Search

Guide rails’ nonlinear dynamic response to the collision process between gangues and the suspended buffer is the basis for its intensity examination and fatigue prediction. This paper established a numerical model for simulating the dynamic response of buffer’s guide rails using Pro/E and Femap based on an analysis of the basic structural components of the suspended buffer. The effects of the gangues diameter and feeding rate on the guide rails’ dynamic response were investigated, which were mainly revealed by a tension in guide rails. Simulation results showed that the tension in guide rails rapidly increased to a peak value after the suspended buffer was impacted by gangues, followed by a periodic vibration. The peak tension, maximum and minimum tensions within the periodic vibration were exponential functions of the gangues diameter. And they depended linearly on the feeding rate. The vibration frequency of the tension in guide rails was an exponential function of the gangues diameter but did not depend on the feeding rate. Based on the backfilling workface parameters used in D.Ping coal miner’s 15601 working panel, the feeding rate of 500 t/h was selected. The diameter of the crushed gangues was selected to be 50 mm based on the strength of guide rails. Their expected service life is 54.2 years. Finally, an industrial test was performed in D.Ping coal miner’s 15601 working panel and the guide rails operated steadily. The measured vibration parameters of the tension in guide rails agree well with that of numerical predictions, which verified the reliability of the numerical model to some extent. [ABSTRACT FROM AUTHOR]

This paper describes a web server developed for designing therapeutic peptides with desired half-life in blood. In this study, we used 163 natural and 98 modified peptides whose half-life has been determined experimentally in mammalian blood, for developing in silico models. Firstly, models have been developed on 261 peptides containing natural and modified residues, using different chemical descriptors. The best model using 43 PaDEL descriptors got a maximum correlation of 0.692 between the predicted and the actual half-life peptides. Secondly, models were developed on 163 natural peptides using amino acid composition feature of peptides and achieved a maximum correlation of 0.643. Thirdly, models were developed on 163 natural peptides using chemical descriptors and attained a maximum correlation of 0.743 using 45 selected PaDEL descriptors. In order to assist researchers in the prediction and designing of half-life of peptides, the models developed have been integrated into PlifePred web server (). [ABSTRACT FROM AUTHOR]

The atom-bond connectivity index (or, for short, ABC index) is a molecular structure descriptor bridging chemistry to graph theory. It is probably the most studied topological index among all numerical parameters of a graph that characterize its topology. For a given graph G = (V, E), the ABC index of G is defined as , where di denotes the degree of the vertex i, and ij is the edge incident to the vertices i and j. A combination of physicochemical and the ABC index properties are commonly used to foresee the bioactivity of different chemical composites. Additionally, the applicability of the ABC index in chemical thermodynamics and other areas of chemistry, such as in dendrimer nanostars, benzenoid systems, fluoranthene congeners, and phenylenes is well studied in the literature. While finding of the graphs with the greatest ABC-value is a straightforward assignment, the characterization of the tree(s) with minimal ABC index is a problem largely open and has recently given rise to numerous studies and conjectures. A B1-branch of a graph is a pendent path of order 2. In this paper, we provide an important step forward to the full characterization of these minimal trees. Namely, we show that a minimal-ABC tree contains neither 4 nor 3 B1-branches. The case when the number of B1-branches is 2 is also considered. [ABSTRACT FROM AUTHOR]

Using the spectrum data for quality prediction always suffers from noise and colinearity, so variable selection method plays an important role to deal with spectrum data. An efficient elastic net with regression coefficients method (Enet-BETA) is proposed to select the significant variables of the spectrum data in this paper. The proposed Enet-BETA method can not only select important variables to make the quality easy to interpret, but also can improve the stability and feasibility of the built model. Enet-BETA method is not prone to overfitting because of the reduction of redundant variables realized by elastic net method. Hypothesis testing is used to further simplify the model and provide a better insight into the nature of process. The experimental results prove that the proposed Enet-BETA method outperforms the other methods in terms of prediction performance and model interpretation. [ABSTRACT FROM AUTHOR]

Spatial-temporal k-anonymity has become a mainstream approach among techniques for protection of users’ privacy in location-based services (LBS) applications, and has been applied to several variants such as LBS snapshot queries and continuous queries. Analyzing large-scale spatial-temporal anonymity sets may benefit several LBS applications. In this paper, we propose two location prediction methods based on transition probability matrices constructing from sequential rules for spatial-temporal k-anonymity dataset. First, we define single-step sequential rules mined from sequential spatial-temporal k-anonymity datasets generated from continuous LBS queries for multiple users. We then construct transition probability matrices from mined single-step sequential rules, and normalize the transition probabilities in the transition matrices. Next, we regard a mobility model for an LBS requester as a stationary stochastic process and compute the n-step transition probability matrices by raising the normalized transition probability matrices to the power n. Furthermore, we propose two location prediction methods: rough prediction and accurate prediction. The former achieves the probabilities of arriving at target locations along simple paths those include only current locations, target locations and transition steps. By iteratively combining the probabilities for simple paths with n steps and the probabilities for detailed paths with n-1 steps, the latter method calculates transition probabilities for detailed paths with n steps from current locations to target locations. Finally, we conduct extensive experiments, and correctness and flexibility of our proposed algorithm have been verified. [ABSTRACT FROM AUTHOR]

The performance of objective speech and audio quality measures for the prediction of the perceived quality of frequency-compressed speech in hearing aids is investigated in this paper. A number of existing quality measures have been applied to speech signals processed by a hearing aid, which compresses speech spectra along frequency in order to make information contained in higher frequencies audible for listeners with severe high-frequency hearing loss. Quality measures were compared with subjective ratings obtained from normal hearing and hearing impaired children and adults in an earlier study. High correlations were achieved with quality measures computed by quality models that are based on the auditory model of Dau et al., namely, the measure PSM, computed by the quality model PEMO-Q; the measure qc, computed by the quality model proposed by Hansen and Kollmeier; and the linear subcomponent of the HASQI. For the prediction of quality ratings by hearing impaired listeners, extensions of some models incorporating hearing loss were implemented and shown to achieve improved prediction accuracy. Results indicate that these objective quality measures can potentially serve as tools for assisting in initial setting of frequency compression parameters. [ABSTRACT FROM AUTHOR]