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Your search keyword '"Gheorghe, Cristian"' showing total 11 results
11 results on '"Gheorghe, Cristian"'

1. Romanian Guidelines for the Diagnosis and Treatment of GERD-induced Respiratory Manifestations.

Author

Drug VL, Antoniu S, Oana BB, Arghir OC, Bancila I, Bataga S, Brisc C, Cijevschi-Prelipcean C, Ciocîrlan M, Ciortescu I, David L, Deleanu OC, Diculescu M, Dimitriu A, Dobru D, Dumitru E, Gheonea DI, Gheorghe C, Goldis A, Jinga M, Man M, Mateescu B, Manuc M, Mihai C, Mihaltan F, Mihaescu T, Nedelcu L, Negreanu L, Pop CM, Rajnoveanu R, Saftoiu A, Seicean A, Sporea I, Stanciu C, Surdea-Blaga T, Tantau M, Todea D, Trifan AV, Ulmeanu R, Iov DE, and Dumitrascu DL

Subjects
Cough complications, Cough drug therapy, Humans, Proton Pump Inhibitors therapeutic use, Romania epidemiology, Gastroenterology, Gastroesophageal Reflux complications, Gastroesophageal Reflux diagnosis, Gastroesophageal Reflux therapy
Abstract

Background and Aims: Gastroesophageal reflux disease (GERD) is a common condition present in daily practice with a wide range of clinical phenotypes. In this line, respiratory conditions may be associated with GERD. The Romanian Societies of Gastroenterology and Neurogastroenterology, in association with the Romanian Society of Pneumology, aimed to create a guideline regarding the epidemiology, diagnosis and treatment of respiratory conditions associated with GERD., Methods: Delphi methodology was used and eleven common working groups of experts were created. The experts reviewed the literature according to GRADE criteria and formulated 34 statements and recommendations. Consensus (>80% agreement) was reached for some of the statements after all participants voted., Results: All the statements and the literature review are presented in the paper, together with their correspondent grade of evidence and the voting results. Based on >80% voting agreement, a number of 22 recommendations were postulated regarding the diagnosis and treatment of GERD-induced respiratory symptoms. The experts considered that GERD may cause bronchial asthma and chronic cough in an important number of patients through micro-aspiration and vagal-mediated tracheobronchial reflex. GERD should be suspected in patients with asthma with suboptimal controlled or after exclusion of other causes, also in nocturnal refractory cough which needs gastroenterological investigations to confirm the diagnosis. Therapeutic test with double dose proton pump inhibitors (PPI) for 3 months is also useful. GERD induced respiratory conditions are difficult to treat; however,proton pump inhibitors and laparoscopic Nissen fundoplication are endorsed for therapy., Conclusions: This guideline could be useful for the multidisciplinary management of GERD with respiratory symptoms in current practice.

Published
2022
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3. Clinical Insights for Gastroenterology and Hepatology Providers during the COVID-19 Pandemic.

Author

Gheorghe C

Subjects
COVID-19, Global Health, Humans, SARS-CoV-2, Betacoronavirus isolation & purification, Coronavirus Infections complications, Coronavirus Infections diagnosis, Coronavirus Infections epidemiology, Coronavirus Infections therapy, Gastroenterology, Pandemics, Pneumonia, Viral complications, Pneumonia, Viral diagnosis, Pneumonia, Viral epidemiology, Pneumonia, Viral therapy
Published
2020
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4. Diagnosis and Treatment of Colonic Diverticular Disease: Position Paper of the Romanian Society of Gastroenterology and Hepatology.

