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Amines alkylation with alcohols catalyzed by γ-Al2O3-supported nickel and copper nanoparticles under continuous process conditions at atmospheric hydrogen pressure and 180–220°С has led to the formation of alkylated products with selectivity up to 100%. [ABSTRACT FROM AUTHOR]

Using a modified deposition-precipitation method followed by sodium borohydride reduction of the precursor deposited on γ-Al2O3, copper-containing catalysts were obtained, which allow the continuous process of reductive alkylation of nitroarenes with alkanols at 200–220°C and atmospheric pressure of hydrogen with mono-N-alkylated products selectivity up to 100% and complete conversion of nitroarenes. [ABSTRACT FROM AUTHOR]

Alkylation of N,N-dialkylcarboxamides with 1,3-dehydroadamantane has been accomplished for the first time. The reaction involves the C-H bond in the α-position with respect to the carbonyl group and provides a convenient one-step preparation of substituted carboxylic acid amides containing an 1-adamantyl substituent and a pharmacophoric group in the amide moiety. [ABSTRACT FROM AUTHOR]

A synthetic route toward 1- N-heteryl-4-oxoadamantanes, intermediates in the synthesis of 1-heteryl-4-( R)-amino(acylamino)adamantanes used for treating type II diabetes and other diseases, was developed. Synthesis of 1- N-heteryl-4-oxoadamantanes was carried out by alkylation of saturated nitrogen-containing heterocycles with 1-bromo-4-oxoadamantane. [ABSTRACT FROM AUTHOR]

The article discusses the direct noncatalyzed alkylation with 1,3-dehydroadamantane of a series of polycyclic hydrocarbons such as acenaphthylene, tetralin, and fluorene. It results to an isolated adamantylation products purely with the methylene group and not with the aromatic ring for hydrocarbons. It adds that the alkylation with polycyclic hydrocarbon ensures the better selectivity of the monoaddition of the 1,3-dehydroadamantane than at the equimolar reagents ratio.