39 results on '"Li, YongXin"'
Search Results
2. Cochlear implantation programming characteristics and outcomes of cochlear nerve deficiency.
- Author
-
Wei X, Lu S, Chen B, Chen J, Zhang L, Li Y, and Kong Y
- Subjects
- Humans, Cochlear Nerve abnormalities, Retrospective Studies, Cochlea surgery, Cochlear Implantation, Cochlear Implants
- Abstract
Purpose: Due to the specificity of cochlear implantation (CI) programming parameters and outcomes in cochlear nerve deficiency (CND) patients, this study aimed to investigate the correlation between programming parameters and outcomes and further compare the difference between normal and CND groups., Methods: Ninety (95 ears) CND patients (normal cochlea, 39; malformed cochlea, 56) and seventy-nine (81 ears) normal cochlea patients who underwent CI surgery with either Med-El or Cochlear devices were included. The programming parameters and outcomes evaluated by the questionnaires were collected and compared among the normal CND, malformed CND, and normal groups in the two device groups, and their correlation was analyzed., Results: In the CND group, a reduced stimulation rate, higher pulse width, and triphasic pulse were needed in some cases. The stimulus levels of the CND group were significantly higher than that of the normal group (p < 0.05), but the outcomes of the CND group were significantly worse than that of the normal group (p < 0.05), and the stimulus level was significantly correlated with the outcomes (p < 0.05). However, there was no difference between normal and malformed CND groups. The non-auditory response was observed in the CND group, especially the ones with malformations., Conclusion: The CI programming parameters of some CND patients need to be adjusted, and a slower stimulation rate and higher pulse width are required sometimes. CND patients need a higher stimulus level than normal patients but their outcomes are poorer. Non-auditory response should be noticed in CND patients during programming., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
3. Cochlear Implantation for Rudimentary Otocysts: Two Case Reports.
- Author
-
Lu S, Wei X, Kong Y, Yang B, Dhanasingh A, and Li Y
- Subjects
- Infant, Humans, Reactive Oxygen Species, Treatment Outcome, Hearing Loss, Bilateral surgery, Speech Intelligibility, Otolithic Membrane, Cochlear Implantation, Cochlear Implants, Deafness surgery, Speech Perception
- Abstract
Objective: Rudimentary otocyst (RO) is characterized by an otic capsule without an internal auditory canal, which is considered a contraindication to cochlear implantation (CI). In this study, we were the first to report two patients with ROs who underwent CI., Patient: Two patients (18 months old and 2 years old) presenting with bilateral congenital hearing loss were diagnosed with ROs., Intervention: CI was performed. The transmastoid slotted labyrinthotomy approach was used with customized MED-EL electrode arrays., Main Outcome Measures: Categorical auditory performance, infant-toddler meaningful auditory integration of sound, the speech intelligibility rating, and meaningful use of speech scale., Results: Both children could understand common phrases and had intelligible, connected speech 2 years after CI., Conclusion: With proper indication, surgical approach and postoperative training, a child with an RO may benefit from CI., Competing Interests: The authors disclose no conflicts of interest., (Copyright © 2023, Otology & Neurotology, Inc.)
- Published
- 2023
- Full Text
- View/download PDF
4. A 3-Year Follow-Up and Radiological Analysis of Cochlear Implantation Patients with Cochlear Nerve Deficiency and Modiolar Deficiency-Type Malformations.
- Author
-
Lu S, Wei X, Kong Y, Chen B, Chen J, Zhang L, Yang M, Xue S, Shi Y, Liu S, Xu T, Dong R, Chen X, and Li Y
- Subjects
- Infant, Humans, Retrospective Studies, Speech Intelligibility, Cochlear Nerve diagnostic imaging, Cochlear Nerve abnormalities, Treatment Outcome, Cochlear Implantation, Cochlear Implants, Speech Perception
- Abstract
Objective: Cochlear nerve deficiency (CND) is often combined with modiolar deficiency-type inner ear malformations, which cause variable cochlear implantation (CI) outcomes. We aimed to assess the postoperative development of auditory and speech perception in CND patients with modiolar deficiency-type malformations after 3 years of follow-up to determine the factors correlated with CI outcomes., Methods: Sixty-seven CND patients with modiolar deficiency-type malformations who underwent CI surgery were retrospectively reviewed. Modiolar deficiency-type malformations included common cavity (CC), cochlear hypoplasia (CH) (including CH-I and CH-II) and incomplete partition-I (IP-I). Categorical auditory performance (CAP) and the infant-toddler meaningful auditory integration scale (MAIS) were used to assess auditory ability. The speech intelligibility rating (SIR) and meaningful use of speech scale (MUSS) were used to assess the speech intelligibility of these CI patients. The CI outcomes were evaluated at 0, 12, 24 and 36 months after implant activation., Results: All patients demonstrated improvements in auditory ability and speech intelligibility after CI. There were no significant differences in CI outcomes at any time point according to the malformation type. The number of nerve bundles within the internal auditory canal (IAC) showed significant differences at 12, 24 and 36 months after CI ( p < 0.05). Patients with one nerve bundle had relatively poor CI outcomes., Conclusions: CND patients with modiolar deficiency-type malformations showed continuous improvement in auditory and speech abilities after CI. Compared with malformations, the number of nerve bundles should be given more attention when selecting the side for CI., Competing Interests: The authors disclose no conflicts of interest., (Copyright © 2022, Otology & Neurotology, Inc.)
- Published
- 2023
- Full Text
- View/download PDF
5. Cochlear Implant Facilitates the Use of Talker Sex and Spatial Cues to Segregate Competing Speech in Unilaterally Deaf Listeners.
- Author
-
Chen J, Shi Y, Kong Y, Chen B, Zhang L, Galvin JJ 3rd, Li Y, and Fu QJ
- Subjects
- Adult, Male, Humans, Female, Cues, Speech, Cochlear Implants, Speech Perception, Cochlear Implantation
- Abstract
Objectives: Talker sex and spatial cues can facilitate segregation of competing speech. However, the spectrotemporal degradation associated with cochlear implants (CIs) can limit the benefit of talker sex and spatial cues. Acoustic hearing in the nonimplanted ear can improve access to talker sex cues in CI users. However, it's unclear whether the CI can improve segregation of competing speech when maskers are symmetrically placed around the target (i.e., when spatial cues are available), compared with acoustic hearing alone. The aim of this study was to investigate whether a CI can improve segregation of competing speech by individuals with unilateral hearing loss., Design: Speech recognition thresholds (SRTs) for competing speech were measured in 16 normal-hearing (NH) adults and 16 unilaterally deaf CI users. All participants were native speakers of Mandarin Chinese. CI users were divided into two groups according to thresholds in the nonimplanted ear: (1) single-sided deaf (SSD); pure-tone thresholds <25 dB HL at all audiometric frequencies, and (2) Asymmetric hearing loss (AHL; one or more thresholds > 25 dB HL). SRTs were measured for target sentences produced by a male talker in the presence of two masker talkers (different male or female talkers). The target sentence was always presented via loudspeaker directly in front of the listener (0°), and the maskers were either colocated with the target (0°) or spatially separated from the target at ±90°. Three segregation cue conditions were tested to measure masking release (MR) relative to the baseline condition: (1) Talker sex, (2) Spatial, and (3) Talker sex + Spatial. For CI users, SRTs were measured with the CI on or off., Results: Binaural MR was significantly better for the NH group than for the AHL or SSD groups ( P < 0.001 in all cases). For the NH group, mean MR was largest with the Talker sex + spatial cues (18.8 dB) and smallest for the Talker sex cues (10.7 dB). In contrast, mean MR for the SSD group was largest with the Talker sex + spatial cues (14.7 dB), and smallest with the Spatial cues (4.8 dB). For the AHL group, mean MR was largest with the Talker sex + spatial cues (7.8 dB) and smallest with the Talker sex (4.8 dB) and the Spatial cues (4.8 dB). MR was significantly better with the CI on than off for both the AHL ( P = 0.014) and SSD groups ( P < 0.001). Across all unilaterally deaf CI users, monaural (acoustic ear alone) and binaural MR were significantly correlated with unaided pure-tone average thresholds in the nonimplanted ear for the Talker sex and Talker sex + spatial conditions ( P < 0.001 in both cases) but not for the Spatial condition., Conclusion: Although the CI benefitted unilaterally deaf listeners' segregation of competing speech, MR was much poorer than that observed in NH listeners. Different from previous findings with steady noise maskers, the CI benefit for segregation of competing speech from a different talker sex was greater in the SSD group than in the AHL group., Competing Interests: Q.F. has a financial interest at Nurotron Biotechnology Co. Ltd., a medical device company that designs, develops, and markets CI systems. The remaining authors have no conflicts of interest to disclose., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
