the number of studies in the area increased after 2020, especially in developed countries, and most studies utilized quantitative research methods. The identified key factors influencing adolescents' pro-environmental behavior are categorized into demographic, internal, and external factors. The findings can be helpful for future researchers to have rigorous discourse on the issue and expand the research in developing countries using mixed methods research. The policy maker can use findings to motivate adolescents to participate in climate change mitigation. [ABSTRACT FROM AUTHOR]
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- 2024
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8. Can daily internet use time screen for problematic internet use among college students? A receiver operator characteristic curve-based multi-country study
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Yatan Pal Singh, Balhara, Singh, Swarndeep, Doric, Ana, Stevanovic, Dejan, Knez, Rajna, Roy Chowdhury, Mita Rani, Kafali, Helin Yilmaz, Sharma, Pawan, Vally, Zahir, Vi Vu, Tuong, Arya, Sidharth, Mahendru, Aishita, Ransing, Ramdas, Erzin, Gamze, and Le, Huynh Le Thi Cam Hong
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- 2020
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9. Neurodevelopmental problems, general health and academic achievements in a school‐based cohort of 11‐year‐old Swedish children.
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Landgren, Valdemar, Svensson, Leif, Törnhage, Carl‐Johan, Theodosious, Michail, Gillberg, Christopher, Johnson, Mats, Knez, Rajna, and Landgren, Magnus
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ACADEMIC achievement ,NEURAL development ,NATIONAL competency-based educational tests ,NEUROPSYCHOLOGICAL tests ,STUDENT records - Abstract
Aim: Assessing rates of neurodevelopmental problems (NDPs) in 11‐year‐old children and possible association with other health complaints and school performance. Methods: In‐school study of 11‐year‐old children as an add‐on assessment to the 4th grade regular health check‐up, comprising a structured physical neurodevelopmental examination, neuropsychological assessment, behavioural ratings, maternal interview, review of medical records and academic achievements. Results: Out of 348 children recruited from eight schools, 223 (64%) participated. Any physical condition was found in 102/222 (46%), most commonly atopy (18%). One in five had a BMI z‐score >2 standard deviations over the reference mean. One or more NDP was found in 86/221 (40%) children. The number of failed national tests correlated positively with NDP severity rated with the clinical global impression severity instrument (Spearman's r = 0.41, p < 0.001). The majority of participants with failed national tests, also had co‐occurring health complaints (≥2 of: stomach or extremity ache, headache, difficulties sleeping, internalising symptoms or obesity) and NDPs. Conclusion: Health complaints, physical conditions and NDPs are very common in 11‐year‐old children and warrant adequately staffed, thoroughly equipped school healthcare services. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Posttraumatic stress disorder symptoms among trauma-exposed adolescents from low- and middle-income countries
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Stupar, Dusko, Stevanovic, Dejan, Vostanis, Panos, Atilola, Olayinka, Moreira, Paulo, Dodig-Curkovic, Katarina, Franic, Tomislav, Doric, Ana, Davidovic, Nikolina, Avicenna, Mohamad, Multazam, Isa Noor, Nussbaum, Laura, Thabet, Abdul Aziz, Ubalde, Dino, Petrov, Petar, Deljkovic, Azra, Monteiro, Antonio Luis, Ribas, Adriana, Jovanovic, Mirjana, Joana, Oliveira, and Knez, Rajna
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- 2021
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11. Locus of control, negative live events and psychopathological symptoms in collectivist adolescents
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Atilola, Olayinka, Stevanovic, Dejan, Avicenna, Mohamad, Balhara, Yatan Pal Singh, Franic, Tomislav, Knez, Rajna, Vostanis, Panos, Dodig-Ćurković, Katarina, Davidovic, Nikolina, Ana, Nikšić, Paulo, Moreira, Multazam Noor, Isa, Monteiro, Luis Antonio, Ribas, Adriana, Stupar, Dusko, Deljkovic, Azra, Nussbaum, Laura, Thabet, Abdelaziz, Ubalde, Dino, Petrov, Petar, Olanrewaju, Oladimeji, Bolanle, Lotsu, Moreira, Paulo, Vaz, João Machado, Djoric, Ana, and Campos, Monteiro Luis Antonio
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- 2020
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12. Assessing the symptoms of Internet Gaming Disorder among college/university students: An international validation study of a self-report
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Stevanović Dejan, Đorić Ana, Balhara Yatan Pal Singh, Ćirović Nikola, Arya Sidharth, Ransing Ramdas, Thi Tuong-Vi Vu, Huong Truong Ngoc, Tadić Ivana, Jović Jelena, Radovanović Saša, Kafali Yilmaz Helin, Erzin Gamze, Zahir Vally, Chowdhury Mita Rani Roy, Sharma Pawan, Shakya Rabi, Moreira Paulo, Olayinka Atilola, Mohamad Avicenna, Campos Monteiro Antônio Luís, Campos Pedro de Abreu Monteiro, Moreira Silva Cristiane, Tavares Jose Carlos, Buoli Massimiliano, Burkauskas Julius, Ivanovic Iva, Szczegielniak Anna Rebeka, and Knez Rajna
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internet gaming ,igd ,cross-cultural equivalence ,Psychology ,BF1-990 - Abstract
The present study evaluated the psychometric properties of a self-report scale for assessing Internet Gaming Disorder (IGD) symptoms according to the DSM–5 and ICD–11 among 3270 college/university students (2095 [64.1%] females; age mean 21.6 [3.1] years) from different countries worldwide. Croatian, English, Polish, Portuguese, Serbian, Turkish, and Vietnamese versions of the scale were tested. The study showed that symptoms of IGD could be measured as a single underlying factor among college/university students. A nine item symptom scale following DSM–5, and a short four-item scale representing the main ICD–11 symptoms, had sound internal consistency and construct validity. Three symptom-items were found non-invariant across the language samples (i.e., preoccupation with on-line gaming, loss of interests in previous hobbies and entertainment, and the use of gaming to relieve negative moods). This study provides initial evidence for assessing IGD symptoms among college/university students and will hopefully foster further research into gaming addiction in this population worldwide especially with taking into account language/cultural differences. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 179002]
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- 2020
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13. Correlates of Problematic Internet Use among college and university students in eight countries: An international cross-sectional study
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Pal Singh Balhara, Yatan, Doric, Ana, Stevanovic, Dejan, Knez, Rajna, Singh, Swarndeep, Roy Chowdhury, Mita Rani, Kafali, Helin Yilmaz, Sharma, Pawan, Vally, Zahir, Vi Vu, Tuong, Arya, Sidharth, Mahendru, Aishita, Ransing, Ramdas, Erzin, Gamze, and Le Thi Cam Hong Le, Huynh
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- 2019
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14. Evaluation of 6 years of eHealth data in the alcohol use disorder field indicates improved efficacy of care.
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Wallden, Mats, Dahlberg, Gunnar, Månflod, Johan, Knez, Rajna, Winkvist, Maria, Zetterström, Andreas, Andersson, Karl, Hämäläinen, Markku D., and Nyberg, Fred
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ALCOHOLISM ,COVID-19 pandemic ,CAREGIVERS ,DATA warehousing ,ARTIFICIAL intelligence ,DATA libraries ,WEB archives - Abstract
Background: Predictive eHealth tools will change the field of medicine, however long-term data is scarce. Here, we report findings on data collected over 6 years with an AI-based eHealth system for supporting the treatment of alcohol use disorder. Methods: Since the deployment of Previct Alcohol, structured data has been archived in a data warehouse, currently comprising 505,641 patient days. The frequencies of relapse and caregiver-patient messaging over time was studied. The effects of both introducing an AI-driven relapse prediction tool and the COVID-19 pandemic were analyzed. Results: The relapse frequency per patient day among Previct Alcohol users was 0.28 in 2016, 0.22 in 2020 and 0.25 in 2022 with no drastic change during COVID-19. When a relapse was predicted, the actual occurrence of relapse in the days immediately after was found to be above average. Additionally, there was a noticeable increase in caregiver interactions following these predictions. When caregivers were not informed of these predictions, the risk of relapse was found to be higher compared to when the prediction tool was actively being used. The prediction tool decreased the relapse risk by 9% for relapses that were of short duration and by 18% for relapses that lasted more than 3 days. Conclusions: The eHealth system Previct Alcohol allows for high resolution measurements, enabling precise identifications of relapse patterns and follow up on individual and population-based alcohol use disorder treatment. eHealth relapse prediction aids the caregiver to act timely, which reduces, delays, and shortens relapses. [ABSTRACT FROM AUTHOR]
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- 2024
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15. The Structure and Diagnostic Accuracy of the QbTest in Pediatric ADHD: A Retrospective Clinical Study.
