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In this paper, we study the effect of the amplitude of input shaking on the dynamic response of a loess-mudstone slope through a series of staged centrifuge tests, including different amplitude earthquake excitations, in which the seismic performance of the slope models was analyzed and investigated. The derived outputs were processed to study the earthquake acceleration amplification effect and to assess the induced deformation mechanism in terms of the resulting displacements and deformation mode. The test results indicated that the amplification factors of peak ground acceleration (PGA) increased with increasing slope height, reaching maximum values at the crest. The amplification effect was also demonstrated on the slope surface. In addition, the predominant amplitude of the input seismic excitation was critical to the response of the slope. The results proved that the displacements in the loess layer were much larger than those in the weathered mudstone. Tensile cracks were formed mainly on the crest and the upper part of the slope, and failure modes were dominant at the slope surface. The location of the slide plane in the model was consistent with the location of maximum acceleration. A continuous shallow slide plane was formed in the loess layer. The analysis provides good information for identifying both surface movement and mass movement. [ABSTRACT FROM AUTHOR]