6. Cochlear implantation for post-meningitis deafness with cochlear ossification: diagnosis and surgical strategy.
- Author
-
Zhang N, Dong R, Zheng J, Zhao Y, Li Y, Chen X, and Zhao S
- Subjects
- Humans, Osteogenesis, Retrospective Studies, Cochlear Implantation methods, Cochlear Implants adverse effects, Deafness surgery, Hearing Loss, Sensorineural diagnosis, Hearing Loss, Sensorineural etiology, Hearing Loss, Sensorineural surgery, Meningitis complications, Meningitis diagnostic imaging, Ossification, Heterotopic diagnosis, Ossification, Heterotopic diagnostic imaging
- Abstract
Background: Cochlear ossification (CO) after meningitis can cause profound sensorineural hearing loss (SNHL). Cochlear implantation (CI) is the ideal treatment strategy for CO., Aims: To explore the strategy for CI in patients with CO after meningitis., Materials and Methods: In this retrospective study, the medical records of patients diagnosed with profound SNHL due to CO after meningitis and who underwent CI in our department between September 2010 and September 2021 were collected and reviewed. Their imaging and surgical findings were analyzed., Results: The data of 26 patients with unilateral CI were reviewed. All patients underwent preoperative temporal high-resolution computed tomography (HRCT) and 22 patients magnetic resonance imaging (MRI). The sensitivity of HRCT was 61.5% (10/26), whereas that of MRI was 81.8% (18/22). Combined HRCT and MRI achieved a detection rate of 92.3% (24/26). Twenty-two and four patients underwent complete and partial electrode implantations, respectively., Conclusions and Significance: Preoperative temporal bone HRCT and MRI are essential for determining whether a patient is suitable for CI and surgical planning. A false-negative diagnosis is possible when diagnosing CO, but combined HRCT and MRI can improve the positive rate of preoperative diagnosis of CO post meningitis. Early CI is recommended.
- Published
- 2022
- Full Text
- View/download PDF
7. Worldwide Variation in Cochlear Implant Candidacy.
- Author
-
Van de Heyning P, Gavilán J, Godey B, Hagen R, Hagr A, Kameswaran M, Li Y, Manoj M, Mlynski R, O'Driscoll M, Pillsbury H, Raine CH, Rajan G, Schmutzhard J, and Staecker H
- Subjects
- Hearing, Hearing Tests, Humans, Treatment Outcome, Cochlear Implantation, Cochlear Implants, Hearing Loss surgery, Speech Perception
- Abstract
Background: The aim of this study was to find out how candidacy criteria have evolved differently across the globe., Methods: Candidacy criteria and outcome measurements applied in 19 HEARRING clinics were analyzed., Results: Candidacy criteria vary between clinics. Overall, both bilateral implantation and cochlear implantation in patients with single-sided deafness are becoming more frequent., Conclusion: Standardized outcome measurement instruments need to be applied to provide access to the hearing world to all patients with hearing loss who would benefit from cochlear implantation.
- Published
- 2022
- Full Text
- View/download PDF
8. A retrospective review of cochlear implant revision surgery: a 24-year experience in China.
- Author
-
Chen J, Chen B, Shi Y, and Li Y
- Subjects
- Adult, Child, China epidemiology, Cohort Studies, Humans, Prosthesis Failure, Reoperation, Retrospective Studies, Cochlear Implantation adverse effects, Cochlear Implants
- Abstract
Purpose: We aimed to analyse the reasons behind the need for cochlear implant revision surgeries, as well as the rate at which they occur, to reduce the revision surgery rate for non-device failures. We also aimed to elucidate the cumulative survival and device survival rates in different age groups., Methods: This retrospective single cohort study reviewed 4563 cochlear implant surgeries and 119 revision surgeries performed at a tertiary referral hospital in China between 1996 and 2019. Kaplan-Meier curves were used to calculate the cumulative survival and device survival rates., Results: The revision surgery rate was 2.61%. The reasons for revision included device (73.1%) and non-device (26.9%) failures. The most common reasons were hard device (47.1%) and non-device failure (28.6%). The 10- and 20-year cumulative survival rates were 96.8% and 96.7%, respectively. Younger children were more likely to undergo a second surgery., Conclusion: This study is the longest study about revision surgery in China. Cochlear implantation is a reliable treatment. It has a low complication rate in patients with sensorineural hearing loss. Children have a higher revision rate than adults. Doctors should be aware of each complication and perform the appropriate procedure., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
- Full Text
- View/download PDF
9. Severe and persistent facial nerve stimulation after cochlear implantation in a patient with cochlear-facial dehiscence: a case report.
- Author
-
Chen J, Chen B, Zhang L, and Li Y
- Subjects
- Cochlea surgery, Facial Nerve diagnostic imaging, Facial Nerve surgery, Humans, Cochlear Implantation, Cochlear Implants, Otosclerosis surgery
- Abstract
Generally, cochlear implants (CIs) are effective in helping patients improve their hearing performance; however, some patients have poor hearing performance owing to facial nerve stimulation (FNS), which is often associated with cochlear anomalies. We report a case with a normal cochlea and severe and persistent FNS owing to cochlear-facial dehiscence (CFD) that affected the CI outcomes. Preoperatively, a careful review of the computed tomography images before CI surgery is necessary not only for patients with otosclerosis and inner ear malformations but also for patients with normal cochlear structures because facial nerve anomalies could be present.
- Published
- 2021
- Full Text
- View/download PDF
10. Masking Effects in the Perception of Multiple Simultaneous Talkers in Normal-Hearing and Cochlear Implant Listeners.
- Author
-
Chen B, Shi Y, Zhang L, Sun Z, Li Y, Gopen Q, and Fu QJ
- Subjects
- Humans, Perceptual Masking, Cochlear Implantation, Cochlear Implants, Speech Perception
- Published
- 2020
- Full Text
- View/download PDF
11. Cochlear implants for patients with inner ear malformation: Experience in a cohort of 877 surgeries.
- Author
-
Shi Y, Li Y, Gong Y, Chen B, and Chen J
- Subjects
- Child, Child, Preschool, Female, Humans, Intraoperative Complications, Male, Speech Intelligibility, Cochlear Implantation methods, Cochlear Implants, Ear, Inner abnormalities
- Abstract
Objective: To analyse clinical information from a cohort of 877 cochlear implant (CI) surgeries performed in patients with inner ear malformations and report our experience with this procedure., Methods: Clinical information on patients with inner ear malformation who underwent CI surgery in our department from January 2010 to April 2017 was analysed., Results: Seven hundred and fifty-four CI surgeries (86.0%) were uneventful but cerebrospinal fluid gusher occurred during surgery in 118 cases (13.5%). Not including the patients lost to follow-up, postoperative Categories of Auditory Performance (CAP) and Speech Intelligibility Rating (SIR) scores were collected from 13 patients with common cavity deformity, 38 with IP-I, 11 with hypoplasia, 13 with IP-III, 285 with IP-II and 43 with cochlear nerve deficiency. The mean CAP scores were 2.55, 3.39, 3.45, 3.77, 3.98, 2.95 and 2.90, and the mean SIR scores were 1.54, 3.68, 3.72, 3.54, 3.80, 2.31 and 2.32. Patients with common cavity deformity who underwent surgery using the traditional facial recess approach or transmastoid slotted labyrinthotomy approach had significantly better post-activation scores on the CAP, SIR and Meaningful Auditory Integration Scale/Infant-Toddler Meaningful Auditory Integration Scale, with no significant differences between the two approaches., Conclusion: The traditional facial recess approach can be successful, and several approaches may be used for electrode insertion and gusher control in patients with a severe deformity, particularly common cavity deformity and IP-III. A gusher was the most common intraoperative finding and occurred most often in patients with IP-III. Careful consideration of the type of electrode used is important., (© 2019 John Wiley & Sons Ltd.)
- Published
- 2019
- Full Text
- View/download PDF
12. Intelligibility of naturally produced and synthesized Mandarin speech by cochlear implant listeners.
- Author
-
Shi Y, Chen J, Gong Y, Chen B, Li Y, Galvin JJ 3rd, and Fu QJ
- Subjects
- Adolescent, Adult, Female, Humans, Male, Middle Aged, Young Adult, Auditory Perception physiology, Cochlear Implantation methods, Cochlear Implants, Communication Aids for Disabled, Persons With Hearing Impairments, Speech Intelligibility physiology
- Abstract
Mandarin is a tonal language, and it is important to preserve lexical tone information in synthesized speech. With natural speech, Chinese cochlear implant (CI) users have difficulty perceiving voice pitch cues important for lexical tone perception; it is unclear whether this difficulty persists in Mandarin synthesized speech. In this study, intelligibility of naturally produced and synthesized Mandarin speech was measured in Chinese CI listeners; intelligibility was also measured in a control group of normal-hearing (NH) listeners. Five synthesized voices were selected to represent different talker genders (male, female, child), speaking rates (normal, slow), and speaking styles (emotional, accent). The data showed that while modern Mandarin text-to-speech (TTS) systems can provide perfect speech intelligibility for NH listeners, overall intelligibility was much poorer for CI than for NH listeners. CI performance was significantly poorer with synthesized speech than with natural speech (p < 0.001). CI listeners were highly sensitive to the "extra-atypical" synthesized emotional and accented speech. Performance with each of the synthesized speech types was significantly correlated with performance with natural speech in CI users (p < 0.01 in all cases). While modern TTS systems offer educational and communication benefits to CI users and hearing-impaired individuals, the selection of synthesized voices should be carefully considered in education applications of TTS for hearing-impaired individuals, especially CI children, since poor intelligibility performance may affect language learning.