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Stevanovic, Dejan, Nasic, Salmir, Doric, Ana, Wentz, Elisabet, and Knez, Rajna
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CONTINUOUS performance test ,ATTENTION-deficit hyperactivity disorder ,MOTION analysis ,PRINCIPAL components analysis - Abstract
Objective: The QbTest that combines a continuous performance task (CPT) with a motion-tracking system may help identify attention deficit hyperactivity disorder (ADHD). This study examined the structure and diagnostic ability of the QbTest in children and adolescents. Method: Retrospective data from 1,274 children and adolescents were analyzed. The study assessed data on a principal component analysis (PCA), sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Results: The QbActivity component included the variables micro-events, distance, area, and time active; the QbImpulsivity included normalized commissions and commissions (anticipatory errors were added in a version for 6–12-year-olds only); and the QbInattention included omissions, reaction time, and reaction time variation. Sensitivity ranged between 22% and 50%, specificity 79% and 96%, PPVs 40% and 95%, and NPVs 24% and 66%. Conclusion: The structure of the QbTest with three cardinal parameters and nine/ten CPT and motion analysis variables was supported. The diagnostic accuracy was found to be poor to moderate. Given that this is a retrospective study, the interpretation of diagnostic accuracy should be considered within this context. [ABSTRACT FROM AUTHOR]
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- 2023
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16. Satisfaction with psychiatric in-patient care as rated by patients at discharge from hospitals in 11 countries
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Krupchanka, Dzmitry, Khalifeh, Hind, Abdulmalik, Jibril, Ardila-Gómez, Sara, Armiya’u, Aishatu Yusha’u, Banjac, Visnja, Baranov, Alexey, Bezborodovs, Nikita, Brecic, Petrana, Čavajda, Zoran, de Girolamo, Giovanni, Denisenko, Maria, Dickens, Howard Akena, Dujmovic, Josip, Ergovic Novotny, Dubravka, Fedotov, Ilya, Fernández, Marina A., Frankova, Iryna, Gasparovic, Marta, Giurgi-Oncu, Catalina, Grahovac, Tanja, James, Bawo O., Jomli, Rabaa, Kekin, Ivana, Knez, Rajna, Lanfredi, Mariangela, Lassman, Francesca, Mehta, Nisha, Nacef, Fethi, Nawka, Alexander, Nemirovsky, Martin, Ola, Bolanle Adeyemi, Oshodi, Yewande O., Ouali, Uta, Peharda, Tomislav, Razic Pavicic, Andrea, Rojnic Kuzman, Martina, Roventa, Costin, Shamenov, Rinat, Smirnova, Daria, Smoljanic, Davorka, Spikina, Anna, Thornicroft, Amalia, Tomicevic, Marko, Vidovic, Domagoj, Williams, Paul, Yakovleva, Yulia, Zhabenko, Olena, Zhilyaeva, Tatiana, Zivkovic, Maja, Thornicroft, Graham, and Sartorius, Norman
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- 2017
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17. Prevalence of chronic pain in children and adolescents with psychiatric conditions.
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Lundqvist, Sara, Knez, Rajna, Nagy, Karin, Nasic, Salmir, Kerekes, Nóra, and Kantzer, Anne‐Katrin
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CHRONIC pain ,COMPARATIVE studies ,DISEASE prevalence ,QUESTIONNAIRES ,RESEARCH funding ,HEADACHE ,ABDOMINAL pain ,CHILDREN ,ADOLESCENCE - Abstract
The prevalence of pain in children and adolescents with psychiatric conditions is rarely investigated. The aims of the current study were to (a) describe the prevalence of headaches and abdominal pain in children and adolescents with psychiatric conditions, (b) compare the prevalence of pain in children and adolescents with psychiatric conditions with that in the general population, and (c) investigate the associations between pain experience and different types of psychiatric diagnoses. Families with a child aged 6–15 years who had been referred to a child and adolescent psychiatry (CAP) clinic completed the Chronic Pain in Psychiatric Conditions questionnaire. Information about the child/adolescent's psychiatric diagnosis(es) was extracted from the CAP clinic's medical records. The children and adolescents included in the study were divided into diagnostic groups and compared. Their data were also compared with data of control subjects collected during a previous study of the general population. Abdominal pain was more common among girls with a psychiatric diagnosis (85%) than in the matched control population (62%, p = 0.031). Children and adolescents with neurodevelopmental diagnoses had a higher prevalence of abdominal pain than children and adolescents with other psychiatric diagnoses. Pain conditions in children and adolescents with a psychiatric diagnosis are common and must be addressed. [ABSTRACT FROM AUTHOR]
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- 2023
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18. Problematic Internet Use and Its Correlates Among Students from Three Medical Schools Across Three Countries
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Balhara, Yatan Pal Singh, Gupta, Rishab, Atilola, Olayinka, Knez, Rajna, Mohorović, Tonka, Gajdhar, Wamique, Javed, Ahmed O., and Lal, Rakesh
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- 2015
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19. Orexin/hypocretin system dysfunction in patients with Takotsubo syndrome : A novel pathophysiological explanation
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Knez, Rajna, Niksic, Milan, and Omerovic, Elmir
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Kardiologi ,orexin ,COVID-19 ,Cardiac and Cardiovascular Systems ,hypocretin ,hypothalamus ,Takotsubo syndrome - Abstract
Takotsubo syndrome (TTS) is an acute heart failure syndrome. Emotional or physical stressors are believed to precipitate TTS, while the pathophysiological mechanism is not yet completely understood. During the coronavirus disease (COVID-19) pandemic, an increased incidence of TTS has been reported in some countries; however, the precise pathophysiological mechanism for developing TTS with acute COVID-19 infection is unknown. Nevertheless, observing the symptoms of COVID-19 might lead to new perspectives in understanding TTS pathophysiology, as some of the symptoms of the COVID-19 infection could be assessed in the context of an orexin/hypocretin-system dysfunction. Orexin/hypocretin is a cardiorespiratory neuromodulator that acts on two orexin receptors widely distributed in the brain and peripheral tissues. In COVID-19 patients, autoantibodies against one of these orexin receptors have been reported. Orexin-system dysfunction affects a variety of systems in an organism. Here, we review the influence of orexin-system dysfunction on the cardiovascular system to propose its connection with TTS. We propose that orexin-system dysfunction is a potential novel explanation for the pathophysiology of TTS due to direct or indirect dynamics of orexin signaling, which could influence cardiac contractility. This is in line with the conceptualization of TTS as a cardiovascular syndrome rather than merely a cardiac abnormality or cardiomyopathy. To the best of our knowledge, this is the first publication to present a plausible connection between TTS and orexin-system dysfunction. We hope that this novel hypothesis will inspire comprehensive studies regarding orexin's role in TTS pathophysiology. Furthermore, confirmation of this plausible pathophysiological mechanism could contribute to the development of orexin-based therapeutics in the treatment and prevention of TTS. Copyright CC BY 4.0© 2022 Knez, Niksic and Omerovic.Correspondence: Rajna Knez, rajna.knez@gu.seThis study was financed by grants from the Swedish state under the agreement between the Swedish government and the county councils, the ALF-agreement, the Swedish Heart-Lung Foundation and the Swedish Scientific Council.
