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When impinging on the lithosphere in spreading ridges or intra-plate settings, the asthenospheric mantle can significantly influence plate tectonics. However, the active role of the asthenospheric mantle on subducting slabs remains poorly understood. The main reason for this dispute is the lack of typical geochemical mafic rocks in the subduction zone. In this paper, we first report the Early Jurassic (187 Ma) Yurongguo Nb-enriched basalts in the western segment of the Bangong-Nujiang suture zone. These samples show typical Nb-enriched basaltic features with high Na 2 O, TiO 2 , Nb (>7 ppm), high Nb/Th (average = 11.05), Nb/La (average = 1.37) and Nb/U (average = 72.98) ratios. Unlike the adakite-related Nb-enriched basalts, the Yurongguo Nb-enriched basalts formed from the mixture of magmas derived from upwelling asthenosphere (20–30%) and depleted mantle (70–80%) in the spinel lherzolite region (<70 km). We conclude the Yurongguo Nb-enriched basalts were formed in the fore-arc basin setting with the influence of slab rollback, which occurred under the intra-oceanic subduction. Two southward intra-oceanic subductions may exist in the western part of the Bangong-Nujiang Tethyan Ocean in the Jurassic. The Early Jurassic (200–180 Ma) intra-oceanic subduction formed the fore-arc basin, probably accompanied by asthenospheric mantle activity at the same time, followed closely by flat subduction due to the oceanic plateau. After a period of geological stabilization, the Late Jurassic (170–150 Ma) was the period when the spreading of the little ocean basin ceased, and the second intra-oceanic subduction occurred. We proposed an oceanic plateau-subducted oceanic slab interaction and overriding intra-oceanic subduction model for the Meso-Tethyan subduction in the western Tibetan Plateau. • Yurongguo rocks were formed in 187 Ma, which are the typical Nb-enriched basalts. • OIB (20–30%) and MORB (70–80%) mixed to form the Yurongguo Nb-enriched basalts. • Yurongguo Nb-enriched basalts are the consequence of intra-oceanic subduction. • Oceanic plateau played an important role in the intra-oceanic subduction. [ABSTRACT FROM AUTHOR]