- Published
- 2018
- Full Text
- View/download PDF
13. Predicting Auditory Outcomes From Radiological Imaging in Cochlear Implant Patients With Cochlear Nerve Deficiency.
- Author
-
Wei X, Li Y, Chen B, Gong Y, Fu QJ, Liu T, Cui D, Su Q, and Shi Y
- Subjects
- Child, Preschool, Cochlear Implantation, Cochlear Nerve surgery, Female, Humans, Imaging, Three-Dimensional, Magnetic Resonance Imaging methods, Male, Prognosis, Retrospective Studies, Tomography, X-Ray Computed, Cochlear Implants, Cochlear Nerve diagnostic imaging
- Abstract
Objective: To compare imaging and outcome data in cochlear implant (CI) patients with and without cochlear nerve deficiency (CND)., Study Design: Retrospective study comparing presurgical imaging (via high-resolution computed tomography and three-dimensional magnetic resonance imaging) to postsurgical auditory outcomes in CI patients with and without CND., Patients: Forty-three CI patients with CND diagnosed according to preoperative imaging were included in the CND group. A control group (non-CND; n = 43) was matched to the CND group in terms of age at implantation, CI device type, preoperative hearing threshold, and sex., Results: Across all subjects, internal auditory canal (IAC) diameter, cochlear nerve canal (CNC) diameter, and the number of nerve bundles were significantly correlated with all auditory outcome measures (p < 0.0125 in all cases). Across CND subjects, CNC diameter was significantly correlated with SIR, MUSS, and MAIS-IT/ MAIS scores (p < 0.0125 in all cases). Auditory outcomes were significantly poorer for CND patients with one rather than two nerve bundles. Across non-CND subjects, CNC diameter was significantly correlated only with SIR scores (p < 0.0125). IAC diameter, CNC diameter, and the number of nerve bundles were significantly smaller, and auditory outcomes were significantly poorer for the CND group than for the non-CND group (p < 0.05 in all cases). Results were similar when data only from patients ≤ 5 years old (n = 31) were analyzed., Conclusions: CNC diameter and the number of nerve bundles can significantly predict auditory outcomes for CI patients with CND. The results suggest that presurgical imaging may be useful in predicting CI outcomes for congenitally deaf patients.
- Published
- 2017
- Full Text
- View/download PDF
14. Validation of list equivalency for Mandarin speech materials to use with cochlear implant listeners.
- Author
-
Li Y, Wang S, Su Q, Galvin JJ, and Fu QJ
- Subjects
- Acoustic Stimulation, Adolescent, Adult, Age Factors, Child, China, Cues, Electric Stimulation, Female, Hearing Loss diagnosis, Hearing Loss physiopathology, Hearing Loss psychology, Humans, Male, Middle Aged, Persons With Hearing Impairments psychology, Predictive Value of Tests, Reproducibility of Results, Speech Acoustics, Young Adult, Audiometry, Speech methods, Cochlear Implantation instrumentation, Cochlear Implants, Hearing, Hearing Loss rehabilitation, Persons With Hearing Impairments rehabilitation, Phonetics, Speech Perception
- Abstract
Objectives: Speech materials validated with normal-hearing listeners may not be appropriate for clinical assessment of cochlear implant (CI) users. The aim of this study was to validate list equivalency of the Mandarin Speech Perception (MSP) sentences, disyllables, and monosyllables in Mandarin-speaking CI patients., Design: Recognition of MSP sentences, disyllables, and monosyllables each were measured for all 10 lists., Study Sample: 67 adult and 32 pediatric Mandarin-speaking CI users., Results: There was no significant difference between adult and pediatric subject groups for all test materials. Significant differences were observed among lists within each test. After removing one or two lists within each test, no significant differences were observed among the remaining lists. While there was equal variance among lists within a given test, the variance was larger for children than for adults, and increased from monosyllables to disyllables to sentences., Conclusions: Some adjustment to test lists previously validated with CI simulations was needed to create perceptually equivalent lists for real CI users, suggesting that test materials should be validated in the targeted population. Differences in mean scores and variance across test materials suggest that CI users may differ in their ability to make use of contextual cues available in sentences and disyllables.
- Published
- 2017
- Full Text
- View/download PDF
15. Electrically evoked compound action potentials are different depending on the site of cochlear stimulation.
- Author
-
van de Heyning P, Arauz SL, Atlas M, Baumgartner WD, Caversaccio M, Chester-Browne R, Estienne P, Gavilan J, Godey B, Gstöttner W, Han D, Hagen R, Kompis M, Kuzovkov V, Lassaletta L, Lefevre F, Li Y, Müller J, Parnes L, Kleine Punte A, Raine C, Rajan G, Rivas A, Rivas JA, Royle N, Sprinzl G, Stephan K, Walkowiak A, Yanov Y, Zimmermann K, Zorowka P, and Skarzynski H
- Subjects
- Adult, Cochlea physiopathology, Cochlear Implantation methods, Female, Hearing Loss, Sensorineural surgery, Humans, Male, Prospective Studies, Treatment Outcome, Action Potentials, Cochlear Implants, Electric Stimulation methods, Evoked Potentials, Auditory, Hearing Loss, Sensorineural physiopathology
- Abstract
One of the many parameters that can affect cochlear implant (CI) users' performance is the site of presentation of electrical stimulation, from the CI, to the auditory nerve. Evoked compound action potential (ECAP) measurements are commonly used to verify nerve function by stimulating one electrode contact in the cochlea and recording the resulting action potentials on the other contacts of the electrode array. The present study aimed to determine if the ECAP amplitude differs between the apical, middle, and basal region of the cochlea, if double peak potentials were more likely in the apex than the basal region of the cochlea, and if there were differences in the ECAP threshold and recovery function across the cochlea. ECAP measurements were performed in the apical, middle, and basal region of the cochlea at fixed sites of stimulation with varying recording electrodes. One hundred and forty one adult subjects with severe to profound sensorineural hearing loss fitted with a Standard or FLEX
SOFT electrode were included in this study. ECAP responses were captured using MAESTRO System Software (MED-EL). The ECAP amplitude, threshold, and slope were determined using amplitude growth sequences. The 50% recovery rate was assessed using independent single sequences that have two stimulation pulses (a masker and a probe pulse) separated by a variable inter-pulse interval. For all recordings, ECAP peaks were annotated semi-automatically. ECAP amplitudes were greater upon stimulation of the apical region compared to the basal region of the cochlea. ECAP slopes were steeper in the apical region compared to the basal region of the cochlea and ECAP thresholds were lower in the middle region compared to the basal region of the cochlea. The incidence of double peaks was greater upon stimulation of the apical region compared to the basal region of the cochlea. This data indicates that the site and intensity of cochlear stimulation affect ECAP properties.- Published
- 2016
- Full Text
- View/download PDF
16. Effects of Within-Talker Variability on Speech Intelligibility in Mandarin-Speaking Adult and Pediatric Cochlear Implant Patients.
- Author
-
Su Q, Galvin JJ, Zhang G, Li Y, and Fu QJ
- Subjects
- Adult, Child, Cochlear Implantation, Humans, Language, Speech Perception, Cochlear Implants, Speech Intelligibility
- Abstract
Cochlear implant (CI) speech performance is typically evaluated using well-enunciated speech produced at a normal rate by a single talker. CI users often have greater difficulty with variations in speech production encountered in everyday listening. Within a single talker, speaking rate, amplitude, duration, and voice pitch information may be quite variable, depending on the production context. The coarse spectral resolution afforded by the CI limits perception of voice pitch, which is an important cue for speech prosody and for tonal languages such as Mandarin Chinese. In this study, sentence recognition from the Mandarin speech perception database was measured in adult and pediatric Mandarin-speaking CI listeners for a variety of speaking styles: voiced speech produced at slow, normal, and fast speaking rates; whispered speech; voiced emotional speech; and voiced shouted speech. Recognition of Mandarin Hearing in Noise Test sentences was also measured. Results showed that performance was significantly poorer with whispered speech relative to the other speaking styles and that performance was significantly better with slow speech than with fast or emotional speech. Results also showed that adult and pediatric performance was significantly poorer with Mandarin Hearing in Noise Test than with Mandarin speech perception sentences at the normal rate. The results suggest that adult and pediatric Mandarin-speaking CI patients are highly susceptible to whispered speech, due to the lack of lexically important voice pitch cues and perhaps other qualities associated with whispered speech. The results also suggest that test materials may contribute to differences in performance observed between adult and pediatric CI users., (© The Author(s) 2016.)