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- 2022
20. Pedagoški izazovi u provođenju edukacije specijalizanata psihijatrije tijekom pandemije COVID-19: što možemo primijeniti u budućim edukativnim aktivnostima
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Knez, Rajna
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COVID-19 ,eucation, distance ,internship and residency ,psychiatry ,education ,e-ucenje ,psihijatrija ,specijalističko usavršavanje - Abstract
The coronavirus disease 2019 (COVID-19) pandemic has challenged and almost completely disrupted the previous teaching system, based mainly on teachers’ and learners’ physical presence. This impact has forced educators to identify alternative learning models and begin utilizing new approaches, often without detailed analysis or thorough, systematic planning. The current literature review aims to reveal some of the greatest pedagogical challenges in remotely teaching psychiatry residents during the pandemic. This mini-review’s results may help in developing additional pedagogical techniques and key applications for educational activities to teach psychiatry residents, as well as to suggest directions for future psychiatry resident education., Pandemija koronavirusne bolesti 2019. (COVID-19) u značajnom je obimu onemogućila provođenje uobičajenih edukacijskih aktivnosti što je, izmedu ostalog, rezultiralo i primjenom novih modela učenja. Međutim, promjene koje su uslijedile često su implementirane bez detaljne prethodne analize i temeljitog, sustavnog planiranja njihovog provođenja. Ovaj kratki pregled literature ima za cilj identificirati neke od glavnih pedagoških izazova u edukaciji specijalizanata psihijatrije tijekom aktualne pandemije. Rezultati ovog preglednog članka mogu pomoći pri razvoju dodatnih pedagoških tehnika i inovativnih alata za korištenje u budućim obrazovnim aktivnostima te pridonijeti planiranju organizacije specijalističkog obrazovanja iz psihijatrije.
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- 2022
21. Orexin/Hypocretin System Dysfunction in ESSENCE (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations).
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Knez, Rajna, Stevanovic, Dejan, Fernell, Elisabeth, and Gillberg, Christopher
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EXECUTIVE function , *NEURAL development , *AUTISM spectrum disorders , *EMOTIONAL eating , *NEUROLOGICAL disorders , *MOOD (Psychology) - Abstract
Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations (ESSENCE) is an umbrella term covering a wide range of neurodevelopmental difficulties and disorders. Thus, ESSENCE includes attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and other neurodevelopmental disorders (NDDs) and difficulties, with a variety of symptoms in cognitive, motor, sensory, social, arousal, regulatory, emotional, and behavioral developmental domains, frequently co-occurring and likely having partly common neurobiological substrates. The ESSENCE concept is a clinical paradigm that promotes organizing NDDs in everyday clinical practice according to their coexistence, symptom dimensions overlapping, and treatment possibilities. Despite increased knowledge regarding NDDs, the neurobiological mechanisms that underlie them and other ESSENCE-related problems, are not well understood. With its wide range of neural circuits and interactions with numerous neurotransmitters, the orexin/hypocretin system (Orx-S) is possibly associated with a variety of neurocognitive, psychobiological, neuroendocrine, and physiological functions and behaviors. Dysfunction of Orx-S has been implicated in various psychiatric and neurological disorders. This article provides an overview of Orx-S dysfunctions' possible involvement in the development, presentation, and maintenance of ESSENCE. We provide a focused review of current research evidence linking orexin neuropeptides with specific clinical NDDs symptoms, mostly in ADHD and ASD, within the Research Domain Criteria (RDoC) framework. We propose that Orx-S dysfunction might have an important role in some of these neurodevelopmental symptom domains, such as arousal, wakefulness, sleep, motor and sensory processing, mood and emotional regulation, fear processing, reward, feeding, attention, executive functions, and sociability. Our perspective is presented from a clinical point of view. Further, more thorough systematic reviews are needed as well as planning of extensive new research into the Orx-S's role in ESSENCE, especially considering RDoC elements. [ABSTRACT FROM AUTHOR]
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- 2022
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22. The ESSENCE-Questionnaire in Medical Records Screening for Neurodevelopmental Symptoms/Problems: Utility and Clinical Validity.
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Landgren, Valdemar, Soltis, Zohar Raanan, Svensson, Emma, Theodosiou, Michail, Landgren, Magnus, and Knez, Rajna
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SCHOOL health services ,MEDICAL screening ,MEDICAL records ,NEURAL development ,INTRACLASS correlation - Abstract
Purpose: Determine the prevalence of symptoms of neurodevelopmental problems (NDPs) with a semi-structured review of fourth grade students' medical records, its interrater agreement and validity as compared with clinical assessment. Methods: A school-based sample of 11-year-old children provided child health care (CHC) records and school health care (SHC) records. A pediatric neurologist, child psychiatrist and an adult psychiatrist scored the records, with the "Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations-Questionnaire" (ESSENCE-Q, 12 items scored 0– 2, summary score range 0– 24). Agreement was measured with model-based kappa and intraclass correlation coefficient (ICC). Ratings were validated against a multidisciplinary assessment involving a physician, psychologist, teacher- and parental behavioral rating scales rendering a clinical global impression severity rating (CGI-S, range 1– 7) of NDPs. Results: Out of 223 participants, medical charts were available from 201, of whom 169 were rated by all three raters. Kappa agreement was moderate/strong (~0.8) for 7 of the 12 questionnaire items. Measured with the ICC, concordance in the summary score was good for agreement (~0.8) and excellent (~0.9) for consistency. Test–retest reliability was excellent (ICC = ~0.9). Area under the curve for the ESSENCE-Q in predicting clinical-level problems (CGI ≥ 4) was ~80% for all three raters, albeit with differing optimal cutoffs. Conclusion: Using the ESSENCE-Q as a template, NDPs appear to be common in medical records, are identified reliably, and predict clinical-level concern. Medical records screening may facilitate a structured review of medical records in work-ups or be applied in conjunction with other screening measures for neurodevelopmental disorders. However, differences in calibration currently preclude defining a universal cutoff for using the ESSENCE-Q for medical records screening. [ABSTRACT FROM AUTHOR]
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- 2022
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23. The Croatian Version of the Pediatric Quality of Life Inventory (PedsQL™) Family Impact Module: Cross-Cultural Adaptation and Psychometric Evaluation
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Knez, Rajna, Stevanovic, Dejan, Vulić-Prtorić, Anita, Vlašić-Cicvarić, Inge, and Peršić, Mladen
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- 2015
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24. The associations between ADHD, pain, inflammation, and quality of life in children and adolescents—a clinical study protocol.
