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186 results on '"Reinhart, Christoph"'

22. Publisher Correction: The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Author

Schweiker, Marcel, Abdul-Zahra, Amar, André, Maíra, Al-Atrash, Farah, Al-Khatri, Hanan, Alprianti, Rea Risky, Alsaad, Hayder, Amin, Rucha, Ampatzi, Eleni, Arsano, Alpha Yacob, Azadeh, Montazami, Azar, Elie, Bahareh, Bannazadeh, Batagarawa, Amina, Becker, Susanne, Buonocore, Carolina, Cao, Bin, Choi, Joon-Ho, Chun, Chungyoon, Daanen, Hein, Damiati, Siti Aisyah, Daniel, Lyrian, Vecchi, Renata De, Dhaka, Shivraj, Domínguez-Amarillo, Samuel, Dudkiewicz, Edyta, Edappilly, Lakshmi Prabha, Fernández-Agüera, Jesica, Folkerts, Mireille, Frijns, Arjan, Gaona, Gabriel, Garg, Vishal, Gauthier, Stephanie, Jabbari, Shahla Ghaffari, Harimi, Djamila, Hellwig, Runa T., Huebner, Gesche M., Jin, Quan, Jowkar, Mina, Kania, Renate, Kim, Jungsoo, King, Nelson, Kingma, Boris, Koerniawan, M. Donny, Kolarik, Jakub, Kumar, Shailendra, Kwok, Alison, Lamberts, Roberto, Laska, Marta, Lee, M. C. Jeffrey, Lee, Yoonhee, Lindermayr, Vanessa, Mahaki, Mohammadbagher, Marcel-Okafor, Udochukwu, Marín-Restrepo, Laura, Marquardsen, Anna, Martellotta, Francesco, Mathur, Jyotirmay, McGill, Gráinne, Mino-Rodriguez, Isabel, Mou, Di, Moujalled, Bassam, Nakajima, Mia, Ng, Edward, Okafor, Marcellinus, Olweny, Mark, Ouyang, Wanlu, Papst de Abreu, Ana Ligia, Pérez-Fargallo, Alexis, Rajapaksha, Indrika, Ramos, Greici, Rashid, Saif, Reinhart, Christoph F., Rivera, Ma. Isabel, Salmanzadeh, Mazyar, Schakib-Ekbatan, Karin, Schiavon, Stefano, Shooshtarian, Salman, Shukuya, Masanori, Soebarto, Veronica, Suhendri, Tahsildoost, Mohammad, Tartarini, Federico, Teli, Despoina, Tewari, Priyam, Thapa, Samar, Trebilcock, Maureen, Trojan, Jörg, Tukur, Ruqayyatu B., Voelker, Conrad, Yam, Yeung, Yang, Liu, Zapata-Lancaster, Gabriela, Zhai, Yongchao, Zhu, Yingxin, and Zomorodian, Zahra Sadat

Published
2020
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31. The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Author

Schweiker, Marcel, Abdul-Zahra, Amar, André, Maíra, Al-Atrash, Farah, Al-Khatri, Hanan, Alprianti, Rea Risky, Alsaad, Hayder, Amin, Rucha, Ampatzi, Eleni, Arsano, Alpha Yacob, Azadeh, Montazami, Azar, Elie, Bahareh, Bannazadeh, Batagarawa, Amina, Becker, Susanne, Buonocore, Carolina, Cao, Bin, Choi, Joon-Ho, Chun, Chungyoon, Daanen, Hein, Damiati, Siti Aisyah, Daniel, Lyrian, Vecchi, Renata De, Dhaka, Shivraj, Domínguez-Amarillo, Samuel, Dudkiewicz, Edyta, Edappilly, Lakshmi Prabha, Fernández-Agüera, Jesica, Folkerts, Mireille, Frijns, Arjan, Gaona, Gabriel, Garg, Vishal, Gauthier, Stephanie, Jabbari, Shahla Ghaffari, Harimi, Djamila, Hellwig, Runa T., Huebner, Gesche M., Jin, Quan, Jowkar, Mina, Kania, Renate, Kim, Jungsoo, King, Nelson, Kingma, Boris, Koerniawan, M. Donny, Kolarik, Jakub, Kumar, Shailendra, Kwok, Alison, Lamberts, Roberto, Laska, Marta, Lee, M. C. Jeffrey, Lee, Yoonhee, Lindermayr, Vanessa, Mahaki, Mohammadbagher, Marcel-Okafor, Udochukwu, Marín-Restrepo, Laura, Marquardsen, Anna, Martellotta, Francesco, Mathur, Jyotirmay, McGill, Gráinne, Mino-Rodriguez, Isabel, Mou, Di, Moujalled, Bassam, Nakajima, Mia, Ng, Edward, Okafor, Marcellinus, Olweny, Mark, Ouyang, Wanlu, Papst de Abreu, Ana Ligia, Pérez-Fargallo, Alexis, Rajapaksha, Indrika, Ramos, Greici, Rashid, Saif, Reinhart, Christoph F., Rivera, Ma. Isabel, Salmanzadeh, Mazyar, Schakib-Ekbatan, Karin, Schiavon, Stefano, Shooshtarian, Salman, Shukuya, Masanori, Soebarto, Veronica, Suhendri, Tahsildoost, Mohammad, Tartarini, Federico, Teli, Despoina, Tewari, Priyam, Thapa, Samar, Trebilcock, Maureen, Trojan, Jörg, Tukur, Ruqayyatu B., Voelker, Conrad, Yam, Yeung, Yang, Liu, Zapata-Lancaster, Gabriela, Zhai, Yongchao, Zhu, Yingxin, and Zomorodian, Zahra Sadat

