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Renicoris gen. nov. and its type species Renicoris robustus sp. nov. (Hemiptera: Heteroptera: Reduviidae: Harpactorinae) from Yunnan, China, are described and illustrated. A key to separate the new genus and its closely related genera is provided. [ABSTRACT FROM AUTHOR]

Two new species of the thread-legged bug genus Ademula McAtee & Malloch, 1926 (Hemiptera: Reduviidae: Emesinae: Emesini, formerly Ploiariolini) from China, A. callipennis, new species, and A. corniculata, new species, are described and illustrated in the present paper. COI barcodes of these two new species and an updated key to the Oriental species of Ademula are provided. The distribution of Ademula in East and Southeast Asia is briefly discussed. [ABSTRACT FROM AUTHOR]

The goal of carbon neutrality provides a new opportunity for the development of renewable energy, especially for wind power. In this paper, 11 regional climate models (RCMs) including CORDEX-EA and PRECIS at two different resolutions are used to evaluate the performance in simulating the spatio-temporal characteristics for wind speed and energy potential from 1981 to 2005. The results show that most models can reproduce the spatio-temporal patterns, and the simulation of the eastern region is better than that of the western region. Besides, most of the higher-resolution models had better simulation performance for spatial-temporal patterns and inter-annual variation. Then, the weighted multi-model ensemble is used to project the changes of the wind speed and the wind power density over China's mainland during the mid-21st century under the RCP8.5 scenario. In future, a decrease in wind speed is projected by most RCMs over China, although some regions, such as the southern parts of China, are projected to have more wind energy potential. The percentage variation of annual mean wind speed will remain in the range of ±4%. The wind power density will decrease in the north and the largest decrease will be found in the northwest. However, the annual mean wind power density in the southeast China will have an increase of 2.21% in the middle of this century. The inter-annual variation of the wind power density in most regions will increase by more than 20%. However, intra-annual variation in the wind power density is likely to decrease in most regions of China, ranging from about −20% to −50%. • A weighted multi-model ensemble was used to project the changes of wind power density over China. • The changes of annual mean wind power density vary in different sub-regions of China, ranging from −3.21% to 2.21%. • The inter-annual variation of the WPD in most regions will increase by more than 20%. [ABSTRACT FROM AUTHOR]

Background: To explore the short‐ and long‐term outcomes in patients with nasopharyngeal carcinoma (NPC) with magnetic resonance imaging (MRI)‐detected residual disease at 3 months post‐treatment who received intervention either promptly (0 month) or following observation (after an additional 3 months). Methods: A total of 272 patients with residual disease at 3 months post‐treatment (observation [observation for additional 3 months]: 122, intervention [prompt intervention]: 150) were analyzed. Univariate and multivariate analyses were performed to examine the survival. Adverse events were analyzed in all patients. Results: Patients in the observation group had a lower 3‐year overall survival (77.1% vs. 85.2%), progression‐free survival (10.2% vs. 18.1%), and locoregional relapse‐free survival (10.2% vs. 20.6%) (all p <.05), but not distant metastasis‐free survival (83.8% vs. 78.4%, p =.189), whereas patients in the intervention group achieved higher complete remission (CR) rates (43.3% vs. 21.2%, p =.003). Patients who achieved CR after prompt intervention had a better survival rate than those who achieved observation‐CR or non‐CR (p <.001). Multivariate analyses revealed that a wait‐and‐see policy was an independent prognostic factor for impaired survival (p <.001). No significant differences of acute or late toxicities were observed between the two groups. Conclusions: Patients with NPC with MRI‐detected residual disease 3 months post‐radiotherapy should be encouraged to undergo prompt intervention rather than adopting a passive wait‐and‐see policy. [ABSTRACT FROM AUTHOR]

Because effective control measures are lacking, tea leaf spot caused by Didymella segeticola results in huge tea (Camellia sinensis) production losses on tea plantations in Guizhou Province, southwestern China. Screening for natural antimicrobial agents with higher control effects against this pathogen and studying their modes of action may contribute to disease management. Here, Penicillium griseofulvum-derived antimicrobial griseofulvin (GSF) can inhibit the hyphal growth of D. segeticola strain GZSQ-4, with a half-maximal effective concentration of 0.37 μg/ml in vitro and a higher curative efficacy at a lower dose of 25 μg/ml for detached tea twigs. GSF induces deformed and slightly curly hyphae with enlarged ends, with protoplasts agglutinated in the hyphae, and higher numbers of hyphal protuberances. GSF alters hyphal morphology and the subcellular structure's order. The integrated transcriptome and proteome data revealed that the transport of materials in cells, cellular movement, and mitosis were modulated by GSF. Molecular docking indicated that beta-tubulin was the most potent target of GSF, with a binding free energy of −13.59 kcal/mol, and microscale thermophoresis indicated that the dissociation constant (Kd) value of GSF binding to beta-tubulin 1, compared with beta-tubulin 2, was significantly lower. Thus, GSF potentially targets beta-tubulin 1 to disturb the chromosomal separation and fungal mitosis, thereby inhibiting hyphal growth. [ABSTRACT FROM AUTHOR]

Few studies have evaluated the long-term relationship between diet quality and cardiometabolic risk factor clustering among children. The moderating effect of socio-economic status (SES) is of interest. To investigate the association between diet quality with cardiometabolic risk among Chinese children and to explore the moderating effect of SES. In this cohort study, 5 waves (1997-2009) of the China Health and Nutrition Survey were used. Diet quality was measured by a modified version of the Chinese Children Dietary Index (mCCDI) based on Dietary Guidelines for Chinese. Children between the ages of 7 and 17 (n = 2903) who completed at least 2 surveys were included. Those who missed measures or had hypertension or diabetes at baseline were excluded. The fasting blood samples were collected in 2009. Waist circumference (WC) and blood pressure (BP) were measured in each survey. A continuous cardiometabolic risk score (MetScore) was derived by a confirmatory factor analysis of 5 components: WC, BP, glucose, triglycerides, and high-density lipoprotein cholesterol. Considering the latency period of the effect of behaviors, the mCCDI was lagged by the period between surveys. Linear regression was used to analyze the association of mCCDI with MetScore and its components. Mixed effect linear regression and lagged mCCDI were used for WC and BP models. Higher mCCDI was independently associated with a lower MetScore at follow-up (β: −.11; 95% CI: −.18 to −.04). Higher lagged mCCDI over time was associated with a lower WC z score overall (β: −.05; 95% CI: −.08 to −.01) and among children in the low SES group (β: −.09; 95% CI: −.14 to −.04) but not those in the high SES group. When examining the 15 mCDDI components separately, scores for 5 components: more grains, vegetables, soybeans and its products; less sugar-sweetened beverages; and more diet variety were significantly associated with a lower MetScore. Among Chinese children, higher diet quality measured by mCCDI was independently associated with a lower MetScore at follow-up. [ABSTRACT FROM AUTHOR]