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This research presents a novel patch antenna prototype that operates in the THz range for early detection of malignant cancerous cells. The antenna has dimensions of 100 µm × 100 µm and achieves −27.3 dB return loss at an operating frequency of 2.34 THz. The proposed sensor is optimized for a polyimide substrate with a dielectric constant of 3.5 and thickness of 15.7 µm. The prototype's sensitivity and performance are evaluated by simulating different malignant neoplasms using High-Frequency Simulation Software (HFSS) for five types of breast cancer cells. The results indicate that the variation in resonant frequency and the S21 parameter between malignant cells and healthy breast cells are the primary factors that determine the sensitivity of the prototype. The proposed patch antenna's high sensitivity and low profile make it a promising solution for the early detection and prognosis of cancerous cells. [ABSTRACT FROM AUTHOR]