- Published
- 2016
- Full Text
- View/download PDF
17. Mandarin speech perception in combined electric and acoustic stimulation.
- Author
-
Li Y, Zhang G, Galvin JJ 3rd, and Fu QJ
- Subjects
- Acoustic Stimulation, Adolescent, Adult, Auditory Threshold, Electric Stimulation, Female, Humans, Male, Noise, Cochlear Implants, Hearing Aids, Language, Speech Perception physiology
- Abstract
For deaf individuals with residual low-frequency acoustic hearing, combined use of a cochlear implant (CI) and hearing aid (HA) typically provides better speech understanding than with either device alone. Because of coarse spectral resolution, CIs do not provide fundamental frequency (F0) information that contributes to understanding of tonal languages such as Mandarin Chinese. The HA can provide good representation of F0 and, depending on the range of aided acoustic hearing, first and second formant (F1 and F2) information. In this study, Mandarin tone, vowel, and consonant recognition in quiet and noise was measured in 12 adult Mandarin-speaking bimodal listeners with the CI-only and with the CI+HA. Tone recognition was significantly better with the CI+HA in noise, but not in quiet. Vowel recognition was significantly better with the CI+HA in quiet, but not in noise. There was no significant difference in consonant recognition between the CI-only and the CI+HA in quiet or in noise. There was a wide range in bimodal benefit, with improvements often greater than 20 percentage points in some tests and conditions. The bimodal benefit was compared to CI subjects' HA-aided pure-tone average (PTA) thresholds between 250 and 2000 Hz; subjects were divided into two groups: "better" PTA (<50 dB HL) or "poorer" PTA (>50 dB HL). The bimodal benefit differed significantly between groups only for consonant recognition. The bimodal benefit for tone recognition in quiet was significantly correlated with CI experience, suggesting that bimodal CI users learn to better combine low-frequency spectro-temporal information from acoustic hearing with temporal envelope information from electric hearing. Given the small number of subjects in this study (n = 12), further research with Chinese bimodal listeners may provide more information regarding the contribution of acoustic and electric hearing to tonal language perception.
- Published
- 2014
- Full Text
- View/download PDF
18. Cochlear implants with fine structure processing improve speech and tone perception in Mandarin-speaking adults.
- Author
-
Chen X, Liu B, Liu S, Mo L, Li Y, Kong Y, Zheng J, Li Y, Gong S, and Han D
- Subjects
- Adult, Auditory Perception physiology, China, Deafness diagnosis, Female, Follow-Up Studies, Humans, Language, Male, Middle Aged, Prospective Studies, Prosthesis Design, Sampling Studies, Speech Therapy methods, Time Factors, Treatment Outcome, Young Adult, Cochlear Implantation methods, Cochlear Implants, Deafness ethnology, Deafness surgery, Pitch Perception physiology, Speech Perception physiology
- Abstract
Conclusion: This study indicates that Mandarin-speaking subjects acquire significant benefit from a cochlear implant (CI) and audio processor with the fine structure processing (FSP) coding strategy. It can take adult Mandarin CI users time to become accustomed to their CI and appreciate the benefits., Objectives: This study aimed to determine speech perception outcomes in Mandarin-speaking adults who received the FSP coding strategy., Methods: This was a prospective study. Ten adults who were implanted unilaterally with a PULSARCI(100), and received an OPUS 1 or OPUS 2 speech processor, were included in this study. The mean age at implantation was 31.1 years. We determined the benefit to postlingually deafened Mandarin-speaking adults with a severe to profound hearing loss using the tests: monosyllables in quiet, sentences in quiet and the Mandarin Hearing in Noise Test (MHINT). Tone perception was evaluated using a tone perception test. A visual analog scale (VAS) was used to score sound quality and ease of listening., Results: The results showed a significant improvement between first fitting and 6 months in all speech tests and in tone perception. The VAS scores showed a significant improvement over 6 months in sound quality and an immediate benefit in ease of listening.
- Published
- 2013
- Full Text
- View/download PDF
19. Speech recognition and acoustic features in combined electric and acoustic stimulation.
- Author
-
Yoon YS, Li Y, and Fu QJ
- Subjects
- Acoustic Stimulation, Adult, Aged, Analysis of Variance, Audiometry, Speech, Differential Threshold, Electric Stimulation instrumentation, Female, Humans, Male, Middle Aged, Sound Spectrography, Speech Discrimination Tests, Cochlear Implants, Hearing Aids, Hearing Loss rehabilitation, Signal-To-Noise Ratio, Speech Perception
- Abstract
Purpose: In this study, the authors aimed to identify speech information processed by a hearing aid (HA) that is additive to information processed by a cochlear implant (CI) as a function of signal-to-noise ratio (SNR)., Method: Speech recognition was measured with CI alone, HA alone, and CI + HA. Ten participants were separated into 2 groups; good (aided pure-tone average [PTA] < 55 dB) and poor (aided PTA ≥ 55 dB) at audiometric frequencies ≤ 1 kHz in HA., Results: Results showed that the good-aided PTA group derived a clear bimodal benefit (performance difference between CI + HA and CI alone) for vowel and sentence recognition in noise, whereas the poor-aided PTA group received little benefit across speech tests and SNRs. Results also showed that a better aided PTA helped in processing cues embedded in both low and high frequencies; none of these cues was significantly perceived by the poor-aided PTA group., Conclusions: The aided PTA is an important indicator for bimodal advantage in speech perception. The lack of bimodal benefits in the poor group may be attributed to the nonoptimal HA fitting. Bimodal listening provides a synergistic effect for cues in both low- and high-frequency components in speech.
- Published
- 2012
- Full Text
- View/download PDF
20. The relationship between binaural benefit and difference in unilateral speech recognition performance for bilateral cochlear implant users.
- Author
-
Yoon YS, Li Y, Kang HY, and Fu QJ
- Subjects
- Acoustic Stimulation, Aged, Aged, 80 and over, Female, Functional Laterality, Hearing Loss psychology, Humans, Male, Middle Aged, Noise adverse effects, Perceptual Masking, Persons With Hearing Impairments psychology, Prosthesis Design, Speech Discrimination Tests, Speech Reception Threshold Test, Young Adult, Cochlear Implantation instrumentation, Cochlear Implants, Correction of Hearing Impairment psychology, Hearing Loss rehabilitation, Persons With Hearing Impairments rehabilitation, Recognition, Psychology, Speech Acoustics, Speech Intelligibility, Speech Perception
- Abstract
Objective: The full benefit of bilateral cochlear implants may depend on the unilateral performance with each device, the speech materials, processing ability of the user, and/or the listening environment. In this study, bilateral and unilateral speech performances were evaluated in terms of recognition of phonemes and sentences presented in quiet or in noise., Design: Speech recognition was measured for unilateral left, unilateral right, and bilateral listening conditions; speech and noise were presented at 0° azimuth. The 'binaural benefit' was defined as the difference between bilateral performance and unilateral performance with the better ear., Study Sample: Nine adults with bilateral cochlear implants participated., Results: On average, results showed a greater binaural benefit in noise than in quiet for all speech tests. More importantly, the binaural benefit was greater when unilateral performance was similar across ears. As the difference in unilateral performance between ears increased, the binaural advantage decreased; this functional relationship was observed across the different speech materials and noise levels even though there was substantial intra- and inter-subject variability., Conclusions: The results indicate that subjects who show symmetry in speech recognition performance between implanted ears in general show a large binaural benefit.
- Published
- 2011
- Full Text
- View/download PDF
21. Effects of speaking style on speech intelligibility for Mandarin-speaking cochlear implant users.
- Author
-
Li Y, Zhang G, Kang HY, Liu S, Han D, and Fu QJ
- Subjects
- Acoustic Stimulation, Adult, Analysis of Variance, Audiometry, Speech, Comprehension, Female, Humans, Linear Models, Loudness Perception, Male, Middle Aged, Persons With Hearing Impairments psychology, Prosthesis Design, Random Allocation, Recognition, Psychology, Time Factors, Young Adult, Cochlear Implantation instrumentation, Cochlear Implants, Correction of Hearing Impairment psychology, Language, Persons With Hearing Impairments rehabilitation, Speech Acoustics, Speech Intelligibility, Speech Perception
- Abstract
Cochlear implant (CI) users' speech understanding may be influenced by different speaking styles. In this study, speech recognition was measured in Mandarin-speaking CI and normal-hearing (NH) subjects for sentences produced according to four styles: slow, normal, fast, and whispered. CI subjects were tested using their clinical processors; NH subjects were tested while listening to a four-channel CI simulation. Performance gradually worsened with increasing speaking rate and was much poorer with whispered speech. CI performance was generally similar to NH performance with the four-channel simulation. Results suggest that some speaking styles, especially whispering, may negatively affect Mandarin-speaking CI users' speech understanding., (© 2011 Acoustical Society of America)
- Published
- 2011
- Full Text
- View/download PDF
22. Vocal singing by prelingually-deafened children with cochlear implants.
- Author
-
Xu L, Zhou N, Chen X, Li Y, Schultz HM, Zhao X, and Han D
- Subjects
- Child, Child, Preschool, Deafness psychology, Female, Humans, Male, Speech, Speech Acoustics, Cochlear Implants, Deafness physiopathology, Deafness therapy, Music, Voice physiology
- Abstract
The coarse pitch information in cochlear implants might hinder the development of singing in prelingually-deafened pediatric users. In the present study, seven prelingually-deafened children with cochlear implants (5.4-12.3 years old) sang one song that was the most familiar to him or her. The control group consisted of 14 normal-hearing children (4.1-8.0 years old). The fundamental frequencies (F0) of each note in the recorded songs were extracted. The following five metrics were computed based on the reference music scores: (1) F0 contour direction of the adjacent notes, (2) F0 compression ratio of the entire song, (3) mean deviation of the normalized F0 across the notes, (4) mean deviation of the pitch intervals, and (5) standard deviation of the note duration differences. Children with cochlear implants showed significantly poorer performance in the pitch-based assessments than the normal-hearing children. No significant differences were seen between the two groups in the rhythm-based measure. Prelingually-deafened children with cochlear implants have significant deficits in singing due to their inability to manipulate pitch in the correct directions and to produce accurate pitch height. Future studies with a large sample size are warranted in order to account for the large variability in singing performance.