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Kerekes, Nóra, Lundqvist, Sara, Schubert Hjalmarsson, Elke, Torinsson Naluai, Åsa, Kantzer, Anne-Katrin, and Knez, Rajna
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YOUTH with attention-deficit hyperactivity disorder ,MEDICAL protocols ,QUALITY of life ,ATTENTION-deficit hyperactivity disorder ,TEENAGERS ,BIRTHPARENTS ,SOMATIC embryogenesis ,PAIN threshold - Abstract
New research shows that the prevalence of neurodevelopmental disorders, such as attention-deficit/hyperactivity disorder (ADHD), is increased in children and adolescents as well as in adults with chronic pain, compared to those without chronic pain. Children and adolescents with ADHD also have an increased incidence of various physical conditions associated with pain, and they more frequently suffer from inflammatory diseases. Moreover, parents of children with ADHD can often suffer from pain conditions. These epidemiological and clinical observations form the scientific basis of our study, which aims to map the relationships between ADHD, altered pain experiences/central sensitization, and inflammation in children and adolescents. We will investigate the presence of central sensitization in children and adolescents with newly diagnosed ADHD and compare it with those who have not been diagnosed with ADHD. Participants (and their biological parents) will complete surveys about their somatic health, pain experience, and quality of life. Biological samples (saliva and stool) will be collected, aiming to utilize proteome and metabolome data to discover disease mechanisms and to predict, prevent and treat them. The results from our investigation should enable an expanded understanding of the pathophysiology behind both ADHD and pain/central sensitization. Presently, there are no established protocols for addressing psychiatric symptoms when examining patients with pain conditions in a somatic care setting, nor is there any knowledge of offering patients with ADHD or other neurodevelopmental disorders adapted treatments for pain conditions. Our results, therefore, can contribute to the development of new treatment strategies for pathological pain conditions in children and adolescents with ADHD. They may also increase awareness about and provide opportunities for the treatment of attention and impulse control problems in children and adolescents with pain syndromes. [ABSTRACT FROM AUTHOR]
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- 2022
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25. The ESSENCE-Questionnaire for Neurodevelopmental Problems – A Swedish School-Based Validation Study in 11-Year-Old Children.
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Landgren, Valdemar, Svensson, Leif, Knez, Rajna, Theodosiou, Michail, Gillberg, Christopher, Fernell, Elisabeth, Landgren, Magnus, and Johnson, Mats
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NEURAL development ,RECEIVER operating characteristic curves ,CHILDREN with developmental disabilities ,NATIONAL competency-based educational tests ,PREDICTIVE validity ,PEOPLE with disabilities - Abstract
Purpose: To determine the prevalence of parent-rated developmental concern using the ESSENCE-Q (Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations-Questionnaire, 12-items, score range 0– 24) and to ascertain the predictive validity and optimal cutoff level of the instrument in a school-based sample of 11-year-old children. Methods: In a cross-sectional, school-based study, participants underwent a clinical assessment by a physician and a psychologist, teachers and parents completed the SDQ (Strength and Difficulties Questionnaire), medical health records and national tests were reviewed, and parents independently completed the ESSENCE-Q. In a case-conference outcomes were defined as a) the need for further clinical work-up due to suspected neurodevelopmental problems (NDPs) and b) degree of investigator-rated symptoms/impairment from NDPs on the CGI-S (Clinical Global Impression-Severity instrument, range 1– 7, 4– 7 defined as clinically symptomatic). Classification and optimal cutoffs of the ESSENCE-Q were determined using ROC (Receiver Operating Characteristic) analysis. Results: Out of 343 eligible children, 223 enrolled, of whom 173 (50% of all eligible) had a parent-rated ESSENCE-Q. At least one of the 12 possible concerns was reported by parents of 36% of participants. Overall, in 101 (57%) participants a work-up was warranted, and 64 (37%) were clinically symptomatic from NDPs. The AUC of the ESSENCE-Q in detecting need for work-up was 0.70 (95% confidence interval [CI] 0.63– 0.77), and the AUC in detecting clinically symptomatic participants was 0.82 (95% CI 0.76– 0.88). ESSENCE-Q ratings correlated positively with CGI-S scores (r=0.48, p< 0.05). A cutoff of ≥ 3 had the highest accuracy (78%) with a negative predictive value of 82%. Ratings > 6 conferred few false positives cases with positive likelihood ratios > 10 and positive predictive values of 86% or more. Significance: This study of the ESSENCE-Q in 11-year-old children suggests it might be an acceptable instrument for screening of NDPs in children in middle school, optimally in conjunction with other methods. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
26. External locus-of-control partially mediates the association between cumulative trauma exposure and posttraumatic stress symptoms among adolescents from diverse background
- Author
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Atilola, Olayinka, Dodig-Ćurković, Katarina, Franić, Tomislav, Đorić, Ana, Davidović, Nikolina, and Knez, Rajna
- Subjects
Adolescents ,external locus of control ,meditational analyses ,PTSD - Abstract
Background and Objectives: Locus of control (LOC) is a modifiable mediator of symptoms of posttraumatic stress disorder (PTSD) among traumatized individuals and a potential target of intervention. Compared with studies involving adults, the potential mediation effect of LOC on PTSD symptoms among trauma-exposed children and adolescents is relatively under-explored. This study, therefore, assessed the mediation effects of LOC on the association between lifetime cumulative trauma and PTSD symptoms among a large cohort of adolescents from different cultural background. Design: Cross-sectional study. Methods: LOC was determined using the Multi- Dimension Locus of Control Scale ; Posttraumatic stress symptoms using the UCLA PTSD Reaction Index ; and other significant negative life events using the Life Events Checklist. Results: Among 3826 adolescents who completed the study, external LOC explained 24% of variance (R 2 =.24 ; F2, 3823 = 619.01 ; p
- Published
- 2021
27. Expecting parents' perceptions of the digital parental support "childbirth journey" constructed as a serious game—an intervention study.
- Author
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Bäckström, Caroline, Rolfson, Tanja, Engström, Henrik, Knez, Rajna, and Larsson, Margaretha
- Published
- 2022
- Full Text
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28. Locus of control, negative live events and psychopathological symptoms in collectivist adolescents
- Author
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Moreira, Paulo, Vaz, João Machado, Stevanović, Dejan, Atilola, Olayinka, Dodig-Ćurković, Katarina, Franić, Tomislav, Djorić, Ana, Davidović, Nikolina, Avicenna, Mohamad, Multazam Noor, Isa, Campos, Monteiro Luis Antonio, Ribas, Adriana, Stupar, Duško, Deljković, Azra, Nussbaum, Laura, Thabet, Abdelaziz, Ubalde, Dino, Petrov, Petar, Vostanis, Panos, Knez, Rajna, and Balhara, Yatan Pal Singh
- Subjects
Collectivism ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Psihijatrija ,Locus of control ,Symptoms ,Negative events ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Psychiatry ,Adolescents - Abstract
Current research trend is the identification of psychosocial variables that moderate and/or mediate the association between stressors and psychopathological symptoms. Research has shown Locus of Control (LoC) is a key cognitive component of this psychological process in adolescents from individualist cultures. It is unclear whether this finding can be generalized to collectivist adolescents given that LoC is argued to be a culturally relative construct. The study examined the moderating and mediating effects of LoC on the relationship between negative events and psychopathological symptoms (anxiety and depressive symptoms) in adolescents from collectivist countries (n = 2800). Consistent with prior research, negative life events and external LoC were associated with more psychopathological symptoms. Unlike past studies with samples from individualist countries, the study did not produce clear evidence that LoC moderated or mediated this relationship. Results are discussed in terms of cultural differences in the (un)desirability of external control.
- Published
- 2020
29. Locus of control, negative live events and psychopathological symptoms in collectivist
- Author
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Moreira, Paulo, Vaz, João Machado, Stevanovic, Dejan, Atilola, Olayinka, Dodig-Ćurković, Katarina, Franic, Tomislav, Djoric, Ana, Davidovic, Nikolina, Avicenna, Mohamad, Multazam Noor, Isa, Campos, Monteiro Luis Antonio, Ribas, Adriana, Stupar, Dusko, Deljkovic, Azra, Nussbaum, Laura, Thabet, Abdelaziz, Ubalde, Dino, Petrov, Petar, Vostanis, Panos, Knez, Rajna, Balhara, Yatan Pal Singh, Dodig- Ćurković, Katarina, Ana, Nikšić, Paulo, Moreira, Monteiro, Luis Antonio, Olanrewaju, Oladimeji, and Bolanle, Lotsu
- Subjects
Locus of control ,Symptoms ,Negative events ,Collectivism ,Adolescents - Abstract
current research trend is the identification of psychosocial variables that moderate and/or mediate the association between stressors and psychopathological symptoms. Research has shown Locus of Control (LoC) is a key cognitive component of this psychological process in adolescents from individualist cultures. It is unclear whether this finding can be generalized to collectivist adolescents given that LoC is argued to be a culturally relative construct. The study examined the moderating and mediating effects of LoC on the relationship between negative events and psychopathological symptoms (anxiety and depressive symptoms) in adolescents from collectivist countries (n = 2800). Consistent with prior research, negative life events and external LoC were associated with more psychopathological symptoms. Unlike past studies with samples from individualist countries, the study did not produce clear evidence that LoC moderated or mediated this relationship. Results are discussed in terms of cultural differences in the (un)desirability of external control.
