1. Evaluation of Renal Impairment in Patients with Diabetic Kidney Disease by Integrated Chinese and Western Medicine.
- Author
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Qu, Yi-lun, Dong, Zhe-yi, Cheng, Hai-mei, Liu, Qian, Wang, Qian, Yang, Hong-tao, Mao, Yong-hui, Li, Ji-jun, Liu, Hong-fang, Geng, Yan-qiu, Huang, Wen, Liu, Wen-hu, Xie, Hui-di, Peng, Fei, Li, Shuang, Jiang, Shuang-shuang, Li, Wei-zhen, Duan, Shu-wei, Feng, Zhe, and Zhang, Wei-guang
- Subjects
KIDNEY disease risk factors ,MEDICINE ,HOSPITALS ,CHRONIC kidney failure ,HYPERURICEMIA ,RISK assessment ,SEVERITY of illness index ,ATHEROSCLEROSIS ,ANEMIA ,LOGISTIC regression analysis ,SOCIODEMOGRAPHIC factors ,ODDS ratio ,DIABETIC nephropathies ,CHINESE medicine ,ALBUMINURIA ,DISEASE complications - Abstract
Objective: To investigate the factors related to renal impairment in patients with diabetic kidney disease (DKD) from the perspective of integrated Chinese and Western medicine. Methods: Totally 492 patients with DKD in 8 Chinese hospitals from October 2017 to July 2019 were included. According to Kidney Disease Improving Global Outcomes (KDIGO) staging guidelines, patients were divided into a chronic kidney disease (CKD) 1–3 group and a CKD 4–5 group. Clinical data were collected, and logistic regression was used to analyze the factors related to different CKD stages in DKD patients. Results: Demographically, male was a factor related to increased CKD staging in patients with DKD (OR=3.100, P=0.002). In clinical characteristics, course of diabetes >60 months (OR=3.562, P=0.010), anemia (OR=4.176, P<0.001), hyperuricemia (OR=3.352, P<0.001), massive albuminuria (OR=4.058, P=0.002), atherosclerosis (OR=2.153, P=0.007) and blood deficiency syndrome (OR=1.945, P=0.020) were factors related to increased CKD staging in patients with DKD. Conclusions: Male, course of diabetes >60 months, anemia, hyperuricemia, massive proteinuria, atherosclerosis, and blood deficiency syndrome might indicate more severe degree of renal function damage in patients with DKD. (Registration No. NCT03865914) [ABSTRACT FROM AUTHOR]
- Published
- 2023
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