- Published
- 2009
- Full Text
- View/download PDF
23. Tone production of Mandarin Chinese speaking children with cochlear implants.
- Author
-
Han D, Zhou N, Li Y, Chen X, Zhao X, and Xu L
- Subjects
- Adult, Age Factors, Case-Control Studies, Child, Child, Preschool, China, Cochlear Implantation, Deafness surgery, Female, Humans, Infant, Male, Speech Perception physiology, Speech Production Measurement, Cochlear Implants, Speech Intelligibility physiology
- Abstract
Objective: The purpose of the present study was to investigate tone production performance of native Mandarin Chinese speaking children with cochlear implants and to evaluate the effects of age at implantation and duration of implant use on tone production in those children., Methods: Fourteen prelingually deaf children who had received cochlear implantation and 14 age-matched normal-hearing children participated in the study. Both groups were of native Mandarin Chinese speaking children. One hundred and sixty tone tokens were recorded from each of the children. The total of 4480 tokens (160x28) were then used in the tone perception tests in which seven normal-hearing native Mandarin Chinese speaking adults participated., Results: The tone production of the cochlear implant children showed tremendous individual variability. The group mean performance was 48.4% correct, statistically significantly lower than the group mean performance of 78.0% correct in the normal-hearing controls. The tone confusion matrix analysis revealed that the production of Mandarin tone 2 (the rising tone) was most severely impaired in the cochlear implant children, followed by tone 3 (the low and dipping tone) and tone 4 (the falling tone). The most frequently perceived tone irrespective of the target tone was tone 1 (the high level tone). The tone production performance was negatively correlated with the age at implantation and positively correlated with the duration of implant use., Conclusions: There is a remarkable deficit in tone production in a majority of native tone language speaking, prelingually deaf children who have received cochlear implants. While an increased duration of implant use might facilitate tone production, the age at implantation appears to have a negative effect on tone production in cochlear implant children. Therefore, early implantation might be beneficial to tone production in prelingually deaf children whose native language is a tone language.
- Published
- 2007
- Full Text
- View/download PDF
24. Machine learning-based prediction of the outcomes of cochlear implantation in patients with inner ear malformation.
- Author
-
Weng, Jiuling, Xue, Shujin, Wei, Xingmei, Lu, Simeng, Xie, Jin, Kong, Ying, Shen, Mengya, Chen, Biao, Chen, Jingyuan, Zou, Xinyue, Zhang, Xinyi, Gao, Zhencheng, Liu, Ping, Shi, Ying, Cui, Danmo, Li, Yongxin, and Wang, Haihui
- Subjects
INNER ear physiology ,COCHLEAR implants ,K-nearest neighbor classification ,INTELLIGIBILITY of speech ,FEATURE selection ,IMAGE reconstruction - Abstract
Objective: The objectives of this study are twofold: first, to visualize the structure of malformed cochleae through image reconstruction; and second, to develop a predictive model for postoperative outcomes of cochlear implantation (CI) in patients diagnosed with cochlear hypoplasia (CH) and incomplete partition (IP) malformation. Methods: The clinical data from patients diagnosed with cochlear hypoplasia (CH) and incomplete partition (IP) malformation who underwent cochlear implantation (CI) at Beijing Tongren Hospital between January 2016 and August 2020 were collected. Radiological features were analyzed through 3D segmentation of the cochlea. Postoperative auditory speech rehabilitation outcomes were evaluated using the Categories of Auditory Performance (CAP) and the Speech Intelligibility Rating (SIR). This study aimed to investigate the relationship between cochlear parameters and postoperative outcomes. Additionally, a predictive model for postoperative outcomes was developed using the K-nearest neighbors (KNN) algorithm. Results: In our study, we conducted feature selection by using patients' imaging and audiological attributes. This process involved methods such as the removal of missing values, correlation analysis, and chi-square tests. The findings indicated that two specific features, cochlear volume (V) and cochlear canal length (CDL), significantly contributed to predicting the outcomes of hearing and speech rehabilitation for patients with inner ear malformations. In terms of hearing rehabilitation, the KNN classification achieved an accuracy of 93.3%. Likewise, for speech rehabilitation, the KNN classification demonstrated an accuracy of 86.7%. Conclusion: The measurements obtained from the 3D reconstruction model hold significant clinical relevance. Despite the considerable variability in cochlear morphology across individuals, radiological features remain effective in predicting cochlear implantation (CI) prognosis for patients with inner ear malformations. The utilization of 3D segmentation techniques and the developed predictive model can assist surgeons in conducting preoperative cochlear structural measurements for patients with inner ear malformations. This, in turn, can offer a more informed perspective on the anticipated outcomes of cochlear implantation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
25. Susceptibility to Steady Noise Largely Explains Susceptibility to Dynamic Maskers in Cochlear Implant Users, but not in Normal-Hearing Listeners.
- Author
-
Chen, Biao, Shi, Ying, Kong, Ying, Chen, Jingyuan, Zhang, Lifang, Li, Yongxin, Galvin III, John J., and Fu, Qian-Jie
- Subjects
COCHLEAR implants ,SPEECH perception ,HEARING ,PHYSIOLOGICAL aspects of speech ,MASKING (Psychology) ,NOISE ,SPEECH audiometry ,FACTOR analysis ,DESCRIPTIVE statistics ,PROMPTS (Psychology) - Abstract
Different from normal-hearing (NH) listeners, speech recognition thresholds (SRTs) in cochlear implant (CI) users are typically poorer with dynamic maskers than with speech-spectrum noise (SSN). The effectiveness of different masker types may depend on their acoustic and linguistic characteristics. The goal of the present study was to evaluate the effectiveness of different masker types with varying acoustic and linguistic properties in CI and NH listeners. SRTs were measured with nine maskers, including SSN, dynamic nonspeech maskers, and speech maskers with or without lexical content. Results showed that CI users performed significantly poorer than NH listeners with all maskers. NH listeners were much more sensitive to masker type than were CI users. Relative to SSN, NH listeners experienced significant masking release for most maskers, which could be well explained by the glimpse proportion, especially for maskers containing similar cues related to fundamental frequency or lexical content. In contrast, CI users generally experienced negative masking release. There was significant intercorrelation among the maskers for CI users' SRTs but much less so for NH listeners' SRTs. Principal component analysis showed that one factor explained 72% of the variance in CI users' SRTs but only 55% in NH listeners' SRTs across all maskers. Taken together, the results suggest that SRTs in SSN largely accounted for the variability in CI users' SRTs with dynamic maskers. Different from NH listeners, CI users appear to be more susceptible to energetic masking and do not experience a release from masking with dynamic envelopes or speech maskers. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
26. Assessment of the correlation between residual hearing and audiologic outcomes after cochlear implantation in patients with cochlear nerve deficiency.
- Author
-
Lu, Simeng, Wei, Xingmei, Kong, Ying, Chen, Biao, Chen, Jingyuan, Zhang, Lifang, Yang, Mengge, Liu, Sha, and Li, Yongxin
- Subjects
COCHLEAR implants ,ACOUSTIC nerve ,INTELLIGIBILITY of speech ,SPEECH perception ,HEARING levels ,HEARING impaired - Abstract
Objective: This study aimed to assess the correlation between residual hearing and audiologic outcomes after cochlear implant (CI) surgery in patients with cochlear nerve deficiency (CND). Methods: This retrospective study included 57 patients with CND who underwent CI surgery. Patients were divided into four groups according to hearing level (80–95, 95–110, 110–120, and >120 dB) and three groups according to residual hearing (entire spectrum hearing, partial spectrum hearing, and no spectrum hearing) based on the measured response at each frequency. Auditory performance (categorical auditory performance [CAP], Infant–Toddler Meaningful Auditory Integration Scale [IT‐MAIS]) and speech perception (speech intelligibility rating [SIR] and meaningful use of speech scale [MUSS]) were assessed before and 2 years after the surgery. Results: Forty‐seven (82.5%) patients had complete or total hearing loss (≥95 dB) and 17 (29.8%) had no spectrum hearing before CI surgery. Twenty‐nine (50.9%) patients did not exhibit residual hearing at 4 kHz. All patients demonstrated an improvement in auditory performance and speech perception: the CAP score in the 80–95 dB group was significantly higher than that in the 110–120 and >120 dB groups, and the entire spectrum hearing group showed significantly higher CAP, SIR, and IT‐MAIS scores than the partial spectrum hearing group and significantly higher CAP, SIR, IT‐MAIS, and MUSS scores than the no spectrum hearing group. Conclusion: For patients with CND, residual hearing, especially high‐frequency residual hearing, was poor and postoperative audiologic outcomes were significantly associated with the range of residual hearing. Level of Evidence: 4 [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
27. Machine Learning-Based Prediction of the Outcomes of Cochlear Implantation in Patients With Cochlear Nerve Deficiency and Normal Cochlea: A 2-Year Follow-Up of 70 Children.