- Published
- 2020
30. Migracija hrvatskih liječnika u globalnom kontekstu
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Gruber, Ema, Knez, Rajna, Martic Biocina, Sanja, Starcevic, Branka, Moravek, Davor, Musovic, Martina, and Sarajlic Vukovic, Iris
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integracija ,migracija ,liječnici ,psihijatri - Abstract
As the global health care workforce faces a shortage, several EU nations focus on employing foreign-trained physicians. So much so, that in some countries of the EU, the percentage of foreign-trained physicians has reached 30 % and the percentage of foreigntrained psychiatrists has risen to 40 %. After Croatia entered the EU, together with a significant number of other Croatian citizens, a great proportion of Croatian physicians emigrated. Currently, Croatia is among the three EU countries from which the most physicians emigrate. There are both economic and non-economic factors that are influence individuals’ choice to emigrate. Benefits of emigration for Croatian physicians are high satisfaction with life standard, income, professional development, and better work conditions. However, there are also clear psychological costs involved, which hinder both the emigrants and their families, and make building of a social network and integration into society difficult. These are: moving away from family members, friends and a familiar environment, mastering another language, finding work opportunities for partners, adjusting to life in another country under discrimination by colleagues, patients and the general public. Countries of immigration face challenges with foreign-trained physicians because of their native linguistic and cultural background. Language proficiency training and national familiarization programs can improve integration of immigrant physicians and their families. In recognition that national skill shortages can cause disbalance on a global level, the WHO calls on high-income countries to strive for self-sufficiency, through educating, retaining, and sustaining enough physicians to staff their own health care systems.
- Published
- 2020
31. The pedagogical challenges of teaching psychiatry residents during the COVID-19 pandemic: Applications for future educational activities.
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Knez, Rajna
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- *
COVID-19 pandemic , *PSYCHIATRY - Abstract
The coronavirus disease 2019 (COVID-19) pandemic has challenged and almost completely disrupted the previous teaching system, based mainly on teachers’ and learners’ physical presence. This impact has forced educators to identify alternative learning models and begin utilizing new approaches, often without detailed analysis or thorough, systematic planning. The current literature review aims to reveal some of the greatest pedagogical challenges in remotely teaching psychiatry residents during the pandemic. This minireview’s results may help in developing additional pedagogical techniques and key applications for educational activities to teach psychiatry residents, as well as to suggest directions for future psychiatry resident education. [ABSTRACT FROM AUTHOR]
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- 2022
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32. Prevalence of ADHD and Autism Spectrum Disorder in Children with Hypermobility Spectrum Disorders or Hypermobile Ehlers-Danlos Syndrome: A Retrospective Study.
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Kindgren, Erik, Perez, Antonia Quiñones, and Knez, Rajna
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CHILDREN with autism spectrum disorders ,EHLERS-Danlos syndrome ,SYMPTOMS ,AUTISM spectrum disorders ,DIAGNOSIS ,ELECTRONIC records - Abstract
Introduction: Hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS) are both characterized by generalized hypermobility, in combination with pain, affected proprioception, and pronounced fatigue. Clinical observation indicates that behavioral problems, hyperactivity, and autistic traits are overrepresented in children with those conditions. The purpose of this retrospective study was to establish the prevalence of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) among children with HSD and hEDS treated in our clinic since 2012. Subjects and Methods: Since Ehlers-Danlos syndrome (EDS) diagnostic criteria and international classification were changed in 2017, we equate the older diagnosis EDS hypermobility type with the newer hEDS and the older hypermobility syndrome with HSD. A registry search from the computerized medical record system found 201 children (88 boys, 113 girls) aged 6– 18 years who were treated at our pediatrics department with the diagnoses HSD or EDS. All medical records (113 with HSD, 88 with EDS) were reviewed, and key symptoms such as fatigue and pain, as well as diagnosis of ADHD/ASD, were recorded. Results: All EDS cases could be classified as hEDS. Of the entire study cohort, 16% had a verified ADHD diagnosis and a further 7% were undergoing ADHD diagnostic investigation. Significantly more children with hEDS had ADHD compared to children with HSD (p=0.02). In the age group 15– 16 years, 35% of those with hEDS had ADHD and, among those aged 17– 18 years, ADHD was present in 46%. Children with coexisting ADHD showed a significantly higher proportion of associated symptoms such as fatigue, sleep-problems, and urinary tract problems. ASD had been verified in 6% of the children. Of those with ASD, 92% had sleep problems. Conclusion: This study shows a strong association between HSD or hEDS and ADHD or ASD. Therefore, children with HSD or hEDS may need to be routinely screened for neuropsychiatric symptoms. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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33. Anksiozni i depresivni poremećaji u djece i adolescenata oboljelih od diabetes mellitus
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Đorić, Ana, Stevanović, Dejan, and Knez, Rajna
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anksiozni poremećaji ,depresivni poremećaji ,diabetes mellitus - Abstract
Diabetes mellitus (DM) and mental health problems are frequently co-occurring conditions. Anxiety and depressive disorders are the most common mental disorders that accompany DM. These conditions could have severe consequences in children and adolescents suffering from DM. Thus, it is important to pay additional attention to them. This article provides an overview of prevalence rates of DM and co- occurring anxiety and depression, as well as understandings in etiological characteristics and treatment options for anxiety and depressive disorders in children and adolescents with DM.
