10 results on '"Burke, Thomas F."'
Search Results
2. A low-cost uterine balloon tamponade for management of postpartum hemorrhage: modeling the potential impact on maternal mortality and morbidity in sub-Saharan Africa.
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Herrick, Tara, Mvundura, Mercy, Burke, Thomas F., and Abu-Haydar, Elizabeth
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PUERPERAL disorders ,PREGNANCY complications ,HEMORRHAGE ,MATERNAL mortality ,POSTMORTEM birth ,HEMORRHAGE treatment ,FORECASTING ,SURGICAL hemostasis ,THERAPEUTICS ,PREVENTION - Abstract
Background: Postpartum hemorrhage (PPH) is the leading cause of maternal deaths worldwide. This study sought to quantify the potential health impact (morbidity and mortality reductions) that a low-cost uterine balloon tamponade (UBT) could have on women suffering from uncontrolled PPH due to uterine atony in sub-Saharan Africa.Methods: The Maternal and Neonatal Directed Assessment of Technology (MANDATE) model was used to estimate maternal deaths, surgeries averted, and cases of severe anemia prevented through UBT use among women with PPH who receive a uterotonic drug but fail this therapy in a health facility. Estimates were generated for the year 2018. The main outcome measures were lives saved, surgeries averted, and severe anemia prevented.Results: The base case model estimated that widespread use of a low-cost UBT in clinics and hospitals could save 6547 lives (an 11% reduction in maternal deaths), avert 10,823 surgeries, and prevent 634 severe anemia cases in sub-Saharan Africa annually.Conclusions: A low-cost UBT has a strong potential to save lives and reduce morbidity. It can also potentially reduce costly downstream interventions for women who give birth in a health care facility. This technology may be especially useful for meeting global targets for reducing maternal mortality as identified in Sustainable Development Goal 3. [ABSTRACT FROM AUTHOR]- Published
- 2017
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3. Shock progression and survival after use of a condom uterine balloon tamponade package in women with uncontrolled postpartum hemorrhage.
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Burke, Thomas F., Danso ‐ Bamfo, Sandra, Guha, Moytrayee, Oguttu, Monica, Tarimo, Vincent, and Nelson, Brett D.
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UTERINE hemorrhage , *PUERPERAL disorders , *PREGNANCY complications , *BLOOD pressure , *PSYCHOLOGY of women , *DISEASE progression - Abstract
Objective: To examine the outcomes of women in advanced shock from uncontrolled postpartum hemorrhage (PPH) who underwent placement of an Every Second Matters for Mothers and Babies Uterine Balloon Tamponade (ESM-UBT) device.Methods: In a prospective case series, data were collected for women who received an ESM-UBT device at healthcare facilities in Kenya, Senegal, Sierra Leone, and Tanzania between September 1, 2012, and September 30, 2016. Shock class was assigned on the basis of recorded blood pressures and mental status at the time of UBT placement.Results: Data for 306 women with uncontrolled PPH from uterine atony across 117 facilities were analyzed. Normal vital signs or class I/II shock were reported for 166 (54.2%). In this group, one death occurred and was attributed to PPH (survival rate 99.4%). There were no cases of shock progression. One hundred and eleven (36.3%) were in class III shock and 29 (9.5%) in class IV shock; the respective survival rates were 97.3% (n=108) and 86.2% (n=25).Conclusion: The ESM-UBT device arrests hemorrhage, prevents shock progression, and is associated with high survival rates among women with uncontrolled PPH from uterine atony. [ABSTRACT FROM AUTHOR]- Published
- 2017
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4. Use of prophylactic uterotonics during the third stage of labor: a survey of provider practices in community health facilities in Sierra Leone.