- Author
-
Lu, Simeng, Xie, Jin, Wei, Xingmei, Kong, Ying, Chen, Biao, Chen, Jingyuan, Zhang, Lifang, Yang, Mengge, Xue, Shujin, Shi, Ying, Liu, Sha, Xu, Tianqiu, Dong, Ruijuan, Chen, Xueqing, Li, Yongxin, and Wang, Haihui
- Subjects
ACOUSTIC nerve ,COCHLEAR implants ,COCHLEA ,INTELLIGIBILITY of speech ,SUPPORT vector machines ,FEATURE selection - Abstract
Cochlear nerve deficiency (CND) is often associated with variable outcomes of cochlear implantation (CI). We assessed previous investigations aiming to identify the main factors that determine CI outcomes, which would enable us to develop predictive models. Seventy patients with CND and normal cochlea who underwent CI surgery were retrospectively examined. First, using a data-driven approach, we collected demographic information, radiographic measurements, audiological findings, and audition and speech assessments. Next, CI outcomes were evaluated based on the scores obtained after 2 years of CI from the Categories of Auditory Performance index, Speech Intelligibility Rating, Infant/Toddler Meaningful Auditory Integration Scale or Meaningful Auditory Integration Scale, and Meaningful Use of Speech Scale. Then, we measured and averaged the audiological and radiographic characteristics of the patients to form feature vectors, adopting a multivariate feature selection method, called stability selection, to select the features that were consistent within a certain range of model parameters. Stability selection analysis identified two out of six characteristics, namely the vestibulocochlear nerve (VCN) area and the number of nerve bundles, which played an important role in predicting the hearing and speech rehabilitation results of CND patients. Finally, we used a parameter-optimized support vector machine (SVM) as a classifier to study the postoperative hearing and speech rehabilitation of the patients. For hearing rehabilitation, the accuracy rate was 71% for both the SVM classification and the area under the curve (AUC), whereas for speech rehabilitation, the accuracy rate for SVM classification and AUC was 93% and 94%, respectively. Our results identified that a greater number of nerve bundles and a larger VCN area were associated with better CI outcomes. The number of nerve bundles and VCN area can predict CI outcomes in patients with CND. These findings can help surgeons in selecting the side for CI and provide reasonable expectations for the outcomes of CI surgery. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
28. Analysis of Long-Term Cochlear Implantation Outcomes and Correlation With Imaging Characteristics in Patients With Common Cavity Deformity.
- Author
-
Zhang, Lifang, Chen, Biao, Kong, Ying, Liau, Natalia, Wei, Xingmei, Shi, Ying, Chen, Jingyuan, Yang, Mengge, Dhanasingh, Anandhan, and Li, Yongxin
- Subjects
COCHLEAR implants ,INTELLIGIBILITY of speech ,INNER ear ,PLASTIC surgery ,HUMAN abnormalities ,SPEECH - Abstract
Object: To investigate the long-term development of auditory and speech in patients with common cavity deformity (CCD) after cochlear implantation (CI) and its relationship to imaging characteristics. Methods: Twenty-three CCD patients and 59 age- and sex-matched CI children with normal inner ear structure were recruited. The auditory and speech development of these two groups were evaluated at 0, 1, 3, 6, 12, and 18 months after CI activation using four parent reports questionnaires [Categories of Auditory Performance (CAP), Speech Intelligibility Rating (SIR), Meaningful Auditory Integration Scale/Infant-Toddler Meaningful Auditory Integration Scale (MAIS/ITMAIS), and Meaningful Use of Speech Scale (MUSS)]. Computed tomography-based 3-dimensional reconstruction of the surgical side of 18 CCD children was performed, the volume and surface area were calculated. Correlation analysis was performed on the imaging performance and post-operative outcomes. Results: The percentages of MAIS/IT-MAIS scores and CAP scores at different evaluation time points are significantly different (p < 0.05). When comparing SIR results across time points, significant growth was observed in most of the comparisons. In addition, significant differences (p < 0.05) are observed among the percentages of MUSS scores at different time points except the comparison between 0 and 1 month after CI activation. Patients in the CCD group had poorer auditory and speech performances at different stages after CI compared with those in the control group. According to the reconstruction of CCD patients, the volume ranged from 12.21 to 291.96 mm
3 ; the surface area ranged from 27.81 to 284.7 mm2 . When the lumen surface area was <190.45 mm2 or the volume was <157.91 mm3 , the survival time for CCD children to achieve a CAP score of 4 after CI was significantly shorter. Conclusion: Cochlear implantation are less effective in CCD patients than in patients with normal inner ear structures, but they can still achieve significant improvement post-operatively. The morphology and size of the inner ear vary in CCD patients, which reflects the degree of inner ear development influences the outcome after CI surgery. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
29. Application of Multiplanar Volume Reconstruction Technique for the Assessment of Electrode Location and Analysis of the Correlation to Cochlear Programming and Performance in Common Cavity Deformity.
- Author
-
Wei, Xingmei, Zhang, Huaiyu, Lu, Simeng, Yang, Mengge, Chen, Biao, Chen, Jingyuan, Zhang, Lifang, Liu, Sha, Xian, Junfang, Li, Yongxin, and Kong, Ying
- Subjects
LOCATION analysis ,VESTIBULAR nerve ,VESTIBULAR stimulation ,FACIAL nerve ,NEURAL stimulation ,ELECTRICAL impedance tomography ,COCHLEAR implants - Abstract
Purpose: Owing to the characteristic anatomy, cochlear implantation (CI) for common cavity deformity (CCD) has resulted in varied outcomes and frequent facial and vestibular nerve stimulation. The current study analyzed the correlation among the distance between each electrode and cavity wall (abbreviation, D), programming parameters, and performances outcomes. Materials and Methods: The current, retrospective study included 25 patients (27 ears) with CCD underwent CI. The multiplanar volume reconstruction (MPVR) techniques were employed to reconstruct and evaluate the postoperative temporal bone CT. The D and maximum comfortable level (MCL) 6 months after CI, facial and vestibular nerve stimulation, and outcomes 1, 2, and 3 years after CI pertaining to the questionnaires were documented and analyzed. Results: The patients were divided into symptomatic (10, 37%) and asymptomatic (17, 63%) groups according to with or without facial and vestibular nerve stimulation. The MCL pertaining to the symptomatic group was significantly lower than asymptomatic group, but Categories of Auditory Performance (CAP) scores 1 year after surgery was better (p < 0.05). The subjects were divided into flat (12, 44.4%) and curved (15, 55.6%) groups based on the contour of MCL map. The MCL and D were lower and shorter in the curved group than the flat group, and CAP score 1 year after surgery and Speech Intelligibility Rating (SIR) 3 years after surgery were better (p < 0.05). Conclusion: Although abnormal reactions such as facial and vestibular nerve stimulation were observed to be more frequent, lower MCL and better outcomes were observed in relation to the shorter D. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
30. Speech development after cochlear implantation in infants with isolated large vestibular aqueduct syndrome.
- Author
-
Li, Yang, Kong, Ying, Xu, Tianqiu, Dong, Ruijuan, Lv, Jing, Qi, Beier, Wang, Shuo, Yan, Fei, Li, Yongxin, Long, Mo, and Chen, Xueqing
- Subjects
DIAGNOSIS of deafness ,COCHLEAR implants ,COMMUNICATIVE competence ,LANGUAGE acquisition ,POSTOPERATIVE period ,SPEECH evaluation ,VESTIBULAR apparatus diseases ,TREATMENT effectiveness ,SEVERITY of illness index ,VESTIBULAR aqueduct ,CHILDREN - Abstract
Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
31. The Development of Auditory Skills in Young Children with Mondini Dysplasia after Cochlear Implantation.
- Author
-
Chen, Xueqing, Yan, Fei, Liu, Bo, Liu, Sha, Kong, Ying, Zheng, Jun, Li, Yongxin, Gong, Shusheng, Han, Demin, and Zhang, Luo
- Subjects
COCHLEAR implants ,DYSPLASIA ,OTOLARYNGOLOGY ,JUVENILE diseases ,AUDIOLOGY ,COMPARATIVE studies ,THERAPEUTICS - Abstract
The aim of this study is to survey and compare the development of auditory skills in young children with Mondini dysplasia and profoundly-deaf young children with radiologically normal inner ears over a period of 3 years after cochlear implantation. A total of 545 young children (age 7 to 36 months) with prelingual, severe to profound hearing loss participated in this study. All children received cochlear implantation. Based on whether or not there was a Mondini dysplasia as diagnosed with CT scanning, the subjects were divided into 2 groups: (A) 514 young children with radiologically normal inner ears and (B) 31 young children with Mondini dysplasia. The Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS) was used to assess the children's auditory skills that include vocalization changes, spontaneous alerting to sounds in everyday living environments, and the ability to derive meaning from sounds. The assessment was performed prior to surgery and at 1, 3, 6, 9, 12, 24, and 36 months after implant device switch-on. The mean scores for overall auditory skills were not significantly different between groups A and B at pre-surgery, 1, 12, 24, and 36 months post-surgery, but were significantly different at 3, 6, and 9 months post-surgery. The mean scores for all auditory skills in children with Mondini dysplasia showed significant improvement over time. The mean scores for the three subcategories of auditory skills in children with Mondini dysplasia also showed significant differences at pre-surgery, 1, 3, 6, and 9 months, however, there were no significant differences at 12, 24, and 36 months. Overall, the auditory skills of young children with Mondini dysplasia developed rapidly after cochlear implantation, in a similar manner to that of young children with radiologically normal inner ears. Cochlear implantation is an effective intervention for young children with Mondini dysplasia. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