- Published
- 2018
34. ESSENCE-Q: Slavic language versions for developmental screening in young children
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Stevanovic, Dejan, Knez, Rajna, Zorcec, Tatjana, Anderluh, Marija, Kodrič, Jana, Petrov, Petar, Hadžagić Ćatibušić, Feriha, Deljković, Azra, Brkic Cvetkovic, Slavica, Vrljičak Davidovic, Nikolina, Kuzmanić Šamija, Radenka, Đorić, Ana, and Gillberg, Christopher
- Subjects
early screening ,Neuropsychiatric Disease and Treatment ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Psihijatrija ,intellectual disability ,questionnaire ,autism ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Psychiatry ,Original Research - Abstract
Dejan Stevanovic,1 Rajna Knez,2,3 Tatjana Zorcec,4 Marija Anderluh,5 Jana KodriÄ,5 Petar Petrov,6 Feriha HadžagiÄ ÄatibušiÄ,7 Azra DeljkoviÄ,8 Slavica Brkic Cvetkovic,1 Nikolina VrljiÄak Davidovic,9 Radenka KuzmaniÄ Šamija,10 Ana ÐoriÄ,11 Christopher Gillberg12 1Psychiatry Department, Clinic for Neurology and Psychiatry for Children and Youth, Belgrade, Serbia; 2Department of Child and Adolescent Psychiatry, Skaraborgs Hospital, Skövde, Sweden; 3Department of Psychiatry and Psychological Medicine, Faculty of Medicine, University of Rijeka, Rijeka, Croatia; 4Developmental Department, University Children’s Hospital, Skopje, Macedonia; 5Department of Child Psychiatry, University Children’s Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia; 6Department of Child and Adolescent Psychiatry, University Hospital St Marina, Varna, Bulgaria; 7Pediatric Clinic, Clinical Center Sarajevo, Bosnia and Herzegovina; 8Psychiatry Department, Mental Health Center Pljevlja, Pljevlja, Montenegro; 9Department of Child and Adolescent Psychiatry, Clinical Hospital Center, Split, Croatia; 10Clinic for Children’s Disorders, Clinical Hospital Center, Split, Croatia; 11Center of Applied Psychology, Faculty of Humanity and Social Sciences, University of Rijeka, Rijeka, Croatia; 12Gillberg Neuropsychiatry Center, University of Gothenburg, Gothenburg, Sweden Purpose: The Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations – Questionnaire (ESSENCE-Q) was developed as a brief screener to identify children with developmental concerns who might have neurodevelopmental disorders (NDDs). This study aimed to translate the ESSENCE-Q into south Slavic languages, namely, Bosnian, Bulgarian, Croatian, Macedonian, Montenegrin, Serbian, and Slovenian, and to evaluate its psychometric properties for screening purposes in clinical settings. Patients and methods: In the study, the ESSENCE-Q was completed for 251 “typically developing” children and 200 children with 1 or more diagnosed NDDs, all aged 1–6 years. Internal consistency and construct validity were tested first, followed by generating receiver operating characteristic curves and the area under the curve. Optimal cutoff values were then explored. Results: The Cronbach’s α coefficients were 0.91, 0.88, and 0.86 for ESSENCE-Q parent-completed form, and the telephone and direct interview forms administered by trained nurse or specialist, respectively. The 3 versions produced area under the curve values (95% confidence interval): 0.96 (0.93–0.99), 0.91 (0.86–0.95), and 0.91 (0.86–0.97), respectively. An optimal cutoff for ESSENCE-Q parent-completed form was found to be ≥3 points, while for the telephone and direct interviews, it was ≥5 points. Conclusion: We found adequate measurement properties of the south Slavic languages versions of the ESSENCE-Q as a screener for NDDs in clinical settings. This study provided additional data supporting sound psychometric properties of the ESSENCE-Q. Keywords: early screening, questionnaire, autism, intellectual disability
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- 2018
35. Screening for neurodevelopmental disorders in clinical settings with the ESSENCE-Q South Slavic language versions
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Stevanovic, Dejan, Anderluh, Marija, Kodric, Jana, Bokalic, Melita, Zorcec, Tatjana, Petrov, Petar, Hadzagic Catibusic, Feriha, Deljkovic, Azra, Vrljicak Davidovic, Nikolina, Kuzmanic Samija, Radenka, Doric, Ana, Knez, Rajna, and Gillberg, Christopher
- Subjects
Neurodevelopmental disorders, screening, children - Abstract
Objectives: To test the sensitivity and specificity of the parent form of the ESSENCE-Q South Slavic language versions as a screening instrument for neurodevelopmental disorders (NDDs) in clinical settings. Methods: Children under the age of 6 assessed for developmental problems from seven centers in Bosnia and Herzegovina, Bulgaria, Croatia, Macedonia, Montenegro, Serbia, and Slovenia were included. Forty eight children had one or more NDDs, while 86 were of normal development. One parent per child completed the ESSENCE-Q with 12 items (possible scores 0-24). Results: Cronbach’s alpha for the total score was 0.91. The area under the curve (AUC) was 0.96, where an optimal cut-off ≥ 3 had sensitivity of 0.96 (95% confidence interval [CI]: [0.86, 0.99]) and specificity of 0.84 (95% CI: [0.75, 0.91]). The diagnostic accuracy was similar when screening boys and girls separately (Youden index was 0.78 and 0.79, respectively), while it was greater when screening children aged 12-36 months than children aged 37-72 months (Youden index was 0.86 and 0.57, respectively). Conclusions: The ESSENCE-Q South Slavic language versions completed by parents could be used as a screening tool to identify children with NDDs in clinical settings. The screening instrument might have greater diagnostic accuracy when screening younger than older children, but this trend should be further confirmed.
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- 2018
36. Development and initial validation of the ESSENCE-Q South Slavic language versions
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Stevanović, Dejan, Knez, Rajna, Zorčec, Tatjana, Anderluh, Marija, Kodrič, Jana, Bokalič, Melita, Petrov, Petar, Hadžagić Ćatibušić, Feriha, Deljković, Azra, VrljiČak Davidović, Nikolina, Kuzmanić Samija, Radenka, Dorić, Ana, Wentz, Elisabet, and Gillberg, Christopher
- Subjects
Neurodevelopmental disorders ,screening ,children - Abstract
Objectives: To translate the ESSENCE-Q screening instrument for neurodevelopmental disorders into South Slavic languages, namely Bosnian, Bulgarian, Croatian, Macedonian, Montenegrin, Serbian, and Slovenian. Methods: The ESSENCE-Q (12 items, possible total scores 0-24) was translated into languages abovementioned in a multiple-step process. Afterwards, it was administered via interviews with one parent for a total of 112 children under the age of 6 assessed for developmental difficulties. Forty of the screened children had one or more neurodevelopmental disorders (NDDs). Results: The translated questionnaires have appropriate content and face validity, with sound conceptual, item, semantic, and operational equivalence with the original. Only two items were found to be incomprehensive (“Motor development/milestones” and “Funny spells/absences). Thus, slight modifications were applied, preserving the original meaning. On average, children with NDDs had significantly higher scores than healthy children or children with psychological symptoms not related to NDDs (F(df) = 38.27(2), p < 0.001). Based on receiver operating characteristics analysis, an optimal cut-off of ≥4 had 85% sensitivity and 72.2% specificity. Conclusions: The ESSENCE-Q versions developed in this study have promising measurement properties when screening for children with NDDs in countries speaking South Slavic languages.
- Published
- 2018
37. The Impact of Methylphenidate on QbTest Performance of Children with ADHD: A Retrospective Clinical Study.
- Author
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Knez, Rajna, Stevanovic, Dejan, Nasic, Salmir, Doric, Ana, and Wentz, Elisabet
- Subjects
- *
PERFORMANCE in children , *TEENAGE boys , *METHYLPHENIDATE , *MOTION capture (Human mechanics) , *ATTENTION-deficit hyperactivity disorder - Abstract
Introduction: The Quantified behavior Test (QbTest), which combines a continuous performance task (CPT) and motion tracking, provides data for the core signs of attention-deficit/hyperactivity disorder (ADHD): attention, hyperactivity, and impulsivity. This study aimed to evaluate the performance of children and adolescents with ADHD on the QbTest before and after a single methylphenidate (MPH) dose. Subjects and Methods: This retrospective chart review study included data from 149 children and 215 adolescents who completed the QbTest. A summary index of the CPT and motion capture data on the QbTest is provided by three cardinal parameters: QbActivity, QbImpulsivity, and QbInattention. The test was performed twice on the same day, before and up to three hours after MPH intake. A decrease by ≥ 0.5 in a cardinal parameter score was considered an improvement, whereas an increase by ≥ 0.5 a deterioration. Results: QbActivity improvement after MPH intake was present in 71.7% and 76.2% of the children and adolescents, respectively. QbImpulsivity improvement was observed in 50.4% of the children and 44.7% of the adolescents, and QbInattention improvement in 85.1% and 91.1% of the children and adolescents, respectively. All three parameters improved simultaneously in 27.7% of the children and 28.7% of the adolescents. The likelihood that one parameter deteriorated after MPH use was greater if that parameter was within the normal range before medication. This was most pronounced for QbImpulsivity. Among male adolescents, QbInattention improvement was often accompanied by QbImpulsivity deterioration. Conclusion: The QbTest inattention and motor activity parameters improved markedly after a single MPH dose in children and adolescents with ADHD, while less so for impulsivity. Improvement of one parameter is not necessarily associated with improvement of the other two, and deterioration, especially regarding impulsivity, may occur. If confirmed, these results highlight the need for optimization and individualization of MPH treatment, while monitoring all aspects of the ADHD symptomatology based on the QbTest performance. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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38. PERSONAL WELLBEING, WORK ABILITY, SATISFACTION WITH LIFE AND WORK IN PSYCHIATRISTS WHO EMIGRATED FROM CROATIA.