Author

Trifan A, Gheorghe C, Marica Sabo C, Diculescu M, Nedelcu L, Singeap AM, Sfarti C, Gheorghe L, Sporea I, Tanțău M, Scripcariu V, Goldiș A, Gheonea D, Manuc M, Stanciu C, Scarpignato C, and Dumitrascu DD

Subjects
Consensus, Diverticulitis, Colonic epidemiology, Diverticulosis, Colonic epidemiology, Diverticulum, Colon epidemiology, Evidence-Based Medicine standards, Humans, Predictive Value of Tests, Prevalence, Treatment Outcome, Diverticulitis, Colonic diagnosis, Diverticulitis, Colonic therapy, Diverticulosis, Colonic diagnosis, Diverticulosis, Colonic therapy, Diverticulum, Colon diagnosis, Diverticulum, Colon therapy, Gastroenterology standards
Abstract

Background and Aims: Diverticular disease of the colon is a common clinical condition in developed countries, and is associated with significant (direct and indirect) economic burden. The aim of this Position Paper is to provide clinical guidance for appropriate definition, prevalence, risk factors, diagnosis, and treatment of colonic diverticular disease., Methods: A working group of recognized experts established by the Board of the Romanian Society of Gastroenterology and Hepatology (RSGH) screened the literature and the available guidelines on colonic diverticular disease. Statements were formulated based on literature evidence. These statements were discussed within the working group and decision for each of them was taken by consensus., Results: Thirty two statements were elaborated. The grade of recommendation, according to the level of evidence was established for each statement. Short comments with literature support accompany each statement., Conclusion: This Position Paper represents a practical guide for clinicians dealing with patients affected by colonic diverticular disease.

Published
2018
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5. The use of mebeverine in irritable bowel syndrome. A Position paper of the Romanian Society of Neurogastroenterology based on evidence.

Author

Dumitrascu DL, Chira A, Bataga S, Diculescu M, Drug V, Gheorghe C, Goldis A, Nedelcu L, Porr PJ, and Sporea I

Subjects
Drug Therapy, Combination, Evidence-Based Medicine standards, Gastrointestinal Agents adverse effects, Humans, Irritable Bowel Syndrome diagnosis, Irritable Bowel Syndrome physiopathology, Irritable Bowel Syndrome psychology, Phenethylamines adverse effects, Quality of Life, Treatment Outcome, Gastroenterology standards, Gastrointestinal Agents therapeutic use, Irritable Bowel Syndrome drug therapy, Phenethylamines therapeutic use
Published
2014
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6. Excellence centers in inflammatory bowel disease in Romania: a measure of the quality of care.

Author

Negreanu L, Bataga S, Cijevschi Prelipcean C, Dobru D, Diculescu M, Dumitru E, Gheonea DI, Gheorghe L, Gheorghe C, Goldis A, Mateescu BR, Tantau M, and Trifan A

Subjects
Delivery of Health Care, Integrated standards, Guideline Adherence standards, Healthcare Disparities, Humans, Inflammatory Bowel Diseases diagnosis, Practice Patterns, Physicians' standards, Romania, Treatment Outcome, Gastroenterology standards, Inflammatory Bowel Diseases therapy, Outcome and Process Assessment, Health Care standards, Quality Improvement standards, Quality Indicators, Health Care standards
Published
2014
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8. Functional bowel disorders with diarrhoea: Clinical guidelines of the United European Gastroenterology and European Society for Neurogastroenterology and Motility

Author

Edoardo Savarino, Fabiana Zingone, Brigida Barberio, Giovanni Marasco, Filiz Akyuz, Hale Akpinar, Oana Barboi, Giorgia Bodini, Serhat Bor, Giuseppe Chiarioni, Gheorghe Cristian, Maura Corsetti, Antonio Di Sabatino, Anca Mirela Dimitriu, Vasile Drug, Dan L. Dumitrascu, Alexander C. Ford, Goran Hauser, Radislav Nakov, Nisha Patel, Daniel Pohl, Cătălin Sfarti, Jordi Serra, Magnus Simrén, Alina Suciu, Jan Tack, Murat Toruner, Julian Walters, Cesare Cremon, and Giovanni Barbara

Subjects
Diarrhea, FDr, IBS-D, abdominal pain, clinical practice guidelines, diarrhea, functional bowel disorders, functional diarrhea, irritable bowel syndrome, Bile Acids and Salts, Gastrointestinal Agents, Humans, Gastroenterology, Irritable Bowel Syndrome, INTESTINAL BACTERIAL OVERGROWTH, GASTROINTESTINAL DISORDERS, BILE-ACID MALABSORPTION, DOUBLE-BLIND, FECAL INCONTINENCE, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine, GLUTEN-FREE DIET, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina, Science & Technology, Gastroenterology & Hepatology, LACTOSE-MALABSORPTION, CELIAC-DISEASE, Oncology, CAPSULE ENDOSCOPY, ROME III, Life Sciences & Biomedicine
Abstract