32. Tone perception and production in pediatric cochlear implants users.
- Author
-
Xu, Li, Chen, Xiuwu, Lu, Hongyun, Zhou, Ning, Wang, Shuo, Liu, Qiaoyun, Li, Yongxin, Zhao, Xiaoyan, and Han, Demin
- Subjects
EAR surgery ,ANALYSIS of variance ,AUDITORY perception ,AUDITORY perception testing ,COCHLEAR implants ,DEAFNESS ,LANGUAGE & languages ,RESEARCH funding ,PHYSIOLOGICAL aspects of speech - Abstract
Conclusions: In prelingually deaf children with cochlear implants, tone perception and production performance are highly correlated. This result is consistent with the hypothesis that tone perception is the prerequisite for good tone production. Objectives: Previous research has shown remarkable deficits in tone perception and production in native tone language-speaking, prelingually deafened children with cochlear implants. The purpose of the present study was to investigate the relationship between tone perception and production in those children. Methods: Twenty-five prelingually deaf children with cochlear implants participated in the study. All subjects were Advanced Bionics CII/90K users with various lengths of implant use. To evaluate tone perception performance, subjects completed a computerized tone contrast test. For tone production performance, an artificial neural network was used to evaluate the accuracy of tones recorded from each of the 25 subjects. Results: Large individual differences in tone perception and production performance were observed in these subjects. Tone perception accuracy ranged from 50.0 to 96.9% correct (chance performance == 50% correct; mean == 71.0% correct). Tone production performance ranged from 19.4 to 97.2% correct (mean == 52.0% correct). A strong correlation was found between tone perception and production performance in this group of subjects ( r == 0.805). [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
33. A New Pathogenic Variant in POU3F4 Causing Deafness Due to an Incomplete Partition of the Cochlea Paved the Way for Innovative Surgery.
- Author
-
Tekin, Ahmet M., Matulic, Marco, Wuyts, Wim, Assadi, Masoud Zoka, Mertens, Griet, Rompaey, Vincent van, Li, Yongxin, Heyning, Paul van de, Topsakal, Vedat, Ophoff, Roel, and Schrauwen, Isabelle
- Subjects
COCHLEA ,COCHLEAR implants ,SENSORINEURAL hearing loss ,EAR canal ,INNER ear ,GENETIC mutation - Abstract
Incomplete partition type III (IP-III) is a relatively rare inner ear malformation that has been associated with a POU3F4 gene mutation. The IP-III anomaly is mainly characterized by incomplete separation of the modiolus of the cochlea from the internal auditory canal. We describe a 71-year-old woman with profound sensorineural hearing loss diagnosed with an IP-III of the cochlea that underwent cochlear implantation. Via targeted sequencing with a non-syndromic gene panel, we identified a heterozygous c.934G > C p. (Ala31Pro) pathogenic variant in the POU3F4 gene that has not been reported previously. IP-III of the cochlea is challenging for cochlear implant surgery for two main reasons: liquor cerebrospinalis gusher and electrode misplacement. Surgically, it may be better to opt for a shorter array because it is less likely for misplacement with the electrode in a false route. Secondly, the surgeon has to consider the insertion angles of cochlear access very strictly to avoid misplacement along the inner ear canal. Genetic results in well describes genotype-phenotype correlations are a strong clinical tool and as in this case guided surgical planning and robotic execution. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
34. Cochlear implant surgery through oval window: A novel approach in a child with facial nerve aberration.
- Author
-
Chen, Biao, Li, Yongxin, Lu, Simeng, Chen, Jingyuan, Shi, Ying, Cui, Danmo, Zhang, Lifang, and Xie, Jing
- Subjects
- *
FACIAL nerve , *SPEECH perception , *COCHLEAR implants , *SURGICAL complications , *SURGERY - Abstract
Cochlear implantation is safe for simple case presentations. However, facial nerve (FN) aberrations may impede insertion of the electrode through a round window and increase the risk of iatrogenic FN injury. We developed a novel method of cochlear implantation, a present the case of a child with FN aberrations. Inferior displacement of a horizontal segment of FN lay on the surface of th e promontory, obscuring the round window. The oval window was used and the electrode successfully inserted. No postoperative complications occurred, and significant improvement in speech perception was achieved. This novel approach is suitable for patients with FN aberrations. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
35. Trends in research on cochlear implantation with inner ear malformation: a bibliometric and visualization analysis from 1986 to 2024.
- Author
-
Xue, Shujin, Wei, Xingmei, Kong, Ying, Chen, Biao, Chen, Jingyuan, and Li, Yongxin
- Subjects
- *
INNER ear physiology , *COCHLEAR implants , *BIBLIOMETRICS , *CHILD patients - Abstract
Objective: The aim of this study was to conduct a bibliometric and visualization analysis of research on cochlear implantation (CI) for inner ear malformations (IEMs) from 1986 to 2024.A comprehensive literature search was performed using the Web of Science Core Collection Database, resulting in the identification of 431 relevant publications. Various data analysis and visualization tools, including VOSviewer, CiteSpace, and Bibliometrix, were utilized to analyze annual publication outputs, countries/regions and institutions, authors, journals and studies, keywords, and theme evolution.The study revealed an overall increasing trend in research output on CI for IEMs, with significant contributions from countries such as the United States, China, Turkey, Germany, and Italy. The analysis also identified key authors, research teams, journals, and studies that have made substantial contributions to the field. Furthermore, the study highlighted important research hotspots and trends, such as the classification of IEMs, outcomes of CI for IEMs, and the management of pediatric patients with IEMs.The findings of this study provide a comprehensive overview of the research landscape surrounding CI for IEMs. The results serve as a basis for future research topic selection and emphasize the need for enhanced international collaboration and the publication of high-impact research to further advance this field.Methods: The aim of this study was to conduct a bibliometric and visualization analysis of research on cochlear implantation (CI) for inner ear malformations (IEMs) from 1986 to 2024.A comprehensive literature search was performed using the Web of Science Core Collection Database, resulting in the identification of 431 relevant publications. Various data analysis and visualization tools, including VOSviewer, CiteSpace, and Bibliometrix, were utilized to analyze annual publication outputs, countries/regions and institutions, authors, journals and studies, keywords, and theme evolution.The study revealed an overall increasing trend in research output on CI for IEMs, with significant contributions from countries such as the United States, China, Turkey, Germany, and Italy. The analysis also identified key authors, research teams, journals, and studies that have made substantial contributions to the field. Furthermore, the study highlighted important research hotspots and trends, such as the classification of IEMs, outcomes of CI for IEMs, and the management of pediatric patients with IEMs.The findings of this study provide a comprehensive overview of the research landscape surrounding CI for IEMs. The results serve as a basis for future research topic selection and emphasize the need for enhanced international collaboration and the publication of high-impact research to further advance this field.Results: The aim of this study was to conduct a bibliometric and visualization analysis of research on cochlear implantation (CI) for inner ear malformations (IEMs) from 1986 to 2024.A comprehensive literature search was performed using the Web of Science Core Collection Database, resulting in the identification of 431 relevant publications. Various data analysis and visualization tools, including VOSviewer, CiteSpace, and Bibliometrix, were utilized to analyze annual publication outputs, countries/regions and institutions, authors, journals and studies, keywords, and theme evolution.The study revealed an overall increasing trend in research output on CI for IEMs, with significant contributions from countries such as the United States, China, Turkey, Germany, and Italy. The analysis also identified key authors, research teams, journals, and studies that have made substantial contributions to the field. Furthermore, the study highlighted important research hotspots and trends, such as the classification of IEMs, outcomes of CI for IEMs, and the management of pediatric patients with IEMs.The findings of this study provide a comprehensive overview of the research landscape surrounding CI for IEMs. The results serve as a basis for future research topic selection and emphasize the need for enhanced international collaboration and the publication of high-impact research to further advance this field.Conclusion: The aim of this study was to conduct a bibliometric and visualization analysis of research on cochlear implantation (CI) for inner ear malformations (IEMs) from 1986 to 2024.A comprehensive literature search was performed using the Web of Science Core Collection Database, resulting in the identification of 431 relevant publications. Various data analysis and visualization tools, including VOSviewer, CiteSpace, and Bibliometrix, were utilized to analyze annual publication outputs, countries/regions and institutions, authors, journals and studies, keywords, and theme evolution.The study revealed an overall increasing trend in research output on CI for IEMs, with significant contributions from countries such as the United States, China, Turkey, Germany, and Italy. The analysis also identified key authors, research teams, journals, and studies that have made substantial contributions to the field. Furthermore, the study highlighted important research hotspots and trends, such as the classification of IEMs, outcomes of CI for IEMs, and the management of pediatric patients with IEMs.The findings of this study provide a comprehensive overview of the research landscape surrounding CI for IEMs. The results serve as a basis for future research topic selection and emphasize the need for enhanced international collaboration and the publication of high-impact research to further advance this field. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
36. Characteristics of vestibular-evoked myogenic potentials in children with vestibular malformation and severe sensorineural hearing loss.
