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Lung cancer is an uncontrolled growth of tissue causing a lump in the human lung. If lung cancer can be detected early, it can increase the survival rate. Therefore, a multi-classification approach of lung nodule detection with high computational effectiveness is required. In this paper, a multi-classification approach of lung nodule detection and classification is proposed using artificial intelligence on computed tomography (CT) scan images. Different preprocessing steps are applied for resizing, smoothing, and enhancement of the CT images. Then, two different approaches for feature extraction using VGG16 transfer learning and morphological segmentation are proposed. Morphological segmentation and feature extraction are applied for the segmentation of the region of interest and to extract the distinct features. Finally, the proposed deep learning architecture and seven different machine learning algorithms are applied on the preprocessed data and the extracted features for the classification of lung nodules into three classes: malignant, benign, and normal. It is observed that the stacked ensemble model of deep learning convolutional neural network (CNN) and VGG16 transfer learning models (CNN+VGG16) can achieve 99.55% accuracy using preprocessed data. It is also observed that all the ML algorithms perform with reasonably high accuracy using the low-dimensional morphological features. It is observed from the fivefold cross-validation results that logistic regression performs with 99.36% accuracy in 23.71 s time using the preprocessed data. Whereas, using the morphological features, k-nearest neighbor, and the support vector machine perform with the highest accuracy of 99.76% with very reduced computational time of 0.017 and 0.008 s, respectively. [ABSTRACT FROM AUTHOR]

Microelectronics production failure analysis is an important step in improving product quality and development. In fact, the understanding of the failure mechanisms and therefore the implementation of corrective actions on the cause of the failure depend on the results of this analysis. These analyses are saved under textual features format. Then such data need first to be preprocessed and vectorized (converted to numeric). Second, to overcome the curse of dimensionality caused by the vectorisation process, a dimension reduction is applied. A two-stage variable selection and feature extraction is used to reduce the high dimensionality of a feature space. We are first interested in studying the potential of using an unsupervised variable selection technique, the genetic algorithm, to identify the variables that best demonstrate discrimination in the separation and compactness of groups of textual data. The genetic algorithm uses a combination of the K-means or Gaussian Mixture Model clustering and validity indices as a fitness function for optimization. Such a function improves both compactness and class separation. The second work looks into the feasibility of applying a feature extraction technique. The adopted methodology is a Deep learning algorithm based on variational autoencoder (VAE) for latent space disentanglement and Gaussian Mixture Model for clustering of the latent space for cluster identification. The last objective of this paper is to propose a new methodology based on the combination between variational autoencoder (VAE) for the latent space disentanglement, and genetic algorithm (GA) to find, in an unsupervised way, the latent variables allowing the best discrimination of clusters of failure analysis data. This methodology is called VAE-GA. Experiments on textual datasets of failure analysis demonstrate the effectiveness of the VAE-GA proposed method which allows better discrimination of textual classes compared to the use of GA or VAE separately or the combination of PCA with GA (PCA-GA) or a simple Auto-encoders with GA (AE-GA). [ABSTRACT FROM AUTHOR]

Purpose: To propose a new quality scoring tool, METhodological RadiomICs Score (METRICS), to assess and improve research quality of radiomics studies. Methods: We conducted an online modified Delphi study with a group of international experts. It was performed in three consecutive stages: Stage#1, item preparation; Stage#2, panel discussion among EuSoMII Auditing Group members to identify the items to be voted; and Stage#3, four rounds of the modified Delphi exercise by panelists to determine the items eligible for the METRICS and their weights. The consensus threshold was 75%. Based on the median ranks derived from expert panel opinion and their rank-sum based conversion to importance scores, the category and item weights were calculated. Result: In total, 59 panelists from 19 countries participated in selection and ranking of the items and categories. Final METRICS tool included 30 items within 9 categories. According to their weights, the categories were in descending order of importance: study design, imaging data, image processing and feature extraction, metrics and comparison, testing, feature processing, preparation for modeling, segmentation, and open science. A web application and a repository were developed to streamline the calculation of the METRICS score and to collect feedback from the radiomics community. Conclusion: In this work, we developed a scoring tool for assessing the methodological quality of the radiomics research, with a large international panel and a modified Delphi protocol. With its conditional format to cover methodological variations, it provides a well-constructed framework for the key methodological concepts to assess the quality of radiomic research papers. Critical relevance statement: A quality assessment tool, METhodological RadiomICs Score (METRICS), is made available by a large group of international domain experts, with transparent methodology, aiming at evaluating and improving research quality in radiomics and machine learning. Key points: • A methodological scoring tool, METRICS, was developed for assessing the quality of radiomics research, with a large international expert panel and a modified Delphi protocol. • The proposed scoring tool presents expert opinion-based importance weights of categories and items with a transparent methodology for the first time. • METRICS accounts for varying use cases, from handcrafted radiomics to entirely deep learning-based pipelines. • A web application has been developed to help with the calculation of the METRICS score (https://metricsscore.github.io/metrics/METRICS.html) and a repository created to collect feedback from the radiomics community (https://github.com/metricsscore/metrics). [ABSTRACT FROM AUTHOR]