Published
2019
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41. Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules.

Author

Schleker, E. Sabine M., Buschmann, Sabine, Hao Xie, Sonja Welsch, Michel, Hartmut, and Reinhart, Christoph

Subjects
ATP-binding cassette transporters, PICHIA pastoris, MEMBRANE proteins, ELECTRON cryomicroscopy, ADENOSINE triphosphate, PERMEATION tubes, TELEVISION networks
Abstract

Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are multidomain transmembrane proteins, which facilitate the transport of various substances across cell membranes using energy derived from ATP hydrolysis. They are important drug targets since they mediate decreased drug susceptibility during pharmacological treatments. For the methylotrophic yeast Pichia pastoris, a model organism that is a widely used host for protein expression, the role and function of its ABC transporters is unexplored. In this work, we investigated the Pichia ABC-B transporter STE6-2p. Functional investigations revealed that STE6-2p is capable of transporting rhodamines in vivo and is active in the presence of verapamil and triazoles in vitro. A phylogenetic analysis displays homology among multidrug resistance (MDR) transporters from pathogenic fungi to human ABC-B transporters. Further, we present high-resolution single-particle electron cryomicroscopy structures of an ABC transporter from P. pastoris in the apo conformation (3.1 Å) and in complex with verapamil and adenylyl imidodiphosphate (AMP-PNP) (3.2 Å). An unknown density between transmembrane helices 4, 5, and 6 in both structures suggests the presence of a sterol-binding site of unknown function. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Publisher Correction:The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

Author

Schweiker, Marcel, Abdul-Zahra, Amar, André, Maíra, Al-Atrash, Farah, Al-Khatri, Hanan, Alprianti, Rea Risky, Alsaad, Hayder, Amin, Rucha, Ampatzi, Eleni, Arsano, Alpha Yacob, Azadeh, Montazami, Azar, Elie, Bahareh, Bannazadeh, Batagarawa, Amina, Becker, Susanne, Buonocore, Carolina, Cao, Bin, Choi, Joon Ho, Chun, Chungyoon, Daanen, Hein, Damiati, Siti Aisyah, Daniel, Lyrian, De Vecchi, Renata, Dhaka, Shivraj, Domínguez Amarillo, Samuel, Dudkiewicz, Edyta, Edappilly, Lakshmi Prabha, Fernández-Agüera Escudero, Jessica, Folkerts, Mireille, Frijns, Arjan, Gaona, Gabriel, Garg, Vishal, Gauthier, Stephanie, Jabbari, Shahla Ghaffari, Harimi, Djamila, Hellwig, Runa T., Huebner, Gesche M., Jin, Quan, Jowkar, Mina, Kania, Renate, Kim, Jungsoo, King, Nelson, Kingma, Boris, Koerniawan, M. Donny, Kolarik, Jakub, Kumar, Shailendra, Kwok, Alison, Lamberts, Roberto, Laska, Marta, Lee, M. C.Jeffrey, Lee, Yoonhee, Lindermayr, Vanessa, Mahaki, Mohammadbagher, Marcel-Okafor, Udochukwu, Marín Restrepo, Laura, Marquardsen, Anna, Martellotta, Francesco, Mathur, Jyotirmay, McGill, Gráinne, Mino Rodríguez, Isabel, Mou, Di, Moujalled, Bassam, Nakajima, Mia, Ng, Edward, Okafor, Marcellinus, Olweny, Mark, Ouyang, Wanlu, Papst de Abreu, Ana Lígia, Pérez Fargallo, Alexis, Rajapaksha, Indrika, Ramos, Greici, Rashid, Saif, Reinhart, Christoph F., Rivera, María Isabel, Salmanzadeh, Mazyar, Schakib-Ekbatan, Karin, Schiavon, Stefano, Shooshtarian, Salman, Shukuya, Masanori, Soebarto, Veronica, Suhendri, Suhendri, Tahsildoost, Mohammad, Tartarini, Federico, Teli, Despoina, Tewari, Priyam, Thapa, Samar, Trebilcock, Maureen, Trojan, Jörg, Tukur, Ruqayyatu B., Voelker, Conrad, Yam, Yeung, Yang, Liu, Zapata Lancaster, Gabriela, Zhai, Yongchao, Zhu, Yingxin, Zomorodian, Zahra Sadat, Universidad de Sevilla. Departamento de Construcciones Arquitectónicas I (ETSA), and Universidad de Sevilla. TEP130: Arquitectura, Patrimonio y Sostenibilidad: Acústica, Iluminación, Óptica y Energía

