1. Glossodynia from Candida-associated lesions, burning mouth syndrome, or mixed causes.
- Author
-
Terai H and Shimahara M
- Subjects
- Adult, Aged, Aged, 80 and over, Antidepressive Agents therapeutic use, Antifungal Agents therapeutic use, Candidiasis drug therapy, Female, Glossalgia diagnosis, Glossalgia physiopathology, Humans, Male, Middle Aged, Pain Measurement, Treatment Outcome, Young Adult, Burning Mouth Syndrome complications, Candida pathogenicity, Candidiasis complications, Candidiasis pathology, Glossalgia etiology, Glossalgia microbiology
- Abstract
Objective: Candida-associated lesions (CALs) and burning mouth syndrome (BMS) may induce glossodynia without objective manifestations. We investigated patients with glossodynia to examine the relationship between CAL and BMS., Patients and Methods: A visual analog scale was used to divide 95 patients with glossodynia into three groups according to intensity of pain at rest and when eating. Group A was the functional pain group; group B was the nonfunctional pain group; and group C was a mixed pain group. Antifungal treatment was scheduled for patients with suspected Candida infection by clinical, mycological, or cytological criteria., Results: Culture tests and direct examination results indicated that group A had high Candida positivity (73.0% by culture and 59.5% by direct examination), and showed a good response to antifungal treatment (75.7%). Antifungal treatment was not useful in group B. This was supported by a low Candida infection rate, as determined by direct examination (3.1%). For group C, Candida positivity and antifungal treatment effectiveness were between groups A and B. Furthermore, six patients in group C showed complete remission of functional pain by antifungal treatment only. Favorable outcomes were obtained for 23 patients (10 in group B and 13 in group C), who received antidepressant treatment., Conclusion: These results suggested that glossodynia was Candida-associated in group A, and BMS-induced in group B, while group C contained patients with both CAL and BMS.
- Published
- 2010
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