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1. Hemoglobin variant common to Chinese and North American Indians: alpha-2-beta-22 Glu-Ala.

Author

Blackwell RW, Liu CS, Yang HJ, Wang CC, and Huang JT

Subjects
Alanine, Amino Acid Sequence, Asian People, Blood Protein Electrophoresis, Canada, Chromatography, Paper, Glutamates, Humans, Indians, North American, Taiwan, Texas, Hemoglobins, Abnormal analysis, Peptides analysis
Abstract

An electrophoretically slow hemoglobin variant, in which the structural change involves the replacement of a glutamyl residue by alanyl at position beta-22, was reported in two groups of North American Indians: hemoglobin-G Coushatta, in Alabama-Coushatta Indians in Texas; and hemoglobin-G Saskatoon, in descendants of Santee Indians living in Canada. Hemoglobin-G Hsin-Chu, found in Taiwan in a Chinese from the northern Chinese province of Liaoning, is now shown to have the same structural anomaly.

Published
1968
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