Irritable bowel syndrome with diarrhoea (IBS-D) and functional diarrhoea (FDr) are the two major functional bowel disorders characterized by diarrhoea. In spite of their high prevalence, IBS-D and FDr are associated with major uncertainties, especially regarding their optimal diagnostic work-up and management. A Delphi consensus was performed with experts from 10 European countries who conducted a literature summary and voting process on 31 statements. Quality of evidence was evaluated using the grading of recommendations, assessment, development, and evaluation criteria. Consensus (defined as >80% agreement) was reached for all the statements. The panel agreed with the potential overlapping of IBS-D and FDr. In terms of diagnosis, the consensus supports a symptom-based approach also with the exclusion of alarm symptoms, recommending the evaluation of full blood count, C-reactive protein, serology for coeliac disease, and faecal calprotectin, and consideration of diagnosing bile acid diarrhoea. Colonoscopy with random biopsies in both the right and left colon is recommended in patients older than 50 years and in presence of alarm features. Regarding treatment, a strong consensus was achieved for the use of a diet low fermentable oligo-, di-, monosaccharides and polyols, gut-directed psychological therapies, rifaximin, loperamide, and eluxadoline. A weak or conditional recommendation was achieved for antispasmodics, probiotics, tryciclic antidepressants, bile acid sequestrants, 5-hydroxytryptamine-3 antagonists (i.e. alosetron, ondansetron, or ramosetron). A multinational group of European experts summarized the current state of consensus on the definition, diagnosis, and management of IBS-D and FDr. ispartof: UNITED EUROPEAN GASTROENTEROLOGY JOURNAL vol:10 issue:6 pages:556-584 ispartof: location:England status: published

Published
2022

10. Acid suppression therapy, gastrointestinal bleeding and infection in acute pancreatitis - An international cohort study