- Author
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Gruber, Ema, Sarajlic Vukovic, Iris, Musovic, Martina, Moravek, Davor, Starcevic, Branka, Martic-Biocina, Sanja, and Knez, Rajna
- Published
- 2020
39. Migration of Croatian physicians in the global context.
- Author
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Gruber, Ema, Vukovic, Iris Sarajlic, Musovic, Martina, Moravek, Davor, Starcevic, Branka, Biocina, Sanja Martic, and Knez, Rajna
- Subjects
EMIGRATION & immigration ,PHYSICIANS - Abstract
Copyright of Medicina Fluminensis is the property of Croatian Medical Association, Rijeka Branch & Faculty of Medicine, University of Rijeka and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
40. UCLA PTSD reaction index for DSM-5 (PTSD-RI-5): a psychometric study of adolescents sampled from communities in eleven countries.
- Author
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Doric, Ana, Stevanovic, Dejan, Stupar, Dusko, Vostanis, Panos, Atilola, Olayinka, Moreira, Paulo, Dodig-Curkovic, Katarina, Franic, Tomislav, Davidovic, Vrljicak, Avicenna, Mohamad, Noor, Multazam, Nussbaum, Laura, Thabet, Abdelaziz, Ubalde, Dino, Petrov, Petar, Deljkovic, Azra, Antonio, Monteiro Luis, Ribas, Adriana, Oliveira, Joana, and Knez, Rajna
- Abstract
Copyright of European Journal of Psychotraumatology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
41. The translation and cultural adaptation of the ESSENCE-Q: Experience from south Slavic languages.
- Author
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Stevanović, Dejan and Knez, Rajna
- Subjects
- *
TRANSLATIONS , *CULTURAL adaptation , *QUESTIONNAIRES - Published
- 2018
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42. Anxiety and depressive disorders in children and adolescents suffering from diabetes mellitus.
- Author
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Đorić, Ana, Stevanović, Dejan, and Knez, Rajna
- Subjects
DIABETES risk factors ,DEPRESSION in adolescence ,ANXIETY in children - Abstract
Copyright of Medicina Fluminensis is the property of Croatian Medical Association, Rijeka Branch & Faculty of Medicine, University of Rijeka and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
- Full Text
- View/download PDF
43. Can we really use available scales for child and adolescent psychopathology across cultures? A systematic review of cross-cultural measurement invariance data.
- Author
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Stevanovic, Dejan, Jafari, Peyman, Knez, Rajna, Franic, Tomislav, Atilola, Olayinka, Davidovic, Nikolina, Bagheri, Zahra, and Lakic, Aneta
- Subjects
ADOLESCENT psychology ,CHILD psychology ,PSYCHOLOGY information storage & retrieval systems ,MEDLINE ,PATHOLOGICAL psychology ,QUESTIONNAIRES ,SYSTEMATIC reviews ,ADOLESCENCE ,CHILDREN - Abstract
In this systematic review, we assessed available evidence for cross-cultural measurement invariance of assessment scales for child and adolescent psychopathology as an indicator of cross-cultural validity. A literature search was conducted using the Medline, PsychInfo, Scopus, Web of Science, and Google Scholar databases. Cross-cultural measurement invariance data was available for 26 scales. Based on the aggregation of the evidence from the studies under review, none of the evaluated scales have strong evidence for cross-cultural validity and suitability for cross-cultural comparison. A few of the studies showed a moderate level of measurement invariance for some scales (such as the Fear Survey Schedule for Children-Revised, Multidimensional Anxiety Scale for Children, Revised Child Anxiety and Depression Scale, Revised Children's Manifest Anxiety Scale, Mood and Feelings Questionnaire, and Disruptive Behavior Rating Scale), which may make them suitable in cross-cultural comparative studies. The remainder of the scales either showed weak or outright lack of measurement invariance. This review showed only limited testing for measurement invariance across cultural groups of scales for pediatric psychopathology, with evidence of cross-cultural validity for only a few scales. This study also revealed a need to improve practices of statistical analysis reporting in testing measurement invariance. Implications for future research are discussed. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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44. Cross-Cultural Measurement Invariance of Adolescent Self-Report on the Pediatric Quality of Life Inventory™ 4.0.
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Stevanovic, Dejan, Atilola, Olayinka, Vostanis, Panos, Pal Singh Balhara, Yatan, Avicenna, Mohamad, Kandemir, Hasan, Knez, Rajna, Franic, Tomislav, Petrov, Petar, Maroco, João, Terzic Supic, Zorica, and Bagheri, Zahra
- Subjects
ADOLESCENT analysis ,CROSS-cultural studies ,QUALITY of life ,DEMOGRAPHIC characteristics ,DIFFERENTIAL item functioning (Research bias) - Abstract
This study evaluated the cross-cultural measurement invariance of the Pediatric Quality of Life Inventory version 4.0 (Peds QL
™ ) among adolescents sampled from Bulgaria, Croatia, India, Indonesia, Nigeria, Serbia, and Turkey. The multiple-indicator multiple-cause ( MIMIC) model was used, which allowed controlling of demographic variables (i.e., age, gender, and socioeconomic status). Significant effects of country on scores within the Peds QL™ domains were observed, with up to 17 items showing differential item functioning ( DIF) across the countries. We did not find support for cross-cultural measurement invariance hypotheses for scores on the Peds QL™ adolescent self-report in this study. Researchers should use caution in making cross-cultural quality of life comparisons while using the Peds QL. [ABSTRACT FROM AUTHOR]- Published
- 2016
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45. The Relationships Between Alcohol/Drug Use and Quality of Life Among Adolescents: An International, Cross-Sectional Study.
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Stevanovic, Dejan, Atilola, Olayinka, Balhara, Yatan Pal Singh, Avicenna, Mohamad, Kandemir, Hasan, Vostanis, Panos, Knez, Rajna, and Petrov, Petar
- Subjects
QUALITY of life ,ETHANOL ,PSYCHOLOGY of high school students ,PROBABILITY theory ,QUESTIONNAIRES ,SELF-evaluation ,SUBSTANCE abuse ,SURVEYS ,T-test (Statistics) ,CROSS-sectional method ,DESCRIPTIVE statistics ,ADOLESCENCE - Abstract
Although a major public health and social concern globally, limited data exist on substance use and their effects among adolescents living in low- and middle-income countries. This study evaluated the relationships between alcohol/drug use and quality of life (QOL) among adolescents in general populations from India, Indonesia, Nigeria, Serbia, Turkey, Bulgaria, and Croatia. The sample included 2,393 adolescents. The Pediatric Quality of Life Inventory (PedsQL) was used for QOL assessments, the Strengths and Difficulties Questionnaire (SDQ) was used for mental health problems, and the CRAFFT self-report questionnaire was administered for eliciting alcohol/drug use. Alcohol/drug use was significantly associated with lower levels of QOL. In particular, substance use among older male adolescents, adolescents with overt psychopathology, or adolescents in lower socioeconomic status was associated with greater reductions in levels of QOL. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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46. Less is More - Possible Option in the Treatment of Depression.
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Dadić-Hero, Elizabeta, Knez, Rajna, and Rebić, Jelena
- Subjects
MENTAL depression ,THERAPEUTICS ,MODERN society ,AGE factors in disease ,ETIOLOGY of diseases ,FRUSTRATION ,PSYCHIATRISTS - Abstract
Copyright of Collegium Antropologicum is the property of Croatian Anthropological Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2014
47. Healthcare professionals' perceptions of a digital parental support, Childbirth Journey , constructed as a serious game-An intervention study.
