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The significant risk associated with fault reactivation often necessitates slip tendency analyses for effective risk assessment. However, such analyses are challenging, particularly in large areas with limited or absent reliable stress measurements and where the cost of extensive geomechanical analyses or simulations is prohibitive. In this paper, we propose a novel approach using a physics‐informed neural network that integrates stress orientation and satellite displacement observations in a top‐down multi‐scale framework to estimate two‐dimensional slip tendency analyses even in regions lacking comprehensive stress data. Our study demonstrates that velocities derived from a continental scale analysis, combined with reliable stress orientation averages, can effectively guide models at smaller scales to generate qualitative slip tendency maps. By offering customizable data selection and stress resolution options, this method presents a robust solution to address data scarcity issues, as exemplified through a case study of the South Australian Eyre Peninsula. Plain Language Summary: Fault reactivation poses significant risks, often requiring slip tendency analyses for thorough risk assessment. Yet, such analyses face challenges, especially in large areas lacking reliable stress measurements or where extensive geomechanical analyses are too costly. Our paper suggests a new method using a physics‐based neural network. This approach combines compressive direction and satellite displacement observations to estimate slip tendencies in two dimensions, even where stress data is lacking. Our study shows that by using displacements from a continental scale analysis and reliable averages of compressive directions, we can guide models to create smaller‐scale maps indicating where faults are more likely to reactivate. This method allows for customizable data selection and stress resolution, offering a strong solution to data scarcity issues. We demonstrate its effectiveness through a case study of South Australia's Eyre Peninsula. Key Points: Physics‐based neural networks allow two‐dimensional slip tendency analyses without prior full‐stress informationA multi‐scale approach provides required displacement constraints when inferring full stresses from global navigation satellite system (GNSS) and stress orientation dataWe present a new application for GNSS data that would welcome more stations, even in seismically stable areas [ABSTRACT FROM AUTHOR]