Published
2020

43. Erratum: Publisher Correction: The Scales Project, a cross-national dataset on the interpretation of thermal perception scales (Scientific data (2019) 6 1 (289))

Author

Schweiker, Marcel, Abdul-Zahra, Amar, André, Maíra, Al-Atrash, Farah, Al-Khatri, Hanan, Alprianti, Rea Risky, Alsaad, Hayder, Amin, Rucha, Ampatzi, Eleni, Arsano, Alpha Yacob, Azadeh, Montazami, Azar, Elie, Bahareh, Bannazadeh, Batagarawa, Amina, Becker, Susanne, Buonocore, Carolina, Cao, Bin, Choi, Joon Ho, Chun, Chungyoon, Daanen, Hein, Damiati, Siti Aisyah, Daniel, Lyrian, Vecchi, Renata De, Dhaka, Shivraj, Domínguez-Amarillo, Samuel, Dudkiewicz, Edyta, Edappilly, Lakshmi Prabha, Fernández-Agüera, Jesica, Folkerts, Mireille, Frijns, Arjan, Gaona, Gabriel, Garg, Vishal, Gauthier, Stephanie, Jabbari, Shahla Ghaffari, Harimi, Djamila, Hellwig, Runa T., Huebner, Gesche M., Jin, Quan, Jowkar, Mina, Kania, Renate, Kim, Jungsoo, King, Nelson, Kingma, Boris, Koerniawan, M. Donny, Kolarik, Jakub, Kumar, Shailendra, Kwok, Alison, Lamberts, Roberto, Laska, Marta, Lee, M. C.Jeffrey, Lee, Yoonhee, Lindermayr, Vanessa, Mahaki, Mohammadbagher, Marcel-Okafor, Udochukwu, Marín-Restrepo, Laura, Marquardsen, Anna, Martellotta, Francesco, Mathur, Jyotirmay, McGill, Gráinne, Mino-Rodriguez, Isabel, Mou, Di, Moujalled, Bassam, Nakajima, Mia, Ng, Edward, Okafor, Marcellinus, Olweny, Mark, Ouyang, Wanlu, Papst de Abreu, Ana Ligia, Pérez-Fargallo, Alexis, Rajapaksha, Indrika, Ramos, Greici, Rashid, Saif, Reinhart, Christoph F., Rivera, Ma Isabel, Salmanzadeh, Mazyar, Schakib-Ekbatan, Karin, Schiavon, Stefano, Shooshtarian, Salman, Shukuya, Masanori, Soebarto, Veronica, Suhendri, Tahsildoost, Mohammad, Tartarini, Federico, Teli, Despoina, Tewari, Priyam, Thapa, Samar, Trebilcock, Maureen, Trojan, Jörg, Tukur, Ruqayyatu B., Voelker, Conrad, Yam, Yeung, Yang, Liu, Zapata-Lancaster, Gabriela, Zhai, Yongchao, Zhu, Yingxin, Zomorodian, Zahra Sadat, Physiology, and Amsterdam Movement Sciences

Subjects
SDG 16 - Peace, SDG 16 - Peace, Justice and Strong Institutions, Justice and Strong Institutions
Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Published
2020

45. Lightswitch-2002: a model for manual and automated control of electric lighting and blinds

Author

Reinhart, Christoph F.