- Author
-
Shen, Mengya, Xue, Shujin, Wei, Xingmei, Chen, Biao, Kong, Ying, and Li, Yongxin
- Subjects
- *
SENSORINEURAL hearing loss , *INNER ear physiology , *VESTIBULAR apparatus diseases , *HUMAN abnormalities , *COCHLEAR implants - Abstract
With the increasing clinical focus on the safety of bilateral cochlear implantation (CI) and the potential risk of bilateral vestibular dysfunction, evaluating vestibular end-organ function in patients with vestibular malformations with accompanying abnormalities has been strongly recommended. To identify the vestibular-evoked myogenic potential (VEMP) values among children with sensorineural hearing loss (SNHL) with vestibular malformation and assess the effectiveness of VEMP testing for inner ear malformations (IEM) diagnosis. This study included 96 children (192 ears), including those with vestibular malformations (48 ears), large vestibular aqueduct syndrome (LVAS) (50 ears), and SNHL without IEM (94 ears; control group). All groups underwent ocular and cervical VEMP (oVEMP and cVEMP, respectively) testing. The response rates, VEMP parameters, and wave characteristics were compared. The cVEMP response rates were 37.5 %, 64 %, and 58.51 % and the oVEMP response rates were 42.86 %, 78.95 %, and 77.27 % in the vestibular malformation, LVAS, and control groups, respectively, and significantly differed between groups (cVEMP: X 2 = 18.228, P< 0.001) (oVEMP: X 2 = 7.528, P = 0.023). Significant inter-group differences were observed for the cVEMP and oVEMP latency and amplitude (P < 0.05). The LVAS group's waveform exhibited a prolonged latency and increased amplitude compared with that of the other groups. Patients with SNHL were highly susceptible to otolith dysfunction, regardless of comorbid vestibular malformation presence. Measuring VEMPs is an effective and rapid evaluation technique for vestibular function and could provide a basis for vestibular rehabilitation training. • Studies of characteristics of VEMPs waveform in severe SNHL and vestibular malformations are limited. • Vestibular-evoked myogenic potential (VEMP) testing is an effective and rapid method for measuring saccule and utricle function. • The cVEMP and oVEMP response rate of the vestibular malformation group was significantly low. • Patients with SNHL were highly susceptible to otolith dysfunction. • Results of VEMP testing could improve the classification of vestibular malformations and allow further characterization of IEM subsets. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
37. Interaction between speech variations and background noise on speech intelligibility by Mandarin-speaking cochlear implant patients.
- Author
-
Shi, Ying, Peng, Kevin A., Chen, Biao, Gong, Yue, Chen, Jingyuan, Li, Yongxin, and Fu, Qian-Jie
- Subjects
- *
COCHLEAR implants , *PROSODIC analysis (Linguistics) , *VERSIFICATION , *AUTOMATIC speech recognition , *SPEECH processing systems - Abstract
Abstract Cochlear implant (CI) users have been shown to be more susceptible to the variations in speech production encountered in everyday listening, in which speaking rate, amplitude, duration, and voice pitch information may be quite variable, depending on the production context. Such variations may be further enlarged by the background noise, especially dynamic noise. The limited spectral resolution provided by the CI limits perception of voice pitch, which is an important cue for speech prosody and for tonal languages such as Mandarin Chinese. In this study, the effect of varying speaking rates and styles and background noise on speech understanding was investigated in Mandarin-speaking CI and normal-hearing (NH) listeners. Thirteen (5 male and 8 female, age 19–62 years) Mandarin-speaking, post-lingually deafened adult CI patients using their clinical processors and 9 (5 male and 4 female, age 23–59 years) NH subjects listening to unprocessed speech. Five different types of speech variations, including 3 speaking rates (slow, normal, fast) and 2 speaking styles (emotional, shouted) were presented with two masking noises (speech-shaped steady state noise-SSN or six-talker babble). Speech reception threshold, defined as the signal-to-noise ratio producing 50% correct word-in-sentence recognition using Mandarin Speech Perception materials was measured. NH listeners performed significantly better (16.7 dB) than CI patients across all conditions regardless of speech variations and noise types. CI patients' performance deficit was highly dependent on speech rate and noise type; the deficit was smallest (11.7 dB) when slowly-spoken speech was presented in SSN and largest (20.6 dB) when shouted speech was presented in six-talker speech babble. NH listeners performed significantly better in speech babble than in SSN for all speech variations, while CI patients performed similarly in both noise types. The use of clear and slowly-spoken speech in the laboratory setting may largely underestimate CI patients' performance deficits in real-world listening conditions, where acoustic variations introduced by speech variations and dynamic noise may present additional challenges. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
38. Effect of age at cochlear implantation on auditory and speech development of children with auditory neuropathy spectrum disorder.
- Author
-
Liu, Yuying, Dong, Ruijuan, Li, Yuling, Xu, Tianqiu, Li, Yongxin, Chen, Xueqing, and Gong, Shusheng
- Subjects
- *
COCHLEAR implants , *AGE factors in disease , *AUDITORY perception , *NEUROPATHY , *MAGNETIC resonance imaging , *PATIENTS ,ACOUSTIC nerve diseases - Abstract
Objective To evaluate the auditory and speech abilities in children with auditory neuropathy spectrum disorder (ANSD) after cochlear implantation (CI) and determine the role of age at implantation. Methods Ten children participated in this retrospective case series study. All children had evidence of ANSD. All subjects had no cochlear nerve deficiency on magnetic resonance imaging and had used the cochlear implants for a period of 12–84 months. We divided our children into two groups: children who underwent implantation before 24 months of age and children who underwent implantation after 24 months of age. Their auditory and speech abilities were evaluated using the following: behavioral audiometry, the Categories of Auditory Performance (CAP), the Meaningful Auditory Integration Scale (MAIS), the Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS), the Standard-Chinese version of the Monosyllabic Lexical Neighborhood Test (LNT), the Multisyllabic Lexical Neighborhood Test (MLNT), the Speech Intelligibility Rating (SIR) and the Meaningful Use of Speech Scale (MUSS). Results All children showed progress in their auditory and language abilities. The 4-frequency average hearing level (HL) (500 Hz, 1000 Hz, 2000 Hz and 4000 Hz) of aided hearing thresholds ranged from 17.5 to 57.5 dB HL. All children developed time-related auditory perception and speech skills. Scores of children with ANSD who received cochlear implants before 24 months tended to be better than those of children who received cochlear implants after 24 months. Seven children completed the Mandarin Lexical Neighborhood Test. Approximately half of the children showed improved open-set speech recognition. Conclusion Cochlear implantation is helpful for children with ANSD and may be a good optional treatment for many ANSD children. In addition, children with ANSD fitted with cochlear implants before 24 months tended to acquire auditory and speech skills better than children fitted with cochlear implants after 24 months. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
39. The development of auditory skills in infants with isolated Large Vestibular Aqueduct Syndrome after cochlear implantation
- Author
-
Chen, Xueqing, Liu, Bo, Liu, Sha, Mo, Lingyan, Liu, Haihong, Dong, Ruijuan, Li, Yongxin, Gong, Shusheng, Han, Demin, and Zhang, Luo
- Subjects
- *
HEARING disorders in infants , *EAR canal , *COCHLEAR implants , *INNER ear , *DIAGNOSIS of deafness , *SYNDROMES , *SURGERY - Abstract
Abstract: Objective: The purpose of this study was to investigate the auditory performance of infants with isolated Large Vestibular Aqueduct Syndrome (LVAS) after cochlear implantation, compare their performance with those of infants with a normal inner ear, and establish a database of auditory development. Method: 435 infants with congenital severe to profound hearing loss participated in this study. 62 infants in group A were diagnosed with isolated LVAS. 373 infants in group B had a normal inner ear. Infant–Toddler Meaningful Auditory Integration Scale (IT-MAIS) was used to evaluate the development of auditory skills. Results: The mean scores for auditory ability showed no significant difference between groups A and B. The mean scores for the three different auditory skills increased significantly over time. The differences were statistically significant in mean scores among the three different auditory skills for group B. Conclusion: Auditory skills of infants with isolated LVAS developed rapidly after cochlear implantation, in a similar manner to those of infants with a normal inner ear. Cochlear implantation is an effective interventional approach and an established therapeutic option for infants with isolated LVAS. [Copyright &y& Elsevier]
- Published
- 2011
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.