1. Outbreak Investigation of NADC30-Like PRRSV in South-East China.
- Author
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Li, C., Zhuang, J., Wang, J., Han, L., Sun, Z., Xiao, Y., Ji, G., Li, Y., Tan, F., Li, X., and Tian, K.
- Subjects
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PORCINE reproductive & respiratory syndrome , *DISEASE outbreaks , *DISEASE prevalence , *PHYLOGENY - Abstract
Epidemiological outbreak investigations were conducted on NADC30-like porcine reproductive and respiratory syndrome virus ( PRRSV) to investigate the prevalence of the disease in south-east China in 2015. Two more provinces were found to have NADC30-like PRRSV circulating besides previously reported six provinces. Phylogenetic analysis showed that these virus isolates were clustered in an independent branch and shared high nucleotide similarity to NADC30, a type 2 PRRSV that has been isolated in Unite States in 2008. One NADC30-like PRRSV strain from Henan province was successfully isolated on porcine alveolar macrophages and was tested on 6-week-old specific pathogen-free pigs for pathogenic study. The virus-inoculated pigs showed typical PRRSV clinical symptoms, but all pigs survived throughout the study with a period of 14 days. At necropsy, the lungs of infected pigs developed PRRSV-specific interstitial pneumonia, and virus antigen was detected in lung samples. Therefore, our results indicated NADC30-like PRRSV has widely spread in China and could cause clinical disease on pigs. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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