Subjects
Electric lighting -- Research, Lighting -- Research, Earth sciences, Petroleum, energy and mining industries
Abstract

A simulation algorithm is proposed that predicts the lighting energy performance of manually and automatically controlled electric lighting and blind systems in private and two-person offices. Algorithm inputs are annual profiles of user occupancy and work plane illuminances. These two inputs are combined with probabilistic switching patterns, which have been derived from field data, in order to predict the status of the electric lighting and blinds throughout the year. The model features four different user types to mimic variation in control behavior between different occupants. An example application in a private office with a southern facade yields that--depending on the user type--the electric lighting energy demand for a manually controlled electric lighting and blind system ranges from 10 to 39 kW h/ [m.sup.2] yr. The predicted mean energy savings of a switch-off occupancy sensor in the example office are 20%. Depending on how reliably occupants switch off a dimmed lighting system, mean electric lighting energy savings due to a daylight-linked photocell control range from 60% to zero. Keywords: Lighting controls; Daylighting; User behavior models

Published
2004

49. Experimental validation of Autodesk[R] 3ds Max[R] Design 2009 and Daysim 3.0

Author

Reinhart, Christoph and Breton, Pierre-Felix

Subjects
Electric lighting -- Research, Lighting -- Research, Radiance -- Research, Engineering -- Computer programs, Engineering -- Usage, Engineering software, Engineering and manufacturing industries, Autodesk 3ds Max Design (Simulation software) -- Usage, Autodesk Daysim 3.0 (Simulation software) -- Usage
Abstract

This article compares daylight simulation results generated with two simulation programs, Autodesk[R] 3ds Max[R] Design 2009 (3ds Max Design) and Daysim 3.0 (Daysim), to indoor illuminance measurements in a sidelit space. The sidelit space was in a single location, but was configured with five fenestration and glazing options, and operated under a variety of sky conditions. The measurements form a set of 'daylighting test cases' that were recently developed to evaluate the simulation capabilities and limitations of different daylight simulation programs. Both 3ds Max Design and Daysim were given external direct and diffuse irradiances as simulation input, from which the programs predicted indoor illuminances on a grid of upward facing work plane sensors and downward facing ceiling sensors. 3ds Max Design is based on Exposure[TM] technology, a lighting analysis module that includes a 'shader' of the Perez sky model and that uses the mental ray[R] raytracer for the global illumination calculation. Daysim also uses the Perez sky model and is based on the Radiance backward raytracer combined with a daylight coefficient approach. The comparison of both programs with measurements demonstrated that 3ds Max Design simulated indoor illuminances for the daylighting test cases with reliability comparable to Daysim. Most mean bias errors and root mean square errors were in the range of those reported in earlier validation studies: both programs succeeded in reproducing measurements for a sidelit space with and without a lightshef. While 3ds Max Design consistently underestimated the incoming light flux going through a translucent panel, Daysim results were lower than measurements for the internal venetian blind test case. The results suggest that the accuracy of both programs is sufficient for typical daylighting design investigations of spaces with complexity comparable to the five daylighting test cases. Keywords--daylight simulation, validation, Radiance, 3ds Max., 1 INTRODUCTION The Radiance backward raytracer is a lighting simulation program that was initially developed by Greg Ward in the late 1980s at Lawrence Berkeley National Laboratory (Ward and Rubinstein [...]

Published
2009

50. Identification of potential novel interacting partners for coagulation factor xiii b (fxiii-b) subunit, a protein associated with a rare bleeding disorder

Author

Singh, Sneha, Akhter, Mohammad Suhail, Dodt, Johannes, Volkers, Peter, Reuter, Andreas, Reinhart, Christoph, Krettler, Christoph, Oldenburg, Johannes, and Biswas, Arijit

Subjects
ddc:570
Abstract

Coagulation factor XIII (FXIII) is a plasma-circulating heterotetrameric pro-transglutaminase complex that is composed of two catalytic FXIII-A and two protective/regulatory FXIII-B subunits. FXIII acts by forming covalent cross-links within a preformed fibrin clots to prevent its premature fibrinolysis. The FXIII-A subunit is known to have pleiotropic roles outside coagulation, but the FXIII-B subunit is a relatively unexplored entity, both structurally as well as functionally. Its discovered roles so far are limited to that of the carrier/regulatory protein of its partner FXIII-A subunit. In the present study, we have explored the co-presence of protein excipients in commercial FXIII plasma concentrate FibrogamminP by combination of protein purification and mass spectrometry-based verification. Complement factor H was one of the co-excipients observed in this analysis. This was followed by performing pull down assays from plasma in order to detect the putative novel interacting partners for the FXIII-B subunit. Complement system proteins, like complement C3 and complement C1q, were amongst the proteins that were pulled down. The only protein that was observed in both experimental set ups was alpha-2-macroglobulin, which might therefore be a putative interacting partner of the FXIII/FXIII-B subunit. Future functional investigations will be needed to understand the physiological significance of this association.

Published
2019

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