Author

Péter Jenő Hegyi, Áron Vincze, Alexandra Demcsák, László Gajdán, Andrey Litvin, Andra Iulia Suceveanu, Eva Pijoan Comas, Riccardo Casadei, George I Papachristou, Vincenzo Cennamo, Yu-Ting Chang, Péter Hegyi, Ionut Negoi, Carlo Ingaldi, Vitor Nunes, Adriano Quiroga Castiñeira, Lihui Deng, Orestis Ioannidis, Ernő Bóna, Milene Raquel Ramos Moreira e Sá, Juan Armando Rodriguez-Oballe, Andrea Jardi Cuadrado, József Hamvas, Judit Bajor, Alexander Schneider, Tiago Cúrdia Gonçalves, Haluk Tarik Kani, Alexandra Soós, Serge Chooklin, Marcus Hollenbach, Claudio Ricci, Marta Freitas, Isabel Miguel Salas, Michael Hirth, Cristina Tocia, Dóra Illés, Daniel de la Iglesia Garcia, Amir Gougol, Patrícia Sarlós, Marco Marino, Emőke Miklós, Qing Xia, Valentina Negoita, Mihailo Bezmarevic, Radislav Nakov, Erika Darvasi, Deniz Güney Duman, Péter Kanizsai, Laura Mastrangelo, Vasile Sandru, Andrea Párniczky, Hubert Zatorski, Andrea Szentesi, Mária Papp, Mario Pelaez-Luna, Marcel Tantau, Yliya Rabotyagova, Ferenc Izbéki, Natalia V Shirinskaya, Cristian Gheorghe, Ewa Małecka-Panas, Giedrius Barauskas, Engin Altintaş, Wei Huang, Ali Kchaou, Povilas Ignatavicius, Cezar Ciubotaru, Stefania Bunduc, Jorge Paulino Pereira, Dong Wu, Sabite Kacar, Alina Tantau, António Pedro Gomes, Svetlana Turcan, Bálint Erőss, Sorin T. Barbu, Adriana Gherbon, Georgi Minkov, Júlio Constantino, Márk Félix Juhász, Jimin Han, Serhii Chuklin, Klementina Ocskay, Mila Kovacheva-Slavova, Eugen Tcaciuc, Elio Jovine, Lilla Barbara Kincses, Ines Capunge, Gabriel Constantinescu, Bogdan Mateescu, Eugen Dumitru, Ming-Chu Chang, Andrea Soriano Rios, Márta Varga, László Czakó, Volkan Gökbulut, Alexandra Mikó, Szilárd Váncsa, Ahmed Tlili, Demcsak, Alexandra, Soos, Alexandra, Kincses, Lilla, Capunge, Ines, Minkov, Georgi, Kovacheva-Slavova, Mila, Nakov, Radislav, Wu, Dong, Huang, Wei, Xia, Qing, Deng, Lihui, Hollenbach, Marcus, Schneider, Alexander, Hirth, Michael, Ioannidis, Orestis, Vincze, Aron, Bajor, Judit, Sarlos, Patricia, Czako, Laszlo, Illes, Dora, Izbeki, Ferenc, Gajdan, Laszlo, Papp, Maria, Hamvas, Jozsef, Varga, Marta, Kanizsai, Peter, Bona, Erno, Miko, Alexandra, Vancsa, Szilard, Juhasz, Mark Felix, Ocskay, Klementina, Darvasi, Erika, Miklos, Emoke, Eross, Balint, Szentesi, Andrea, Parniczky, Andrea, Casadei, Riccardo, Ricci, Claudio, Ingaldi, Carlo, Mastrangelo, Laura, Jovine, Elio, Cennamo, Vincenzo, Marino, Marco V., Barauskas, Giedrius, Ignatavicius, Povilas, Pelaez-Luna, Mario, Rios, Andrea Soriano, Turcan, Svetlana, Tcaciuc, Eugen, Malecka-Panas, Ewa, Zatorski, Hubert, Nunes, Vitor, Gomes, Antonio, Goncalves, Tiago Curdia, Freitas, Marta, Constantino, Julio, Sa, Milene, Pereira, Jorge, Mateescu, Bogdan, Constantinescu, Gabriel, Sandru, Vasile, Negoi, Ionut, Ciubotaru, Cezar, Negoita, Valentina, Bunduc, Stefania, Gheorghe, Cristian, Barbu, Sorin, Tantau, Alina, Tantau, Marcel, Dumitru, Eugen, Suceveanu, Andra Iulia, Tocia, Cristina, Gherbon, Adriana, Litvin, Andrey, Shirinskaya, Natalia, Rabotyagova, Yliya, Bezmarevic, Mihailo, Hegyi, Peter Jeno, Han, Jimin, Rodriguez-Oballe, Juan Armando, Salas, Isabel Miguel, Comas, Eva Pijoan, de la Iglesia Garcia, Daniel, Cuadrado, Andrea Jardi, Castineira, Adriano Quiroga, Chang, Yu-Ting, Chang, Ming-Chu, Kchaou, Ali, Tlili, Ahmed, Kacar, Sabite, Gokbulut, Volkan, Duman, Deniz, Kani, Haluk Tarik, Altintas, Engin, Chooklin, Serge, Chuklin, Serhii, Gougol, Amir, Papachristou, George, Hegyi, Peter, Demcsak A., Soos A., Kincses L., Capunge I., Minkov G., Kovacheva-Slavova M., Nakov R., Wu D., Huang W., Xia Q., Deng L., Hollenbach M., Schneider A., Hirth M., Ioannidis O., Vincze A., Bajor J., Sarlos P., Czako L., Illes D., Izbeki F., Gajdan L., Papp M., Hamvas J., Varga M., Kanizsai P., Bona E., Miko A., Vancsa S., Juhasz M.F., Ocskay K., Darvasi E., Miklos E., Eross B., Szentesi A., Parniczky A., Casadei R., Ricci C., Ingaldi C., Mastrangelo L., Jovine E., Cennamo V., Marino M.V., Barauskas G., Ignatavicius P., Pelaez-Luna M., Rios A.S., Turcan S., Tcaciuc E., Malecka-Panas E., Zatorski H., Nunes V., Gomes A., Goncalves T.C., Freitas M., Constantino J., Sa M., Pereira J., Mateescu B., Constantinescu G., Sandru V., Negoi I., Ciubotaru C., Negoita V., Bunduc S., Gheorghe C., Barbu S., Tantau A., Tantau M., Dumitru E., Suceveanu A.I., Tocia C., Gherbon A., Litvin A., Shirinskaya N., Rabotyagova Y., Bezmarevic M., Hegyi P.J., Han J., Rodriguez-Oballe J.A., Salas I.M., Comas E.P., Garcia D.D.L.I., Cuadrado A.J., Castineira A.Q., Chang Y.-T., Chang M.-C., Kchaou A., Tlili A., Kacar S., Gokbulut V., Duman D., Kani H.T., Altintas E., Chooklin S., Chuklin S., Gougol A., Papachristou G., and Hegyi P.

