1. BSA imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres.
- Author
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Liu, Jiangquan, Ying, Xiaoguang, Wang, Hongxun, Li, Xiao, and Zhang, Weiying
- Subjects
MICROSPHERES ,POLYETHYLENE glycol ,CALCIUM alginate ,EPOXY compounds ,RING formation (Chemistry) ,ADDITION reactions - Abstract
ABSTRACT Polyethylene glycol grafted calcium alginate hydrogel microspheres are synthesized by ring-opening and addition reaction of epoxy chloropropane. FTIR,
13 C NMR, optical microscope, SEM, TG, and DSC are used for characterization. Swelling behaviors are studied and it is found that polyethylene glycol grafted calcium alginate microspheres are improved in anti-swelling properties. Protein-imprinted polyethylene glycol grafted calcium alginate hydrogel microspheres exhibit enhanced specific rebinding quantity (11.16 mg/g) and selective recognition properties (4.71 against BHb), towards target molecule in the presence of competing protein, compared with that of the unmodified samples (4.96 mg/g and 1.75, respectively). © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43617. [ABSTRACT FROM AUTHOR]- Published
- 2016
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