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Natarajan, Abirami, Ahn, Roy, Nelson, Brett D., Eckardt, Melody, Kamara, Jennifer, Kargbo, S. A. S., Kanu, Pity, Burke, Thomas F., and Kargbo, Sas
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MATERNAL mortality ,LABOR (Obstetrics) ,DELIVERY (Obstetrics) ,OXYTOCIN ,HEMORRHAGE ,MORTALITY risk factors ,THIRD stage of labor (Obstetrics) ,HEMORRHAGE prevention ,PUERPERAL disorders ,OXYTOCICS ,COMMUNITY health services ,MEDICAL personnel ,MIDWIFERY ,QUALITATIVE research ,CROSS-sectional method ,PREVENTION ,THERAPEUTICS ,PSYCHOLOGY - Abstract
Background: Postpartum hemorrhage remains the leading cause of maternal mortality worldwide. Administration of uterotonics during the third stage of labor is a simple and well established intervention that can significantly decrease the development of postpartum hemorrhage. Little is known about the use of prophylactic uterotonics in peripheral health centers, where the majority of normal deliveries occur. The purpose of this study is to assess health provider current practices and determinants to the use of prophylactic uterotonics in Sierra Leone, a country with one of the highest maternal mortality ratios worldwide.Methods: This is a mixed methods study using descriptive cross-sectional survey and qualitative interviews in community health facilities in Freetown, Sierra Leone following a comprehensive training on postpartum hemorrhage. Facilities and providers were surveyed between May and June 2014. Qualitative methods were used to identify barriers and facilitators to the use of prophylactic uterotonics.Results: A total of 134 providers were surveyed at 39 periphreal health facilities. Thirteen facilities (39 %) reported an inconsistent supply of oxytocin. The majority of facilities (64 %) stored oxytocin at room temperature. Provider level, in-service training, and leadership role were significantly associated with prophylactic uterotonic use. Overall, 62 % of providers reported routine use. Midwives were most likely to routinely administer uterotonics (93 %), followed by community health officers/assistants (78 %), maternal and child health aides (56 %), and state-enrolled community health nurses (52 %). Of the providers who received in-service training, 67 % reported routine use; of those with no in-service training, 42 % reported routine use. Qualitative analysis revealed that facility protocols, widespread availability, and provider perception of utility facilitated routine use. Common barriers reported included inconsistent supply of uterotonics, lack of knowledge regarding timely administration, and provider attitude regarding utility of uterotonics following normal deliveries.Conclusion: There is considerable room for improvement in availability and administration of prophylactic uterotonics. Understanding barriers to routine use may aid in developing multifaceted pre-service and in-service training interventions designed to improve routine intrapartum care. [ABSTRACT FROM AUTHOR]- Published
- 2016
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5. Innovative Uses of Condom Uterine Balloon Tamponade for Postpartum Hemorrhage in India and Tanzania.
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Makin, Jennifer, Suarez-Rebling, Daniela I., Varma Shivkumar, Poonam, Tarimo, Vincent, and Burke, Thomas F.
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MEDICAL balloons ,HEMORRHAGE treatment ,PREGNANCY complications ,PUERPERAL disorders ,MEDICAL care - Abstract
Background. Postpartum hemorrhage is the most common cause of maternal deaths worldwide, the majority of which occur in low-resource settings. Uterine balloon tamponade (UBT) is an effective method of addressing uncontrolled postpartum hemorrhage (PPH) from uterine atony; however, UBT devices are often not affordable. We report on three novel uses of an ultra-low-cost condom uterine balloon tamponade (ESM-UBT) device. Cases. ESM-UBT devices were used in innovative ways to arrest severe uncontrolled pregnancy-related hemorrhage among three women in India and Tanzania. The first had sustained deep vaginal lacerations, the second a cervical pregnancy, and the third a complete molar pregnancy. Conclusion. The ESM-UBT device may be useful for control of obstetric hemorrhage caused by complex vaginal tears as well as cervical and molar pregnancies. [ABSTRACT FROM AUTHOR]
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- 2018
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6. Reply.
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Conde-Agudelo, Agustin, Suarez, Sebastian, and Burke, Thomas F.
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RANDOMIZED controlled trials ,HEMORRHAGE ,SURGICAL hemostasis ,PUERPERAL disorders - Published
- 2020
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7. Provider experience of uterine balloon tamponade for the management of postpartum hemorrhage in Sierra Leone.
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Natarajan, Abirami, Kamara, Jennifer, Ahn, Roy, Nelson, Brett D., Eckardt, Melody J., Williams, Anne Marie, Kargbo, Samuel A., and Burke, Thomas F.
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UTERINE diseases , *HEMORRHAGE complications , *MATERNAL mortality , *PREGNANCY complications , *UTERINE hemorrhage , *HEMORRHAGE treatment , *MEDICAL education , *PUERPERAL disorders , *COMPARATIVE studies , *SURGICAL hemostasis , *INTERVIEWING , *RESEARCH methodology , *MEDICAL cooperation , *MEDICAL protocols , *RESEARCH , *DISEASE management , *QUALITATIVE research , *EVALUATION research , *THERAPEUTICS - Abstract
Objective: To understand healthcare providers' experience of incorporating uterine balloon tamponade (UBT) into the national postpartum hemorrhage (PPH) clinical pathway after UBT training.Methods: In a qualitative study, semi-structured interviews were undertaken with healthcare providers from 50 centers in Freetown, Sierra Leone, between May and June 2014. All eligible healthcare providers (undergone UBT training, actively conducted deliveries, and treated cases of PPH since UBT training) on duty at the time of center visit were interviewed.Results: Sixty-one providers at 47 facilities were interviewed. Bleeding was controlled in 28 (93%) of 30 cases of UBT device placement. Participants reported that UBT devices were easy to insert with only minor challenges, and enabled providers to manage most cases of uncontrolled PPH at their own facility and to refer others in a stable condition. Reported barriers to optimal UBT use included insufficient training and practical experience, and a scarcity of preassembled UBT devices. Facilitators of UBT use included widespread acceptance of UBT, comprehensive and enthusiastic training, and ready availability of UBT devices.Conclusion: UBT-used either as a primary endpoint or en route to obtaining advanced care-has been well accepted and integrated into the national PPH pathway by providers in health facilities in Freetown. [ABSTRACT FROM AUTHOR]- Published
- 2016
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8. Provider experiences with uterine balloon tamponade for uncontrolled postpartum hemorrhage in health facilities in Kenya.