- Author
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Bäckström C, Knez R, and Larsson M
- Abstract
Background: Globally, the digital sources developed and available in antenatal care differ, and infrastructure challenges may impede the further development of such sources. Challenges accompanying digital developments can include the commonly occurring high workload, which affects healthcare professionals' ability to acquire professional knowledge about how to best support parents in using digital sources. Including healthcare professionals in the development process of digital sources may increase the likelihood that such sources will be adopted and employed by these professionals in their future care work. Therefore, the present research explored healthcare professionals' perceptions of the digital support intervention Childbirth Journey, which was constructed as a serious game for expectant parents., Methods: Data were collected through semi-structured focus-group interviews with 11 midwives at antenatal, labour and postnatal clinics as well as with child healthcare nurses. Prior to the interviews, all participants were provided the intervention, Childbirth Journey, which is a serious game in a mobile application format consisting of two distinct parts: (1) a story-driven game and (2) a Knowledge Portal . The data were analysed using phenomenographic methods., Results: The perceptions of Childbirth Journey by healthcare professionals, midwives and child healthcare nurses are presented in four descriptive categories: extended professional support, trustworthy contents, diversity or individuality, and both appealing and in need of development., Conclusions: Current study revealed that Childbirth Journey may be utilised as a digital support for parents, allowing healthcare professionals to offer a digital solution as a complementary support to standard, face-to-face meetings with caregivers. However, the research results also revealed that some elements of Childbirth Journey must be improved, thereby representing a main contribution of this study: insights into how to better develop digital tools under the umbrella of health care. Thus, we conclude that in order to create sustainable and safe digital care solutions that function as trustworthy professional supports instead of technical products that risk harming users, the perspectives of both patients and healthcare professionals should be considered in the exploration and development of these solutions., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2023 Bäckström, Knez, Larsson.)
- Published
- 2023
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48. Orexin/hypocretin system dysfunction in patients with Takotsubo syndrome: A novel pathophysiological explanation.
- Author
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Knez R, Niksic M, and Omerovic E
- Abstract
Takotsubo syndrome (TTS) is an acute heart failure syndrome. Emotional or physical stressors are believed to precipitate TTS, while the pathophysiological mechanism is not yet completely understood. During the coronavirus disease (COVID-19) pandemic, an increased incidence of TTS has been reported in some countries; however, the precise pathophysiological mechanism for developing TTS with acute COVID-19 infection is unknown. Nevertheless, observing the symptoms of COVID-19 might lead to new perspectives in understanding TTS pathophysiology, as some of the symptoms of the COVID-19 infection could be assessed in the context of an orexin/hypocretin-system dysfunction. Orexin/hypocretin is a cardiorespiratory neuromodulator that acts on two orexin receptors widely distributed in the brain and peripheral tissues. In COVID-19 patients, autoantibodies against one of these orexin receptors have been reported. Orexin-system dysfunction affects a variety of systems in an organism. Here, we review the influence of orexin-system dysfunction on the cardiovascular system to propose its connection with TTS. We propose that orexin-system dysfunction is a potential novel explanation for the pathophysiology of TTS due to direct or indirect dynamics of orexin signaling, which could influence cardiac contractility. This is in line with the conceptualization of TTS as a cardiovascular syndrome rather than merely a cardiac abnormality or cardiomyopathy. To the best of our knowledge, this is the first publication to present a plausible connection between TTS and orexin-system dysfunction. We hope that this novel hypothesis will inspire comprehensive studies regarding orexin's role in TTS pathophysiology. Furthermore, confirmation of this plausible pathophysiological mechanism could contribute to the development of orexin-based therapeutics in the treatment and prevention of TTS., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Knez, Niksic and Omerovic.)
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- 2022
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49. Measurement invariance of the Childhood Autism Rating Scale (CARS) across six countries.
- Author
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Stevanovic D, Costanzo F, Fucà E, Valeri G, Vicari S, Robins DL, Samms-Vaughan M, Ozek Erkuran H, Yaylaci F, Deshpande SN, Deshmukh V, Arora NK, Albores-Gallo L, García-López C, Gatica-Bahamonde G, Gabunia M, Zirakashvili M, Machado FP, Radan M, Samadi SA, Toh TH, Gayle W, Brennan L, Zorcec T, Auza A, de Jonge M, Shoqirat N, Marini A, and Knez R
- Subjects
- Bayes Theorem, Child, Cross-Cultural Comparison, Humans, Psychometrics, United States, Autism Spectrum Disorder diagnosis, Autistic Disorder
- Abstract
The Childhood Autism Rating Scale (CARS) is a simple and inexpensive tool for Autism spectrum disorder (ASD) assessments, with evidenced psychometric data from different countries. However, it is still unclear whether ASD symptoms are measured the same way across different societies and world regions with this tool, since data on its cross-cultural validity are lacking. This study evaluated the cross-cultural measurement invariance of the CARS among children with ASD from six countries, for whom data were aggregated from previous studies in India (n = 101), Jamaica (n = 139), Mexico (n = 72), Spain (n = 99), Turkey (n = 150), and the United States of America (n = 186). We analyzed the approximate measurement invariance based on Bayesian structural equation modeling. The model did not fit the data and its measurement invariance did not hold, with all items found non-invariant across the countries. Items related to social communication and interaction (i.e., relating to people, imitation, emotional response, and verbal and nonverbal communication) displayed lower levels of cross-country non-invariance compared to items about stereotyped behaviors/sensory sensitivity (i.e., body and object use, adaptation to change, or taste, smell, and touch response). This study found that the CARS may not provide cross-culturally valid ASD assessments. Thus, cross-cultural comparisons with the CARS should consider first which items operate differently across samples of interest, since its cross-cultural measurement non-invariance could be a source of cross-cultural variability in ASD presentations. Additional studies are needed before drawing valid recommendations in relation to the cultural sensitivity of particular items., (© 2021 International Society for Autism Research and Wiley Periodicals LLC.)
- Published
- 2021
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50. Digital Tools as Parental Support-A Study Protocol Describing Prospective Development and Exploration of Two Digital Tools for Parents.
- Author
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Bäckström C, Engström H, Knez R, and Larsson M
- Abstract
Background: The access to digital tools for parents is increasing, and further exploration is needed to gain knowledge about parents' experiences in using such tools, for example, when preparing for childbirth and parenthood. This study protocol describes a prospective study that will explore serious games as digital tools for parental support, and both parents' and healthcare professionals' views will be included. The objectives of the prospective study are to explore two different serious games: (1) Childbirth Journey (Swedish: Förlossningsresan), relating to pregnancy, childbirth and parenthood; and (2) Interplay (Swedish: Samspel), relating to parental couple relationships and parenthood. Methods: An intervention study will be conducted. The study will include four different sub-studies (A-D) with both qualitative and quantitative methods and a longitudinal design. Both parents (A, B and D) and healthcare professionals (C) will be included, and data will be collected through interviews (A-C) and repeated web-based questionnaires (D). Data will be analysed using phenomenography and qualitative content analysis (A-C), and descriptive and analytical analyses will be performed for comparisons and associations (D). Discussion: The value of monitoring and reporting on developments and trends in digital innovation for public health has been stipulated by the World Health Organization. The prospective study will contribute further knowledge about multidisciplinary development of digital tools as professional support for parents, as well as knowledge about parents' and healthcare professionals' experiences using digital tools concerning pregnancy, labour, parenthood and parental couple relationships. Trial Registration: This study was retrospectively registered (02/10/2020) within the ISRCTN with ID: ISRCTN18017741. http://www.isrctn.com/ISRCTN18017741., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Bäckström, Engström, Knez and Larsson.)
- Published
- 2021
- Full Text
- View/download PDF
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