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Ticks are blood-sucking parasites and occur all over the world, especially in humid and subhumid nations such as India. They are very important vectors of many economically important livestock diseases, such as Anaplasma spp., Babesia spp., and Theileria spp. Ticks were collected from organized and unorganized cattle farms situated in and around Mhow. The initially collected samples of ticks (≤200) were washed in tap water and identified as Rhipicephalus microplus. The study was carried out from June 2021 to May 2022. Ticks were treated with 0.625, 1.25, 2.50, 5, and 10% oil of Azadirachta indica in both the adult immersion test and larval immersion test. All the concentrations were prepared with absolute ethanol. In the present study, fipronil was used as a positive control using various concentrations (x/8, x/4, x/2, x, and 2x) and was prepared in distilled water. The LC50 values against fipronil were observed as 1.03 and 1.12 ppm for adults and larvae, respectively. Results of the study showed that the oil of Azadirachta indica was responsible for the mortality of adults (LC50 = 2.70%) and larval stages (LC50 = 1.27%) at all the concentrations used. Furthermore, it was observed that this oil was also responsible for the inhibition of oviposition and had excellent repellent activity at 10% concentration. Based on the study, we can conclude that the oil of A. indica can be used in an integrated tick management system to reduce the tick burden on animals. [ABSTRACT FROM AUTHOR]

Advanced oxidation processes (AOPs) in water treatment industries can simultaneously offer disinfection and eradicate organic contaminants. The present work examined the direct exposure impact of various oxidative (UV, O3, and H2O2) and their eclectic combinations (UV/O3, H2O2/O3, and UV/H2O2) for the abolition of Trihalomethane (THMs) precursors. The application of the Fenton process proved to be the most effective technique for reducing TOC (85.23%) and UV254 (91.11%) than other used AOPs. Higher removal of THMs precursors found in the Fenton process may be attributed to the higher degradation potential of hydroxyl radical generated from this process than other AOPs. The deformed ferrous iron salts (Fe2+) in the Fenton reagent catalyzed the hydrogen peroxide (H2O2) and produced highly reactive radicals. Seasonal probabilistic lifetime cancer and non-cancer risks of THMs in males and females were also investigated in the drinking water supplies of five major cities in India. Comparative risk analysis through different pathways revealed significant risk from oral ingestion (99%), followed by inhalation exposure (0.77%) and dermal absorption (0.002%), where females were found at higher risk of cancer. Sensitivity analysis using a radar plot was also performed to identify the most influential parameter affecting the total risk of cancer. The Risk value of chloroform (CF) was highest among the THMs compound in all the WTPs for both seasons. Seasonal risk assessment revealed a higher risk of cancer in the pre-monsoon season. [ABSTRACT FROM AUTHOR]