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Natarajan, Abirami, Chavez, Jean, Ahn, Roy, Nelson, Brett D., Eckardt, Melody, Dulo, Liddy, Achieng, Emmaculate, Oguttu, Monica, Tester, Kristina, and Burke, Thomas F.
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PUERPERAL disorders , *HEMORRHAGE treatment , *CARDIAC tamponade , *MEDICAL balloons , *HEALTH facilities , *MATERNAL mortality , *FEASIBILITY studies , *MEDICAL education , *ATTITUDE (Psychology) , *DELIVERY (Obstetrics) , *MEDICAL personnel , *SURGICAL hemostasis , *QUALITATIVE research , *TREATMENT effectiveness , *EQUIPMENT & supplies , *THERAPEUTICS , *PSYCHOLOGY - Abstract
Objective: To understand provider perceptions and experiences following training in the use of a condom-catheter uterine balloon tamponade (UBT) as second-line treatment for uncontrolled postpartum hemorrhage (PPH) in health facilities in Kenya.Methods: As part of a qualitative study, interviews of facility-based providers who had managed PPH following comprehensive PPH training were conducted between February and April 2014. Facilities were purposively sampled to represent a range of experience with UBT, facility size, and geography. Interviews continued until thematic saturation was achieved. Interview transcripts were analyzed for themes.Results: Overall, 68 providers from 29 facilities were interviewed, of whom 31 reported experience with UBT placement (25 midwives, 2 clinical officers, 4 medical officers). Qualitative analysis revealed several major themes. Providers used UBT appropriately within the PPH algorithm, although the timing and clinical severity of patients varied. UBT was most commonly used when bleeding was unresponsive to uterotonics, hysterectomy was unavailable, and referral times long. Providers reported that bleeding was arrested following UBT use in all except one patient, who had a suspected coagulopathy. Most providers described UBT as technically easy to use, although three described initial balloon displacement.Conclusion: UBT has been readily accepted by providers at all levels of training and is being incorporated into the existing PPH management algorithm in Kenya. [ABSTRACT FROM AUTHOR]- Published
- 2015
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9. Use of uterine balloon tamponade for control of postpartum hemorrhage by community-based health providers in South Sudan.
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Nelson, Brett D., Stoklosa, Hanni, Ahn, Roy, Eckardt, Melody J., Walton, Emily K., and Burke, Thomas F.
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HEMORRHAGE , *PUERPERAL disorders , *CATHETERS , *CONDOMS , *SYRINGES , *POSTNATAL care - Abstract
Abstract: Objective: To determine whether use of uterine balloon tamponade (UBT) for management of uncontrolled postpartum hemorrhage (PPH) by community-based providers in a resource-limited setting could be feasible, effective, and safe. Methods: In rural South Sudan, community providers were trained and equipped with a simple UBT device consisting of a catheter, condom, and syringe. Snowball sampling identified cases of UBT use since training. Semi-structured interviews were conducted among community providers, referral facility providers, patients, and patient family members. Interview transcripts were analyzed using qualitative methods. Results: Thirteen cases were identified and 24 interviews related to community-based UBT use were conducted. Qualitative analysis revealed several major themes. Community providers applied UBT in appropriate clinical situations. UBT was effective for controlling PPH, even among severely ill patients. Referral was difficult and lengthy owing to the austere setting, but simple UBT appeared to mitigate these challenges. Communities had some initial fears, yet ultimately embraced UBT. Equipment and supplies were largely maintained. There was universal satisfaction with UBT among patients, family members, and providers. One death occurred among the 13 cases, although it was probably not attributable to PPH. Conclusion: Training and UBT device provision are simple, affordable, and effective for managing uncontrolled PPH in a resource-limited setting. [Copyright &y& Elsevier]
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- 2013
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10. Emergency hysterectomy for uncontrolled postpartum hemorrhage may be averted through uterine balloon tamponade in Kenya and Senegal.
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Pendleton, Anna Alaska, Natarajan, Abirami, Ahn, Roy, Nelson, Brett D., Eckardt, Melody J., and Burke, Thomas F.
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EMERGENCY contraceptives , *HYSTERECTOMY , *POSTPARTUM contraception , *UTERINE surgery , *MATERNAL mortality , *WOMEN , *HEMORRHAGE treatment , *PUERPERAL disorders , *COMPARATIVE studies , *SURGICAL hemostasis , *INTERVIEWING , *RESEARCH methodology , *MEDICAL cooperation , *MEDICAL emergencies , *RESEARCH , *EVALUATION research , *TREATMENT effectiveness , *THERAPEUTICS - Published
- 2016
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