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1 results on '"ZHU Jun"'

1. Successful treatment of a case with synchronous follicular lymphoma and gastric adenocarcinoma with CD19 CAR T cells and literature review.

Author

Liu, Jiaxin, Cao, Fang, Li, Zhemin, Gao, Hongye, Zhang, Chen, Du, Tingting, Li, Ziyu, Song, Yuqin, Zhu, Jun, and Ying, Zhitao

Subjects
*STOMACH tumors, *ADENOCARCINOMA, *CELLULAR therapy, *CELL receptors, *TREATMENT effectiveness, *T cells, *DISEASE remission
Abstract

What is known and objective: Anti‐CD19 CAR‐T cell therapy is effective in B‐cell lymphoma. However, it is rarely used in lymphoma combined with other malignant tumours. Case description: A relapsed/refractory follicular lymphoma (r/r FL) patient underwent anti‐CD19 CAR‐T cell therapy and achieved complete response to lymphoma. However, gastric adenocarcinoma (GAC) was diagnosed during the cellular therapy. After infusion of CAR‐T cells, he received curative treatment for GAC, and maitained complete response in both r/r FL and GAC after the treatment. What is new and conclusion: Anti‐CD19 CAR‐T therapy is an effective treatment for r/r FL, also provided opportunity for the sequential therapy of GAC, and remained significant quality of life afterwards. [ABSTRACT FROM AUTHOR]

Published
2022
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