Subjects
Male, Endocrinology, Diabetes and Metabolism, Gastroenterology, Cohort Studies, Feces, 0302 clinical medicine, Risk Factors, Surveys and Questionnaires, Acid suppressing drug, Acute pancreatitis, Gastrointestinal bleeding, Gastrointestinal infection, Proton pump inhibitor, Enterocolitis, Pseudomembranous, Aged, 80 and over, RISK, ASSOCIATION, Middle Aged, Clostridium difficile, CANCER, 3. Good health, Hospitalization, Treatment Outcome, 030220 oncology & carcinogenesis, Acute Disease, Female, 030211 gastroenterology & hepatology, Gastrointestinal Hemorrhage, Cohort study, Adult, medicine.medical_specialty, GI bleeding, medicine.drug_class, Proton-pump inhibitor, Infections, PROTON-PUMP INHIBITORS, 03 medical and health sciences, Internal medicine, mental disorders, medicine, MANAGEMENT, Humans, DRUGS, Acute pancreatiti, Aged, Retrospective Studies, Hepatology, Clostridioides difficile, business.industry, Proton Pump Inhibitors, medicine.disease, Pancreatitis, Acid suppression, business
Abstract

Background: Acid suppressing drugs (ASD) are generally used in acute pancreatitis (AP); however, large cohorts are not available to understand their efficiency and safety. Therefore, our aims were to evaluate the association between the administration of ASDs, the outcome of AP, the frequency of gastrointestinal (GI) bleeding and GI infection in patients with AP. Methods: We initiated an international survey and performed retrospective data analysis on AP patients hospitalized between January 2013 and December 2018. Results: Data of 17,422 adult patients with AP were collected from 59 centers of 23 countries. We found that 23.3% of patients received ASDs before and 86.6% during the course of AP. ASDs were prescribed to 57.6% of patients at discharge. ASD administration was associated with more severe AP and higher mortality. GI bleeding was reported in 4.7% of patients, and it was associated with pancreatitis severity, mortality and ASD therapy. Stool culture test was performed in 6.3% of the patients with 28.4% positive results. Clostridium difficile was the cause of GI infection in 60.5% of cases. Among the patients with GI infections, 28.9% received ASDs, whereas 24.1% were without any acid suppression treatment. GI infection was associated with more severe pancreatitis and higher mortality. Conclusions: Although ASD therapy is widely used, it is unlikely to have beneficial effects either on the outcome of AP or on the prevention of GI bleeding during AP. Therefore, ASD therapy should be substantially decreased in the therapeutic management of AP. (C) 2020 IAP and EPC. Published by Elsevier B.V.

Published
2020

11. EDUCATION IN GASTROENTOROLOGY.

Author

Durai, Rajaraman, Birch, David, Smira, Gabriela, Gheorghe, Liana, Gheorghe, Cristian, Becheanu, Gabriel, and Croitoru, Adina

Subjects
*GASTROENTEROLOGY, *INTERNAL medicine
Abstract

A quiz concerning gastroentrology is presented.

Published
2010

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